RBBP8

General Information

Gene Name       : RBBP8
Gene ID             : ENSG00000101773.18
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: RBBP8)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878RBBP8ENSG00000101773.1860.2249.5854.90ENCSR000AEF
HepG2RBBP8ENSG00000101773.1819.0034.1226.56ENCSR985KAT
K562RBBP8ENSG00000101773.1830.4734.4232.45ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for RBBP8 is not avaliable on ENCORE database.



Proteins bound to RNA
  • RBBP8 RNA is bound by 7 proteins.  







eCLIP assay for RBBP8 is not avaliable on ENCORE database.





7 proteins are bound to RBBP8 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr182057089920570998+3'-UTR,CDS,intron-Proximal4.005596.14226K562ZNF622
chr182056486420564940+3'-UTR,CDS3.527134.20387K562ZNF622
chr182054876820548828+3'-UTR,CDS,intron-Proximal4.120823.36385K562UCHL5
chr182057368320573741+CDS,intron-Proximal4.305353.45943HepG2BCLAF1
chr182057761420577686+CDS3.241323.12941K562UCHL5
chr182057281020572908+CDS4.297434.48692K562YBX3
chr182057354620573604+CDS,intron-Proximal3.761624.09885HepG2BCLAF1
chr182057334320573428+CDS3.974813.22721K562YBX3
chr182058160120581665+CDS4.659553.89826HepG2BCLAF1
chr182056169620561749+intron-Distal3.502324.09242HepG2QKI
chr182052168020521791+intron-Distal3.959323.26999K562KHSRP
chr182055646320556573+intron-Distal3.946883.06150K562KHSRP
chr182058094120581074+intron-Distal3.767973.89889HepG2HNRNPL
chr182056707720567187+intron-Distal4.592615.20135HepG2QKI
chr182059899020599121+intron-Distal4.470055.20135HepG2QKI
chr182055660720556734+intron-Distal3.670305.61949K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for RBBP8 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for RBBP8 is not available on ENCORE database.

  • 111 RBPs can affect the levels of RBBP8.  








The Knockdown/knockout RNA-Seq assay for RBBP8 is not available on ENCORE database.





