LRP6

General Information

Gene Name : LRP6
Gene ID : ENSG00000070018.8
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: LRP6)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	LRP6	ENSG00000070018.8	3.84	4.18	4.01	ENCSR000AEF
HepG2	LRP6	ENSG00000070018.8	17.04	17.33	17.18	ENCSR985KAT
K562	LRP6	ENSG00000070018.8	7.62	5.24	6.43	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for LRP6 is not avaliable on ENCORE database.

Proteins bound to RNA

LRP6 RNA is bound by 26 proteins.

eCLIP assay for LRP6 is not avaliable on ENCORE database.

26 proteins are bound to LRP6 RNA:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr12	12269147	12269248	-	3'-UTR,intron-Distal	4.07221	3.44480	HepG2	TIA1
chr12	12274028	12274071	-	3'-UTR,CDS,intron-Distal	4.33851	7.87748	K562	PUM2
chr12	12274279	12274355	-	3'-UTR,CDS,intron-Distal,intron-Proximal	5.30001	9.51939	HepG2	IGF2BP1
chr12	12269060	12269189	-	3'-UTR,intron-Distal	5.20835	11.19402	K562	PUM2
chr12	12273523	12273549	-	3'-UTR,intron-Distal	6.08192	15.62567	HepG2	QKI
chr12	12268987	12269101	-	3'-UTR,intron-Distal	5.61592	9.77446	HepG2	FUBP3
chr12	12268996	12269060	-	3'-UTR,intron-Distal	5.12807	9.17735	K562	PUM2
chr12	12273474	12273523	-	3'-UTR,intron-Distal	4.34749	15.88626	HepG2	QKI
chr12	12273549	12273622	-	3'-UTR,intron-Distal	4.29034	8.51339	HepG2	QKI
chr12	12356271	12356333	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.24644	8.02162	HepG2	BCLAF1
chr12	12273918	12274013	-	3'-UTR,intron-Distal,intron-Proximal	5.32527	13.84968	K562	PUM2
chr12	12419646	12419712	-	5'-UTR,CDS,intron-Distal,intron-Proximal	3.61489	5.28199	HepG2	GRWD1
chr12	12419701	12419766	-	5'-UTR,intron-Distal,intron-Proximal	3.87555	23.22813	HepG2	DDX3X
chr12	12419832	12419938	-	5'-UTR,intron-Distal,intron-Proximal	3.27647	5.18023	HepG2	GRWD1
chr12	12419613	12419701	-	5'-UTR,CDS,intron-Distal	4.11094	29.65523	HepG2	DDX3X
chr12	12419856	12419935	-	5'-UTR,intron-Distal	4.54250	21.40587	HepG2	DDX3X
chr12	12419803	12419926	-	5'-UTR,intron-Distal,intron-Proximal	3.05472	6.23662	HepG2	NCBP2
chr12	12419776	12419801	-	5'-UTR,intron-Distal,intron-Proximal	4.34223	5.48791	HepG2	DDX3X
chr12	12300447	12300511	-	CDS,intron-Distal,intron-Proximal	3.47192	3.80334	HepG2	U2AF2
chr12	12301904	12302041	-	CDS,intron-Distal	3.74518	4.49887	K562	ZNF622
chr12	12300397	12300443	-	CDS,intron-Distal	3.63011	7.83567	HepG2	BCLAF1
chr12	12288201	12288305	-	CDS,intron-Distal,intron-Proximal	3.66796	5.11028	HepG2	PCBP2
chr12	12332793	12332904	-	CDS,intron-Distal	4.13460	11.91109	HepG2	BCLAF1
chr12	12311835	12311921	-	CDS,intron-Distal	3.24128	3.40321	HepG2	GRWD1
chr12	12300400	12300459	-	CDS,intron-Distal	3.05907	3.60157	HepG2	GRWD1
chr12	12300302	12300315	-	CDS,intron-Distal	3.70430	4.76554	HepG2	BCLAF1
chr12	12332742	12332806	-	CDS,intron-Distal,intron-Proximal	3.35708	3.01092	HepG2	LIN28B
chr12	12339946	12340001	-	CDS,intron-Distal,intron-Proximal	4.88295	11.54096	HepG2	BCLAF1
chr12	12356131	12356184	-	CDS,intron-Distal,intron-Proximal	4.02069	8.19556	HepG2	BCLAF1
chr12	12334039	12334129	-	CDS,intron-Distal	3.38601	4.21853	HepG2	EIF3D
chr12	12315228	12315309	-	CDS,intron-Distal	4.17027	4.50960	HepG2	GRWD1
