APTX

General Information

Gene Name : APTX
Gene ID : ENSG00000137074.18
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: APTX)

Not Available

Antibody Validation

Thermo Fisher: PA5-92422

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	APTX	ENSG00000137074.18	44.26	39.71	41.98	ENCSR000AEF
HepG2	APTX	ENSG00000137074.18	28.95	40.51	34.73	ENCSR985KAT
K562	APTX	ENSG00000137074.18	42.01	49.47	45.74	ENCSR000AEO

Assays

2 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Linked Antibody	Controls	Method	Note
knockdown followed by RNA-seq	APTX-BGKcLV23-K562	ENCSR148HLA	APTX	K562	Released		ENCSR877JEM	CRISPR	KD% = 71.0,78.0264144
knockdown followed by RNA-seq	APTX-BGHcLV24-HepG2	ENCSR489DNH	APTX	HepG2	Released		ENCSR671FDZ	CRISPR	KD% = 76.0,77.0

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
APTX	ENCAB069JSS	PA5-92422	UK2881303A			Released, ENCODE4	BGHcLV24-11, Released, ENCODE4	BGKcLV23-15, Released, ENCODE4

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project
APTX	K562	CRISPR	ENCSR148HLA	ENCSR877JEM	APTX-BGKcLV23-15,APTX-BGKcLV23-16	NT-BGKcLV23-1,NT-BGKcLV23-2	71.0,78.0264144	Released	ENCODE4
APTX	K562	CRISPR			BGKcLV23-17,BGKcLV23-18	BGKcLV23-1,BGKcLV23-2	61.0,62.7	NotSatisfied	ENCODE4
APTX	HepG2	CRISPR	ENCSR489DNH	ENCSR671FDZ	APTX-BGHcLV24-11,APTX-BGHcLV24-12	NT-BGHcLV24-1,NT-BGHcLV24-2	76.0,77.0	Released	ENCODE4
APTX	HepG2	CRISPR			BGHcLV24-13,BGHcLV24-14	BGHcLV24-1,BGHcLV24-2	71.0,74.0	NotSatisfied	ENCODE4

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
APTX	Product_ID: PA5-92422 Lot_ID: UK2881303A Source: Thermo Fisher Target Name: APTX-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for APTX is not avaliable on ENCORE database.

Proteins bound to RNA

APTX RNA is bound by 17 proteins.

CanvasJS.com

eCLIP assay for APTX is not avaliable on ENCORE database.

17 proteins are bound to APTX RNA:

Show entries

Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr9	32985972	32986036	-	3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal	4.20134	14.20290	HepG2	U2AF2
chr9	32985980	32986036	-	3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal	5.41083	13.76205	K562	U2AF2
chr9	32989825	32989894	-	3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal	3.32041	8.73886	K562	DDX3X
chr9	33018961	33019024	-	intron-Distal	5.36230	8.57494	HepG2	U2AF2
chr9	32999049	32999150	-	intron-Distal	4.99200	8.56566	HepG2	SUGP2
chr9	33024921	33025016	-	5'-UTR,intron-Distal,intron-Proximal	3.74336	7.64728	K562	AQR
chr9	32985986	32986035	-	3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal	5.15898	7.45412	K562	U2AF1
chr9	32999242	32999330	-	intron-Distal	3.87824	6.49112	K562	PTBP1
chr9	32992118	32992203	-	intron-Distal	4.73231	6.36848	HepG2	SUGP2
chr9	32997903	32998035	-	intron-Distal	4.61132	6.01663	K562	MATR3
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 40 entries

eCLIP assay for APTX is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for APTX is not available on ENCORE database.
57 RBPs can affect the levels of APTX.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for APTX is not available on ENCORE database.

57 RBPs can affect the gene expression of APTX :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
APTX	ENSG00000137074.14	881.36430	427.96370	1.04220	18.22270	17.14790	HepG2	TIAL1
APTX	ENSG00000137074.14	1189.63520	696.45890	0.77230	13.67950	12.70200	HepG2	RBM22
APTX	ENSG00000137074.14	1001.87810	682.96730	0.55270	8.35470	7.55710	HepG2	SSB
APTX	ENSG00000137074.14	194.47000	375.55150	-0.94950	7.41920	6.33610	HepG2	CPSF6
APTX	ENSG00000137074.14	773.59850	1109.07900	-0.51970	7.07930	6.00650	K562	EIF2S2
APTX	ENSG00000137074.14	991.18010	1512.60350	-0.60980	6.69080	5.84250	K562	AQR
APTX	ENSG00000137074.14	1205.97080	728.48680	0.72710	6.79620	5.84130	HepG2	MATR3
APTX	ENSG00000137074.14	630.27950	414.66080	0.60400	6.58480	5.72760	HepG2	UTP3
APTX	ENSG00000137074.14	384.35250	649.42580	-0.75670	6.40790	5.52620	HepG2	EIF2S1
APTX	ENSG00000137074.14	330.95300	540.35160	-0.70730	6.62450	5.40560	K562	CPSF6
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 63 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for APTX is not available on ENCORE database.

20 RBPs can affect the splicing of APTX :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	APTX	ENSG00000137074.14	chr9	-	32988080	32988127	32987541	32987844	32989756	32990086	-0.64700	0.00000	0.00000	excluded	K562	SF3B4
SE	APTX	ENSG00000137074.14	chr9	-	32988080	32988127	32987541	32987729	32989756	32990086	-0.29200	0.00000	0.00000	excluded	K562	AKAP8L
A3SS	APTX	ENSG00000137074.14	chr9	-	32987541	32987844	32987541	32987729	32988080	32988127	-0.27900	0.00000	0.00641	shorter	HepG2	DDX59
A3SS	APTX	ENSG00000137074.14	chr9	-	32989756	32989917	32989756	32989893	33024997	33025166	0.50500	0.00000	0.00000	longer	K562	AQR
SE	APTX	ENSG00000137074.14	chr9	-	32988080	32988127	32987541	32987729	32989756	32990086	-0.21200	0.00003	0.00078	excluded	K562	PUS1
A3SS	APTX	ENSG00000137074.14	chr9	-	32987541	32987844	32987541	32987729	32988080	32988127	-0.29600	0.00004	0.02543	shorter	HepG2	DDX6
SE	APTX	ENSG00000137074.14	chr9	-	32988080	32988127	32987541	32987844	32989756	32990086	-0.40900	0.00006	0.00482	excluded	HepG2	SF3B4
A3SS	APTX	ENSG00000137074.14	chr9	-	32988076	32988127	32988076	32988122	32989756	32990086	-0.40700	0.00007	0.05901	shorter	HepG2	RBM5
SE	APTX	ENSG00000137074.14	chr9	-	32988080	32988127	32987541	32987729	32989756	32990086	0.24100	0.00013	0.01827	included	HepG2	SUPV3L1
SE	APTX	ENSG00000137074.14	chr9	-	32988080	32988127	32987541	32987844	32989756	32989893	-0.31200	0.00014	0.00227	excluded	K562	AQR

Showing 1 to 10 of 32 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

APTX

General Information

Functions

Localization

Domains (AlphaFold: APTX)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for APTX is not avaliable on ENCORE database.

17 proteins are bound to APTX RNA:

eCLIP assay for APTX is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for APTX is not available on ENCORE database.

57 RBPs can affect the gene expression of APTX :

The Knockdown/knockout RNA-Seq assay for APTX is not available on ENCORE database.

20 RBPs can affect the splicing of APTX :

The Knockdown/knockout RNA-Seq assay for APTX is not avaliable on ENCORE database.