TNKS2

General Information

Gene Name       : TNKS2
Gene ID             : ENSG00000107854.5
Essential Gene : No

Functions

Localization

Domains (AlphaFold: TNKS2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TNKS2ENSG00000107854.58.798.368.57ENCSR000AEF
HepG2TNKS2ENSG00000107854.510.6317.2813.96ENCSR985KAT
K562TNKS2ENSG00000107854.59.319.469.39ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TNKS2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • TNKS2 RNA is bound by 20 proteins.  







eCLIP assay for TNKS2 is not avaliable on ENCORE database.





20 proteins are bound to TNKS2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr109362301293623095+3'-UTR3.374794.30679K562KHSRP
chr109362303393623145+3'-UTR8.04117102.32228K562QKI
chr109362479993624900+3'-UTR3.978217.37361HepG2RBFOX2
chr109362429693624336+3'-UTR3.609023.40672HepG2FUBP3
chr109362291893623014+3'-UTR4.426524.26925HepG2KHSRP
chr109362427793624363+3'-UTR5.3915923.60961K562PUM2
chr109362313493623199+3'-UTR4.666534.73972K562PUM2
chr109362308693623140+3'-UTR6.7601711.86079HepG2QKI
chr109362481693624880+3'-UTR4.378686.72824HepG2FUBP3
chr109362491093624974+3'-UTR3.538287.47525HepG2FUBP3
chr109362468093624877+3'-UTR3.778044.54121HepG2KHSRP
chr109362304993623086+3'-UTR5.990966.58335HepG2QKI
chr109355840193558447+5'-UTR5.2541111.01276HepG2DDX3X
chr109355834493558512+5'-UTR,CDS3.952234.21542HepG2SRSF1
chr109355835593558401+5'-UTR4.461249.66125HepG2DDX3X
chr109355821093558306+5'-UTR5.6877227.55644HepG2DDX3X
chr109355844993558525+CDS4.4137119.60986HepG2DDX3X
chr109357927993579310+CDS3.764967.23562HepG2BCLAF1
chr109357287893572965+CDS,intron-Proximal3.499723.93645HepG2PPIG
chr109357972093579791+CDS,intron-Proximal4.175184.72426K562LIN28B
chr109357918793579276+CDS,intron-Proximal4.650428.79198HepG2BUD13
chr109359376393593777+CDS3.156344.34695HepG2BCLAF1
chr109357902793579091+CDS,intron-Proximal4.561994.62947HepG2AQR
chr109357973793579781+CDS5.684379.78817HepG2BCLAF1
chr109359072893590758+CDS3.524295.11155K562YBX3
chr109360200293602144+CDS4.490545.00488K562LIN28B
chr109358806093588065+CDS3.650844.51739HepG2BCLAF1
chr109360037793600460+CDS3.4905313.76394HepG2BCLAF1
chr109357931193579359+CDS,intron-Proximal4.092934.98250K562AQR
chr109358210793582160+CDS,intron-Proximal4.508394.21433K562PRPF8
chr109357689093576926+CDS,intron-Proximal3.321419.03865HepG2BCLAF1
chr109359360693593689+CDS,intron-Proximal3.457163.75245K562BUD13
chr109360104493601097+CDS4.398138.15024HepG2BCLAF1
chr109360193293601950+CDS4.080345.79432HepG2BCLAF1
chr109360037593600459+CDS4.624044.21675K562ZNF622
chr109360199693602053+CDS3.834248.66838HepG2BCLAF1
chr109359091993590937+CDS3.477445.45876HepG2BCLAF1
chr109359067893590744+CDS,intron-Proximal3.6091310.26109HepG2BCLAF1
chr109360545893605546+CDS,intron-Proximal5.075184.90235K562SF3B4
chr109360205393602097+CDS3.938445.97823HepG2BCLAF1
chr109359366593593720+CDS3.080345.60276HepG2BCLAF1
chr109357924493579347+CDS,intron-Proximal4.640614.97857HepG2AQR
chr109359669793596724+CDS4.433526.22576HepG2BCLAF1
chr109360925193609314+CDS,intron-Proximal3.141895.79202HepG2U2AF2
chr109358199493582065+CDS,intron-Proximal5.022643.91589K562SF3B4
chr109357272993572776+CDS,intron-Proximal3.622363.55754HepG2U2AF2
chr109359072393590728+CDS4.124143.83925K562YBX3
chr109360032393600358+CDS3.482177.42278HepG2BCLAF1
chr109357971793579786+CDS4.368444.01886HepG2LIN28B
chr109360209793602137+CDS4.516407.53358HepG2BCLAF1
chr109361477293614829+CDS,intron-Proximal3.331863.80334HepG2U2AF2
chr109361718693617246+CDS4.2184012.50436HepG2BCLAF1
chr109362267793622717+CDS,intron-Proximal3.742864.36528HepG2U2AF2
chr109358202593582081+CDS,intron-Proximal4.114913.44423K562BUD13
chr109359372293593773+CDS4.144363.53690K562ZNF622
chr109358208693582155+CDS,intron-Proximal6.422738.04585HepG2PRPF8
chr109359082693590932+CDS,intron-Proximal4.393064.75425K562EFTUD2
chr109357970293579723+CDS3.007554.23325HepG2BCLAF1
chr109356496793565107+intron-Distal4.677686.34129HepG2HNRNPL
chr109360502293605081+intron-Distal4.185104.58794K562KHSRP
chr109360498493605036+intron-Distal4.497533.47043HepG2KHSRP
chr109358975693589865+intron-Distal3.540373.95921HepG2U2AF2
chr109357947893579537+intron-Distal4.767513.73609HepG2KHSRP
chr109358655993586665+intron-Distal3.179073.04623HepG2KHSRP
chr109360527493605378+intron-Distal3.047253.96958K562KHSRP
chr109357942293579582+intron-Distal5.3367612.38486K562KHSRP
chr109358361993583754+intron-Distal4.524845.85485K562KHSRP
chr109360482693604898+intron-Distal,intron-Proximal3.627465.34065HepG2KHSRP
chr109360384293603906+intron-Distal3.239223.04623HepG2KHSRP
chr109360491893605019+intron-Distal4.068378.75493K562KHSRP
chr109358370793583784+intron-Distal3.247893.42396HepG2U2AF2
chr109358364193583736+intron-Distal3.154683.31157HepG2KHSRP
chr109360503693605099+intron-Distal3.499143.95921HepG2U2AF2
chr109360385093603926+intron-Distal3.278924.16517K562KHSRP
chr109356595293566008+intron-Distal3.927723.48210HepG2HNRNPL
chr109359195893592077+intron-Distal4.309993.88679HepG2CSTF2
chr109358665493586737+intron-Distal,intron-Proximal3.939003.49011K562KHSRP
chr109357699193577027+intron-Proximal4.734826.99120K562AQR
chr109355864693558656+intron-Proximal5.243367.23718K562AQR
chr109357698693576991+intron-Proximal4.464545.97994K562AQR
chr109360482393604884+intron-Proximal4.544636.28383K562KHSRP
chr109355865693558689+intron-Proximal5.243367.23718K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TNKS2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TNKS2 is not available on ENCORE database.

