MRPL4

General Information

Gene Name       : MRPL4
Gene ID             : ENSG00000105364.13
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: MRPL4)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MRPL4ENSG00000105364.136.0030.2218.11ENCSR000AEF
HepG2MRPL4ENSG00000105364.1389.9818.7554.37ENCSR985KAT
K562MRPL4ENSG00000105364.13110.4947.8979.19ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MRPL4 is not avaliable on ENCORE database.



Proteins bound to RNA
  • MRPL4 RNA is bound by 19 proteins.  







eCLIP assay for MRPL4 is not avaliable on ENCORE database.





19 proteins are bound to MRPL4 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr191036933910369396+3'-UTR,CDS,intron-Proximal3.9701512.79935HepG2PRPF8
chr191037059510370654+3'-UTR3.193573.34573K562IGF2BP2
chr191036935810369407+3'-UTR,CDS,intron-Proximal5.346026.75320K562AQR
chr191037058010370667+3'-UTR4.726406.13673K562RBM15
chr191037060610370694+3'-UTR4.337767.71026K562PABPC4
chr191036932210369370+3'-UTR,CDS,intron-Proximal4.037814.75425K562EFTUD2
chr191036909610369188+3'-UTR,CDS3.995383.39686HepG2G3BP1
chr191037036410370503+3'-UTR,CDS4.6102214.32541HepG2PCBP2
chr191036923110369288+3'-UTR,CDS,intron-Proximal4.274464.22551K562SF3B4
chr191036933810369393+3'-UTR,CDS,intron-Proximal4.923115.58150K562SF3B4
chr191037047510370596+3'-UTR,CDS3.8034022.58411K562PABPC4
chr191036916810369199+3'-UTR,CDS,intron-Proximal4.0880715.41209K562YBX3
chr191037040810370476+3'-UTR,CDS5.389479.36006HepG2LARP4
chr191036924810369323+3'-UTR,CDS,intron-Proximal4.544677.83317HepG2BUD13
chr191037047610370582+3'-UTR,CDS4.0281811.72056HepG2LARP4
chr191036893310368980+3'-UTR,CDS3.4639911.24658K562YBX3
chr191036915810369168+3'-UTR,CDS3.9963513.50128K562YBX3
chr191036913010369158+3'-UTR,CDS3.640008.70833K562YBX3
chr191037039610370480+3'-UTR,CDS3.5819810.10327K562PCBP1
chr191036890510368968+3'-UTR,CDS4.376694.76200K562BUD13
chr191036914810369194+3'-UTR,CDS4.345744.60160HepG2LARP4
chr191037037810370549+3'-UTR,CDS3.1078621.86059K562DDX55
chr191037048510370573+3'-UTR,CDS5.036356.89039K562RBM15
chr191036289210362986+5'-UTR,CDS5.6722015.31047HepG2DDX3X
chr191036293010362987+5'-UTR,CDS,intron-Proximal5.1379018.61638K562DDX3X
chr191036289210362930+5'-UTR6.003256.26070K562DDX3X
chr191036986310369939+CDS,intron-Distal4.523555.86125HepG2HNRNPK
chr191036326110363374+CDS4.151828.43072HepG2DDX3X
chr191036737910367502+CDS,intron-Distal,intron-Proximal3.015939.43226HepG2PPIG
chr191036322610363244+CDS,intron-Proximal4.397754.66990HepG2DDX3X
chr191036307110363095+CDS,intron-Proximal3.8115610.26816K562DDX3X
chr191036307810363140+CDS,intron-Proximal3.873297.77439HepG2DDX3X
chr191036526410365316+CDS,intron-Proximal3.207005.97131K562DDX3X
chr191036995310370034+CDS,intron-Distal4.316034.33022HepG2HNRNPK
chr191036526210365320+CDS,intron-Proximal4.647444.08604HepG2PPIG
chr191036889710368951+CDS,intron-Proximal4.402516.32078HepG2RPS3
chr191036772910367805+intron-Distal3.119573.48223HepG2RBFOX2
chr191036772510367803+intron-Distal4.293184.35475K562RBFOX2
chr191036753610367596+intron-Distal,intron-Proximal5.156365.58036HepG2EFTUD2
chr191036532310365417+intron-Distal,intron-Proximal3.635576.34662HepG2PRPF8
chr191036534610365408+intron-Proximal4.062176.89981K562EFTUD2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MRPL4 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MRPL4 is not available on ENCORE database.

  • 116 RBPs can affect the levels of MRPL4.  








The Knockdown/knockout RNA-Seq assay for MRPL4 is not available on ENCORE database.





