TMEM59L

General Information

Gene Name : TMEM59L
Gene ID : ENSG00000105696.8
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: TMEM59L)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	TMEM59L	ENSG00000105696.8	0.00	0.01	0.01	ENCSR000AEF
HepG2	TMEM59L	ENSG00000105696.8	17.48	3.59	10.54	ENCSR985KAT
K562	TMEM59L	ENSG00000105696.8	0.18	0.03	0.10	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for TMEM59L is not avaliable on ENCORE database.

Proteins bound to RNA

TMEM59L RNA is bound by 14 proteins.

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eCLIP assay for TMEM59L is not avaliable on ENCORE database.

14 proteins are bound to TMEM59L RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr19	18731433	18731541	+	3'-UTR	5.37403	22.38655	HepG2	PCBP2
chr19	18729108	18729231	+	CDS,intron-Proximal	3.97361	17.86547	HepG2	PRPF8
chr19	18731593	18731692	+	3'-UTR	3.96735	15.38912	HepG2	PCBP2
chr19	18719895	18719978	+	intron-Distal	6.22463	13.95507	HepG2	PCBP2
chr19	18729087	18729208	+	CDS,intron-Proximal	4.44724	12.83855	HepG2	RBFOX2
chr19	18731589	18731700	+	3'-UTR	3.67186	12.56625	HepG2	LARP4
chr19	18729113	18729177	+	intron-Proximal	4.05493	8.98325	HepG2	PPIG
chr19	18718296	18718420	+	5'-UTR,intron-Distal,intron-Proximal	4.79286	8.08697	HepG2	DDX59
chr19	18718310	18718377	+	5'-UTR,intron-Proximal	3.99452	7.96122	HepG2	CSTF2T
chr19	18731703	18731763	+	3'-UTR	4.16445	7.73571	HepG2	LARP4
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 30 entries

eCLIP assay for TMEM59L is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for TMEM59L is not available on ENCORE database.
119 RBPs can affect the levels of TMEM59L.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for TMEM59L is not available on ENCORE database.

119 RBPs can affect the gene expression of TMEM59L :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
TMEM59L	ENSG00000105696.4	32.46170	1127.91280	-5.11880	230.18630	227.72440	HepG2	SSB
TMEM59L	ENSG00000105696.4	2442.85740	297.61290	3.03700	99.00230	95.39750	HepG2	G3BP1
TMEM59L	ENSG00000105696.4	1999.22930	640.98980	1.64100	88.17280	85.66070	HepG2	SUCLG1
TMEM59L	ENSG00000105696.4	1573.55950	471.40600	1.73890	78.00980	74.48240	HepG2	HDGF
TMEM59L	ENSG00000105696.4	1287.63410	376.55670	1.77370	71.31650	69.02320	HepG2	TRIM56
TMEM59L	ENSG00000105696.4	1595.26280	563.59790	1.50100	59.30840	56.96410	HepG2	SRSF5
TMEM59L	ENSG00000105696.4	32.21650	426.97280	-3.72830	58.54590	55.97900	HepG2	SF3B1
TMEM59L	ENSG00000105696.4	914.59560	284.79640	1.68310	54.11720	52.29150	HepG2	SRSF9
TMEM59L	ENSG00000105696.4	3454.40980	548.33330	2.65520	55.10060	52.09220	HepG2	CNOT7
TMEM59L	ENSG00000105696.4	467.94170	1299.09970	-1.47310	53.24230	51.76810	HepG2	SRFBP1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 126 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for TMEM59L is not available on ENCORE database.

3 RBPs can affect the splicing of TMEM59L :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
RI	TMEM59L	ENSG00000105696.4	chr19	+	18728964	18729302	18728964	18729082	18729184	18729302	0.19700	0.00000	0.00000	included	HepG2	RBM22
SE	TMEM59L	ENSG00000105696.4	chr19	+	18727809	18727912	18726784	18726937	18728964	18729302	-0.07300	0.00050	0.05841	excluded	HepG2	SSB
RI	TMEM59L	ENSG00000105696.4	chr19	+	18728964	18729302	18728964	18729082	18729184	18729302	-0.08200	0.00138	0.09716	excluded	HepG2	DDX55

Showing 1 to 3 of 3 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

TMEM59L

General Information

Functions

Localization

Domains (AlphaFold: TMEM59L)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for TMEM59L is not avaliable on ENCORE database.

14 proteins are bound to TMEM59L RNA:

eCLIP assay for TMEM59L is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for TMEM59L is not available on ENCORE database.

119 RBPs can affect the gene expression of TMEM59L :

The Knockdown/knockout RNA-Seq assay for TMEM59L is not available on ENCORE database.

3 RBPs can affect the splicing of TMEM59L :

The Knockdown/knockout RNA-Seq assay for TMEM59L is not avaliable on ENCORE database.