  • 72 RBPs can affect the levels of TNKS2.  








The Knockdown/knockout RNA-Seq assay for TNKS2 is not available on ENCORE database.





72 RBPs can affect the gene expression of TNKS2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TNKS2ENSG00000107854.51371.871401856.54210-0.436503.104902.10450HepG2ABCF1
TNKS2ENSG00000107854.52482.226901790.590600.471106.939005.78350HepG2AKAP8L
TNKS2ENSG00000107854.52118.962802657.11530-0.326505.231304.33700HepG2AUH
TNKS2ENSG00000107854.5837.152601632.04670-0.9631011.666209.68040HepG2BCCIP
TNKS2ENSG00000107854.51930.304701479.199100.383903.634702.95950HepG2BOP1
TNKS2ENSG00000107854.52475.848601634.699500.598809.482408.17810HepG2CALR
TNKS2ENSG00000107854.51797.272702224.51060-0.307702.181401.48990HepG2CIRBP
TNKS2ENSG00000107854.51093.901101358.02200-0.312001.943201.35590HepG2CPSF6
TNKS2ENSG00000107854.51879.055702164.32450-0.203902.046801.47900HepG2CELF1
TNKS2ENSG00000107854.51716.244201416.173400.277202.281701.46170HepG2DDX24
TNKS2ENSG00000107854.51350.270801704.97860-0.336504.448403.62670HepG2DKC1
TNKS2ENSG00000107854.51231.004501672.97230-0.442608.967407.87410HepG2DNAJC2
TNKS2ENSG00000107854.51959.119902473.96270-0.336602.094901.53650HepG2EIF4A3
TNKS2ENSG00000107854.53803.219203050.733800.318005.383304.59270HepG2ETF1
TNKS2ENSG00000107854.51413.590201741.56250-0.301002.590601.78340HepG2EWSR1
TNKS2ENSG00000107854.51866.071802495.85960-0.419503.665302.87760HepG2FXR1
TNKS2ENSG00000107854.51583.943702315.41520-0.547705.143104.24790HepG2G3BP1
TNKS2ENSG00000107854.51354.694501996.24850-0.559303.759702.45910HepG2GRSF1
TNKS2ENSG00000107854.51098.578301704.14780-0.633408.681807.63180HepG2HNRNPA1
TNKS2ENSG00000107854.51440.787801895.51620-0.395703.806403.00360HepG2HNRNPC
TNKS2ENSG00000107854.51380.385701610.42740-0.222402.106201.47420HepG2HNRNPF
TNKS2ENSG00000107854.51789.827402344.24220-0.389303.548102.76300HepG2HNRNPK
TNKS2ENSG00000107854.51267.311001585.81620-0.323503.101302.33760HepG2IGF2BP1
TNKS2ENSG00000107854.51654.019901923.41410-0.217702.919702.16910HepG2ILF2
TNKS2ENSG00000107854.51205.986401599.16950-0.407103.338002.00280HepG2LIN28B
TNKS2ENSG00000107854.51970.407102307.75990-0.228002.217901.53440HepG2NOL12
TNKS2ENSG00000107854.52813.123202288.845900.297502.034101.40670HepG2PABPC4
TNKS2ENSG00000107854.51593.414101863.87580-0.226202.407601.61330HepG2PARN
TNKS2ENSG00000107854.51432.162402148.89000-0.5854013.5155012.33490HepG2PCBP1
TNKS2ENSG00000107854.51387.267901951.98750-0.492703.756701.68000HepG2PPIG
TNKS2ENSG00000107854.51328.598101679.47940-0.338104.022303.15030HepG2PPIL4
TNKS2ENSG00000107854.52603.233702186.600400.251503.161702.58470HepG2PTBP1
TNKS2ENSG00000107854.52190.710601815.146700.271203.920603.21220HepG2PUS1
TNKS2ENSG00000107854.53054.662702368.090100.367205.129304.31850HepG2QKI
TNKS2ENSG00000107854.52363.555001748.447000.434802.039101.42510HepG2RAVER1
TNKS2ENSG00000107854.53239.743102149.213700.592009.908008.68890HepG2RBM25
TNKS2ENSG00000107854.51056.097701491.02630-0.497603.248902.09790HepG2RCC2
TNKS2ENSG00000107854.51938.249502266.47030-0.225702.594101.99460HepG2RECQL
TNKS2ENSG00000107854.51469.843702165.16880-0.558804.164803.18330HepG2RPS3A
TNKS2ENSG00000107854.51683.530901224.589400.459103.616202.73320HepG2RRP9
TNKS2ENSG00000107854.51154.960101676.90240-0.5380011.6346010.45440HepG2SAFB2
