CCM2

General Information

Gene Name : CCM2
Gene ID : ENSG00000136280.16
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: CCM2)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	CCM2	ENSG00000136280.16	12.04	24.61	18.32	ENCSR000AEF
HepG2	CCM2	ENSG00000136280.16	15.92	5.97	10.95	ENCSR985KAT
K562	CCM2	ENSG00000136280.16	22.32	17.40	19.86	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for CCM2 is not avaliable on ENCORE database.

Proteins bound to RNA

CCM2 RNA is bound by 17 proteins.

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eCLIP assay for CCM2 is not avaliable on ENCORE database.

17 proteins are bound to CCM2 RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr7	45040678	45040749	+	intron-Distal	4.76568	21.64879	K562	CSTF2T
chr7	45040071	45040186	+	intron-Distal	4.35594	16.34743	K562	GTF2F1
chr7	45113166	45113223	+	3'-UTR,CDS,intron-Proximal	5.92110	10.84943	K562	AQR
chr7	45040154	45040294	+	intron-Distal	4.59805	10.75836	HepG2	CSTF2T
chr7	45040073	45040145	+	intron-Distal	4.34720	10.57219	K562	CSTF2T
chr7	45040229	45040316	+	intron-Distal	3.79294	9.67373	K562	CSTF2T
chr7	45040053	45040187	+	intron-Distal,intron-Proximal	4.28966	9.49794	HepG2	PRPF4
chr7	45040665	45040730	+	intron-Distal	5.41528	9.01569	HepG2	CSTF2
chr7	45040663	45040742	+	intron-Distal	5.98919	8.42929	K562	FMR1
chr7	45040085	45040170	+	intron-Distal	3.98203	7.18598	K562	DROSHA
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 33 entries

eCLIP assay for CCM2 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for CCM2 is not available on ENCORE database.
115 RBPs can affect the levels of CCM2.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for CCM2 is not available on ENCORE database.

115 RBPs can affect the gene expression of CCM2 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
CCM2	ENSG00000136280.11	251.79970	1173.88710	-2.22090	53.93180	51.65170	K562	AQR
CCM2	ENSG00000136280.11	439.15150	972.13650	-1.14640	31.95830	29.88880	K562	NSUN2
CCM2	ENSG00000136280.11	377.51400	874.94830	-1.21270	28.01980	25.86960	K562	MTPAP
CCM2	ENSG00000136280.11	488.01400	998.06170	-1.03220	23.30780	21.60330	K562	DDX47
CCM2	ENSG00000136280.11	111.38740	368.98020	-1.72800	22.57800	21.19550	HepG2	TAF15
CCM2	ENSG00000136280.11	473.81810	959.26500	-1.01760	20.86590	18.81120	K562	SF3A3
CCM2	ENSG00000136280.11	624.88110	1322.42280	-1.08150	20.30870	17.83480	K562	ZC3H8
CCM2	ENSG00000136280.11	412.26020	882.00260	-1.09720	18.66440	16.42280	K562	WDR3
CCM2	ENSG00000136280.11	518.53590	917.18900	-0.82280	16.56630	14.73740	K562	WDR43
CCM2	ENSG00000136280.11	529.75700	246.68840	1.10250	14.41700	13.43290	HepG2	TIAL1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 136 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for CCM2 is not available on ENCORE database.

13 RBPs can affect the splicing of CCM2 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	CCM2	ENSG00000136280.11	chr7	+	45111348	45111471			45109424	45109560	45112324	45112385	0.12100	0.00000	0.00002	included	K562	PTBP1
SE	CCM2	ENSG00000136280.11	chr7	+	45077851	45078025			45039847	45039962	45103516	45103600	0.14100	0.00002	0.01211	included	K562	PUM1
SE	CCM2	ENSG00000136280.11	chr7	+	45077851	45078025			45039786	45039962	45103516	45103600	-0.45800	0.00003	0.00103	excluded	K562	U2AF1
MXE	CCM2	ENSG00000136280.11	chr7	+	45109424	45109560	45112324	45112382	45104061	45104245	45113058	45113170	0.27700	0.00003	0.00451	1included	K562	HNRNPK
SE	CCM2	ENSG00000136280.11	chr7	+	45108041	45108178			45104061	45104245	45109424	45109560	-0.27000	0.00013	0.00336	excluded	K562	HNRNPC
MXE	CCM2	ENSG00000136280.11	chr7	+	45104061	45104245	45108041	45108178	45077851	45078025	45109424	45109560	0.23000	0.00016	0.00475	1included	K562	HNRNPC
SE	CCM2	ENSG00000136280.11	chr7	+	45111348	45111471			45109424	45109560	45112324	45112385	0.08400	0.00020	0.04769	included	K562	HNRNPA1
SE	CCM2	ENSG00000136280.11	chr7	+	45077851	45078025			45039847	45039962	45103516	45103600	0.16200	0.00058	0.06897	included	HepG2	HNRNPUL1
SE	CCM2	ENSG00000136280.11	chr7	+	45108041	45108178			45104061	45104245	45109424	45109560	-0.46000	0.00062	0.01539	excluded	K562	U2AF1
MXE	CCM2	ENSG00000136280.11	chr7	+	45104061	45104245	45109424	45109560	45077851	45078025	45112324	45112382	0.09600	0.00074	0.01620	1included	K562	PUS1

Showing 1 to 10 of 23 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

CCM2

General Information

Functions

Localization

Domains (AlphaFold: CCM2)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for CCM2 is not avaliable on ENCORE database.

17 proteins are bound to CCM2 RNA:

eCLIP assay for CCM2 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for CCM2 is not available on ENCORE database.

115 RBPs can affect the gene expression of CCM2 :

The Knockdown/knockout RNA-Seq assay for CCM2 is not available on ENCORE database.

13 RBPs can affect the splicing of CCM2 :

The Knockdown/knockout RNA-Seq assay for CCM2 is not avaliable on ENCORE database.