CD3EAP

General Information

Gene Name : CD3EAP
Gene ID : ENSG00000117877.10
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: CD3EAP)

Not Available

Antibody Validation

View validation images for all CD3EAP antibodies

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	CD3EAP	ENSG00000117877.10	8.41	15.05	11.73	ENCSR000AEF
HepG2	CD3EAP	ENSG00000117877.10	23.58	20.52	22.05	ENCSR985KAT
K562	CD3EAP	ENSG00000117877.10	23.53	25.14	24.34	ENCSR000AEO

Assays

3 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Controls	Method	Note
knockdown followed by RNA-seq	CD3EAP-BGKcLV15-K562	ENCSR443BEF	CD3EAP	K562	Released	ENCSR404OHQ	CRISPR	KD% = 51.4,66.4
knockdown followed by RNA-seq	CD3EAP-BGKcLV28-K562	ENCSR323SDL	CD3EAP	K562	Released	ENCSR220DTX	CRISPR	KD% = 60.2,64.5
knockdown followed by RNA-seq	CD3EAP-BGHcLV16-HepG2	ENCSR400XYB	CD3EAP	HepG2	Released	ENCSR964HKT	CRISPR	KD% = 52.9,52.4

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
CD3EAP	ENCAB088EWX	PA5-27632	TL2692990			NotSatisfied, ENCODE4	BGHcLV16-11, Released, ENCODE4	BGKcLV15-9, Released, ENCODE4
CD3EAP	ENCAB469OLR	A301-294A	2			Released, ENCODE4	BGHcLV16-11, Released, ENCODE4	BGKcLV28-9, Released, ENCODE4

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project
CD3EAP	K562	CRISPR	ENCSR443BEF	ENCSR404OHQ	CD3EAP-BGKcLV15-9,CD3EAP-BGKcLV15-10	NT-BGKcLV15-1,NT-BGKcLV15-2	51.4,66.4	Released	ENCODE4
CD3EAP	K562	CRISPR	ENCSR323SDL	ENCSR220DTX	CD3EAP-BGKcLV28-9,CD3EAP-BGKcLV28-10	NT-BGKcLV28-1,NT-BGKcLV28-2	60.2,64.5	Released	ENCODE4
CD3EAP	HepG2	CRISPR	ENCSR400XYB	ENCSR964HKT	CD3EAP-BGHcLV16-11,CD3EAP-BGHcLV16-12	NT-BGHcLV16-1,NT-BGHcLV16-2	52.9,52.4	Released	ENCODE4
CD3EAP	HepG2	CRISPR			BGHcLV27-59,BGHcLV27-60	BGHcLV27-1,BGHcLV27-2	13.0,17.0	NotSatisfied	ENCODE4

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
CD3EAP	Product_ID: PA5-27632 Lot_ID: TL2692990 Source: Thermo Fisher Target Name: CD3EAP-human
CD3EAP	Product_ID: A301-294A Lot_ID: 2 Source: Bethyl Labs Target Name: CD3EAP-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for CD3EAP is not avaliable on ENCORE database.

Proteins bound to RNA

CD3EAP RNA is bound by 8 proteins.

CanvasJS.com

eCLIP assay for CD3EAP is not avaliable on ENCORE database.

8 proteins are bound to CD3EAP RNA:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr19	45912910	45912992	+	3'-UTR	4.04105	5.53799	K562	FAM120A
chr19	45912640	45912764	+	3'-UTR,CDS	4.84455	4.78571	K562	UCHL5
chr19	45913333	45913403	+	3'-UTR	3.70634	4.50550	K562	UPF1
chr19	45913459	45913495	+	3'-UTR	4.28645	3.20319	K562	UPF1
chr19	45911397	45911531	+	3'-UTR,CDS	4.45776	4.23295	HepG2	GRWD1
chr19	45913833	45913910	+	3'-UTR	3.61295	6.37005	K562	UPF1
chr19	45913840	45913928	+	3'-UTR	4.83130	6.42251	K562	FAM120A
chr19	45913844	45913943	+	3'-UTR	3.47267	6.21080	HepG2	PCBP2
chr19	45909976	45910101	+	5'-UTR,CDS,intron-Distal,intron-Proximal	4.46454	6.77156	K562	AQR
chr19	45912273	45912342	+	CDS	4.80554	5.86954	K562	UCHL5
chr19	45912433	45912490	+	CDS	3.29478	3.73423	K562	UCHL5
chr19	45912215	45912273	+	CDS	4.64458	5.86954	K562	UCHL5
chr19	45912032	45912100	+	CDS	3.62152	5.49349	K562	ZNF800
chr19	45912018	45912087	+	CDS	3.32762	5.07480	K562	PUM1
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

eCLIP assay for CD3EAP is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for CD3EAP is not available on ENCORE database.
102 RBPs can affect the levels of CD3EAP.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for CD3EAP is not available on ENCORE database.

