TLK1

General Information

Gene Name : TLK1
Gene ID : ENSG00000198586.13
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: TLK1)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	TLK1	ENSG00000198586.13	62.83	54.40	58.61	ENCSR000AEF
HepG2	TLK1	ENSG00000198586.13	19.99	31.73	25.86	ENCSR985KAT
K562	TLK1	ENSG00000198586.13	38.60	42.51	40.55	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for TLK1 is not avaliable on ENCORE database.

Proteins bound to RNA

TLK1 RNA is bound by 52 proteins.

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eCLIP assay for TLK1 is not avaliable on ENCORE database.

52 proteins are bound to TLK1 RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr2	172016995	172017044	-	5'-UTR,intron-Distal,intron-Proximal	6.53552	400.00000	HepG2	PCBP2
chr2	172017007	172017170	-	5'-UTR,intron-Distal,intron-Proximal	5.18313	400.00000	HepG2	DDX59
chr2	172017116	172017193	-	5'-UTR,intron-Distal,intron-Proximal	7.54681	198.34980	HepG2	PCBP2
chr2	172017044	172017076	-	5'-UTR,intron-Distal,intron-Proximal	8.16523	179.08691	HepG2	PCBP2
chr2	172017098	172017116	-	5'-UTR,intron-Distal,intron-Proximal	8.23798	146.31678	HepG2	PCBP2
chr2	172017076	172017098	-	5'-UTR,intron-Distal,intron-Proximal	7.82807	145.71109	HepG2	PCBP2
chr2	171849351	171849435	-	3'-UTR,intron-Distal	4.38349	68.88693	K562	PUM2
chr2	172017080	172017203	-	5'-UTR,intron-Distal,intron-Proximal	4.50362	59.14029	K562	PCBP1
chr2	171849954	171849999	-	3'-UTR,intron-Distal,intron-Proximal	5.57566	42.68668	K562	PUM2
chr2	172016964	172017080	-	5'-UTR,intron-Distal,intron-Proximal	4.37164	41.50349	K562	PCBP1
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 284 entries

eCLIP assay for TLK1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for TLK1 is not available on ENCORE database.
62 RBPs can affect the levels of TLK1.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for TLK1 is not available on ENCORE database.

62 RBPs can affect the gene expression of TLK1 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
TLK1	ENSG00000198586.9	5089.03450	2379.40630	1.09670	38.26360	35.42150	K562	U2AF2
TLK1	ENSG00000198586.9	1423.44030	2261.46070	-0.66790	22.26910	20.54350	HepG2	HNRNPL
TLK1	ENSG00000198586.9	3671.21860	1994.36730	0.88020	16.75890	15.16270	HepG2	U2AF1
TLK1	ENSG00000198586.9	1061.11500	1586.10320	-0.57990	14.06290	12.70980	HepG2	DNAJC2
TLK1	ENSG00000198586.9	1792.00230	2704.44650	-0.59380	13.12140	12.16040	HepG2	RBM22
TLK1	ENSG00000198586.9	4141.30690	3054.55990	0.43900	11.84480	11.00100	HepG2	SRFBP1
TLK1	ENSG00000198586.9	1047.89450	1600.34550	-0.61090	11.11480	9.78190	HepG2	DNAJC21
TLK1	ENSG00000198586.9	2310.07990	3653.89280	-0.66150	12.05830	9.70610	K562	HNRNPL
TLK1	ENSG00000198586.9	1865.56070	2469.77530	-0.40480	9.69540	8.82800	HepG2	ZNF622
TLK1	ENSG00000198586.9	3466.54760	2469.24960	0.48930	8.89610	7.87350	HepG2	QKI
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 69 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for TLK1 is not available on ENCORE database.

30 RBPs can affect the splicing of TLK1 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	TLK1	ENSG00000198586.9	chr2	-	171902683	171902872			171884848	171884915	171906323	171906460	-0.11100	0.00000	0.00000	excluded	HepG2	U2AF2
SE	TLK1	ENSG00000198586.9	chr2	-	171879381	171879639			171871360	171871458	171884848	171884915	0.07600	0.00000	0.00041	included	K562	HNRNPUL1
SE	TLK1	ENSG00000198586.9	chr2	-	171879381	171879639			171871360	171871458	171884848	171884915	0.12900	0.00000	0.00014	included	K562	AGGF1
A3SS	TLK1	ENSG00000198586.9	chr2	-	171884848	171885018			171884848	171884915	171902683	171902872	0.07100	0.00000	0.00000	longer	K562	AQR
MXE	TLK1	ENSG00000198586.9	chr2	-	171879381	171879639	171884848	171884915	171871360	171871458	171902683	171902872	0.07500	0.00000	0.00014	1included	K562	FXR1
MXE	TLK1	ENSG00000198586.9	chr2	-	171939290	171939362	171974248	171974367	171917590	171917666	172016799	172017074	0.20800	0.00000	0.00077	1included	K562	TIA1
SE	TLK1	ENSG00000198586.9	chr2	-	171938149	171938218			171917590	171917666	171939290	171939362	-0.07700	0.00001	0.00488	excluded	K562	EIF4G2
SE	TLK1	ENSG00000198586.9	chr2	-	171879381	171879639			171871360	171871458	171884848	171884915	-0.10000	0.00001	0.00285	excluded	K562	RBM22
SE	TLK1	ENSG00000198586.9	chr2	-	171879381	171879639			171871360	171871458	171884848	171884915	-0.09500	0.00001	0.00110	excluded	K562	HNRNPK
SE	TLK1	ENSG00000198586.9	chr2	-	171879381	171879639			171871360	171871458	171884848	171884915	-0.10600	0.00003	0.00111	excluded	K562	SF3B4

Showing 1 to 10 of 43 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

TLK1

General Information

Functions

Localization

Domains (AlphaFold: TLK1)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for TLK1 is not avaliable on ENCORE database.

52 proteins are bound to TLK1 RNA:

eCLIP assay for TLK1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for TLK1 is not available on ENCORE database.

62 RBPs can affect the gene expression of TLK1 :

The Knockdown/knockout RNA-Seq assay for TLK1 is not available on ENCORE database.

30 RBPs can affect the splicing of TLK1 :

The Knockdown/knockout RNA-Seq assay for TLK1 is not avaliable on ENCORE database.