HPS1

General Information

Gene Name : HPS1
Gene ID : ENSG00000107521.18
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: HPS1)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	HPS1	ENSG00000107521.18	23.01	31.15	27.08	ENCSR000AEF
HepG2	HPS1	ENSG00000107521.18	23.39	14.53	18.96	ENCSR985KAT
K562	HPS1	ENSG00000107521.18	25.45	20.84	23.14	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for HPS1 is not avaliable on ENCORE database.

Proteins bound to RNA

HPS1 RNA is bound by 18 proteins.

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eCLIP assay for HPS1 is not avaliable on ENCORE database.

18 proteins are bound to HPS1 RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr10	100183366	100183503	-	CDS,intron-Distal,intron-Proximal	3.97262	13.83580	HepG2	PRPF8
chr10	100190375	100190402	-	CDS,intron-Distal	4.86905	13.47990	K562	YBX3
chr10	100190402	100190428	-	CDS,intron-Distal,intron-Proximal	4.27421	12.43828	K562	YBX3
chr10	100190267	100190373	-	CDS,intron-Distal,intron-Proximal	3.90000	11.67840	HepG2	PRPF8
chr10	100189395	100189475	-	CDS,intron-Distal,intron-Proximal	5.00970	11.52732	K562	SF3B4
chr10	100185721	100185790	-	CDS,intron-Distal,intron-Proximal	4.50789	11.33835	K562	SF3B4
chr10	100190282	100190309	-	intron-Distal,intron-Proximal	4.92110	10.24966	K562	AQR
chr10	100186961	100187025	-	CDS,intron-Distal,intron-Proximal	3.42478	10.05760	HepG2	PRPF8
chr10	100206581	100206639	-	5'-UTR,intron-Distal,intron-Proximal	5.51216	9.60748	HepG2	DDX3X
chr10	100193778	100193836	-	CDS,intron-Distal	4.08899	8.99212	K562	YBX3
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 54 entries

eCLIP assay for HPS1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for HPS1 is not available on ENCORE database.
103 RBPs can affect the levels of HPS1.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for HPS1 is not available on ENCORE database.

103 RBPs can affect the gene expression of HPS1 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
HPS1	ENSG00000107521.14	1583.63630	850.38320	0.89700	30.56540	28.53030	K562	NSUN2
HPS1	ENSG00000107521.14	699.63490	338.52500	1.04720	19.71850	18.38700	HepG2	TRIM56
HPS1	ENSG00000107521.14	2274.48400	1141.77950	0.99420	20.81300	18.29260	K562	ZC3H8
HPS1	ENSG00000107521.14	999.50240	485.44040	1.04180	17.85100	15.83620	K562	CPSF6
HPS1	ENSG00000107521.14	1257.08660	644.23590	0.96430	16.39260	15.02070	K562	HNRNPC
HPS1	ENSG00000107521.14	1259.10160	765.32900	0.71810	14.86280	13.16830	K562	MTPAP
HPS1	ENSG00000107521.14	1465.57590	647.90480	1.17750	14.23480	12.15040	K562	FIP1L1
HPS1	ENSG00000107521.14	1403.55580	901.67660	0.63830	12.68370	11.28380	K562	UPF1
HPS1	ENSG00000107521.14	1223.16510	727.94100	0.74860	13.37100	11.12140	K562	GLRX3
HPS1	ENSG00000107521.14	2837.73390	1784.97350	0.66870	12.97670	10.95530	K562	CELF1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 121 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for HPS1 is not available on ENCORE database.

22 RBPs can affect the splicing of HPS1 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	FDR	is_included	Cell Line	Affected by RBP
SE	HPS1	ENSG00000107521.14	chr10	-	100189547	100189646	100188907	100189399	100190327	100190427	0.39500	0.00001	included	K562	XRN2
SE	HPS1	ENSG00000107521.14	chr10	-	100189547	100189646	100188907	100189399	100190327	100190427	0.34100	0.00415	included	K562	GEMIN5
SE	HPS1	ENSG00000107521.14	chr10	-	100195028	100195171	100193739	100193848	100195391	100195529	-0.29000	0.00012	excluded	HepG2	HNRNPK
SE	HPS1	ENSG00000107521.14	chr10	-	100189547	100189646	100188907	100189399	100190327	100190427	0.30200	0.01627	included	K562	NONO
SE	HPS1	ENSG00000107521.14	chr10	-	100189547	100189646	100188907	100189399	100190327	100190427	0.40100	0.00000	included	K562	SUPV3L1
SE	HPS1	ENSG00000107521.14	chr10	-	100189547	100189646	100188907	100189399	100190327	100190427	0.38400	0.00008	included	K562	UCHL5
SE	HPS1	ENSG00000107521.14	chr10	-	100189547	100189646	100188907	100189399	100190327	100190427	0.30800	0.00059	included	K562	EFTUD2
SE	HPS1	ENSG00000107521.14	chr10	-	100190887	100191048	100190327	100190427	100193696	100193848	0.29000	0.00000	included	K562	HNRNPC
SE	HPS1	ENSG00000107521.14	chr10	-	100189547	100189646	100188907	100189399	100190327	100190427	-0.31600	0.00002	excluded	K562	HNRNPC
A3SS	HPS1	ENSG00000107521.14	chr10	-	100190327	100190537	100190327	100190427	100190887	100191048	0.16100	0.00001	longer	HepG2	U2AF1

Showing 1 to 10 of 27 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

HPS1

General Information

Functions

Localization

Domains (AlphaFold: HPS1)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for HPS1 is not avaliable on ENCORE database.

18 proteins are bound to HPS1 RNA:

eCLIP assay for HPS1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for HPS1 is not available on ENCORE database.

103 RBPs can affect the gene expression of HPS1 :

The Knockdown/knockout RNA-Seq assay for HPS1 is not available on ENCORE database.

22 RBPs can affect the splicing of HPS1 :

The Knockdown/knockout RNA-Seq assay for HPS1 is not avaliable on ENCORE database.