RNASEH2A

General Information

Gene Name : RNASEH2A
Gene ID : ENSG00000104889.6
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: RNASEH2A)

Not Available

Antibody Validation

Bethyl Labs: A304-149A

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	RNASEH2A	ENSG00000104889.6	6.58	20.86	13.72	ENCSR000AEF
HepG2	RNASEH2A	ENSG00000104889.6	52.24	33.01	42.62	ENCSR985KAT
K562	RNASEH2A	ENSG00000104889.6	53.87	31.53	42.70	ENCSR000AEO

Assays

2 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Linked Antibody	Controls	Method	Note
knockdown followed by RNA-seq	RNASEH2A-BGKcLV30-K562	ENCSR002JOW	RNASEH2A	K562	Released		ENCSR347NKX	CRISPR	KD% = 68.3,66.9
knockdown followed by RNA-seq	RNASEH2A-BGHcLV32-HepG2	ENCSR703FPC	RNASEH2A	HepG2	Released		ENCSR232ERY	CRISPR	KD% = 93.8,94.7

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
RNASEH2A	ENCAB029VMC	A304-149A	1			Released, ENCODE4	BGHcLV32-35, Released, ENCODE4	BGKcLV30-37, Released, ENCODE4

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project	Note
RNASEH2A	K562	CRISPR	ENCSR002JOW	ENCSR347NKX	RNASEH2A-BGKcLV30-37,RNASEH2A-BGKcLV30-38	NT-BGKcLV30-1,NT-BGKcLV30-2	68.3,66.9	Released	ENCODE4
RNASEH2A	HepG2	CRISPR	ENCSR703FPC	ENCSR232ERY	RNASEH2A-BGHcLV32-35,RNASEH2A-BGHcLV32-36	NT-BGHcLV32-1,NT-BGHcLV32-2	93.8,94.7	Released	ENCODE4

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
RNASEH2A	Product_ID: A304-149A Lot_ID: 1 Source: Bethyl Labs Target Name: RNASEH2A-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for RNASEH2A is not avaliable on ENCORE database.

Proteins bound to RNA

RNASEH2A RNA is bound by 6 proteins.

CanvasJS.com

eCLIP assay for RNASEH2A is not avaliable on ENCORE database.

6 proteins are bound to RNASEH2A RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr19	12917448	12917512	+	5'-UTR,CDS	4.60706	16.20885	K562	DDX3X
chr19	12924236	12924293	+	3'-UTR,CDS	4.91041	10.44987	K562	PABPC4
chr19	12918232	12918272	+	CDS,intron-Proximal	3.52586	8.63185	K562	YBX3
chr19	12917577	12917614	+	CDS	4.10291	7.63469	K562	DDX3X
chr19	12917510	12917616	+	CDS,intron-Proximal	4.58150	6.15796	HepG2	DDX3X
chr19	12917405	12917448	+	5'-UTR	4.67973	5.07098	K562	DDX3X
chr19	12917932	12918050	+	CDS,intron-Proximal	3.99324	5.00154	HepG2	AQR
chr19	12918137	12918180	+	CDS,intron-Proximal	3.90399	4.75655	HepG2	PRPF8
chr19	12924141	12924176	+	CDS,intron-Proximal	4.26729	3.83925	K562	YBX3
chr19	12924229	12924282	+	3'-UTR,CDS	4.21422	3.72779	HepG2	LARP4
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 10 entries

eCLIP assay for RNASEH2A is not avaliable on ENCORE database.

Summary
DE Affected by

Diffrential Expression

The Knockdown/knockout assay for RNASEH2A is not available on ENCORE database.
105 RBPs can affect the levels of RNASEH2A.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for RNASEH2A is not available on ENCORE database.

105 RBPs can affect the gene expression of RNASEH2A :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
RNASEH2A	ENSG00000104889.4	157.75830	709.63100	-2.16940	58.50840	56.97390	HepG2	SRFBP1
RNASEH2A	ENSG00000104889.4	79.96830	386.68150	-2.27360	41.14280	39.67770	HepG2	ZNF622
RNASEH2A	ENSG00000104889.4	256.96040	751.72430	-1.54870	35.80120	34.08100	HepG2	ETF1
RNASEH2A	ENSG00000104889.4	82.31200	387.02190	-2.23320	26.03720	24.35110	HepG2	SUPV3L1
RNASEH2A	ENSG00000104889.4	50.83080	296.57740	-2.54460	25.98730	24.06220	HepG2	RRP9
RNASEH2A	ENSG00000104889.4	152.54960	458.24100	-1.58680	23.99000	22.46710	HepG2	CKAP4
RNASEH2A	ENSG00000104889.4	286.30640	654.71650	-1.19330	22.07350	20.47780	HepG2	AUH
RNASEH2A	ENSG00000104889.4	71.30290	299.82430	-2.07210	20.67400	18.77230	HepG2	PRPF8
RNASEH2A	ENSG00000104889.4	122.02340	351.59170	-1.52670	20.22740	18.68090	HepG2	UPF1
RNASEH2A	ENSG00000104889.4	122.19600	382.47730	-1.64620	18.89470	17.42620	HepG2	RPLP0
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 125 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

RNASEH2A

General Information

Functions

Localization

Domains (AlphaFold: RNASEH2A)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for RNASEH2A is not avaliable on ENCORE database.

6 proteins are bound to RNASEH2A RNA:

eCLIP assay for RNASEH2A is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for RNASEH2A is not available on ENCORE database.

105 RBPs can affect the gene expression of RNASEH2A :

The Knockdown/knockout RNA-Seq assay for RNASEH2A is not available on ENCORE database.

No RBPs affect the alternative splcing events of RNASEH2A on ENCORE database.

The Knockdown/knockout RNA-Seq assay for RNASEH2A is not avaliable on ENCORE database.