PSMA1

General Information

Gene Name : PSMA1
Gene ID : ENSG00000129084.17
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: PSMA1)

Not Available

Antibody Validation

Thermo Fisher: PA1-963

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	PSMA1	ENSG00000129084.17	176.58	140.61	158.60	ENCSR000AEF
HepG2	PSMA1	ENSG00000129084.17	132.82	209.51	171.16	ENCSR985KAT
K562	PSMA1	ENSG00000129084.17	183.44	190.54	186.99	ENCSR000AEO

Assays

2 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Linked Antibody	Controls	Method	Note
knockdown followed by RNA-seq	PSMA1-BGKcLV13-K562	ENCSR058MCC	PSMA1	K562	Released		ENCSR712CQC	CRISPR	KD% = 62.3,67.4
knockdown followed by RNA-seq	PSMA1-BGHcLV25-HepG2	ENCSR608CUI	PSMA1	HepG2	Released		ENCSR953VMB	CRISPR	KD% = 84.9,80.8

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
PSMA1	ENCAB320WSD	PA1-963	SD247982			Released, ENCODE4	BGHcLV25-51, Released, ENCODE4	BGKcLV13-61, Released, ENCODE4

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project
PSMA1	K562	CRISPR			BGKcLV13-59,BGKcLV13-60	BGKcLV13-1,BGKcLV13-2	0.0,0.0	NotSatisfied	ENCODE4
PSMA1	K562	CRISPR	ENCSR058MCC	ENCSR712CQC	PSMA1-BGKcLV13-61,PSMA1-BGKcLV13-62	NT-BGKcLV13-1,NT-BGKcLV13-2	62.3,67.4	Released	ENCODE4
PSMA1	HepG2	CRISPR			BGHcLV14-59,BGHcLV14-60	BGHcLV14-1,BGHcLV14-2	24.2,26.2	NotSatisfied	ENCODE4
PSMA1	HepG2	CRISPR			BGHcLV14-61,BGHcLV14-62	BGHcLV14-1,BGHcLV14-2	42.5,42.1	NotSatisfied	ENCODE4
PSMA1	HepG2	CRISPR			BGHcLV20-21,BGHcLV20-22	BGHcLV20-1,BGHcLV20-2	0.0,0.0	NotSatisfied	ENCODE4
PSMA1	HepG2	CRISPR			BGHcLV20-23,BGHcLV20-24	BGHcLV20-1,BGHcLV20-2	0.0,0.0	NotSatisfied	ENCODE4
PSMA1	HepG2	CRISPR			BGHcLV25-49,BGHcLV25-50	BGHcLV25-1,BGHcLV25-2	76.9,82.8	NotSatisfied	ENCODE4
PSMA1	HepG2	CRISPR	ENCSR608CUI	ENCSR953VMB	PSMA1-BGHcLV25-51,PSMA1-BGHcLV25-52	NT-BGHcLV25-1,NT-BGHcLV25-2	84.9,80.8	Released	ENCODE4

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
PSMA1	Product_ID: PA1-963 Lot_ID: SD247982 Source: Thermo Fisher Target Name: PSMA1-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for PSMA1 is not avaliable on ENCORE database.

Proteins bound to RNA

PSMA1 RNA is bound by 58 proteins.

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eCLIP assay for PSMA1 is not avaliable on ENCORE database.

58 proteins are bound to PSMA1 RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr11	14526663	14526711	-	3'-UTR,intron-Distal,intron-Proximal	5.69307	400.00000	K562	PABPC4
chr11	14526635	14526663	-	3'-UTR,intron-Distal,intron-Proximal	4.84861	78.55131	K562	PABPC4
chr11	14526602	14526635	-	3'-UTR,intron-Distal,intron-Proximal	5.24798	78.18407	K562	PABPC4
chr11	14521059	14521130	-	intron-Distal	7.87385	58.46593	K562	GTF2F1
chr11	14520486	14520563	-	3'-UTR,5'-UTR,intron-Distal,intron-Proximal	6.18872	48.61699	K562	SF3B4
chr11	14526552	14526633	-	3'-UTR,intron-Distal,intron-Proximal	6.04696	47.89756	HepG2	SUB1
chr11	14526425	14526495	-	3'-UTR,intron-Distal,intron-Proximal	8.07224	42.36078	HepG2	SUB1
chr11	14521065	14521138	-	intron-Distal	5.70660	40.80239	HepG2	PRPF4
chr11	14526462	14526495	-	3'-UTR,intron-Distal,intron-Proximal	4.52629	33.97737	K562	PABPC4
chr11	14521293	14521389	-	5'-UTR,intron-Distal,intron-Proximal	4.50468	32.60350	K562	DDX3X
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 182 entries

eCLIP assay for PSMA1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for PSMA1 is not available on ENCORE database.
93 RBPs can affect the levels of PSMA1.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for PSMA1 is not available on ENCORE database.

