JAK2

General Information

Gene Name : JAK2
Gene ID : ENSG00000096968.13
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: JAK2)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	JAK2	ENSG00000096968.13	15.32	11.79	13.55	ENCSR000AEF
HepG2	JAK2	ENSG00000096968.13	1.14	1.91	1.52	ENCSR985KAT
K562	JAK2	ENSG00000096968.13	9.15	10.26	9.71	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for JAK2 is not avaliable on ENCORE database.

Proteins bound to RNA

JAK2 RNA is bound by 29 proteins.

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eCLIP assay for JAK2 is not avaliable on ENCORE database.

29 proteins are bound to JAK2 RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr9	5100130	5100172	+	intron-Distal	6.90771	45.39297	K562	QKI
chr9	5100296	5100419	+	intron-Distal	6.24562	24.14083	K562	QKI
chr9	5127372	5127428	+	3'-UTR	5.52419	22.65351	K562	PUM2
chr9	5095895	5096016	+	intron-Distal	5.61733	21.83010	K562	QKI
chr9	5127117	5127185	+	3'-UTR	4.81631	15.28381	K562	PUM2
chr9	5020527	5020609	+	intron-Distal	4.21228	15.09791	K562	EXOSC5
chr9	5049695	5049828	+	intron-Distal	4.80167	14.84917	K562	KHSRP
chr9	5065912	5065981	+	intron-Distal	5.19656	14.84917	K562	KHSRP
chr9	5095788	5095892	+	intron-Distal	5.56639	14.42007	K562	QKI
chr9	5095504	5095554	+	intron-Distal	5.46014	12.81155	K562	QKI
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 138 entries

eCLIP assay for JAK2 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for JAK2 is not available on ENCORE database.
91 RBPs can affect the levels of JAK2.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for JAK2 is not available on ENCORE database.

91 RBPs can affect the gene expression of JAK2 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
JAK2	ENSG00000096968.8	2551.00640	1163.24110	1.13280	30.55860	27.88600	K562	WDR3
JAK2	ENSG00000096968.8	2140.13380	1209.62410	0.82300	28.23960	26.02040	K562	WDR43
JAK2	ENSG00000096968.8	617.86110	130.58450	2.24220	23.64630	21.79090	HepG2	RAVER1
JAK2	ENSG00000096968.8	371.03190	139.36630	1.41260	19.27730	17.98790	HepG2	ACO1
JAK2	ENSG00000096968.8	471.39980	205.74420	1.19600	16.76990	15.80980	HepG2	SRFBP1
JAK2	ENSG00000096968.8	352.15710	109.07910	1.69070	16.80470	15.20420	HepG2	U2AF1
JAK2	ENSG00000096968.8	542.72660	185.87550	1.54580	16.25640	15.07770	HepG2	AKAP1
JAK2	ENSG00000096968.8	875.93450	1483.00490	-0.75960	15.93280	14.58990	K562	FXR1
JAK2	ENSG00000096968.8	2621.79720	1591.46260	0.72010	15.16380	13.25800	K562	U2AF2
JAK2	ENSG00000096968.8	295.44010	103.23890	1.51680	14.38010	12.69210	HepG2	MSI2
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 106 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for JAK2 is not available on ENCORE database.

5 RBPs can affect the splicing of JAK2 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	JAK2	ENSG00000096968.8	chr9	+	5126332	5126446			5123003	5123121	5126683	5126814	-0.15800	0.00000	0.00017	excluded	K562	SF3B4
A5SS	JAK2	ENSG00000096968.8	chr9	+	5054562	5054884			5054562	5054789	5055668	5055788	-0.71000	0.00000	0.00000	shorter	K562	SRSF1
A5SS	JAK2	ENSG00000096968.8	chr9	+	5054562	5054884			5054562	5054789	5055668	5055788	-0.21000	0.00005	0.03183	shorter	K562	CPSF6
SE	JAK2	ENSG00000096968.8	chr9	+	4985939	4986022			4985244	4985630	5021962	5022213	-0.30400	0.00025	0.00539	excluded	K562	PUS1
MXE	JAK2	ENSG00000096968.8	chr9	+	4985939	4986022	5021962	5022213	4985244	4985630	5029782	5029906	0.13600	0.00243	0.04078	1included	K562	HNRNPC
SE	JAK2	ENSG00000096968.8	chr9	+	5090738	5090911			5090445	5090570	5123003	5123121	-0.05300	0.00281	0.04752	excluded	K562	SF3B4
A5SS	JAK2	ENSG00000096968.8	chr9	+	5054562	5054884			5054562	5054789	5055668	5055788	-0.13900	0.00318	0.09720	shorter	K562	PUS1
SE	JAK2	ENSG00000096968.8	chr9	+	5056540	5056606			5055668	5055788	5064882	5065040	0.08400	0.00358	0.05823	included	K562	SRSF1

Showing 1 to 8 of 8 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

JAK2

General Information

Functions

Localization

Domains (AlphaFold: JAK2)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for JAK2 is not avaliable on ENCORE database.

29 proteins are bound to JAK2 RNA:

eCLIP assay for JAK2 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for JAK2 is not available on ENCORE database.

91 RBPs can affect the gene expression of JAK2 :

The Knockdown/knockout RNA-Seq assay for JAK2 is not available on ENCORE database.

5 RBPs can affect the splicing of JAK2 :

The Knockdown/knockout RNA-Seq assay for JAK2 is not avaliable on ENCORE database.