102 RBPs can affect the gene expression of CD3EAP :

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
CD3EAP	ENSG00000117877.6	414.80630	287.28510	0.52990	2.46340	1.95880	HepG2	AKAP1
CD3EAP	ENSG00000117877.6	297.19760	510.76340	-0.78120	9.31520	8.17880	HepG2	AUH
CD3EAP	ENSG00000117877.6	124.66260	293.53530	-1.23550	8.48500	7.02330	HepG2	BCLAF1
CD3EAP	ENSG00000117877.6	336.99750	621.10540	-0.88210	9.29040	8.27530	HepG2	BOP1
CD3EAP	ENSG00000117877.6	273.07450	506.98410	-0.89260	6.36770	4.86660	HepG2	CCAR1
CD3EAP	ENSG00000117877.6	138.30240	225.83360	-0.70740	3.14410	2.32170	HepG2	CIRBP
CD3EAP	ENSG00000117877.6	246.55790	570.19490	-1.20950	13.80370	12.40650	HepG2	CPSF6
CD3EAP	ENSG00000117877.6	467.61550	347.21800	0.42940	2.97570	2.31270	HepG2	CELF1
CD3EAP	ENSG00000117877.6	259.70450	373.37870	-0.52380	4.23020	3.34400	HepG2	DAZAP1
CD3EAP	ENSG00000117877.6	124.61850	206.09280	-0.72580	3.45610	2.70510	HepG2	DDX21
CD3EAP	ENSG00000117877.6	142.36850	275.19090	-0.95080	5.65050	4.78630	HepG2	DDX3X
CD3EAP	ENSG00000117877.6	343.21670	647.50270	-0.91580	5.41740	4.06320	HepG2	DDX59
CD3EAP	ENSG00000117877.6	247.09640	342.02700	-0.46900	2.38800	1.44600	HepG2	DDX5
CD3EAP	ENSG00000117877.6	136.70910	236.41010	-0.79020	3.54340	2.85240	HepG2	DDX6
CD3EAP	ENSG00000117877.6	122.17660	210.14350	-0.78240	4.02040	2.85250	HepG2	DHX30
CD3EAP	ENSG00000117877.6	172.14820	278.13660	-0.69210	4.39720	3.57950	HepG2	DKC1
CD3EAP	ENSG00000117877.6	137.07800	217.87290	-0.66850	3.51570	2.73000	HepG2	DNAJC21
CD3EAP	ENSG00000117877.6	77.26840	227.25140	-1.55630	10.59690	9.48350	HepG2	EIF2S1
CD3EAP	ENSG00000117877.6	435.96970	310.76030	0.48830	3.01280	1.78560	HepG2	EIF2S2
CD3EAP	ENSG00000117877.6	179.82700	251.13210	-0.48180	1.83810	1.31300	HepG2	EIF4A3
CD3EAP	ENSG00000117877.6	383.20570	244.52650	0.64800	3.00870	2.29410	HepG2	EIF4B
CD3EAP	ENSG00000117877.6	228.93950	352.84340	-0.62410	3.83980	2.89130	HepG2	EIF4G2
CD3EAP	ENSG00000117877.6	458.46740	586.44910	-0.35520	2.74460	2.14600	HepG2	ETF1
CD3EAP	ENSG00000117877.6	433.25580	284.05300	0.60900	4.49620	3.43770	HepG2	EWSR1
CD3EAP	ENSG00000117877.6	330.60150	571.20070	-0.78890	2.93770	1.88990	HepG2	FTO
CD3EAP	ENSG00000117877.6	253.85780	646.32290	-1.34820	15.87950	14.46600	HepG2	GPKOW
CD3EAP	ENSG00000117877.6	122.00280	219.96040	-0.85030	4.08590	3.32390	HepG2	HNRNPA1
CD3EAP	ENSG00000117877.6	234.34840	343.12930	-0.55010	3.79770	2.73060	HepG2	HNRNPA2B1
CD3EAP	ENSG00000117877.6	123.76600	244.67270	-0.98320	5.62900	4.66700	HepG2	HNRNPC
CD3EAP	ENSG00000117877.6	346.44640	620.64180	-0.84110	11.44560	10.12160	HepG2	HNRNPF
CD3EAP	ENSG00000117877.6	363.77960	238.04480	0.61170	3.42530	2.65100	HepG2	HNRNPK
CD3EAP	ENSG00000117877.6	181.55570	616.80120	-1.76440	25.86620	24.26350	HepG2	HNRNPLL