93 RBPs can affect the gene expression of PSMA1 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
PSMA1	ENSG00000129084.13	2616.32790	7472.64490	-1.51410	63.01960	59.63110	K562	GRSF1
PSMA1	ENSG00000129084.13	4050.23960	2143.86620	0.91770	54.46610	52.83700	HepG2	ZNF622
PSMA1	ENSG00000129084.13	2240.41100	4229.73080	-0.91680	43.14230	40.67130	K562	MTPAP
PSMA1	ENSG00000129084.13	657.43730	1616.78190	-1.29820	27.40260	25.44960	HepG2	SF3B1
PSMA1	ENSG00000129084.13	1381.16710	2187.97290	-0.66370	19.52200	18.02790	HepG2	SAFB2
PSMA1	ENSG00000129084.13	2089.35330	3737.16000	-0.83890	19.23680	17.74090	K562	HNRNPC
PSMA1	ENSG00000129084.13	2185.50120	3380.67210	-0.62930	17.50200	16.36540	HepG2	NELFE
PSMA1	ENSG00000129084.13	2070.76290	3037.78160	-0.55290	12.80300	11.79820	HepG2	PTBP1
PSMA1	ENSG00000129084.13	2188.91970	3148.79470	-0.52460	12.75740	11.57890	HepG2	RECQL
PSMA1	ENSG00000129084.13	3601.20820	4983.01310	-0.46850	12.90600	11.49350	K562	UPF1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 110 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for PSMA1 is not available on ENCORE database.

25 RBPs can affect the splicing of PSMA1 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	FDR	is_included	Cell Line	Affected by RBP
A3SS	PSMA1	ENSG00000129084.13	chr11	-	14535362	14535479	14535362	14535433	14535948	14536037	0.16600	0.00000	longer	HepG2	SF3A3
A3SS	PSMA1	ENSG00000129084.13	chr11	-	14535362	14535525	14535362	14535433	14535948	14536037	0.05800	0.00000	longer	K562	AQR
RI	PSMA1	ENSG00000129084.13	chr11	-	14535362	14536037	14535362	14535433	14535948	14536037	0.07200	0.00000	included	K562	SF3B4
RI	PSMA1	ENSG00000129084.13	chr11	-	14535362	14536037	14535362	14535433	14535948	14536037	-0.08800	0.00000	excluded	K562	DROSHA
RI	PSMA1	ENSG00000129084.13	chr11	-	14535362	14536037	14535362	14535433	14535948	14536037	0.17700	0.00000	included	HepG2	SF3A3
RI	PSMA1	ENSG00000129084.13	chr11	-	14535362	14536037	14535362	14535433	14535948	14536037	-0.06400	0.00004	excluded	K562	HNRNPUL1
RI	PSMA1	ENSG00000129084.13	chr11	-	14535362	14536037	14535362	14535433	14535948	14536037	0.21600	0.00000	included	HepG2	GRSF1
RI	PSMA1	ENSG00000129084.13	chr11	-	14535362	14536037	14535362	14535433	14535948	14536037	0.08800	0.00097	included	HepG2	DKC1
RI	PSMA1	ENSG00000129084.13	chr11	-	14535362	14536037	14535362	14535433	14535948	14536037	0.06800	0.00018	included	HepG2	IGF2BP3
RI	PSMA1	ENSG00000129084.13	chr11	-	14535362	14536037	14535362	14535433	14535948	14536037	0.09300	0.00000	included	HepG2	SRSF1

Showing 1 to 10 of 32 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

PSMA1

General Information

Functions

Localization

Domains (AlphaFold: PSMA1)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for PSMA1 is not avaliable on ENCORE database.

58 proteins are bound to PSMA1 RNA:

eCLIP assay for PSMA1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for PSMA1 is not available on ENCORE database.

93 RBPs can affect the gene expression of PSMA1 :

The Knockdown/knockout RNA-Seq assay for PSMA1 is not available on ENCORE database.

25 RBPs can affect the splicing of PSMA1 :

The Knockdown/knockout RNA-Seq assay for PSMA1 is not avaliable on ENCORE database.