chr12	12300435	12300506	-	CDS,intron-Distal,intron-Proximal	4.04457	3.33054	K562	U2AF1
chr12	12312773	12312820	-	CDS,intron-Distal	3.68017	6.60490	HepG2	BCLAF1
chr12	12277532	12277594	-	CDS,intron-Distal	4.24525	4.94157	HepG2	IGF2BP1
chr12	12312841	12312896	-	CDS,intron-Distal	4.04232	12.07231	HepG2	BCLAF1
chr12	12339862	12339907	-	CDS,intron-Distal	4.39502	7.97334	HepG2	BCLAF1
chr12	12397302	12397365	-	CDS,intron-Distal,intron-Proximal	3.56835	4.15543	HepG2	HLTF
chr12	12302042	12302102	-	CDS,intron-Distal,intron-Proximal	3.17411	7.22866	HepG2	U2AF2
chr12	12318178	12318228	-	CDS,intron-Distal	3.29107	5.07457	HepG2	BCLAF1
chr12	12333982	12334034	-	CDS,intron-Distal	4.03398	3.96093	HepG2	EIF3D
chr12	12318092	12318165	-	CDS,intron-Distal	3.81823	16.07427	HepG2	BCLAF1
chr12	12288224	12288296	-	CDS,intron-Distal,intron-Proximal	4.51661	8.14995	HepG2	U2AF2
chr12	12302034	12302104	-	CDS,intron-Distal,intron-Proximal	3.40164	3.75245	K562	BUD13
chr12	12315124	12315158	-	CDS,intron-Distal,intron-Proximal	4.03034	5.65086	HepG2	BCLAF1
chr12	12397418	12397490	-	CDS,intron-Distal	3.47870	7.93794	HepG2	BCLAF1
chr12	12311864	12311924	-	CDS,intron-Distal	3.43546	3.34848	HepG2	PPIG
chr12	12339862	12339937	-	CDS,intron-Distal,intron-Proximal	4.36307	5.42152	HepG2	GRWD1
chr12	12277548	12277593	-	CDS,intron-Distal	3.13011	4.61799	HepG2	BCLAF1
chr12	12276207	12276292	-	intron-Distal	3.41063	4.18806	HepG2	U2AF2
chr12	12309253	12309350	-	intron-Distal	3.26459	3.59803	HepG2	PTBP1
chr12	12418482	12418559	-	intron-Distal	4.80966	6.44072	HepG2	HNRNPM
chr12	12417886	12417976	-	intron-Distal	4.82332	6.79824	HepG2	HNRNPM
chr12	12419435	12419530	-	intron-Distal	3.15692	5.15026	HepG2	NKRF
chr12	12391377	12391442	-	intron-Distal	4.16215	3.54208	HepG2	SUGP2
chr12	12419452	12419535	-	intron-Distal	3.55681	5.32184	HepG2	PRPF4
chr12	12353024	12353089	-	intron-Distal	3.08950	3.07152	HepG2	HLTF
chr12	12395561	12395649	-	intron-Distal	3.05841	4.23271	HepG2	HNRNPM
chr12	12294015	12294150	-	intron-Distal	3.10224	3.04658	HepG2	MATR3
chr12	12340705	12340824	-	intron-Distal	4.30079	3.16986	HepG2	QKI
chr12	12418818	12418906	-	intron-Distal	3.30493	4.83226	HepG2	HNRNPM
chr12	12294104	12294154	-	intron-Distal	4.10612	3.28841	HepG2	PTBP1
chr12	12395453	12395522	-	intron-Distal	4.62853	4.90578	HepG2	HNRNPM
chr12	12419033	12419141	-	intron-Distal	3.26109	5.29774	K562	EXOSC5
chr12	12387880	12387986	-	intron-Distal	4.39768	8.88051	HepG2	PCBP2
chr12	12308490	12308562	-	intron-Distal	4.55707	5.57752	HepG2	PTBP1
chr12	12294060	12294146	-	intron-Distal	4.10060	3.18981	K562	PTBP1
chr12	12294017	12294104	-	intron-Distal	3.61480	8.88673	HepG2	PTBP1
chr12	12402578	12402633	-	intron-Distal	5.01315	5.07478	HepG2	U2AF2
chr12	12419437	12419548	-	intron-Distal	3.74329	7.96636	HepG2	FAM120A
chr12	12294023	12294148	-	intron-Distal	4.55471	10.39610	HepG2	PCBP2
chr12	12385796	12385958	-	intron-Distal	4.24767	3.62366	HepG2	HNRNPM
chr12	12284365	12284439	-	intron-Distal	5.21433	7.27974	HepG2	QKI
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

eCLIP assay for LRP6 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for LRP6 is not available on ENCORE database.
103 RBPs can affect the levels of LRP6.

