LIG1

General Information

Gene Name : LIG1
Gene ID : ENSG00000105486.13
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: LIG1)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	LIG1	ENSG00000105486.13	30.18	48.17	39.17	ENCSR000AEF
HepG2	LIG1	ENSG00000105486.13	87.41	61.52	74.47	ENCSR985KAT
K562	LIG1	ENSG00000105486.13	54.79	47.84	51.31	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for LIG1 is not avaliable on ENCORE database.

Proteins bound to RNA

LIG1 RNA is bound by 27 proteins.

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eCLIP assay for LIG1 is not avaliable on ENCORE database.

27 proteins are bound to LIG1 RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr19	48618724	48618807	-	3'-UTR,intron-Distal,intron-Proximal	5.84418	61.90633	HepG2	SUB1
chr19	48624382	48624407	-	3'-UTR,intron-Distal,intron-Proximal	6.37319	54.47238	K562	AQR
chr19	48624407	48624421	-	3'-UTR,CDS,intron-Distal,intron-Proximal	6.68137	53.05825	K562	AQR
chr19	48624421	48624427	-	CDS,intron-Distal,intron-Proximal	6.62255	51.42422	K562	AQR
chr19	48623544	48623615	-	3'-UTR,intron-Distal	5.05915	22.38149	K562	AQR
chr19	48656842	48656916	-	intron-Distal	5.82438	19.22721	K562	EIF4G2
chr19	48624382	48624428	-	3'-UTR,CDS,intron-Distal,intron-Proximal	4.28862	15.84669	HepG2	PRPF8
chr19	48664688	48664764	-	CDS,intron-Distal,intron-Proximal	4.22611	15.62408	K562	ZNF622
chr19	48634331	48634422	-	5'-UTR,CDS,intron-Distal,intron-Proximal	4.16434	13.95379	K562	UCHL5
chr19	48618727	48618786	-	3'-UTR,intron-Distal,intron-Proximal	5.10828	13.91354	K562	PABPC4
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 131 entries

eCLIP assay for LIG1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for LIG1 is not available on ENCORE database.
122 RBPs can affect the levels of LIG1.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for LIG1 is not available on ENCORE database.

122 RBPs can affect the gene expression of LIG1 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
LIG1	ENSG00000105486.9	304.45190	1289.12030	-2.08210	104.01190	101.98790	HepG2	ZNF622
LIG1	ENSG00000105486.9	463.83130	1568.42020	-1.75760	79.96450	78.23340	HepG2	SRFBP1
LIG1	ENSG00000105486.9	557.31270	1388.64670	-1.31710	38.25870	36.76820	HepG2	RBM22
LIG1	ENSG00000105486.9	188.39740	560.35900	-1.57260	31.06580	29.60240	HepG2	SRSF9
LIG1	ENSG00000105486.9	312.04900	844.08650	-1.43560	28.54680	26.60630	HepG2	CALR
LIG1	ENSG00000105486.9	1178.77940	2762.74630	-1.22880	27.62990	25.97610	K562	AQR
LIG1	ENSG00000105486.9	1420.76110	705.36640	1.01010	26.35130	25.02910	HepG2	NELFE
LIG1	ENSG00000105486.9	607.94920	1131.64710	-0.89640	19.79340	18.40840	HepG2	UTP3
LIG1	ENSG00000105486.9	1990.66440	3840.34150	-0.94800	20.56120	18.24460	K562	PUF60
LIG1	ENSG00000105486.9	653.73990	1172.13040	-0.84230	19.35320	17.82990	HepG2	UPF1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 143 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for LIG1 is not available on ENCORE database.

8 RBPs can affect the splicing of LIG1 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	LIG1	ENSG00000105486.9	chr19	-	48655113	48655151			48654488	48654596	48657128	48657224	0.14700	0.00000	0.00000	included	K562	HNRNPC
SE	LIG1	ENSG00000105486.9	chr19	-	48637237	48637323			48636238	48636354	48638936	48639036	-0.29600	0.00000	0.00000	excluded	K562	HNRNPC
A3SS	LIG1	ENSG00000105486.9	chr19	-	48631166	48631305			48631166	48631277	48634332	48634428	0.14100	0.00000	0.00000	longer	K562	AQR
A3SS	LIG1	ENSG00000105486.9	chr19	-	48640778	48641016			48640778	48640945	48643227	48643400	-0.08700	0.00002	0.02553	shorter	K562	EIF4G2
SE	LIG1	ENSG00000105486.9	chr19	-	48637237	48637323			48636238	48636354	48638936	48639036	-0.10700	0.00004	0.00076	excluded	K562	AQR
A3SS	LIG1	ENSG00000105486.9	chr19	-	48639300	48639511			48639300	48639382	48640264	48640341	0.33400	0.00004	0.03332	longer	K562	PPIL4
A3SS	LIG1	ENSG00000105486.9	chr19	-	48620894	48621079			48620894	48621038	48622393	48622447	0.07900	0.00007	0.00064	longer	K562	AQR
SE	LIG1	ENSG00000105486.9	chr19	-	48630533	48630605			48626430	48626575	48631166	48631277	-0.06600	0.00015	0.00714	excluded	K562	AKAP8L
MXE	LIG1	ENSG00000105486.9	chr19	-	48654488	48654596	48657128	48657224	48653344	48653467	48660270	48660397	0.11900	0.00023	0.02570	1included	K562	LARP4
A3SS	LIG1	ENSG00000105486.9	chr19	-	48638936	48639083			48638936	48639036	48639290	48639382	0.07600	0.00029	0.00227	longer	K562	AQR

Showing 1 to 10 of 16 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

LIG1

General Information

Functions

Localization

Domains (AlphaFold: LIG1)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for LIG1 is not avaliable on ENCORE database.

27 proteins are bound to LIG1 RNA:

eCLIP assay for LIG1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for LIG1 is not available on ENCORE database.

122 RBPs can affect the gene expression of LIG1 :

The Knockdown/knockout RNA-Seq assay for LIG1 is not available on ENCORE database.

8 RBPs can affect the splicing of LIG1 :

The Knockdown/knockout RNA-Seq assay for LIG1 is not avaliable on ENCORE database.