TNKS2ENSG00000107854.52838.174201905.150000.575004.134703.30170HepG2SF3A3
TNKS2ENSG00000107854.52682.794702276.489400.236803.017402.40310HepG2SF3B4
TNKS2ENSG00000107854.51215.807301955.58450-0.6857022.1245020.57750HepG2SMN1
TNKS2ENSG00000107854.54071.162902879.954500.4993014.7174013.80450HepG2SRFBP1
TNKS2ENSG00000107854.53247.068202376.180000.4504010.667209.87110HepG2SRSF1
TNKS2ENSG00000107854.52306.095101933.164400.254403.553702.94580HepG2SRSF9
TNKS2ENSG00000107854.52002.833002473.62930-0.304605.558704.73330HepG2SUCLG1
TNKS2ENSG00000107854.52736.618602135.852800.357505.194804.46670HepG2TAF15
TNKS2ENSG00000107854.51945.511901431.736600.442304.420303.53070HepG2TARDBP
TNKS2ENSG00000107854.51288.455101829.79760-0.506007.345606.60160HepG2TIAL1
TNKS2ENSG00000107854.5970.683701755.42020-0.854707.823405.46520HepG2TRA2A
TNKS2ENSG00000107854.51214.323401846.02120-0.6043014.0676012.93610HepG2TRIM56
TNKS2ENSG00000107854.51913.060401689.575700.179101.904301.30650HepG2UPF1
TNKS2ENSG00000107854.5817.522701462.81490-0.839406.864005.24130HepG2UPF2
TNKS2ENSG00000107854.51235.022401631.22060-0.401406.109205.27740HepG2UTP3
TNKS2ENSG00000107854.52371.934901719.121700.464302.760801.49610HepG2XRCC5
TNKS2ENSG00000107854.5877.853401572.47090-0.8410010.647509.24340HepG2XRN2
TNKS2ENSG00000107854.52373.699701746.626000.442502.832201.52080HepG2ZRANB2
TNKS2ENSG00000107854.51101.638901437.67040-0.384104.921404.20020K562AGGF1
TNKS2ENSG00000107854.51055.94020835.011200.338602.169501.40340K562BOP1
TNKS2ENSG00000107854.51247.869701563.83070-0.325603.629202.35450K562CPEB4
TNKS2ENSG00000107854.53153.028002620.875600.266602.880301.88650K562CELF1
TNKS2ENSG00000107854.5894.843101115.37980-0.317802.223001.46190K562FIP1L1
TNKS2ENSG00000107854.51292.235201041.100000.311703.073501.86840K562GLRX3
TNKS2ENSG00000107854.5826.940001587.47170-0.9409015.9993014.13760K562GRSF1
TNKS2ENSG00000107854.5441.85580851.70730-0.9468012.7047010.24800K562HNRNPF
TNKS2ENSG00000107854.5675.10540917.42620-0.442502.888301.93440K562HNRNPM
TNKS2ENSG00000107854.51576.842201300.349300.278002.630401.75940K562HNRNPU
TNKS2ENSG00000107854.5663.68010967.36930-0.543604.636202.64030K562LIN28B
TNKS2ENSG00000107854.5769.979701094.59020-0.507507.339206.07800K562MTPAP
TNKS2ENSG00000107854.5673.84930939.08430-0.478803.424801.77700K562NUSAP1
TNKS2ENSG00000107854.5628.12560931.15060-0.568005.542603.44860K562PHF6
TNKS2ENSG00000107854.5846.346701266.19170-0.581206.168604.86150K562PPIG
TNKS2ENSG00000107854.5523.82150855.11390-0.707007.023605.46630K562PSIP1
TNKS2ENSG00000107854.51021.093301359.67050-0.413104.320703.50810K562PTBP1
TNKS2ENSG00000107854.51008.069101303.86780-0.371203.040302.15450K562RBM22
TNKS2ENSG00000107854.5443.46310780.23660-0.8151010.372308.44930K562RCC2
TNKS2ENSG00000107854.5883.080501213.02520-0.458004.390302.13950K562RECQL
TNKS2ENSG00000107854.5557.44460739.63760-0.408002.791601.76170K562SRFBP1
TNKS2ENSG00000107854.51005.270901258.77770-0.324402.401901.43380K562SRSF5
TNKS2ENSG00000107854.5920.228201349.03740-0.551905.573004.54980K562TARDBP
TNKS2ENSG00000107854.5997.395801301.28660-0.383703.753702.78010K562TIA1
TNKS2ENSG00000107854.5862.133801276.83780-0.566606.300904.49060K562TRA2A
TNKS2ENSG00000107854.51002.552201289.49900-0.363104.632003.72820K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TNKS2 is not available on ENCORE database.





