TTC6

General Information

Gene Name       : TTC6
Gene ID             : ENSG00000139865.16
Essential Gene : No

Functions

Localization

Domains (AlphaFold: TTC6)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TTC6ENSG00000139865.160.000.000.00ENCSR000AEF
HepG2TTC6ENSG00000139865.169.4310.499.96ENCSR985KAT
K562TTC6ENSG00000139865.160.100.090.10ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TTC6 is not avaliable on ENCORE database.



Proteins bound to RNA
  • TTC6 RNA is bound by 20 proteins.  







eCLIP assay for TTC6 is not avaliable on ENCORE database.





20 proteins are bound to TTC6 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr143809133738091423+3'-UTR,CDS3.584334.45064HepG2GRWD1
chr143809137438091496+3'-UTR,CDS3.532836.63189HepG2HLTF
chr143819410438194164+5'-UTR,CDS3.387673.39306HepG2GRWD1
chr143820795438208046+5'-UTR,CDS,intron-Proximal3.247893.42396HepG2U2AF2
chr143817053838170669+5'-UTR,CDS3.965116.91167HepG2GRWD1
chr143806513338065180+5'-UTR3.344334.45064HepG2GRWD1
chr143820518538205244+5'-UTR,CDS,intron-Proximal5.959986.69228HepG2PRPF8
chr143820831138208359+5'-UTR,CDS4.406388.41475HepG2BCLAF1
chr143818396738184001+5'-UTR,CDS4.011083.12746HepG2GRWD1
chr143817066938170741+5'-UTR,CDS,intron-Proximal3.944278.02029HepG2GRWD1
chr143818388238183976+5'-UTR,CDS4.4985912.53492HepG2BCLAF1
chr143826555438265575+5'-UTR,CDS,intron-Distal4.533783.89826HepG2BCLAF1
chr143820816738208216+5'-UTR,CDS3.612535.56491HepG2BCLAF1
chr143817071838170744+5'-UTR,CDS,intron-Proximal4.885595.70640HepG2BCLAF1
chr143815209138152116+CDS3.593114.09885HepG2BCLAF1
chr143822227738222349+CDS,intron-Distal,intron-Proximal3.888534.77518HepG2U2AF2
chr143809209538092165+CDS3.470997.24602HepG2GRWD1
chr143814938638149461+CDS3.911827.23562HepG2BCLAF1
chr143827385938273934+CDS,intron-Distal,intron-Proximal4.7403411.35904HepG2U2AF2
chr143814939738149466+CDS3.173684.09741HepG2PPIG
chr143821834338218415+CDS,intron-Distal4.6906110.47008HepG2BCLAF1
chr143821816638218216+CDS,intron-Distal4.998596.04243HepG2BCLAF1
chr143826603638266095+CDS,intron-Distal3.948827.23562HepG2BCLAF1
chr143825666238256719+CDS,intron-Distal,intron-Proximal3.520053.16095HepG2U2AF2
chr143826604738266192+CDS,intron-Distal,intron-Proximal3.213553.66026HepG2CDC40
chr143826609538266142+CDS,intron-Distal3.313173.55800HepG2BCLAF1
chr143809150038091597+CDS3.669565.35682HepG2GRWD1
chr143821826238218343+CDS,intron-Distal3.422595.07457HepG2BCLAF1
chr143826159138261639+CDS,intron-Distal,intron-Proximal4.799315.01842HepG2PRPF8
chr143815196138152034+CDS,intron-Proximal4.442357.53358HepG2BCLAF1
chr143822941738229518+intron-Distal3.969985.54651HepG2SUGP2
chr143824477538244834+intron-Distal3.685806.21102HepG2MATR3
chr143827402038274116+intron-Distal,intron-Proximal3.556723.81210HepG2KHSRP
chr143824723538247291+intron-Distal4.458654.64592HepG2HNRNPM
chr143821645438216546+intron-Distal3.822326.08171HepG2QKI
chr143835692438357078+intron-Distal3.886484.26114HepG2HNRNPL
chr143824744738247520+intron-Distal4.447589.76733HepG2MATR3
chr143833666438336777+intron-Distal5.6872412.86575HepG2RBFOX2
chr143823334038233408+intron-Distal3.317876.50485HepG2SUGP2
chr143822891838228970+intron-Distal4.338974.51299HepG2SUGP2
chr143824781038247882+intron-Distal3.385763.01278HepG2MATR3
chr143823259238232657+intron-Distal4.399125.04879HepG2SUGP2
chr143814428638144460+intron-Distal3.577674.77135HepG2HNRNPL
chr143824582838245880+intron-Distal4.761066.88667HepG2SUGP2
chr143825519338255256+intron-Distal4.263673.27946HepG2HNRNPM
chr143827459138274662+intron-Distal3.379924.81596HepG2HNRNPL
chr143822872738228791+intron-Distal4.470734.60209HepG2MATR3
chr143822890638228977+intron-Distal4.338784.27936HepG2PTBP1
chr143827615238276228+intron-Distal3.780456.09419HepG2KHSRP
chr143824711538247209+intron-Distal4.595444.43116HepG2RBFOX2
