THOP1

General Information

Gene Name : THOP1
Gene ID : ENSG00000172009.14
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: THOP1)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	THOP1	ENSG00000172009.14	22.74	52.28	37.51	ENCSR000AEF
HepG2	THOP1	ENSG00000172009.14	115.55	47.41	81.48	ENCSR985KAT
K562	THOP1	ENSG00000172009.14	76.66	52.00	64.33	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for THOP1 is not avaliable on ENCORE database.

Proteins bound to RNA

THOP1 RNA is bound by 34 proteins.

CanvasJS.com

eCLIP assay for THOP1 is not avaliable on ENCORE database.

34 proteins are bound to THOP1 RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr19	2808197	2808267	+	CDS,intron-Proximal	5.81854	58.93607	K562	SF3B4
chr19	2813063	2813094	+	intron-Distal,intron-Proximal	5.14913	25.82224	K562	SF3B4
chr19	2813094	2813122	+	CDS,intron-Distal,intron-Proximal	5.43587	25.53498	K562	SF3B4
chr19	2808197	2808282	+	CDS,intron-Proximal	5.08544	25.15618	HepG2	SF3B4
chr19	2802531	2802627	+	intron-Distal	6.69363	25.00481	K562	AGGF1
chr19	2807810	2807847	+	intron-Proximal	4.66604	21.98818	K562	AQR
chr19	2808167	2808263	+	CDS,intron-Proximal	4.27833	19.91098	HepG2	EFTUD2
chr19	2807804	2807810	+	CDS,intron-Proximal	4.36290	17.52944	K562	AQR
chr19	2810481	2810556	+	CDS,intron-Proximal	4.50219	14.59055	HepG2	PRPF8
chr19	2808170	2808268	+	CDS,intron-Proximal	4.56647	14.46261	HepG2	PRPF8
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 171 entries

eCLIP assay for THOP1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for THOP1 is not available on ENCORE database.
103 RBPs can affect the levels of THOP1.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for THOP1 is not available on ENCORE database.

103 RBPs can affect the gene expression of THOP1 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
THOP1	ENSG00000172009.10	2171.22970	3882.76830	-0.83860	23.64010	21.19460	K562	CELF1
THOP1	ENSG00000172009.10	466.15320	1032.92890	-1.14790	21.43190	20.07790	HepG2	TAF15
THOP1	ENSG00000172009.10	557.05860	1178.50540	-1.08110	19.67780	18.16820	K562	HNRNPC
THOP1	ENSG00000172009.10	1036.85030	2261.68640	-1.12520	19.05110	17.67630	K562	AQR
THOP1	ENSG00000172009.10	1106.90550	644.47480	0.78020	16.27440	15.06180	HepG2	TRIM56
THOP1	ENSG00000172009.10	1238.65240	2008.56630	-0.69740	15.51260	13.69670	K562	SF3A3
THOP1	ENSG00000172009.10	1138.29850	1735.98540	-0.60890	14.25970	13.35760	HepG2	SRFBP1
THOP1	ENSG00000172009.10	1463.05070	988.09520	0.56620	13.90820	12.79240	HepG2	PUM1
THOP1	ENSG00000172009.10	1216.07100	1839.00020	-0.59670	12.93310	11.79070	HepG2	ETF1
THOP1	ENSG00000172009.10	1337.86670	760.51130	0.81480	13.63380	11.69580	K562	TIA1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 117 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for THOP1 is not available on ENCORE database.

9 RBPs can affect the splicing of THOP1 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
RI	THOP1	ENSG00000172009.10	chr19	+	2807439	2808442			2807439	2807806	2808240	2808442	-0.49600	0.00013	0.02086	excluded	K562	XRN2
MXE	THOP1	ENSG00000172009.10	chr19	+	2790418	2790631	2794761	2794910	2785457	2785676	2796078	2796186	0.14700	0.00015	0.00788	1included	K562	UCHL5
RI	THOP1	ENSG00000172009.10	chr19	+	2807439	2808442			2807439	2807806	2808240	2808442	-0.49000	0.00056	0.05467	excluded	K562	UCHL5
MXE	THOP1	ENSG00000172009.10	chr19	+	2790418	2790631	2794761	2794910	2785457	2785676	2796078	2796186	0.12700	0.00066	0.04589	1included	K562	TRA2A
RI	THOP1	ENSG00000172009.10	chr19	+	2807439	2808442			2807439	2807806	2808240	2808442	-0.49100	0.00092	0.06328	excluded	K562	NONO
RI	THOP1	ENSG00000172009.10	chr19	+	2807439	2808442			2807439	2807806	2808240	2808442	0.33100	0.00096	0.00899	included	HepG2	SF3B4
RI	THOP1	ENSG00000172009.10	chr19	+	2807439	2808442			2807439	2807806	2808240	2808442	0.24900	0.00160	0.07373	included	K562	NPM1
RI	THOP1	ENSG00000172009.10	chr19	+	2807439	2808442			2807439	2807806	2808240	2808442	0.38900	0.00234	0.03938	included	HepG2	FUBP3
RI	THOP1	ENSG00000172009.10	chr19	+	2807439	2808442			2807439	2807806	2808240	2808442	0.22600	0.00263	0.03063	included	K562	AGGF1
RI	THOP1	ENSG00000172009.10	chr19	+	2807439	2808442			2807439	2807806	2808240	2808442	0.18200	0.01044	0.05834	included	K562	PUS1

Showing 1 to 10 of 10 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

THOP1

General Information

Functions

Localization

Domains (AlphaFold: THOP1)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for THOP1 is not avaliable on ENCORE database.

34 proteins are bound to THOP1 RNA:

eCLIP assay for THOP1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for THOP1 is not available on ENCORE database.

103 RBPs can affect the gene expression of THOP1 :

The Knockdown/knockout RNA-Seq assay for THOP1 is not available on ENCORE database.

9 RBPs can affect the splicing of THOP1 :

The Knockdown/knockout RNA-Seq assay for THOP1 is not avaliable on ENCORE database.