CD3EAP	ENSG00000117877.6	275.89930	611.16000	-1.14740	16.12290	14.53340	HepG2	IGF2BP1
CD3EAP	ENSG00000117877.6	486.97070	254.90790	0.93380	7.08130	6.10730	HepG2	MATR3
CD3EAP	ENSG00000117877.6	239.39290	629.13900	-1.39400	12.71520	10.61910	HepG2	MTPAP
CD3EAP	ENSG00000117877.6	259.03510	546.93950	-1.07820	10.91070	9.51000	HepG2	NSUN2
CD3EAP	ENSG00000117877.6	181.19730	112.72980	0.68460	2.17770	1.40440	HepG2	PABPC1
CD3EAP	ENSG00000117877.6	335.93190	209.17370	0.68340	5.32740	4.52910	HepG2	PCBP1
CD3EAP	ENSG00000117877.6	178.78650	272.61770	-0.60860	2.52080	1.52970	HepG2	PCBP2
CD3EAP	ENSG00000117877.6	197.15660	110.60210	0.83390	3.40150	1.70600	HepG2	PNPT1
CD3EAP	ENSG00000117877.6	118.38160	256.21760	-1.11390	6.79010	5.58710	HepG2	PRPF8
CD3EAP	ENSG00000117877.6	189.24630	353.41680	-0.90110	7.17780	6.27420	HepG2	PUF60
CD3EAP	ENSG00000117877.6	582.53370	375.15640	0.63470	7.72990	6.84250	HepG2	PUM1
CD3EAP	ENSG00000117877.6	180.49110	296.11920	-0.71430	5.47370	4.66040	HepG2	PUS1
CD3EAP	ENSG00000117877.6	139.75150	209.20490	-0.58210	2.47780	1.83570	HepG2	RBM25
CD3EAP	ENSG00000117877.6	408.44030	288.97460	0.49910	2.56550	1.61280	HepG2	RBM27
CD3EAP	ENSG00000117877.6	359.71680	668.50830	-0.89410	9.54130	8.39730	HepG2	RPLP0
CD3EAP	ENSG00000117877.6	133.32200	258.46600	-0.95510	4.84040	3.60680	HepG2	RPS10
CD3EAP	ENSG00000117877.6	201.48940	116.64870	0.78840	3.44400	1.99320	HepG2	SART3
CD3EAP	ENSG00000117877.6	380.75850	610.48970	-0.68110	5.76480	4.77710	HepG2	SF3B1
CD3EAP	ENSG00000117877.6	402.60860	252.40580	0.67350	4.70630	3.90420	HepG2	SMN1
CD3EAP	ENSG00000117877.6	299.22830	679.28460	-1.18280	9.89870	8.42660	HepG2	SNRNP70
CD3EAP	ENSG00000117877.6	359.62080	553.60620	-0.62240	6.78730	6.09930	HepG2	SRFBP1
CD3EAP	ENSG00000117877.6	452.40740	656.95060	-0.53820	3.08830	2.02270	HepG2	SRSF3
CD3EAP	ENSG00000117877.6	315.12650	609.74270	-0.95230	14.08030	12.71960	HepG2	SRSF7
CD3EAP	ENSG00000117877.6	177.54900	480.64560	-1.43680	23.86590	22.68830	HepG2	SSB
CD3EAP	ENSG00000117877.6	349.56390	238.01520	0.55440	2.89310	1.58160	HepG2	SSRP1
CD3EAP	ENSG00000117877.6	632.69140	396.84580	0.67280	8.53790	7.54600	HepG2	SUCLG1
CD3EAP	ENSG00000117877.6	87.91690	330.64570	-1.91110	17.53540	16.08620	HepG2	SUPV3L1
CD3EAP	ENSG00000117877.6	133.60620	207.90960	-0.63800	3.00350	2.42310	HepG2	TAF15
CD3EAP	ENSG00000117877.6	266.59060	601.28960	-1.17340	14.05650	12.62700	HepG2	TARDBP
CD3EAP	ENSG00000117877.6	123.19060	236.14520	-0.93880	6.14580	5.45350	HepG2	TIAL1
CD3EAP	ENSG00000117877.6	466.45070	353.85420	0.39850	1.96060	1.42200	HepG2	U2AF1
CD3EAP	ENSG00000117877.6	222.44620	358.30110	-0.68770	5.72270	4.77570	HepG2	UPF1
CD3EAP	ENSG00000117877.6	184.96200	302.76450	-0.71100	3.23560	2.14630	HepG2	UPF2
CD3EAP	ENSG00000117877.6	508.61140	345.92590	0.55600	5.06630	4.29680	HepG2	UTP3