chr143827734738277440+intron-Distal5.190575.51162HepG2U2AF2
chr143820474938204894+intron-Distal3.511116.41380HepG2KHSRP
chr143824797238248038+intron-Distal3.870277.49312HepG2NKRF
chr143824704938247099+intron-Distal3.828504.87826HepG2MATR3
chr143822872938228797+intron-Distal4.189933.62366HepG2HNRNPM
chr143825471138254809+intron-Distal3.947586.63948HepG2MATR3
chr143832833938328410+intron-Distal4.096073.78533HepG2PTBP1
chr143825511238255163+intron-Distal4.199934.28663HepG2SUGP2
chr143823521238235284+intron-Distal3.458074.60009HepG2SUGP2
chr143832724138327368+intron-Distal6.9111116.44511HepG2PCBP2
chr143824715038247223+intron-Distal3.835259.81425HepG2SUGP2
chr143828137938281469+intron-Distal,intron-Proximal4.645023.83958HepG2QKI
chr143824729738247429+intron-Distal3.754164.18457HepG2GRSF1
chr143819556538195675+intron-Distal3.550385.90314HepG2KHSRP
chr143818500538185042+intron-Distal4.165303.45943HepG2BCLAF1
chr143824746638247524+intron-Distal4.724056.88667HepG2SUGP2
chr143810285838102918+intron-Distal3.989963.53509HepG2HLTF
chr143824752438247604+intron-Distal3.139176.78929HepG2SUGP2
chr143823109738231230+intron-Distal3.502325.14637HepG2QKI
chr143824781838247903+intron-Distal3.646475.06177HepG2SUGP2
chr143824714638247215+intron-Distal4.7555811.03373HepG2MATR3
chr143824733238247391+intron-Distal4.327926.18699HepG2MATR3
chr143818236638182482+intron-Distal3.782415.35988HepG2HNRNPL
chr143820647738206568+intron-Distal4.651456.37635HepG2HNRNPL
chr143823349938233557+intron-Distal4.353994.86548HepG2SUGP2
chr143824390238243960+intron-Distal3.297005.20425HepG2MATR3
chr143821961838219649+intron-Distal3.224054.24686HepG2CSTF2
chr143809736038097432+intron-Distal3.180033.59523HepG2SUGP2
chr143817802838178079+intron-Distal4.064403.27946HepG2HNRNPM
chr143806781438067892+intron-Distal3.171404.88713HepG2CSTF2T
chr143824630738246377+intron-Distal3.381214.36650HepG2SUGP2
chr143824731938247406+intron-Distal5.7431310.69187HepG2RBFOX2
chr143823097938231072+intron-Distal4.422025.04879HepG2SUGP2
chr143830419238304270+intron-Distal4.183804.51299HepG2SUGP2
chr143827724038277309+intron-Distal4.078263.73609HepG2KHSRP
chr143820050938200630+intron-Distal3.496727.69735HepG2HNRNPL
chr143810806038108203+intron-Distal4.878428.30933HepG2CSTF2
chr143819519838195244+intron-Distal4.664346.86842HepG2U2AF2
chr143824515538245224+intron-Distal4.472514.53347HepG2SUGP2
chr143810617738106296+intron-Distal3.782445.04128HepG2HLTF
chr143827581138275945+intron-Distal,intron-Proximal5.3315010.32854HepG2KHSRP
chr143836467138364787+intron-Distal4.565043.74583HepG2PTBP1
chr143818330838183419+intron-Distal3.492833.80334HepG2U2AF2
chr143823333438233393+intron-Distal4.470734.32882HepG2MATR3
chr143810811038108161+intron-Distal3.921296.30359HepG2QKI
chr143824512238245210+intron-Distal4.639244.66737HepG2MATR3
chr143821943838219501+intron-Distal3.280453.31157HepG2KHSRP
chr143827466238274724+intron-Distal4.478708.75025HepG2HNRNPL
chr143824447938244541+intron-Distal3.765744.36087HepG2MATR3
chr143824790438247990+intron-Distal3.258885.21690HepG2HNRNPM
chr143824744138247508+intron-Distal6.0878611.78414HepG2HNRNPM
chr143824752238247655+intron-Distal3.8448610.11399HepG2HNRNPM
chr143819339838193480+intron-Distal3.930773.39362HepG2CSTF2
chr143822889838228958+intron-Distal4.431734.66737HepG2MATR3
chr143820500038205086+intron-Distal,intron-Proximal3.034533.90086HepG2KHSRP
chr143806833838068384+intron-Distal3.163673.46580HepG2CSTF2T
chr143819426838194321+intron-Distal,intron-Proximal4.251014.02395HepG2KHSRP
chr143820094238201032+intron-Distal3.191923.33947HepG2U2AF2
chr143820317438203248+intron-Distal3.756005.82781HepG2KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TTC6 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TTC6 is not available on ENCORE database.