111 RBPs can affect the gene expression of RBBP8 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
RBBP8ENSG00000101773.12754.51230542.737500.475205.590504.78650HepG2ACO1
RBBP8ENSG00000101773.12930.46230529.333700.813707.265206.44800HepG2AKAP1
RBBP8ENSG00000101773.12232.67760387.82060-0.737104.451103.14130HepG2AKAP8
RBBP8ENSG00000101773.12293.51820438.00400-0.577502.945702.13650HepG2ASCC1
RBBP8ENSG00000101773.12910.07320629.915700.530703.607902.01320HepG2ATP5C1
RBBP8ENSG00000101773.12522.00130998.95050-0.9364020.2296018.68310HepG2AUH
RBBP8ENSG00000101773.12376.22110566.67620-0.590903.733702.70260HepG2BCLAF1
RBBP8ENSG00000101773.12741.733201071.17270-0.530204.996404.22390HepG2BOP1
RBBP8ENSG00000101773.12480.556701006.03110-1.065904.908603.59560HepG2CCAR1
RBBP8ENSG00000101773.12284.96350542.60650-0.9291014.0705012.81230HepG2CKAP4
RBBP8ENSG00000101773.12551.17190983.41040-0.835309.791908.57550HepG2CPSF6
RBBP8ENSG00000101773.12691.22120818.75010-0.244302.222101.54670HepG2DAZAP1
RBBP8ENSG00000101773.12638.23640456.088400.484702.026401.43520HepG2DDX21
RBBP8ENSG00000101773.12333.52560507.11500-0.604503.071902.41800HepG2DDX3X
RBBP8ENSG00000101773.12482.17300663.53290-0.460602.831301.80850HepG2DDX5
RBBP8ENSG00000101773.12295.41940435.49660-0.559902.845702.21980HepG2DDX6
RBBP8ENSG00000101773.12322.72030479.46570-0.571104.153302.96530HepG2DHX30
RBBP8ENSG00000101773.12251.21010497.13110-0.9847012.4858011.07970HepG2DNAJC21
RBBP8ENSG00000101773.12375.93230492.66900-0.390102.819802.16250HepG2DNAJC2
RBBP8ENSG00000101773.12264.45490418.77820-0.663203.545502.87840HepG2EIF2S1
RBBP8ENSG00000101773.12701.31050529.441100.405503.122601.87620HepG2EIF2S2
RBBP8ENSG00000101773.12797.94730450.543500.824506.138805.14410HepG2EIF4B
RBBP8ENSG00000101773.12540.62710773.72950-0.517202.695001.89070HepG2EIF4G2
RBBP8ENSG00000101773.12698.00620530.339900.396202.925002.06860HepG2EWSR1
RBBP8ENSG00000101773.12530.43890985.06380-0.893004.023202.79640HepG2FTO
RBBP8ENSG00000101773.12485.849701114.81460-1.1982016.5768015.13270HepG2GPKOW
RBBP8ENSG00000101773.12366.58270501.89290-0.453202.799402.14880HepG2HNRNPA1
RBBP8ENSG00000101773.12379.82930558.23910-0.555503.929903.11410HepG2HNRNPC
RBBP8ENSG00000101773.12466.63310884.72200-0.9229017.8814016.26220HepG2HNRNPF
RBBP8ENSG00000101773.12527.22620745.83710-0.500406.348205.36730HepG2HNRNPL
RBBP8ENSG00000101773.12541.299001063.88430-0.9748012.6694011.45140HepG2HNRNPLL
RBBP8ENSG00000101773.12481.23420871.19900-0.8563012.5285011.10400HepG2IGF2BP1
RBBP8ENSG00000101773.12685.33980413.078700.730302.225401.35170HepG2IGF2BP3
RBBP8ENSG00000101773.12666.89840466.985400.514003.417502.68830HepG2MAGOH
RBBP8ENSG00000101773.12688.94470469.628800.552803.551302.84440HepG2MATR3
RBBP8ENSG00000101773.12646.738101084.93110-0.746305.091703.75140HepG2MTPAP
RBBP8ENSG00000101773.12516.86490943.30610-0.8679010.350208.97820HepG2NSUN2
RBBP8ENSG00000101773.12613.84110432.016200.506704.221903.49970HepG2PCBP1
RBBP8ENSG00000101773.12379.99120572.57660-0.591503.184102.07190HepG2PCBP2
RBBP8ENSG00000101773.12502.18130640.28610-0.350502.786202.01070HepG2PRPF4
RBBP8ENSG00000101773.12262.68600494.65150-0.913107.389306.14540HepG2PRPF8
RBBP8ENSG00000101773.12548.28670439.577200.318702.137601.64480HepG2PTBP1
RBBP8ENSG00000101773.12303.63570774.98190-1.3518023.1209021.62090HepG2PUF60
RBBP8ENSG00000101773.121069.77550822.657800.378805.017004.26630HepG2PUM1
RBBP8ENSG00000101773.12601.70680822.06920-0.450204.188903.37280HepG2PUM2
