DBNL

General Information

Gene Name : DBNL
Gene ID : ENSG00000136279.20
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: DBNL)

Not Available

Antibody Validation

Bethyl Labs: A303-351A

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	DBNL	ENSG00000136279.20	19.07	53.17	36.12	ENCSR000AEF
HepG2	DBNL	ENSG00000136279.20	38.46	13.87	26.16	ENCSR985KAT
K562	DBNL	ENSG00000136279.20	42.05	35.04	38.55	ENCSR000AEO

Assays

2 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Linked Antibody	Controls	Method	Note
knockdown followed by RNA-seq	DBNL-BGKcLV28-K562	ENCSR593NFA	DBNL	K562	Released		ENCSR220DTX	CRISPR	KD% = 57.4,57.6
knockdown followed by RNA-seq	DBNL-BGHcLV29-HepG2	ENCSR256UIA	DBNL	HepG2	Released		ENCSR462MFN	CRISPR	KD% = 64.8,64.0

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
DBNL	ENCAB188XWI	A303-351A	1					BGKcLV28-59, Released, ENCODE4

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project	Note
DBNL	K562	CRISPR	ENCSR593NFA	ENCSR220DTX	DBNL-BGKcLV28-59,DBNL-BGKcLV28-60	NT-BGKcLV28-1,NT-BGKcLV28-2	57.4,57.6	Released	ENCODE4
DBNL	HepG2	CRISPR	ENCSR256UIA	ENCSR462MFN	DBNL-BGHcLV29-59,DBNL-BGHcLV29-60	NT-BGHcLV29-1,NT-BGHcLV29-2	64.8,64.0	Released	ENCODE4

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
DBNL	Product_ID: A303-351A Lot_ID: 1 Source: Bethyl Labs Target Name: DBNL-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for DBNL is not avaliable on ENCORE database.

Proteins bound to RNA

DBNL RNA is bound by 20 proteins.

CanvasJS.com

eCLIP assay for DBNL is not avaliable on ENCORE database.

20 proteins are bound to DBNL RNA:

Show entries

Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr7	44097721	44097829	+	3'-UTR,CDS,intron-Proximal	3.58786	13.60410	HepG2	PPIG
chr7	44084465	44084545	+	intron-Distal,intron-Proximal	4.76667	12.65415	HepG2	SUGP2
chr7	44089912	44089999	+	intron-Distal,intron-Proximal	4.72268	12.29596	HepG2	EFTUD2
chr7	44086942	44087008	+	intron-Distal	5.28598	10.82239	HepG2	SUGP2
chr7	44100766	44100841	+	3'-UTR	5.39873	10.50616	HepG2	UPF1
chr7	44097829	44097880	+	3'-UTR,CDS,intron-Proximal	4.16068	8.40792	HepG2	PPIG
chr7	44085906	44085982	+	intron-Distal	3.45925	8.33119	HepG2	MATR3
chr7	44100889	44100982	+	3'-UTR	3.33953	8.16191	K562	UPF1
chr7	44100982	44101144	+	3'-UTR	3.46349	8.16191	K562	UPF1
chr7	44099140	44099173	+	3'-UTR,CDS,intron-Proximal	5.05112	7.65840	HepG2	PPIG
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 56 entries

eCLIP assay for DBNL is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for DBNL is not available on ENCORE database.
111 RBPs can affect the levels of DBNL.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for DBNL is not available on ENCORE database.

111 RBPs can affect the gene expression of DBNL :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
DBNL	ENSG00000136279.14	1440.22160	689.79430	1.06200	19.02950	17.66750	HepG2	BOP1
DBNL	ENSG00000136279.14	419.84710	920.98580	-1.13330	15.67080	14.12550	HepG2	U2AF1
DBNL	ENSG00000136279.14	675.84060	1101.53630	-0.70480	15.06800	13.77450	HepG2	CKAP4
DBNL	ENSG00000136279.14	634.36620	1257.42310	-0.98710	14.40640	13.21320	K562	AQR
DBNL	ENSG00000136279.14	1553.28800	792.22670	0.97120	13.78420	12.52890	HepG2	EIF2S1
DBNL	ENSG00000136279.14	973.13960	562.92860	0.78960	12.06320	11.14760	HepG2	TIAL1
DBNL	ENSG00000136279.14	1078.07930	583.20870	0.88630	12.20600	10.83980	HepG2	HNRNPC
DBNL	ENSG00000136279.14	395.34480	749.92700	-0.92360	11.68890	10.22120	K562	AKAP8L
DBNL	ENSG00000136279.14	64.31050	188.47940	-1.55130	11.42430	9.78140	K562	U2AF2
DBNL	ENSG00000136279.14	55.80240	188.27190	-1.75440	10.99910	9.40090	K562	G3BP2
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 126 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for DBNL is not available on ENCORE database.

17 RBPs can affect the splicing of DBNL :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
RI	DBNL	ENSG00000136279.14	chr7	+	44097380	44097879			44097380	44097458	44097727	44097879	-0.20300	0.00008	0.00997	excluded	K562	SBDS
RI	DBNL	ENSG00000136279.14	chr7	+	44097380	44097879			44097380	44097458	44097727	44097879	0.27200	0.00016	0.01525	included	HepG2	SUPV3L1
MXE	DBNL	ENSG00000136279.14	chr7	+	44092465	44092540	44096355	44096502	44091428	44091541	44097380	44097458	0.21200	0.00024	0.03453	1included	HepG2	HLTF
MXE	DBNL	ENSG00000136279.14	chr7	+	44092465	44092540	44096355	44096502	44091428	44091541	44097380	44097458	0.19900	0.00030	0.01389	1included	K562	XRN2
MXE	DBNL	ENSG00000136279.14	chr7	+	44092465	44092540	44096355	44096502	44091428	44091541	44097380	44097458	0.19600	0.00034	0.03246	1included	K562	NONO
MXE	DBNL	ENSG00000136279.14	chr7	+	44091428	44091541	44092465	44092540	44089823	44089879	44096355	44096502	-0.24200	0.00046	0.07642	2included	HepG2	DKC1
MXE	DBNL	ENSG00000136279.14	chr7	+	44092465	44092540	44096355	44096502	44091428	44091541	44097380	44097458	0.20400	0.00048	0.01839	1included	K562	UCHL5
MXE	DBNL	ENSG00000136279.14	chr7	+	44089823	44089879	44096355	44096502	44084300	44084419	44097380	44097458	0.29700	0.00055	0.02112	1included	K562	EFTUD2
MXE	DBNL	ENSG00000136279.14	chr7	+	44092465	44092540	44096355	44096502	44091428	44091541	44097380	44097458	0.23300	0.00090	0.02244	1included	K562	SUPV3L1
RI	DBNL	ENSG00000136279.14	chr7	+	44097380	44097879			44097380	44097458	44097727	44097879	0.11200	0.00135	0.01597	included	HepG2	RBM22

Showing 1 to 10 of 19 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

DBNL

General Information

Functions

Localization

Domains (AlphaFold: DBNL)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for DBNL is not avaliable on ENCORE database.

20 proteins are bound to DBNL RNA:

eCLIP assay for DBNL is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for DBNL is not available on ENCORE database.

111 RBPs can affect the gene expression of DBNL :

The Knockdown/knockout RNA-Seq assay for DBNL is not available on ENCORE database.

17 RBPs can affect the splicing of DBNL :

The Knockdown/knockout RNA-Seq assay for DBNL is not avaliable on ENCORE database.