  • 73 RBPs can affect the levels of TTC6.  








The Knockdown/knockout RNA-Seq assay for TTC6 is not available on ENCORE database.





73 RBPs can affect the gene expression of TTC6 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TTC6ENSG00000139865.12467.13150303.112700.623903.426502.38310HepG2ABCF1
TTC6ENSG00000139865.12118.28700241.72140-1.031108.354307.41320HepG2ACO1
TTC6ENSG00000139865.12322.58760157.081601.038108.181006.57700HepG2ADAR
TTC6ENSG00000139865.1275.81230252.17220-1.7339012.1202011.08580HepG2AKAP1
TTC6ENSG00000139865.12349.21650242.832800.524103.624502.75940HepG2AKAP8L
TTC6ENSG00000139865.1288.65300139.25810-0.651502.208301.40480HepG2BCLAF1
TTC6ENSG00000139865.12258.01930356.55610-0.466702.362801.80500HepG2BOP1
TTC6ENSG00000139865.12212.18930288.86280-0.445002.226401.53040HepG2CALR
TTC6ENSG00000139865.12400.13890283.416000.497502.199801.33890HepG2CCAR1
TTC6ENSG00000139865.12593.44780327.336200.858208.139307.01190HepG2CPSF6
TTC6ENSG00000139865.12148.13850249.67430-0.753103.890502.58580HepG2CPSF7
TTC6ENSG00000139865.12183.4173098.983000.889804.037802.76450HepG2CSTF2
TTC6ENSG00000139865.12100.12030282.86740-1.4984015.5513014.27170HepG2CELF1
TTC6ENSG00000139865.12152.17170241.57380-0.666802.954302.31040HepG2DDX3X
TTC6ENSG00000139865.12111.85630207.48890-0.891404.052203.31690HepG2DDX6
TTC6ENSG00000139865.12322.51760231.254300.479802.765802.08890HepG2DKC1
TTC6ENSG00000139865.12127.12290199.49190-0.650102.465701.90450HepG2EIF2S1
TTC6ENSG00000139865.12314.81070220.475400.513802.368501.77540HepG2EIF4A3
TTC6ENSG00000139865.12443.49800300.070500.563504.326003.32270HepG2EIF4G1
TTC6ENSG00000139865.12421.25490262.606900.681704.742103.35210HepG2ESF1
TTC6ENSG00000139865.12482.15840395.074400.287301.938901.41580HepG2ETF1
TTC6ENSG00000139865.12107.21890306.08210-1.5134011.166009.76710HepG2FIP1L1
TTC6ENSG00000139865.12658.09740327.900901.004904.454403.17200HepG2FTO
TTC6ENSG00000139865.12245.36820162.941500.590502.859002.05990HepG2FUBP3
TTC6ENSG00000139865.12283.97230206.339100.460601.897301.34100HepG2G3BP1
TTC6ENSG00000139865.12420.39770219.027400.940507.478406.00360HepG2G3BP2
TTC6ENSG00000139865.12253.09150144.008800.813404.443003.29780HepG2GEMIN5
TTC6ENSG00000139865.12142.51040214.98680-0.593202.581701.60120HepG2GNB2L1
TTC6ENSG00000139865.12591.07790371.056400.671604.718903.89690HepG2GPKOW
TTC6ENSG00000139865.12165.66520230.75700-0.478102.397801.48120HepG2HDGF
TTC6ENSG00000139865.12307.28190159.692800.944206.348505.42890HepG2HNRNPA1
TTC6ENSG00000139865.12205.66980279.54510-0.442802.253501.40110HepG2HNRNPA2B1
TTC6ENSG00000139865.12289.24190177.625700.703303.728402.93300HepG2HNRNPC
TTC6ENSG00000139865.12297.76890227.270200.389702.371701.70380HepG2HNRNPF
TTC6ENSG00000139865.12352.85030223.800900.656705.312804.34200HepG2IGF2BP1
TTC6ENSG00000139865.12442.08490196.807601.167404.350403.12310HepG2IGF2BP3
TTC6ENSG00000139865.12265.80230137.951700.946105.488403.72770HepG2KHDRBS1
TTC6ENSG00000139865.12324.52580210.955200.621302.824801.81260HepG2KHSRP