RBBP8ENSG00000101773.12613.78030476.105800.366302.404501.81580HepG2QKI
RBBP8ENSG00000101773.12651.01300489.220000.412103.283302.70420HepG2NELFE
RBBP8ENSG00000101773.12560.71930455.618800.299401.846001.32820HepG2RECQL
RBBP8ENSG00000101773.12478.02700953.05660-0.9955014.5209013.18940HepG2RPLP0
RBBP8ENSG00000101773.12344.79810489.31450-0.505002.539901.78320HepG2RRP9
RBBP8ENSG00000101773.12913.40830601.136000.603503.480001.76790HepG2RTF1
RBBP8ENSG00000101773.12509.01740727.73500-0.515702.846502.16190HepG2SF3A3
RBBP8ENSG00000101773.12839.822301053.05980-0.326402.185101.55350HepG2SF3B1
RBBP8ENSG00000101773.12582.98430457.684200.349002.414701.85680HepG2SF3B4
RBBP8ENSG00000101773.12503.93180743.04640-0.560207.452306.38640HepG2SLBP
RBBP8ENSG00000101773.12515.660101171.70490-1.1841011.515009.93810HepG2SNRNP70
RBBP8ENSG00000101773.121141.64200477.712001.2568033.8385032.58570HepG2SRSF1
RBBP8ENSG00000101773.12842.741201133.02640-0.427002.466901.52710HepG2SRSF3
RBBP8ENSG00000101773.12465.52000869.20880-0.9009017.0162015.55030HepG2SRSF7
RBBP8ENSG00000101773.12217.65170388.63440-0.836408.750007.86590HepG2SRSF9
RBBP8ENSG00000101773.12531.59390940.05700-0.8224015.8482014.82780HepG2SSB
RBBP8ENSG00000101773.12325.19570475.92140-0.549403.609802.54470HepG2SUPT6H
RBBP8ENSG00000101773.12361.26520638.30870-0.821206.445505.47850HepG2SUPV3L1
RBBP8ENSG00000101773.12613.67570429.354900.515204.560003.86810HepG2TAF15
RBBP8ENSG00000101773.12563.197101036.84540-0.8805011.4022010.08080HepG2TARDBP
RBBP8ENSG00000101773.12251.04230538.93900-1.1022014.8730013.87730HepG2TIAL1
RBBP8ENSG00000101773.12299.02020543.66020-0.862508.889407.96810HepG2TRIM56
RBBP8ENSG00000101773.12404.97740645.38920-0.672308.624207.50510HepG2UPF1
RBBP8ENSG00000101773.12401.30500663.37340-0.725109.361407.57160HepG2UTP18
RBBP8ENSG00000101773.12916.33300623.098600.556307.367506.46800HepG2UTP3
RBBP8ENSG00000101773.12839.25840543.346300.627103.877702.37770HepG2XRCC5
RBBP8ENSG00000101773.12855.50740607.659400.493402.707501.66440HepG2XRCC6
RBBP8ENSG00000101773.12418.65790628.34480-0.585803.909603.05630HepG2XRN2
RBBP8ENSG00000101773.12441.67950709.80520-0.6844010.676009.77650HepG2ZNF622
RBBP8ENSG00000101773.121386.41660894.788400.631607.291305.31660K562AARS
RBBP8ENSG00000101773.12846.232201265.68100-0.580807.268206.41220K562AGGF1
RBBP8ENSG00000101773.12786.244901390.64410-0.8227013.0193010.48450K562AKAP8
RBBP8ENSG00000101773.12915.794401316.96210-0.524102.442401.82810K562AKAP8L
RBBP8ENSG00000101773.12770.548001757.23300-1.1893024.3965022.84580K562AQR
RBBP8ENSG00000101773.121545.081402080.89460-0.429504.878702.20810K562AUH
RBBP8ENSG00000101773.12800.273701063.10030-0.409704.528502.78060K562BCCIP
RBBP8ENSG00000101773.12754.150501154.09610-0.613803.965202.91860K562BOP1
RBBP8ENSG00000101773.12856.547501586.79170-0.889503.616601.93020K562CKAP4
RBBP8ENSG00000101773.121264.221701736.48840-0.457906.837505.06630K562CPEB4
RBBP8ENSG00000101773.12889.133201227.20290-0.464902.770901.98820K562CPSF6
RBBP8ENSG00000101773.12830.832601119.91720-0.430805.186203.48920K562DDX21
RBBP8ENSG00000101773.12520.22510692.55730-0.412803.201902.07600K562DDX3X
RBBP8ENSG00000101773.12494.03610702.14680-0.507205.226303.23770K562DDX6
RBBP8ENSG00000101773.121744.909301417.373800.299803.023702.10160K562DKC1
RBBP8ENSG00000101773.12414.30440834.10650-1.0095012.7305010.60040K562EFTUD2
RBBP8ENSG00000101773.12602.34070760.65140-0.336703.037301.75840K562EIF2S1
RBBP8ENSG00000101773.121141.741201488.64190-0.382803.843203.01720K562EIF2S2