The Knockdown/knockout RNA-Seq assay for LRP6 is not available on ENCORE database.

103 RBPs can affect the gene expression of LRP6 :

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
LRP6	ENSG00000070018.4	1742.06510	2570.81990	-0.56140	5.35110	4.08960	HepG2	ABCF1
LRP6	ENSG00000070018.4	1349.03840	1989.49160	-0.56050	6.21100	4.79470	HepG2	ADAR
LRP6	ENSG00000070018.4	1726.88770	2087.57020	-0.27370	3.46300	2.61610	HepG2	AKAP8L
LRP6	ENSG00000070018.4	888.93970	1607.57800	-0.85470	8.72720	7.02340	HepG2	BCCIP
LRP6	ENSG00000070018.4	1279.50050	2496.17210	-0.96410	19.29520	17.92730	HepG2	BOP1
LRP6	ENSG00000070018.4	1585.64110	2054.67610	-0.37380	4.44880	3.49970	HepG2	CALR
LRP6	ENSG00000070018.4	1605.83780	2009.00040	-0.32320	1.97810	1.31750	HepG2	CIRBP
LRP6	ENSG00000070018.4	1118.47080	2077.38450	-0.89320	34.46980	32.72280	HepG2	CKAP4
LRP6	ENSG00000070018.4	1329.19730	2040.21200	-0.61820	8.89260	7.09660	HepG2	YBX3
LRP6	ENSG00000070018.4	1557.35810	2110.16390	-0.43830	7.38100	6.42700	HepG2	CELF1
LRP6	ENSG00000070018.4	1344.70250	1921.62530	-0.51500	12.08530	10.59480	HepG2	DDX19B
LRP6	ENSG00000070018.4	926.69080	1571.09240	-0.76160	11.56990	10.29360	HepG2	DDX21
LRP6	ENSG00000070018.4	991.59690	1580.51110	-0.67260	5.67500	4.61410	HepG2	DDX55
LRP6	ENSG00000070018.4	1774.03270	2257.39020	-0.34760	2.92820	1.89020	HepG2	DDX5
LRP6	ENSG00000070018.4	1493.37460	1987.81290	-0.41260	6.81280	5.83950	HepG2	DKC1
LRP6	ENSG00000070018.4	1493.38030	2003.29770	-0.42380	6.42610	5.39110	HepG2	DNAJC21
LRP6	ENSG00000070018.4	1134.26850	1985.66270	-0.80790	28.89770	27.00750	HepG2	DNAJC2
LRP6	ENSG00000070018.4	1292.47040	1795.25890	-0.47410	2.82550	1.89550	HepG2	EEF2
LRP6	ENSG00000070018.4	1958.71700	1446.37210	0.43740	2.87350	1.74350	HepG2	AGO1
LRP6	ENSG00000070018.4	1418.86050	2021.76070	-0.51090	3.42690	2.77130	HepG2	EIF2S1
LRP6	ENSG00000070018.4	2471.61810	3429.92160	-0.47270	9.99250	8.96530	HepG2	ETF1
LRP6	ENSG00000070018.4	1562.96430	2030.40260	-0.37750	3.91240	2.91940	HepG2	EWSR1
LRP6	ENSG00000070018.4	1953.60030	1316.69630	0.56910	7.67420	6.40260	HepG2	FUBP3
LRP6	ENSG00000070018.4	1528.78180	2091.13380	-0.45190	3.22240	2.50730	HepG2	G3BP1
LRP6	ENSG00000070018.4	1736.62720	2219.57260	-0.35400	2.41270	1.58230	HepG2	G3BP2
LRP6	ENSG00000070018.4	858.30260	1297.72930	-0.59640	4.38830	3.25110	HepG2	GEMIN5
LRP6	ENSG00000070018.4	1748.99350	2597.64200	-0.57070	5.73510	4.83630	HepG2	GPKOW
LRP6	ENSG00000070018.4	1163.41890	2022.49040	-0.79780	13.86100	12.59040	HepG2	HNRNPA1
LRP6	ENSG00000070018.4	1769.89940	2249.66490	-0.34600	3.17260	2.43650	HepG2	HNRNPC
LRP6	ENSG00000070018.4	1586.53850	1902.31440	-0.26190	2.99120	2.24750	HepG2	HNRNPF
LRP6	ENSG00000070018.4	1714.18880	2478.98340	-0.53220	5.77930	4.90330	HepG2	HNRNPLL
LRP6	ENSG00000070018.4	1199.78070	2234.79010	-0.89740	30.82550	28.98610	HepG2	HNRNPU
LRP6	ENSG00000070018.4	1420.86810	1873.24010	-0.39880	4.54520	3.63720	HepG2	IGF2BP1
LRP6	ENSG00000070018.4	1482.71250	2282.76100	-0.62250	20.12960	18.36300	HepG2	ILF2
LRP6	ENSG00000070018.4	1655.22670	1899.35530	-0.19850	2.41590	1.46250	HepG2	KIF1C
LRP6	ENSG00000070018.4	2302.54110	3647.33350	-0.66360	6.52540	5.23930	HepG2	LARP4
LRP6	ENSG00000070018.4	1621.63760	2254.66130	-0.47550	3.68440	2.92820	HepG2	MAGOH
