HUWE1

General Information

Gene Name : HUWE1
Gene ID : ENSG00000086758.15
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: HUWE1)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	HUWE1	ENSG00000086758.15	93.85	101.13	97.49	ENCSR000AEF
HepG2	HUWE1	ENSG00000086758.15	70.33	64.20	67.27	ENCSR985KAT
K562	HUWE1	ENSG00000086758.15	67.50	70.11	68.81	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for HUWE1 is not avaliable on ENCORE database.

Proteins bound to RNA

HUWE1 RNA is bound by 72 proteins.

CanvasJS.com

eCLIP assay for HUWE1 is not avaliable on ENCORE database.

72 proteins are bound to HUWE1 RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chrX	53584156	53584206	-	intron-Distal	8.32904	70.68877	K562	DGCR8
chrX	53584013	53584099	-	intron-Distal	5.97036	58.97974	K562	DGCR8
chrX	53583281	53583360	-	intron-Distal	7.70349	49.09980	K562	DGCR8
chrX	53582144	53582247	-	intron-Distal	5.55922	44.23377	K562	DROSHA
chrX	53563572	53563627	-	CDS,intron-Distal,intron-Proximal	4.87479	43.43796	K562	PUM2
chrX	53610718	53610777	-	CDS,intron-Distal	5.31672	39.68031	HepG2	BCLAF1
chrX	53584155	53584209	-	intron-Distal	7.19730	33.23628	HepG2	DGCR8
chrX	53559981	53560112	-	3'-UTR,intron-Distal	4.46630	32.63491	HepG2	PCBP2
chrX	53584242	53584302	-	intron-Distal,intron-Proximal	6.24821	32.39488	K562	DGCR8
chrX	53565818	53565936	-	CDS,intron-Distal	4.27275	32.27933	HepG2	PCBP2
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 701 entries

eCLIP assay for HUWE1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for HUWE1 is not available on ENCORE database.
71 RBPs can affect the levels of HUWE1.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for HUWE1 is not available on ENCORE database.

71 RBPs can affect the gene expression of HUWE1 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
HUWE1	ENSG00000086758.11	8464.18970	14685.61270	-0.79500	20.50720	18.34200	K562	GRSF1
HUWE1	ENSG00000086758.11	4944.94820	8849.03590	-0.83960	16.89620	15.01570	K562	PRPF8
HUWE1	ENSG00000086758.11	7211.60930	10384.70660	-0.52610	14.43220	13.43750	HepG2	RBM22
HUWE1	ENSG00000086758.11	10151.11150	17034.94540	-0.74690	14.61470	12.85920	K562	HSPD1
HUWE1	ENSG00000086758.11	8390.59750	14262.83270	-0.76540	14.48520	12.13150	K562	PPIG
HUWE1	ENSG00000086758.11	8802.33030	11728.91320	-0.41410	12.72260	11.85630	HepG2	SRFBP1
HUWE1	ENSG00000086758.11	2217.74780	3573.96890	-0.68840	9.39980	8.00230	HepG2	UCHL5
HUWE1	ENSG00000086758.11	8185.54750	6185.35080	0.40410	8.43250	7.54030	HepG2	TAF15
HUWE1	ENSG00000086758.11	8600.59290	6880.97410	0.32170	8.24090	7.52430	HepG2	SRSF1
HUWE1	ENSG00000086758.11	4836.51910	6613.15070	-0.45140	7.82010	7.05720	HepG2	TIAL1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 76 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for HUWE1 is not available on ENCORE database.

32 RBPs can affect the splicing of HUWE1 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	FDR	is_included	Cell Line	Affected by RBP
SE	HUWE1	ENSG00000086758.11	chrX	-	53675515	53675593	53675154	53675253	53681006	53681075	0.09500	0.00001	included	K562	SRSF1
SE	HUWE1	ENSG00000086758.11	chrX	-	53589791	53589890	53589071	53589205	53590706	53590782	-0.30900	0.00000	excluded	K562	SRSF1
SE	HUWE1	ENSG00000086758.11	chrX	-	53589791	53589890	53589071	53589205	53590706	53590782	-0.18700	0.00000	excluded	K562	SF3B4
SE	HUWE1	ENSG00000086758.11	chrX	-	53589791	53589890	53589071	53589205	53590706	53590782	-0.16700	0.00050	excluded	K562	PRPF8
SE	HUWE1	ENSG00000086758.11	chrX	-	53589791	53589890	53589071	53589205	53590706	53590782	-0.17600	0.00000	excluded	HepG2	U2AF1
SE	HUWE1	ENSG00000086758.11	chrX	-	53589791	53589890	53589071	53589205	53590706	53590782	-0.08400	0.00000	excluded	HepG2	U2AF2
SE	HUWE1	ENSG00000086758.11	chrX	-	53589791	53589890	53589071	53589205	53590706	53590782	-0.09000	0.00000	excluded	K562	PUS1
SE	HUWE1	ENSG00000086758.11	chrX	-	53589791	53589890	53589071	53589205	53590706	53590782	-0.08600	0.00539	excluded	K562	BUD13
SE	HUWE1	ENSG00000086758.11	chrX	-	53589791	53589890	53589071	53589205	53590706	53590782	-0.19900	0.00000	excluded	K562	U2AF1
SE	HUWE1	ENSG00000086758.11	chrX	-	53589791	53589890	53589071	53589205	53590706	53590782	-0.05300	0.00021	excluded	K562	UTP18

Showing 1 to 10 of 58 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

HUWE1

General Information

Functions

Localization

Domains (AlphaFold: HUWE1)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for HUWE1 is not avaliable on ENCORE database.

72 proteins are bound to HUWE1 RNA:

eCLIP assay for HUWE1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for HUWE1 is not available on ENCORE database.

71 RBPs can affect the gene expression of HUWE1 :

The Knockdown/knockout RNA-Seq assay for HUWE1 is not available on ENCORE database.

32 RBPs can affect the splicing of HUWE1 :

The Knockdown/knockout RNA-Seq assay for HUWE1 is not avaliable on ENCORE database.