TMEM59

General Information

Gene Name : TMEM59
Gene ID : ENSG00000116209.11
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: TMEM59)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	TMEM59	ENSG00000116209.11	52.79	47.60	50.20	ENCSR000AEF
HepG2	TMEM59	ENSG00000116209.11	87.13	100.29	93.71	ENCSR985KAT
K562	TMEM59	ENSG00000116209.11	98.16	89.19	93.67	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for TMEM59 is not avaliable on ENCORE database.

Proteins bound to RNA

TMEM59 RNA is bound by 20 proteins.

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eCLIP assay for TMEM59 is not avaliable on ENCORE database.

20 proteins are bound to TMEM59 RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr1	54518739	54518863	-	5'-UTR,CDS,intron-Distal	4.84346	49.41302	HepG2	DDX3X
chr1	54497530	54497578	-	3'-UTR,intron-Distal,intron-Proximal	5.10517	30.75511	K562	TIA1
chr1	54502282	54502347	-	CDS,intron-Distal,intron-Proximal	4.89420	28.18544	K562	SND1
chr1	54518683	54518881	-	5'-UTR,CDS,intron-Distal,intron-Proximal	4.02133	22.85836	K562	RPS3
chr1	54497492	54497567	-	3'-UTR,intron-Distal,intron-Proximal	6.54026	22.20478	HepG2	TIA1
chr1	54518738	54518871	-	5'-UTR,CDS,intron-Distal,intron-Proximal	4.86964	21.95390	K562	DDX3X
chr1	54497483	54497530	-	3'-UTR,intron-Distal	4.79869	21.50903	K562	TIA1
chr1	54509100	54509180	-	CDS,intron-Distal	4.43002	20.07174	K562	SND1
chr1	54511364	54511460	-	5'-UTR,CDS,intron-Distal,intron-Proximal	3.54178	17.21850	K562	SND1
chr1	54518724	54518861	-	CDS,intron-Distal	4.80455	16.49042	HepG2	RPS3
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 56 entries

eCLIP assay for TMEM59 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for TMEM59 is not available on ENCORE database.
94 RBPs can affect the levels of TMEM59.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for TMEM59 is not available on ENCORE database.

94 RBPs can affect the gene expression of TMEM59 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
TMEM59	ENSG00000116209.7	2156.84700	4136.04440	-0.93930	40.29950	38.77760	HepG2	NELFE
TMEM59	ENSG00000116209.7	2060.70800	3852.14080	-0.90250	38.01660	36.24200	HepG2	RECQL
TMEM59	ENSG00000116209.7	5713.19560	2370.99790	1.26870	35.35960	33.36910	K562	PUS1
TMEM59	ENSG00000116209.7	2084.15680	3652.39350	-0.80940	30.59100	28.94400	HepG2	PCBP1
TMEM59	ENSG00000116209.7	4269.76750	2310.38250	0.88590	29.28800	27.27740	K562	RBM15
TMEM59	ENSG00000116209.7	2553.66810	1551.46290	0.71880	21.06850	19.90550	HepG2	ZNF622
TMEM59	ENSG00000116209.7	2722.43970	4038.71330	-0.56900	18.12000	17.13270	HepG2	SRSF1
TMEM59	ENSG00000116209.7	3358.11520	2169.07290	0.63050	18.09970	16.37310	HepG2	AKAP8L
TMEM59	ENSG00000116209.7	3462.57130	2297.82600	0.59150	17.53470	16.22880	K562	AGGF1
TMEM59	ENSG00000116209.7	4494.30950	2899.44930	0.63220	17.28140	16.21300	HepG2	RBM22
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 115 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for TMEM59 is not available on ENCORE database.

24 RBPs can affect the splicing of TMEM59 :

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Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	TMEM59	ENSG00000116209.7	chr1	-	54514322	54514355	54512939	54513045	54519028	54519085	0.85800	0.00000	0.00000	included	HepG2	U2AF1
SE	TMEM59	ENSG00000116209.7	chr1	-	54511364	54511459	54509057	54509198	54518672	54519078	-0.13400	0.00000	0.00000	excluded	K562	AQR
SE	TMEM59	ENSG00000116209.7	chr1	-	54512939	54513045	54509045	54509198	54518672	54518865	0.06400	0.00000	0.00060	included	HepG2	DDX3X
SE	TMEM59	ENSG00000116209.7	chr1	-	54511364	54511459	54509045	54509198	54518672	54519078	-0.07600	0.00000	0.00000	excluded	K562	PUS1
SE	TMEM59	ENSG00000116209.7	chr1	-	54512939	54513045	54509045	54509198	54518672	54518865	-0.14200	0.00000	0.00013	excluded	K562	RBM15
SE	TMEM59	ENSG00000116209.7	chr1	-	54512939	54513045	54511364	54511459	54519028	54519177	0.08000	0.00004	0.03262	included	HepG2	UPF1
SE	TMEM59	ENSG00000116209.7	chr1	-	54511364	54511459	54509045	54509198	54518672	54519078	-0.05200	0.00004	0.00266	excluded	K562	UTP18
SE	TMEM59	ENSG00000116209.7	chr1	-	54512939	54513045	54509045	54509198	54518672	54518865	0.06300	0.00005	0.00611	included	HepG2	NCBP2
SE	TMEM59	ENSG00000116209.7	chr1	-	54512939	54513045	54509045	54509198	54518672	54518865	0.06800	0.00007	0.00544	included	HepG2	MATR3
SE	TMEM59	ENSG00000116209.7	chr1	-	54512939	54513045	54509045	54509198	54518672	54518865	0.23800	0.00015	0.03629	included	K562	FTO

Showing 1 to 10 of 30 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

TMEM59

General Information

Functions

Localization

Domains (AlphaFold: TMEM59)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for TMEM59 is not avaliable on ENCORE database.

20 proteins are bound to TMEM59 RNA:

eCLIP assay for TMEM59 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for TMEM59 is not available on ENCORE database.

94 RBPs can affect the gene expression of TMEM59 :

The Knockdown/knockout RNA-Seq assay for TMEM59 is not available on ENCORE database.

24 RBPs can affect the splicing of TMEM59 :

The Knockdown/knockout RNA-Seq assay for TMEM59 is not avaliable on ENCORE database.