LRP6	ENSG00000070018.4	1169.84960	2267.38310	-0.95470	9.79730	8.66720	HepG2	MATR3
LRP6	ENSG00000070018.4	1812.10130	2250.02470	-0.31230	3.65780	2.78040	HepG2	NOL12
LRP6	ENSG00000070018.4	2854.17840	2198.13910	0.37670	3.46310	2.62480	HepG2	NSUN2
LRP6	ENSG00000070018.4	1423.74540	2067.27510	-0.53800	3.68330	2.85770	HepG2	PABPC4
LRP6	ENSG00000070018.4	2383.80860	1914.61030	0.31610	4.45820	3.50100	HepG2	PRPF4
LRP6	ENSG00000070018.4	1432.88390	2147.80280	-0.58390	3.94730	3.24940	HepG2	PUF60
LRP6	ENSG00000070018.4	3064.11570	2279.93750	0.42640	11.42770	10.39390	HepG2	PUM1
LRP6	ENSG00000070018.4	1341.06790	2116.26950	-0.65810	18.55780	17.21800	HepG2	PUS1
LRP6	ENSG00000070018.4	2035.31630	2866.77590	-0.49420	9.71570	8.87910	HepG2	RBM22
LRP6	ENSG00000070018.4	2978.45090	1990.66960	0.58120	9.47210	8.28000	HepG2	RBM25
LRP6	ENSG00000070018.4	1457.52930	2253.95740	-0.62890	14.69660	13.63550	HepG2	NELFE
LRP6	ENSG00000070018.4	1295.73350	2049.20710	-0.66130	9.62710	8.48010	HepG2	RPLP0
LRP6	ENSG00000070018.4	774.59870	1418.07100	-0.87240	7.87220	6.89800	HepG2	RPS19
LRP6	ENSG00000070018.4	1259.38820	1896.99030	-0.59100	6.22080	5.04830	HepG2	RPS2
LRP6	ENSG00000070018.4	1387.07250	2096.82920	-0.59620	4.62770	3.59600	HepG2	RPS3A
LRP6	ENSG00000070018.4	1501.24250	1990.16870	-0.40670	7.77560	6.77600	HepG2	SAFB2
LRP6	ENSG00000070018.4	2982.44130	2453.66710	0.28150	2.16430	1.53520	HepG2	SF3B1
LRP6	ENSG00000070018.4	2436.90500	2108.53820	0.20870	2.38640	1.83190	HepG2	SF3B4
LRP6	ENSG00000070018.4	2470.00430	2059.30530	0.26230	4.09270	3.26300	HepG2	SLBP
LRP6	ENSG00000070018.4	1667.84620	2320.85490	-0.47670	12.85480	11.62580	HepG2	SMN1
LRP6	ENSG00000070018.4	2758.94340	3237.91100	-0.23090	3.56200	3.01530	HepG2	SRFBP1
LRP6	ENSG00000070018.4	1859.22050	2120.58240	-0.18980	2.01060	1.46630	HepG2	SRSF5
LRP6	ENSG00000070018.4	1541.86150	1868.94920	-0.27760	3.28980	2.53970	HepG2	SRSF7
LRP6	ENSG00000070018.4	2048.33720	2811.26140	-0.45680	10.13680	9.27380	HepG2	SSB
LRP6	ENSG00000070018.4	1393.82050	1824.04350	-0.38810	2.32740	1.33280	HepG2	STIP1
LRP6	ENSG00000070018.4	934.67650	1753.55870	-0.90770	11.99850	10.16990	HepG2	SUPT6H
LRP6	ENSG00000070018.4	982.70020	1573.48790	-0.67910	5.92070	4.98820	HepG2	SUPV3L1
LRP6	ENSG00000070018.4	2678.23820	1978.35900	0.43690	7.38810	6.54730	HepG2	TAF15
LRP6	ENSG00000070018.4	1887.35300	2416.41020	-0.35650	3.21590	2.43980	HepG2	TARDBP
LRP6	ENSG00000070018.4	1106.90210	2171.44790	-0.97210	24.78540	23.57260	HepG2	TIAL1
LRP6	ENSG00000070018.4	1747.50550	2190.93230	-0.32620	4.91300	4.20510	HepG2	TRIM56
LRP6	ENSG00000070018.4	2630.53070	2221.14330	0.24400	1.92250	1.38820	HepG2	U2AF1
LRP6	ENSG00000070018.4	1756.99480	2220.89030	-0.33800	2.41830	1.63990	HepG2	UBE2L3
LRP6	ENSG00000070018.4	504.37080	929.58530	-0.88210	9.82000	8.39090	HepG2	UCHL5
LRP6	ENSG00000070018.4	1806.80970	2358.43980	-0.38440	7.30420	6.25920	HepG2	UPF1
LRP6	ENSG00000070018.4	787.86970	1441.13220	-0.87120	6.85740	5.23580	HepG2	UPF2
LRP6	ENSG00000070018.4	2089.22220	2424.12760	-0.21450	2.29950	1.33060	HepG2	UTP18
LRP6	ENSG00000070018.4	758.82250	1548.92280	-1.02940	14.13720	12.51750	HepG2	XRN2
LRP6	ENSG00000070018.4	1339.47900	1889.52650	-0.49640	11.28170	10.08230	HepG2	ZC3H8
LRP6	ENSG00000070018.4	1512.03650	2593.82880	-0.77860	32.28050	30.93970	HepG2	ZNF622
