RRP8

General Information

Gene Name       : RRP8
Gene ID             : ENSG00000132275.10
Essential Gene : No

Functions

Localization

Domains (AlphaFold: RRP8)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878RRP8ENSG00000132275.1013.5717.7415.65ENCSR000AEF
HepG2RRP8ENSG00000132275.1010.2213.7411.98ENCSR985KAT
K562RRP8ENSG00000132275.1024.9731.8328.40ENCSR000AEO

Assays

2 Released experiments are available on ENCORE database.

Assay TypeExp_NameENCODE IDTarget labelBiosampleStatusLinked AntibodyControlsMethodNote
knockdown followed by RNA-seq BGKcLV33-11,BGKcLV33-12RRP8K562Released   CRISPRKD% = 79.3,83.0
knockdown followed by RNA-seq BGKcLV33-13,BGKcLV33-14RRP8K562Released   CRISPRKD% = 0.0,0.0






  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
RRP8K562CRISPRBGKcLV33-11,BGKcLV33-12BGKcLV33-1,BGKcLV33-279.3,83.0ReleasedENCODE4
RRP8K562CRISPRBGKcLV33-13,BGKcLV33-14BGKcLV33-1,BGKcLV33-20.0,0.0ReleasedENCODE4
RRP8K562CRISPRBGKcLV33-19,BGKcLV33-20BGKcLV33-1,BGKcLV33-20.0,0.0NotSatisfiedENCODE4
RRP8K562CRISPRBGKcLV35-61,BGKcLV35-62BGKcLV35-1,BGKcLV35-20.0,0.0NotSatisfiedENCORE2
RRP8K562CRISPRBGKcLV46-81,BGKcLV46-82BGKcLV46-1,BGKcLV46-261.8,65.9ExperimentedENCORE2
RRP8K562CRISPRBGKcLV46-83,BGKcLV46-84BGKcLV46-1,BGKcLV46-260.4,85.7ExperimentedENCORE2
RRP8HepG2CRISPRBGHcLV31-15,BGHcLV31-16BGHcLV31-1,BGHcLV31-20.0,0.0NotSatisfiedENCODE4
RRP8HepG2CRISPRBGHcLV34-43,BGHcLV34-44BGHcLV34-1,BGHcLV34-20.0,0.0NotSatisfiedENCORE2


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for RRP8 is not avaliable on ENCORE database.



Proteins bound to RNA
  • RRP8 RNA is bound by 12 proteins.  







eCLIP assay for RRP8 is not avaliable on ENCORE database.





12 proteins are bound to RRP8 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1166231776623270-3'-UTR,CDS,intron-Distal3.510744.88910K562ZNF800
chr1166226166622686-3'-UTR,CDS,intron-Distal,intron-Proximal3.913305.42720K562UCHL5
chr1166232286623277-3'-UTR,CDS,intron-Distal3.335203.65452K562BUD13
chr1166233226623351-3'-UTR,CDS,intron-Distal3.345843.36945K562ZNF622
chr1166216416621709-3'-UTR,intron-Distal,intron-Proximal4.768385.17615K562AQR
chr1166187986618819-3'-UTR,intron-Distal4.282348.17454K562UPF1
chr1166225336622593-3'-UTR,CDS,intron-Distal,intron-Proximal4.780866.19943K562RBM15
chr1166217886621870-3'-UTR,CDS,intron-Distal,intron-Proximal4.746977.04874K562EFTUD2
chr1166231356623240-3'-UTR,CDS,intron-Distal3.874908.38234K562UCHL5
chr1166231026623167-3'-UTR,CDS,intron-Distal4.676664.70478HepG2BCLAF1
chr1166187576618798-3'-UTR,intron-Distal4.656579.43510K562UPF1
chr1166216426621700-3'-UTR,intron-Distal,intron-Proximal5.169336.03057K562EFTUD2
chr1166247246624825-5'-UTR,CDS,intron-Distal,intron-Proximal3.424633.95805K562DDX3X
chr1166247086624834-5'-UTR,CDS,intron-Distal,intron-Proximal3.292383.52645HepG2NCBP2
chr1166245716624653-CDS,intron-Distal3.272433.50696K562BUD13
chr1166246116624635-CDS,intron-Distal5.162635.65342K562AQR
chr1166220176622080-intron-Distal,intron-Proximal5.227076.03057K562EFTUD2
chr1166245096624582-intron-Distal3.199063.07751K562KHSRP
chr1166245866624611-intron-Distal4.344185.26367K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for RRP8 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for RRP8 is not available on ENCORE database.