TTC6ENSG00000139865.12125.15910210.65520-0.751103.848602.50300HepG2LARP7
TTC6ENSG00000139865.12582.09190361.152800.688503.617602.49920HepG2MTPAP
TTC6ENSG00000139865.12347.97910229.014800.603503.124202.45360HepG2NCBP2
TTC6ENSG00000139865.12197.30910301.64110-0.612404.041503.11990HepG2NOL12
TTC6ENSG00000139865.12675.98150313.986401.1062013.4223011.90170HepG2NSUN2
TTC6ENSG00000139865.1263.22080132.34640-1.065803.668802.63550HepG2PABPC1
TTC6ENSG00000139865.12333.86120203.977300.710704.164403.29030HepG2PABPC4
TTC6ENSG00000139865.12118.21610174.66060-0.563102.350001.56270HepG2PARN
TTC6ENSG00000139865.12402.62490242.008200.734306.881405.72440HepG2PRPF4
TTC6ENSG00000139865.12161.11940305.63450-0.923709.020008.08000HepG2PUM1
TTC6ENSG00000139865.12605.02390223.350701.4376011.7782010.62240HepG2QKI
TTC6ENSG00000139865.12172.32620330.21350-0.938307.733206.96760HepG2RBM22
TTC6ENSG00000139865.12351.44590206.277200.768604.238802.92150HepG2RCC2
TTC6ENSG00000139865.12310.19560229.511600.434502.157301.66760HepG2NELFE
TTC6ENSG00000139865.12427.42360213.757700.9996010.948909.84670HepG2RECQL
TTC6ENSG00000139865.12480.64330244.755100.9735010.037408.87360HepG2RPLP0
TTC6ENSG00000139865.12519.22450241.823101.102308.484506.90500HepG2RPS10
TTC6ENSG00000139865.12398.82070234.265500.767504.983403.92930HepG2RPS2
TTC6ENSG00000139865.12318.21140145.380701.130107.462806.16460HepG2RPS3A
TTC6ENSG00000139865.12212.71170157.139700.436801.886801.33790HepG2SAFB2
TTC6ENSG00000139865.12539.84170224.110601.2682018.8365017.83190HepG2SRSF1
TTC6ENSG00000139865.12317.74950223.269100.509003.722602.93250HepG2SRSF7
TTC6ENSG00000139865.12644.98280323.841200.9939017.0358015.98870HepG2SSB
TTC6ENSG00000139865.12312.90400156.876300.996005.255804.37090HepG2SUPV3L1
TTC6ENSG00000139865.12417.66380201.437801.0519011.7042010.67540HepG2TAF15
TTC6ENSG00000139865.12812.27320345.156601.2346018.3530016.78190HepG2TARDBP
TTC6ENSG00000139865.12551.53450277.995700.988304.598103.24600HepG2TBRG4
TTC6ENSG00000139865.12265.02490171.466900.628103.615903.06030HepG2TIAL1
TTC6ENSG00000139865.1284.88100172.98770-1.027206.337605.54680HepG2TRIM56
TTC6ENSG00000139865.12260.41720143.615800.858503.319902.21650HepG2UPF2
TTC6ENSG00000139865.12217.31500344.95800-0.666604.852604.09610HepG2UTP3
TTC6ENSG00000139865.12207.90560130.216100.674902.741801.65290HepG2XPO5
TTC6ENSG00000139865.12403.74250154.427901.3864011.5278010.06670HepG2XRN2
TTC6ENSG00000139865.12523.97220238.822001.1335018.1876016.73300HepG2ZC3H8
TTC6ENSG00000139865.12184.71090392.96010-1.0891014.1540013.15760HepG2ZNF622
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TTC6 is not available on ENCORE database.





2 RBPs can affect the splicing of TTC6 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETTC6ENSG00000139865.12chr14+3816592138166040381519623815216938170536381707310.465000.000000.00067includedHepG2TBRG4
SETTC6ENSG00000139865.12chr14+382599213826004238256672382568423826146838261619-0.532000.000160.00290excludedHepG2U2AF2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TTC6 is not avaliable on ENCORE database.