RBBP8ENSG00000101773.12600.19350893.18820-0.573504.068202.78190K562EIF3D
RBBP8ENSG00000101773.12571.14920723.52790-0.341202.262701.51830K562EIF4A3
RBBP8ENSG00000101773.12805.363401248.51900-0.632504.535403.43750K562FMR1
RBBP8ENSG00000101773.12718.339501058.17570-0.558803.022202.06240K562FTO
RBBP8ENSG00000101773.121121.69140752.434500.575908.290307.31280K562FXR1
RBBP8ENSG00000101773.121158.01510811.121300.513603.399402.60040K562G3BP2
RBBP8ENSG00000101773.12617.049901171.73080-0.925207.568206.25120K562GPKOW
RBBP8ENSG00000101773.121092.570801983.94350-0.8606010.174308.70100K562GRSF1
RBBP8ENSG00000101773.12552.78990979.58600-0.825405.618604.79730K562HNRNPC
RBBP8ENSG00000101773.12721.30450974.90700-0.434702.725401.70860K562IGF2BP2
RBBP8ENSG00000101773.12416.459401000.37030-1.2643010.020608.12410K562KRR1
RBBP8ENSG00000101773.12823.434901143.71720-0.474002.823501.93680K562METAP2
RBBP8ENSG00000101773.121705.877802381.65780-0.481502.547901.46780K562MSI2
RBBP8ENSG00000101773.12897.941001278.48430-0.509708.198706.87630K562MTPAP
RBBP8ENSG00000101773.121063.456701420.44220-0.417607.441806.30200K562NSUN2
RBBP8ENSG00000101773.12623.282401387.02700-1.154006.954105.15740K562PABPN1
RBBP8ENSG00000101773.12880.051801649.70180-0.906504.497702.47020K562PPP1R8
RBBP8ENSG00000101773.12568.66120878.23920-0.627003.321002.31740K562PSIP1
RBBP8ENSG00000101773.121273.90510995.545200.355603.277702.56110K562PTBP1
RBBP8ENSG00000101773.121804.537602437.88130-0.434002.287701.54590K562PUF60
RBBP8ENSG00000101773.12796.673601306.32550-0.713507.180706.35200K562PUS1
RBBP8ENSG00000101773.12935.224001272.60150-0.444404.957104.18450K562RBM15
RBBP8ENSG00000101773.12754.14660954.66560-0.340202.393301.61580K562RBM22
RBBP8ENSG00000101773.121039.465401706.50910-0.715202.908801.32550K562RBM39
RBBP8ENSG00000101773.12529.376001268.87060-1.261206.906904.72630K562SF1
RBBP8ENSG00000101773.12725.439001401.71610-0.9503022.8156020.68970K562SF3A3
RBBP8ENSG00000101773.12793.668901114.16070-0.489302.727101.75990K562SF3B1
RBBP8ENSG00000101773.12583.33090843.96670-0.532905.647204.39930K562SF3B4
RBBP8ENSG00000101773.12943.282901547.47700-0.714202.890501.54720K562SFPQ
RBBP8ENSG00000101773.12863.961301456.59970-0.753603.219101.85930K562SNRNP200
RBBP8ENSG00000101773.12542.76880759.33840-0.484402.683201.67900K562SRFBP1
RBBP8ENSG00000101773.121158.422701436.09760-0.310002.822501.87910K562SRPK2
RBBP8ENSG00000101773.121514.17960975.954600.633609.217607.93670K562SRSF1
RBBP8ENSG00000101773.12714.00360921.68680-0.368302.692501.66150K562SRSF5
RBBP8ENSG00000101773.12909.747301742.74600-0.937804.820702.75660K562SUPT6H
RBBP8ENSG00000101773.121237.07110763.776700.6956010.642809.03180K562SYNCRIP
RBBP8ENSG00000101773.12710.14550987.75480-0.476003.907503.05950K562TARDBP
RBBP8ENSG00000101773.12764.76270952.79450-0.317202.405801.64840K562TIA1
RBBP8ENSG00000101773.12525.83400844.75560-0.683903.554302.49010K562TIAL1
RBBP8ENSG00000101773.12493.84050897.10900-0.861205.757804.27920K562TRIM56
RBBP8ENSG00000101773.12560.38560831.83930-0.569904.550803.21250K562UCHL5
RBBP8ENSG00000101773.121039.407601506.13040-0.5351010.007308.75100K562UPF1
RBBP8ENSG00000101773.12743.706701324.21440-0.832303.497801.98690K562UTP18
RBBP8ENSG00000101773.12838.643301288.73930-0.619808.105306.56640K562WDR3
RBBP8ENSG00000101773.12972.948601340.20040-0.462007.737806.39040K562WDR43
RBBP8ENSG00000101773.121246.666501979.70660-0.667209.913608.16360K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for RBBP8 is not available on ENCORE database.





