LGR5

General Information

Gene Name : LGR5
Gene ID : ENSG00000139292.12
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: LGR5)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	LGR5	ENSG00000139292.12	0.00	0.00	0.00	ENCSR000AEF
HepG2	LGR5	ENSG00000139292.12	42.75	66.76	54.76	ENCSR985KAT
K562	LGR5	ENSG00000139292.12	0.00	0.00	0.00	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for LGR5 is not avaliable on ENCORE database.

Proteins bound to RNA

LGR5 RNA is bound by 31 proteins.

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eCLIP assay for LGR5 is not avaliable on ENCORE database.

31 proteins are bound to LGR5 RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr12	71833673	71833732	+	5'-UTR	4.04071	38.66971	HepG2	DDX3X
chr12	71833598	71833673	+	5'-UTR	4.33625	34.74637	HepG2	DDX3X
chr12	71871484	71871601	+	intron-Distal	5.11328	33.05088	HepG2	QKI
chr12	71960791	71960866	+	intron-Distal,intron-Proximal	3.83462	23.90260	HepG2	U2AF2
chr12	71833881	71833953	+	CDS	3.35939	20.15185	HepG2	DDX3X
chr12	71960621	71960711	+	CDS,intron-Proximal	3.32394	20.12609	HepG2	BCLAF1
chr12	71898414	71898467	+	CDS,intron-Proximal	3.67779	19.58403	HepG2	PPIG
chr12	71960957	71961051	+	intron-Distal,intron-Proximal	3.07442	18.59295	HepG2	U2AF2
chr12	71833732	71833802	+	5'-UTR	3.11274	17.65870	HepG2	DDX3X
chr12	71979781	71979877	+	3'-UTR	4.79508	16.43601	HepG2	FUBP3
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 86 entries

eCLIP assay for LGR5 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for LGR5 is not available on ENCORE database.
108 RBPs can affect the levels of LGR5.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for LGR5 is not available on ENCORE database.

108 RBPs can affect the gene expression of LGR5 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
LGR5	ENSG00000139292.8	1095.16280	6088.23150	-2.47490	274.93320	272.34300	HepG2	SSB
LGR5	ENSG00000139292.8	1281.36590	5283.71020	-2.04390	99.69690	96.75830	HepG2	PUF60
LGR5	ENSG00000139292.8	978.06590	3960.29830	-2.01760	67.79790	64.56110	HepG2	U2AF1
LGR5	ENSG00000139292.8	2076.42400	3991.07620	-0.94270	56.96360	55.31350	HepG2	ZNF622
LGR5	ENSG00000139292.8	1096.08750	3595.13390	-1.71370	57.12800	54.59420	HepG2	SF3B1
LGR5	ENSG00000139292.8	791.92900	3089.04800	-1.96370	52.81740	50.63200	HepG2	SUPV3L1
LGR5	ENSG00000139292.8	4265.69090	2074.74560	1.03970	51.28780	49.32270	HepG2	RECQL
LGR5	ENSG00000139292.8	2080.13760	3995.09480	-0.94160	49.05780	46.87180	HepG2	SAFB2
LGR5	ENSG00000139292.8	3760.67090	1967.01010	0.93490	40.51740	38.68560	HepG2	PCBP1
LGR5	ENSG00000139292.8	3822.72530	2001.58920	0.93340	39.76020	38.19090	HepG2	PTBP1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 110 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for LGR5 is not available on ENCORE database.

21 RBPs can affect the splicing of LGR5 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	LGR5	ENSG00000139292.8	chr12	+	71960995	71961095			71960620	71960692	71965293	71965359	0.22500	0.00000	0.00000	included	HepG2	G3BP1
SE	LGR5	ENSG00000139292.8	chr12	+	71960995	71961095			71960620	71960692	71965293	71965359	0.34000	0.00000	0.00000	included	HepG2	HNRNPK
SE	LGR5	ENSG00000139292.8	chr12	+	71960950	71961095			71960620	71960692	71965293	71965359	0.26800	0.00000	0.00000	included	HepG2	NCBP2
SE	LGR5	ENSG00000139292.8	chr12	+	71960950	71961095			71960593	71960692	71965293	71965359	0.22600	0.00000	0.00000	included	HepG2	PCBP2
SE	LGR5	ENSG00000139292.8	chr12	+	71960995	71961095			71960620	71960692	71965293	71965359	0.23900	0.00000	0.00000	included	HepG2	IGF2BP3
MXE	LGR5	ENSG00000139292.8	chr12	+	71946852	71947068	71950398	71950470	71928894	71928966	71953365	71953434	0.13200	0.00000	0.00004	1included	HepG2	HNRNPUL1
SE	LGR5	ENSG00000139292.8	chr12	+	71955560	71955632			71953365	71953434	71960183	71960255	-0.25800	0.00001	0.00022	excluded	HepG2	U2AF2
SE	LGR5	ENSG00000139292.8	chr12	+	71960950	71961095			71960620	71960692	71965293	71965359	0.16300	0.00001	0.00474	included	HepG2	KHSRP
MXE	LGR5	ENSG00000139292.8	chr12	+	71953365	71953434	71955560	71955632	71950398	71950470	71960183	71960255	-0.10600	0.00005	0.00144	2included	HepG2	SFPQ
SE	LGR5	ENSG00000139292.8	chr12	+	71946852	71947068			71928894	71928966	71950398	71950470	0.11700	0.00014	0.04072	included	HepG2	FUBP3

Showing 1 to 10 of 28 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

LGR5

General Information

Functions

Localization

Domains (AlphaFold: LGR5)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for LGR5 is not avaliable on ENCORE database.

31 proteins are bound to LGR5 RNA:

eCLIP assay for LGR5 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for LGR5 is not available on ENCORE database.

108 RBPs can affect the gene expression of LGR5 :

The Knockdown/knockout RNA-Seq assay for LGR5 is not available on ENCORE database.

21 RBPs can affect the splicing of LGR5 :

The Knockdown/knockout RNA-Seq assay for LGR5 is not avaliable on ENCORE database.