CD3EAP	ENSG00000117877.6	223.65520	325.48450	-0.54130	2.45190	1.76540	HepG2	XRN2
CD3EAP	ENSG00000117877.6	196.31940	359.55890	-0.87300	4.93410	4.08080	HepG2	ZC3H8
CD3EAP	ENSG00000117877.6	253.07320	394.06290	-0.63890	5.95390	5.23120	HepG2	ZNF622
CD3EAP	ENSG00000117877.6	485.16240	818.96960	-0.75530	7.51100	6.04610	K562	BOP1
CD3EAP	ENSG00000117877.6	551.50620	870.82970	-0.65900	7.69790	6.37990	K562	CPSF6
CD3EAP	ENSG00000117877.6	1689.10600	1103.12350	0.61460	7.05290	6.07890	K562	DDX47
CD3EAP	ENSG00000117877.6	411.03900	267.00430	0.62230	4.93120	3.71050	K562	DKC1
CD3EAP	ENSG00000117877.6	609.31140	1189.55180	-0.96520	21.58040	19.86120	K562	EIF2S2
CD3EAP	ENSG00000117877.6	602.37380	427.19920	0.49570	2.18790	1.30590	K562	EIF3A
CD3EAP	ENSG00000117877.6	622.25730	259.15100	1.26360	21.26160	19.00290	K562	EIF3G
CD3EAP	ENSG00000117877.6	367.07550	223.77830	0.71390	5.12320	4.00530	K562	EIF4A3
CD3EAP	ENSG00000117877.6	292.91730	201.51930	0.53950	3.35890	2.06310	K562	EIF4B
CD3EAP	ENSG00000117877.6	163.72630	277.24610	-0.75990	4.33310	2.29000	K562	FASTKD2
CD3EAP	ENSG00000117877.6	717.18120	1100.40530	-0.61760	3.32240	2.38780	K562	FIP1L1
CD3EAP	ENSG00000117877.6	487.09830	885.99050	-0.86310	10.44100	8.72270	K562	FMR1
CD3EAP	ENSG00000117877.6	513.93550	750.93160	-0.54710	4.19370	3.04840	K562	FTO
CD3EAP	ENSG00000117877.6	307.15260	211.11170	0.54080	3.41020	1.40640	K562	FUBP3
CD3EAP	ENSG00000117877.6	119.79000	229.12710	-0.93560	4.52270	2.75880	K562	FUS
CD3EAP	ENSG00000117877.6	1034.63460	232.71910	2.15240	71.38710	68.61860	K562	FXR1
CD3EAP	ENSG00000117877.6	62.56180	136.92170	-1.13000	4.56700	3.60770	K562	G3BP2
CD3EAP	ENSG00000117877.6	497.81090	831.45210	-0.74000	7.88260	6.53500	K562	GPKOW
CD3EAP	ENSG00000117877.6	208.00370	415.91840	-0.99970	4.57570	2.88110	K562	HNRNPA2B1
CD3EAP	ENSG00000117877.6	251.84810	570.57440	-1.17990	14.78380	13.48740	K562	HNRNPC
CD3EAP	ENSG00000117877.6	1102.72810	1492.03400	-0.43620	2.24740	1.52650	K562	HSPD1
CD3EAP	ENSG00000117877.6	467.95670	709.89350	-0.60120	3.69860	2.60100	K562	KRR1
CD3EAP	ENSG00000117877.6	533.17500	249.76090	1.09400	14.18860	12.16760	K562	MAGOH
CD3EAP	ENSG00000117877.6	509.72180	249.24870	1.03200	12.58120	10.49280	K562	MATR3
CD3EAP	ENSG00000117877.6	614.81820	811.57990	-0.40060	2.21080	1.42780	K562	METAP2
CD3EAP	ENSG00000117877.6	761.36740	954.95540	-0.32680	2.28910	1.60430	K562	NSUN2
CD3EAP	ENSG00000117877.6	221.00450	363.92940	-0.71960	2.46760	1.54640	K562	PABPN1
CD3EAP	ENSG00000117877.6	379.55550	222.21870	0.77220	5.73110	4.31450	K562	PCBP2
CD3EAP	ENSG00000117877.6	625.98780	998.14210	-0.67310	6.24560	4.99270	K562	PCBP3
CD3EAP	ENSG00000117877.6	514.29790	759.22730	-0.56190	4.44260	2.38520	K562	PKM
CD3EAP	ENSG00000117877.6	608.45470	765.56500	-0.33140	2.37590	1.63470	K562	POLR2G