5 RBPs can affect the splicing of TNKS2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETNKS2ENSG00000107854.5chr10+936109729361109393605508936056979361478593614883-0.168000.003230.03250excludedK562AQR
SETNKS2ENSG00000107854.5chr10+935820529358211993579695935797909358677393586960-0.198000.000020.00043excludedK562AQR
SETNKS2ENSG00000107854.5chr10+9359438693594494935936099359378193596675935967550.088000.000010.00115includedHepG2HNRNPL
SETNKS2ENSG00000107854.5chr10+9359438693594560935936099359378193596675935967550.115000.000570.02509includedHepG2HNRNPC
A3SSTNKS2ENSG00000107854.5chr10+9359655293596755935966759359675593593609935937810.159000.001720.06240longerHepG2U2AF1
A5SSTNKS2ENSG00000107854.5chr10+935965529359675593596552935966419360031793600463-0.303000.000020.00352shorterK562U2AF1
A5SSTNKS2ENSG00000107854.5chr10+935965529359675593596552935966419360031793600463-0.272000.000690.02951shorterHepG2U2AF2
A5SSTNKS2ENSG00000107854.5chr10+935965529359675593596552935966419360031793600463-0.316000.000870.06634shorterHepG2U2AF1
MXETNKS2ENSG00000107854.5chr10+93596552935966419359667593596755935936099359378193600317936004630.223000.000000.000001includedHepG2U2AF1
MXETNKS2ENSG00000107854.5chr10+93596552935966419359667593596755935936099359378193600317936004630.140000.000000.000001includedK562U2AF1
MXETNKS2ENSG00000107854.5chr10+93596552935966419359667593596755935936099359378193600317936004630.159000.000000.000041includedHepG2U2AF2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TNKS2 is not avaliable on ENCORE database.