116 RBPs can affect the gene expression of MRPL4 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MRPL4ENSG00000105364.91119.85810902.885000.310602.147301.61520HepG2BOP1
MRPL4ENSG00000105364.9440.45240577.86540-0.391702.163901.47620HepG2CALR
MRPL4ENSG00000105364.9848.11450700.439600.275902.418701.78860HepG2CKAP4
MRPL4ENSG00000105364.9558.14420828.90320-0.570604.741303.86160HepG2CPSF6
MRPL4ENSG00000105364.9386.03510239.356800.689504.340603.06890HepG2YBX3
MRPL4ENSG00000105364.9613.98260480.177700.354503.320702.52160HepG2DAZAP1
MRPL4ENSG00000105364.9347.80560239.690600.537003.320702.05270HepG2DDX1
MRPL4ENSG00000105364.9637.75420941.27860-0.561602.558401.61970HepG2DDX59
MRPL4ENSG00000105364.9343.82020235.030200.548703.711302.90360HepG2DNAJC21
MRPL4ENSG00000105364.9481.44130232.955201.0472016.2692014.81570HepG2DNAJC2
MRPL4ENSG00000105364.9664.98070452.075300.556603.687802.63450HepG2EEF2
MRPL4ENSG00000105364.9355.31310473.79500-0.415202.625901.80740HepG2EIF4G1
MRPL4ENSG00000105364.9920.806301091.30200-0.245102.298401.74160HepG2ETF1
MRPL4ENSG00000105364.9857.90320684.601900.325402.280301.52250HepG2EWSR1
MRPL4ENSG00000105364.9468.63850328.051600.514503.722802.34820HepG2FAM120A
MRPL4ENSG00000105364.9422.19860647.36710-0.616704.706003.69710HepG2FUBP3
MRPL4ENSG00000105364.9484.59230326.688000.568803.713902.66230HepG2GEMIN5
MRPL4ENSG00000105364.9383.23270224.239200.773103.221301.74930HepG2HNRNPA0
MRPL4ENSG00000105364.9397.06770218.937500.858805.626503.56860HepG2HNRNPAB
MRPL4ENSG00000105364.9736.81060569.658800.371103.231702.46190HepG2HNRNPF
MRPL4ENSG00000105364.9908.92020580.804800.646002.451701.79190HepG2HNRNPK
MRPL4ENSG00000105364.9609.05090437.380300.477605.411704.49530HepG2HNRNPL
MRPL4ENSG00000105364.9471.49900262.187300.8466010.322109.21370HepG2HNRNPU
MRPL4ENSG00000105364.9730.59920560.948700.381102.859302.12290HepG2IGF2BP1
MRPL4ENSG00000105364.9398.62110267.815700.573705.338204.34620HepG2ILF2
MRPL4ENSG00000105364.9440.30800252.641300.801303.694702.28590HepG2KHDRBS1
MRPL4ENSG00000105364.91158.63950621.431300.898703.583402.87330HepG2MATR3
MRPL4ENSG00000105364.9595.37560835.79840-0.489403.982603.01660HepG2MSI2
MRPL4ENSG00000105364.9604.01060914.50040-0.598403.215702.16570HepG2MTPAP
MRPL4ENSG00000105364.9989.99940635.986400.638302.315401.73370HepG2NCBP2
MRPL4ENSG00000105364.9633.32820327.445300.951605.275303.31860HepG2NOLC1
MRPL4ENSG00000105364.9601.01030354.916800.759802.866401.75110HepG2NONO
MRPL4ENSG00000105364.9547.91420795.09910-0.537204.237203.31600HepG2NSUN2
MRPL4ENSG00000105364.9341.03550259.520400.394002.218001.45190HepG2PARN
MRPL4ENSG00000105364.9907.29730600.929700.594308.508007.53970HepG2PCBP1
MRPL4ENSG00000105364.9492.68190233.850101.075004.857703.90960HepG2PPIL4
MRPL4ENSG00000105364.9491.85980604.37250-0.297202.149101.46010HepG2PRPF4
MRPL4ENSG00000105364.9746.73950454.547100.716108.055707.11030HepG2PUF60
MRPL4ENSG00000105364.9887.08930482.548300.8783020.0866018.78590HepG2PUM1
MRPL4ENSG00000105364.9496.20410662.24020-0.416403.252202.58280HepG2QKI
MRPL4ENSG00000105364.9498.10070312.824500.671004.301502.10350HepG2RBM14
MRPL4ENSG00000105364.9627.387301004.28710-0.678709.156907.71910HepG2RBM15
MRPL4ENSG00000105364.9745.64520912.11480-0.290702.322801.83710HepG2RBM22
MRPL4ENSG00000105364.9430.78950601.02190-0.480403.624802.86020HepG2RBM25
MRPL4ENSG00000105364.9654.82930306.648601.094403.099402.04730HepG2RBM27
MRPL4ENSG00000105364.9515.66610357.093600.530003.733003.02990HepG2RPS19