LRP6	ENSG00000070018.4	2202.11400	1820.03720	0.27480	3.85850	3.20780	K562	AGGF1
LRP6	ENSG00000070018.4	689.58500	879.28310	-0.35060	3.35830	2.29700	K562	BCLAF1
LRP6	ENSG00000070018.4	1548.55330	2174.96900	-0.49010	6.50320	4.66710	K562	CCDC124
LRP6	ENSG00000070018.4	1280.77660	1626.21630	-0.34450	3.25900	2.05150	K562	CPEB4
LRP6	ENSG00000070018.4	1958.03410	2397.77730	-0.29230	3.11240	2.07810	K562	CELF1
LRP6	ENSG00000070018.4	753.77420	1005.26530	-0.41540	4.45680	2.67090	K562	DDX6
LRP6	ENSG00000070018.4	741.66610	1089.11190	-0.55430	8.37220	6.24330	K562	EIF2S1
LRP6	ENSG00000070018.4	700.22000	932.88540	-0.41390	4.23840	2.75550	K562	EIF4B
LRP6	ENSG00000070018.4	689.06790	904.23370	-0.39200	3.72920	2.19630	K562	EWSR1
LRP6	ENSG00000070018.4	716.06430	1164.48330	-0.70150	4.65960	3.53900	K562	FIP1L1
LRP6	ENSG00000070018.4	791.54500	1077.28550	-0.44470	5.19910	4.40680	K562	FXR1
LRP6	ENSG00000070018.4	806.02330	1055.62680	-0.38920	3.14090	2.29770	K562	GPKOW
LRP6	ENSG00000070018.4	885.57540	1361.60280	-0.62060	7.69340	6.42030	K562	GRSF1
LRP6	ENSG00000070018.4	2793.03990	1772.97920	0.65560	3.15310	1.82430	K562	HNRNPA2B1
LRP6	ENSG00000070018.4	1133.77230	1578.91090	-0.47780	2.75910	1.96520	K562	HSPD1
LRP6	ENSG00000070018.4	2412.81790	2009.77160	0.26360	2.16270	1.44420	K562	KIF1C
LRP6	ENSG00000070018.4	985.47380	1218.08470	-0.30570	2.34240	1.56550	K562	MAGOH
LRP6	ENSG00000070018.4	942.46670	1215.64180	-0.36720	3.36820	2.33730	K562	MATR3
LRP6	ENSG00000070018.4	703.00480	1030.41480	-0.55160	5.54660	4.28000	K562	METAP2
LRP6	ENSG00000070018.4	1684.51740	2078.47280	-0.30320	2.43830	1.38040	K562	MSI2
LRP6	ENSG00000070018.4	571.32780	769.06470	-0.42880	2.66780	1.40810	K562	NONO
LRP6	ENSG00000070018.4	790.50810	1321.79670	-0.74160	5.62110	4.38170	K562	PPIG
LRP6	ENSG00000070018.4	585.56320	759.63950	-0.37550	2.17950	1.50990	K562	PRPF8
LRP6	ENSG00000070018.4	515.17540	753.57850	-0.54870	4.11460	2.98120	K562	PSIP1
LRP6	ENSG00000070018.4	916.88550	1183.43170	-0.36820	3.38050	2.65490	K562	PTBP1
LRP6	ENSG00000070018.4	1870.57940	2217.28910	-0.24530	2.62740	1.69100	K562	PUM2
LRP6	ENSG00000070018.4	2840.31870	1878.01840	0.59670	7.78170	6.91790	K562	PUS1
LRP6	ENSG00000070018.4	2301.45370	1829.98310	0.33060	3.18310	2.55440	K562	RBM15
LRP6	ENSG00000070018.4	727.40550	1134.87100	-0.64170	7.41630	5.95270	K562	RBM22
LRP6	ENSG00000070018.4	892.21500	1194.24650	-0.42060	3.32240	2.11270	K562	NELFE
LRP6	ENSG00000070018.4	898.29030	1359.83020	-0.59820	4.14200	2.89070	K562	RPS3
LRP6	ENSG00000070018.4	990.11280	1312.95800	-0.40720	2.39480	1.42480	K562	SRSF4
LRP6	ENSG00000070018.4	825.48160	1174.17900	-0.50830	4.64170	3.71850	K562	TARDBP
LRP6	ENSG00000070018.4	876.57580	1132.61650	-0.36970	3.29480	2.39030	K562	TIA1
LRP6	ENSG00000070018.4	1063.90590	1287.99030	-0.27580	2.88060	1.58400	K562	TROVE2
LRP6	ENSG00000070018.4	582.34910	778.46300	-0.41870	2.66820	1.67040	K562	UCHL5
LRP6	ENSG00000070018.4	1146.86800	1326.92380	-0.21040	1.91920	1.31280	K562	UPF1
LRP6	ENSG00000070018.4	1363.87390	1180.74670	0.20790	2.15530	1.40130	K562	WDR43
LRP6	ENSG00000070018.4	554.68780	792.64790	-0.51500	3.85920	2.34120	K562	XRN2
LRP6	ENSG00000070018.4	3047.30450	1917.69350	0.66810	3.08730	1.39030	K562	YTHDC2
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for LRP6 is not available on ENCORE database.