13 RBPs can affect the splicing of RBBP8 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SERBBP8ENSG00000101773.12chr18+2053729320537359205295802052967620548768205488810.102000.000110.00299includedHepG2U2AF1
SERBBP8ENSG00000101773.12chr18+2053729320537359205295802052967620548768205488810.066000.000990.01216includedK562AQR
SERBBP8ENSG00000101773.12chr18+205736832057381020572710205736022057633620576425-0.093000.000170.00275excludedK562AQR
SERBBP8ENSG00000101773.12chr18+205487682054888120529580205296762055511520555182-0.102000.001730.01935excludedK562AQR
SERBBP8ENSG00000101773.12chr18+206020912060223320596760205968872060610520606449-0.087000.000200.00316excludedK562AQR
SERBBP8ENSG00000101773.12chr18+205863252058639520581548205816922059679020596887-0.100000.002380.02536excludedK562AQR
SERBBP8ENSG00000101773.12chr18+2053729320537359205295802052967620548768205488810.067000.000000.00065includedK562DROSHA
SERBBP8ENSG00000101773.12chr18+205863252058639520581548205816922059679020596887-0.115000.000070.02222excludedK562MTPAP
SERBBP8ENSG00000101773.12chr18+205863252058639520581548205816922059679020596887-0.098000.000160.03323excludedK562NSUN2
SERBBP8ENSG00000101773.12chr18+2052150620521557205167162051692320526406205264490.073000.002640.09078includedHepG2SFPQ
SERBBP8ENSG00000101773.12chr18+2053729320537359205295802052967620548768205488810.052000.000020.00741includedK562LARP4
SERBBP8ENSG00000101773.12chr18+2058632520586395205815482058169220596790205968870.097000.000530.05741includedHepG2LARP4
SERBBP8ENSG00000101773.12chr18+205372932053735920529580205296762054876820548881-0.051000.000320.07686excludedK562PPIL4
SERBBP8ENSG00000101773.12chr18+205372932053735920529580205296762054876820548881-0.066000.000000.00278excludedK562SBDS
SERBBP8ENSG00000101773.12chr18+205551152055518220548768205488812056218020562356-0.052000.002630.06974excludedK562UTP18
SERBBP8ENSG00000101773.12chr18+205551152055518220548768205488812056218020562356-0.060000.002530.05483excludedK562RBM15
SERBBP8ENSG00000101773.12chr18+205551152055518220548768205488812056218020562356-0.055000.002080.04896excludedK562AGGF1
SERBBP8ENSG00000101773.12chr18+2053729320537359205295802052967620548768205488810.213000.000000.00000includedK562HNRNPC
SERBBP8ENSG00000101773.12chr18+205863252058639520581548205816922059679020596887-0.133000.001960.03335excludedK562HNRNPC
A3SSRBBP8ENSG00000101773.12chr18+2058153320581692205815482058169220577531205776970.126000.000010.00007longerK562AQR
MXERBBP8ENSG00000101773.12chr18+20596760205968872060209120602233205863252058639520606105206064490.109000.000010.000111includedK562AQR
MXERBBP8ENSG00000101773.12chr18+20596790205968872060209120602233205815482058169220606105206064490.139000.001500.012941includedK562AQR
MXERBBP8ENSG00000101773.12chr18+20596799205968872060209120602233205863252058639520606105206064490.078000.000800.007541includedK562AQR
MXERBBP8ENSG00000101773.12chr18+20537293205373592054876820548881205295802052967620555115205551820.086000.000890.018751includedK562HNRNPC

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for RBBP8 is not avaliable on ENCORE database.