MRPL4ENSG00000105364.9482.21600266.209300.857003.890302.94210HepG2RPS3A
MRPL4ENSG00000105364.9557.34640288.693100.948902.330701.34980HepG2RPS5
MRPL4ENSG00000105364.9504.53930233.489301.1115017.0960015.69060HepG2SAFB2
MRPL4ENSG00000105364.9501.97580250.673401.001706.354304.39400HepG2SART3
MRPL4ENSG00000105364.91381.54390888.143300.637305.170304.23030HepG2SF3A3
MRPL4ENSG00000105364.9651.05820435.894200.578707.536706.46580HepG2SLBP
MRPL4ENSG00000105364.9472.90810272.287900.796309.715908.62670HepG2SMN1
MRPL4ENSG00000105364.9658.96930987.58570-0.583703.279602.42590HepG2SNRNP70
MRPL4ENSG00000105364.9772.196501030.17930-0.415905.396404.76060HepG2SRFBP1
MRPL4ENSG00000105364.9713.01230448.830800.667709.350508.29090HepG2SRSF5
MRPL4ENSG00000105364.9329.15220540.59600-0.715808.731007.84700HepG2SRSF9
MRPL4ENSG00000105364.9400.83610231.684100.790804.172602.79380HepG2STIP1
MRPL4ENSG00000105364.9849.51180510.417100.7349013.3426012.14650HepG2SUCLG1
MRPL4ENSG00000105364.9186.22460597.26120-1.6813032.0030030.37170HepG2TAF15
MRPL4ENSG00000105364.9491.93720254.763500.9492010.633609.76340HepG2TIAL1
MRPL4ENSG00000105364.9582.29640257.041401.1797020.7274019.36560HepG2TRIM56
MRPL4ENSG00000105364.9768.27030444.116500.790602.320101.52620HepG2TUFM
MRPL4ENSG00000105364.91101.70560760.443300.534708.376707.42570HepG2UTP3
MRPL4ENSG00000105364.9431.72190238.462400.856205.669104.10260HepG2XPO5
MRPL4ENSG00000105364.9390.45880596.45770-0.611205.999705.07100HepG2ZC3H8
MRPL4ENSG00000105364.91540.258202108.03560-0.452702.600901.42460K562ABCF1
MRPL4ENSG00000105364.92584.410401610.853600.6819018.8379017.47950K562AGGF1
MRPL4ENSG00000105364.91328.718401006.264700.400905.037502.94940K562AKAP1
MRPL4ENSG00000105364.92326.103601676.147000.472703.146302.44840K562AKAP8L
MRPL4ENSG00000105364.92203.143901758.645400.325003.847402.75530K562ATP5C1
MRPL4ENSG00000105364.9861.037201417.22280-0.718908.726907.12830K562BOP1
MRPL4ENSG00000105364.9962.310401506.91730-0.647009.865208.37000K562CPSF6
MRPL4ENSG00000105364.92334.144503139.35240-0.427604.755603.46510K562CELF1
MRPL4ENSG00000105364.92918.168202442.546400.256603.418502.70490K562DDX47
MRPL4ENSG00000105364.91329.956101033.671100.363502.884601.54100K562DDX6
MRPL4ENSG00000105364.92670.497001803.774800.5660011.744209.69110K562DKC1
MRPL4ENSG00000105364.91394.890701677.14000-0.265902.804302.08090K562EIF2S2
MRPL4ENSG00000105364.9605.49880341.334400.8268010.215108.67930K562EIF3G
MRPL4ENSG00000105364.91149.945601610.81400-0.486203.110901.38050K562ESF1
MRPL4ENSG00000105364.9911.090401533.24710-0.7509010.320408.61560K562FMR1
MRPL4ENSG00000105364.9768.105901299.56280-0.758608.929207.19810K562FTO
MRPL4ENSG00000105364.9209.49630301.77620-0.526602.940301.55110K562FUS
MRPL4ENSG00000105364.91516.867601107.705900.453406.122505.27490K562FXR1
MRPL4ENSG00000105364.939.34200169.82520-2.1099010.308508.77670K562G3BP2
MRPL4ENSG00000105364.91793.613102171.15920-0.275603.059801.85840K562GLRX3
MRPL4ENSG00000105364.91023.526401438.73750-0.491305.125004.04970K562GPKOW
MRPL4ENSG00000105364.9938.443801453.06820-0.630808.054007.08530K562HNRNPC
MRPL4ENSG00000105364.91064.39100462.544401.202303.052901.95560K562IGF2BP2
MRPL4ENSG00000105364.9706.00570470.385400.585705.466703.68880K562IGF2BP3
MRPL4ENSG00000105364.9698.543201228.49640-0.814507.391905.78350K562KRR1
MRPL4ENSG00000105364.9906.90480485.906000.9002013.3624011.39210K562MAGOH