4 RBPs can affect the splicing of LRP6 :

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	LRP6	ENSG00000070018.4	chr12	-	12397195	12397589	12356136	12356334	12419614	12419746	-0.20200	0.00001	0.00016	excluded	HepG2	U2AF2
SE	LRP6	ENSG00000070018.4	chr12	-	12397195	12397589	12356136	12356334	12419614	12419746	-0.16800	0.00085	0.07144	excluded	HepG2	SRSF7
SE	LRP6	ENSG00000070018.4	chr12	-	12356136	12356334	12339856	12340053	12397195	12397238	-0.08200	0.00263	0.05646	excluded	K562	RBM15
A3SS	LRP6	ENSG00000070018.4	chr12	-	12288108	12288326	12288108	12288234	12291258	12291468	0.15000	0.00042	0.00323	longer	K562	AQR
A3SS	LRP6	ENSG00000070018.4	chr12	-	12334209	12334401	12334209	12334373	12336913	12337045	0.17700	0.00712	0.03939	longer	K562	AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

LRP6

General Information

Functions

Localization

Domains (AlphaFold: LRP6)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for LRP6 is not avaliable on ENCORE database.

26 proteins are bound to LRP6 RNA:

eCLIP assay for LRP6 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for LRP6 is not available on ENCORE database.

103 RBPs can affect the gene expression of LRP6 :

The Knockdown/knockout RNA-Seq assay for LRP6 is not available on ENCORE database.

4 RBPs can affect the splicing of LRP6 :

The Knockdown/knockout RNA-Seq assay for LRP6 is not avaliable on ENCORE database.