CD3EAP	ENSG00000117877.6	340.41980	511.56990	-0.58760	4.34000	3.16900	K562	PSIP1
CD3EAP	ENSG00000117877.6	764.89560	242.66100	1.65620	13.91950	12.49130	K562	PTBP1
CD3EAP	ENSG00000117877.6	1843.55250	1269.54160	0.53810	2.56770	1.78290	K562	PUF60
CD3EAP	ENSG00000117877.6	1866.60150	1349.56970	0.46780	2.25670	1.30360	K562	PUM1
CD3EAP	ENSG00000117877.6	344.87150	232.66320	0.56770	3.45920	2.51400	K562	RBM22
CD3EAP	ENSG00000117877.6	391.78850	244.84540	0.67810	3.71050	2.42430	K562	NELFE
CD3EAP	ENSG00000117877.6	1200.96850	682.27520	0.81570	3.19800	2.03470	K562	SAFB
CD3EAP	ENSG00000117877.6	596.52240	790.65300	-0.40650	2.32460	1.44180	K562	SF3B1
CD3EAP	ENSG00000117877.6	261.56250	142.38860	0.87720	6.37630	5.04130	K562	SF3B4
CD3EAP	ENSG00000117877.6	146.49860	237.95680	-0.69980	3.39350	1.60890	K562	SND1
CD3EAP	ENSG00000117877.6	370.94330	237.89280	0.64080	4.42070	3.53130	K562	SRSF1
CD3EAP	ENSG00000117877.6	197.01750	457.24220	-1.21460	5.95160	3.62940	K562	SUPT6H
CD3EAP	ENSG00000117877.6	1416.24700	767.94250	0.88290	17.09060	15.08310	K562	SYNCRIP
CD3EAP	ENSG00000117877.6	347.34530	240.75420	0.52870	2.90220	2.17740	K562	TARDBP
CD3EAP	ENSG00000117877.6	367.50380	492.05040	-0.42100	2.18150	1.36060	K562	TIAL1
CD3EAP	ENSG00000117877.6	889.70560	1446.94050	-0.70160	7.16810	5.09650	K562	TROVE2
CD3EAP	ENSG00000117877.6	356.09060	581.51070	-0.70760	5.67040	4.16070	K562	UCHL5
CD3EAP	ENSG00000117877.6	513.16530	1012.55170	-0.98050	10.01980	8.76250	K562	UPF1
CD3EAP	ENSG00000117877.6	447.00100	866.42110	-0.95480	4.49210	3.36390	K562	WDR3
CD3EAP	ENSG00000117877.6	198.27430	389.45030	-0.97390	4.04000	1.91410	K562	XPO5
CD3EAP	ENSG00000117877.6	234.12670	449.86580	-0.94220	3.92300	1.88680	K562	YTHDC2
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for CD3EAP is not available on ENCORE database.

1 RBPs can affect the splicing of CD3EAP :

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP	Bound by RBP
A5SS	CD3EAP	ENSG00000117877.6	chr19	+	45910351	45910578			45910351	45910493	45911390	45914024	0.17200	0.00004	0.00116	longer	K562	AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

CD3EAP

General Information

Functions

Localization

Domains (AlphaFold: CD3EAP)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for CD3EAP is not avaliable on ENCORE database.

8 proteins are bound to CD3EAP RNA:

eCLIP assay for CD3EAP is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for CD3EAP is not available on ENCORE database.

102 RBPs can affect the gene expression of CD3EAP :

The Knockdown/knockout RNA-Seq assay for CD3EAP is not available on ENCORE database.

1 RBPs can affect the splicing of CD3EAP :

The Knockdown/knockout RNA-Seq assay for CD3EAP is not avaliable on ENCORE database.