MRPL4ENSG00000105364.92106.004501702.769600.306502.244501.30890K562MAK16
MRPL4ENSG00000105364.9848.64630484.888400.807405.810704.40220K562MATR3
MRPL4ENSG00000105364.92592.199301992.783600.379304.346003.15770K562MBNL1
MRPL4ENSG00000105364.91710.095002282.67640-0.416607.810606.51270K562MTPAP
MRPL4ENSG00000105364.91992.758002536.33920-0.348008.264207.07340K562NSUN2
MRPL4ENSG00000105364.91898.224801283.536500.564402.320601.42930K562PABPN1
MRPL4ENSG00000105364.9680.56550475.070800.518503.433301.92330K562PCBP1
MRPL4ENSG00000105364.9867.812901803.83830-1.055602.410901.63560K562PCBP3
MRPL4ENSG00000105364.92231.144601719.810200.375402.476601.70450K562PPIG
MRPL4ENSG00000105364.9913.68750472.103800.9525015.6674014.15300K562PTBP1
MRPL4ENSG00000105364.92205.843502962.95100-0.425704.305002.95230K562PUM1
MRPL4ENSG00000105364.92214.207302902.38540-0.390404.943103.64820K562PUM2
MRPL4ENSG00000105364.9302.90150189.855200.673804.449402.14900K562QKI
MRPL4ENSG00000105364.92161.458201619.659400.416201.822001.32280K562RBM15
MRPL4ENSG00000105364.9686.39620452.576500.600802.715201.88290K562RBM22
MRPL4ENSG00000105364.9722.82750441.263500.711903.742602.04260K562RBM34
MRPL4ENSG00000105364.9857.97520499.523600.780307.302205.57790K562RPS3
MRPL4ENSG00000105364.91894.974001233.236100.619602.469701.45050K562SAFB
MRPL4ENSG00000105364.91859.059802502.59940-0.428902.873202.04500K562SF3A3
MRPL4ENSG00000105364.9895.626701368.28210-0.611405.530904.12250K562SF3B1
MRPL4ENSG00000105364.9447.93200176.408201.3443018.6443016.24640K562SF3B4
MRPL4ENSG00000105364.9182.11240313.42630-0.783305.157302.81070K562SND1
MRPL4ENSG00000105364.91426.760901127.296800.339802.623201.63290K562SRFBP1
MRPL4ENSG00000105364.91972.969302563.95620-0.378008.109906.60650K562SRPK2
MRPL4ENSG00000105364.91080.37790462.842701.2228013.4481011.88920K562SRSF1
MRPL4ENSG00000105364.9882.19120482.148800.8715011.192908.94610K562SRSF4
MRPL4ENSG00000105364.9826.76420437.178400.919204.045302.73410K562SRSF5
MRPL4ENSG00000105364.9248.75370352.09700-0.501302.921601.60040K562SSB
MRPL4ENSG00000105364.91166.799601988.10440-0.768804.391102.64240K562SSRP1
MRPL4ENSG00000105364.9993.076001612.49190-0.699303.107101.56550K562SUPT6H
MRPL4ENSG00000105364.9909.82850468.376300.957808.746707.39660K562TARDBP
MRPL4ENSG00000105364.91065.64400451.815101.2378015.2414013.20290K562TIA1
MRPL4ENSG00000105364.9905.45900443.485201.029703.879502.55380K562TRA2A
MRPL4ENSG00000105364.91713.236702689.32790-0.6505019.4021017.68810K562UPF1
MRPL4ENSG00000105364.91280.792901769.76520-0.466502.712101.52380K562UTP3
MRPL4ENSG00000105364.91615.086702301.18330-0.510807.157105.70860K562WDR3
MRPL4ENSG00000105364.91842.607102392.89200-0.377005.046903.93410K562WDR43
MRPL4ENSG00000105364.91944.877902422.02760-0.316502.678901.41540K562WRN
MRPL4ENSG00000105364.91717.647402303.51140-0.423404.587403.43420K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MRPL4 is not available on ENCORE database.





2 RBPs can affect the splicing of MRPL4 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEMRPL4ENSG00000105364.9chr19+1036984710370083103692841036936110370292103704540.158000.000000.00000includedHepG2HNRNPK
SEMRPL4ENSG00000105364.9chr19+1036984710370083103692841036936110370292103704540.295000.000000.00000includedK562HNRNPK
RIMRPL4ENSG00000105364.9chr19+1036307210363377103630721036313910363226103633770.134000.000000.00000includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MRPL4 is not avaliable on ENCORE database.