  • 27 RBPs can affect the levels of RRP8.  








The Knockdown/knockout RNA-Seq assay for RRP8 is not available on ENCORE database.





27 RBPs can affect the gene expression of RRP8 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
RRP8ENSG00000132275.6383.73060245.929700.641704.150503.43380HepG2BOP1
RRP8ENSG00000132275.6157.64320225.77970-0.518302.058101.45460HepG2CPSF6
RRP8ENSG00000132275.6487.07400313.083700.637502.637202.01210HepG2EIF4A3
RRP8ENSG00000132275.6368.73690216.418900.768703.574302.55530HepG2PABPC1
RRP8ENSG00000132275.6383.28380293.780400.383602.714802.12650HepG2PUM1
RRP8ENSG00000132275.6327.77880201.037500.705202.766502.06190HepG2RAVER1
RRP8ENSG00000132275.6267.24160339.58060-0.345601.775301.37260HepG2SRSF1
RRP8ENSG00000132275.6290.82220180.338000.689304.437803.83520HepG2TIAL1
RRP8ENSG00000132275.6433.36460286.200600.598502.979602.11280HepG2UBE2L3
RRP8ENSG00000132275.6179.27630114.497300.646802.705601.95500HepG2UCHL5
RRP8ENSG00000132275.6364.96650254.930400.517603.373102.72380HepG2UTP3
RRP8ENSG00000132275.6414.99510290.404500.514904.331603.68780HepG2ZNF622
RRP8ENSG00000132275.61202.22870934.171400.363904.245503.56860K562AGGF1
RRP8ENSG00000132275.61220.98050972.042900.328802.459101.84230K562AKAP8L
RRP8ENSG00000132275.61866.772201120.424500.7364010.362609.33630K562AQR
RRP8ENSG00000132275.61369.461101071.659700.353704.312103.52400K562DDX47
RRP8ENSG00000132275.6823.34690582.446100.499302.973401.64140K562EEF2
RRP8ENSG00000132275.6611.78140470.188300.379702.994902.16610K562EIF3G
RRP8ENSG00000132275.6774.53530593.601400.383703.417902.75500K562FXR1
RRP8ENSG00000132275.61462.661301117.073100.388803.398902.56310K562GRSF1
RRP8ENSG00000132275.6900.37760692.577400.378502.288601.44590K562HNRNPM
RRP8ENSG00000132275.61206.13310955.868400.335402.490301.71650K562PPIG
RRP8ENSG00000132275.61468.25120964.034600.606805.270604.55220K562PUS1
RRP8ENSG00000132275.61404.53090939.277600.580408.788307.75890K562RBM15
RRP8ENSG00000132275.6858.23770622.829200.462403.891002.59670K562SAFB
RRP8ENSG00000132275.6633.99490482.667300.393302.897302.07550K562U2AF2
RRP8ENSG00000132275.61078.08240888.870100.278303.036202.15100K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for RRP8 is not available on ENCORE database.





7 RBPs can affect the splicing of RRP8 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A3SSRRP8ENSG00000132275.6chr11-6621898662206166218986622005662215566225340.093000.000000.00000longerK562AQR
RIRRP8ENSG00000132275.6chr11-6622155662283266221556622285662237866228320.084000.008240.04728includedK562PUS1
RIRRP8ENSG00000132275.6chr11-6622155662283266221556622285662237866228320.142000.001140.08361includedK562NSUN2
RIRRP8ENSG00000132275.6chr11-6622155662283266221556622285662237866228320.450000.000080.00305includedK562U2AF1
RIRRP8ENSG00000132275.6chr11-6622155662283266221556622285662237866228320.079000.009790.08426includedHepG2NCBP2
RIRRP8ENSG00000132275.6chr11-6622155662283266221556622285662237866228320.119000.002210.02788includedK562UTP18
RIRRP8ENSG00000132275.6chr11-6622155662283266221556622285662237866228320.072000.010690.08413includedK562EFTUD2
RIRRP8ENSG00000132275.6chr11-6622155662283266221556622285662237866228320.233000.000000.00000includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for RRP8 is not avaliable on ENCORE database.