SPIRE1

General Information

Gene Name : SPIRE1
Gene ID : ENSG00000134278.15
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: SPIRE1)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	SPIRE1	ENSG00000134278.15	4.61	5.17	4.89	ENCSR000AEF
HepG2	SPIRE1	ENSG00000134278.15	9.45	8.43	8.94	ENCSR985KAT
K562	SPIRE1	ENSG00000134278.15	8.88	9.12	9.00	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for SPIRE1 is not avaliable on ENCORE database.

Proteins bound to RNA

SPIRE1 RNA is bound by 15 proteins.

CanvasJS.com

eCLIP assay for SPIRE1 is not avaliable on ENCORE database.

15 proteins are bound to SPIRE1 RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr18	12478190	12478302	-	intron-Distal	6.05738	48.30814	K562	AGGF1
chr18	12478228	12478314	-	intron-Distal	6.21257	22.39437	K562	HNRNPL
chr18	12478833	12478891	-	intron-Distal	4.83340	17.58670	K562	AGGF1
chr18	12478768	12478812	-	intron-Distal	5.79480	13.38324	K562	AGGF1
chr18	12478832	12478896	-	intron-Distal	5.46729	12.49233	K562	HNRNPL
chr18	12481497	12481583	-	intron-Distal	5.02005	11.62651	HepG2	U2AF2
chr18	12478180	12478228	-	intron-Distal	5.21590	11.16731	K562	HNRNPL
chr18	12478460	12478499	-	intron-Distal	4.25080	10.16849	K562	AGGF1
chr18	12478228	12478306	-	intron-Distal	4.56740	8.18013	HepG2	HNRNPL
chr18	12481686	12481744	-	intron-Distal	5.38853	8.16423	HepG2	U2AF2
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 33 entries

eCLIP assay for SPIRE1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for SPIRE1 is not available on ENCORE database.
96 RBPs can affect the levels of SPIRE1.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for SPIRE1 is not available on ENCORE database.

96 RBPs can affect the gene expression of SPIRE1 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
SPIRE1	ENSG00000134278.10	2247.45130	760.41010	1.56330	83.57600	81.81210	HepG2	SRFBP1
SPIRE1	ENSG00000134278.10	1151.16110	410.16470	1.48870	42.51660	40.86040	HepG2	SRSF9
SPIRE1	ENSG00000134278.10	1736.85620	490.50530	1.82400	37.90460	36.00940	HepG2	DDX6
SPIRE1	ENSG00000134278.10	158.18870	523.23980	-1.72580	25.81390	24.07360	K562	HNRNPC
SPIRE1	ENSG00000134278.10	1529.52870	805.48300	0.92510	25.03730	23.53930	HepG2	ETF1
SPIRE1	ENSG00000134278.10	1180.79230	571.13200	1.04780	14.12820	12.82330	HepG2	DDX3X
SPIRE1	ENSG00000134278.10	865.89180	522.62420	0.72830	13.77940	12.79240	HepG2	ZNF622
SPIRE1	ENSG00000134278.10	1277.29580	596.17000	1.09920	13.66340	12.57340	HepG2	AKAP1
SPIRE1	ENSG00000134278.10	220.58480	514.24780	-1.22110	13.67610	12.24610	HepG2	HNRNPC
SPIRE1	ENSG00000134278.10	484.93920	911.27400	-0.91010	11.70640	10.63770	K562	PUS1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 110 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for SPIRE1 is not available on ENCORE database.

7 RBPs can affect the splicing of SPIRE1 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	SPIRE1	ENSG00000134278.10	chr18	-	12485957	12485999			12479697	12479870	12493070	12493200	0.39800	0.00016	0.01040	included	HepG2	SF3B4
SE	SPIRE1	ENSG00000134278.10	chr18	-	12459753	12459927			12454344	12454482	12463349	12463492	-0.29900	0.00045	0.00716	excluded	HepG2	U2AF2
SE	SPIRE1	ENSG00000134278.10	chr18	-	12459753	12459927			12454344	12454482	12463349	12463492	-0.39100	0.00055	0.04239	excluded	HepG2	HNRNPL
SE	SPIRE1	ENSG00000134278.10	chr18	-	12459753	12459927			12454344	12454482	12463349	12463492	-0.26400	0.00062	0.04160	excluded	HepG2	RBM22
MXE	SPIRE1	ENSG00000134278.10	chr18	-	12506475	12506640	12512452	12512530	12496014	12496101	12535474	12535600	-0.17600	0.00340	0.04228	2included	K562	DROSHA
MXE	SPIRE1	ENSG00000134278.10	chr18	-	12496014	12496101	12512452	12512530	12493070	12493200	12535474	12535600	-0.15700	0.00447	0.02785	2included	HepG2	U2AF2
SE	SPIRE1	ENSG00000134278.10	chr18	-	12452253	12452390			12449666	12449895	12452483	12452511	-0.27200	0.00594	0.08659	excluded	HepG2	U2AF1
A3SS	SPIRE1	ENSG00000134278.10	chr18	-	12459753	12459987			12459753	12459927	12463349	12463492	0.15900	0.01963	0.09387	longer	K562	AQR

Showing 1 to 8 of 8 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

SPIRE1

General Information

Functions

Localization

Domains (AlphaFold: SPIRE1)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for SPIRE1 is not avaliable on ENCORE database.

15 proteins are bound to SPIRE1 RNA:

eCLIP assay for SPIRE1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for SPIRE1 is not available on ENCORE database.

96 RBPs can affect the gene expression of SPIRE1 :

The Knockdown/knockout RNA-Seq assay for SPIRE1 is not available on ENCORE database.

7 RBPs can affect the splicing of SPIRE1 :

The Knockdown/knockout RNA-Seq assay for SPIRE1 is not avaliable on ENCORE database.