NR1H3

General Information

Gene Name       : NR1H3
Gene ID             : ENSG00000025434.18
Essential Gene : No

Functions

Localization

Domains (AlphaFold: NR1H3)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878NR1H3ENSG00000025434.180.171.760.96ENCSR000AEF
HepG2NR1H3ENSG00000025434.1829.2019.3524.27ENCSR985KAT
K562NR1H3ENSG00000025434.1810.998.059.52ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for NR1H3 is not avaliable on ENCORE database.



Proteins bound to RNA
  • NR1H3 RNA is bound by 12 proteins.  







eCLIP assay for NR1H3 is not avaliable on ENCORE database.





12 proteins are bound to NR1H3 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr114728276747282863+3'-UTR,CDS,intron-Distal,intron-Proximal3.197543.60559HepG2AQR
chr114728126747281352+3'-UTR,CDS,intron-Distal,intron-Proximal4.308214.24670HepG2SF3B4
chr114728133047281388+3'-UTR,CDS,intron-Distal,intron-Proximal3.847414.13746HepG2PPIG
chr114728130947281398+3'-UTR,CDS,intron-Distal,intron-Proximal3.461518.46496HepG2BUD13
chr114728133547281531+3'-UTR,CDS,intron-Distal,intron-Proximal3.640574.77549HepG2PABPN1
chr114728210247282201+3'-UTR,CDS,intron-Distal3.546953.63043HepG2GRWD1
chr114727966547279720+5'-UTR,intron-Distal,intron-Proximal3.884763.56873HepG2PRPF8
chr114728328447283389+CDS,intron-Distal,intron-Proximal4.090386.08301HepG2EFTUD2
chr114728948247289534+CDS3.686454.13746HepG2PPIG
chr114728311147283275+CDS,intron-Distal3.741925.11891HepG2GRWD1
chr114728091047281014+CDS,intron-Distal,intron-Proximal3.012193.00437HepG2HNRNPK
chr114728298647283037+CDS,intron-Distal,intron-Proximal5.541814.35676HepG2PRPF8
chr114727935947279440+intron-Distal,intron-Proximal4.136643.63122HepG2PRPF4
chr114727937847279471+intron-Distal,intron-Proximal3.993903.71028HepG2NKRF
chr114727721247277280+intron-Distal3.707264.78196HepG2PTBP1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for NR1H3 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for NR1H3 is not available on ENCORE database.

  • 76 RBPs can affect the levels of NR1H3.  








The Knockdown/knockout RNA-Seq assay for NR1H3 is not available on ENCORE database.





76 RBPs can affect the gene expression of NR1H3 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
NR1H3ENSG00000025434.14362.73250484.56000-0.417803.346802.68830HepG2ACO1
NR1H3ENSG00000025434.14595.22900773.78660-0.378501.937601.48340HepG2AKAP1
NR1H3ENSG00000025434.14360.31660486.76130-0.433903.024002.22560HepG2AKAP8L
NR1H3ENSG00000025434.14618.90870746.58640-0.270602.020801.41700HepG2AUH
NR1H3ENSG00000025434.14519.44340346.759000.582903.987703.17580HepG2CPSF6
NR1H3ENSG00000025434.14602.70120497.215200.277501.875101.32720HepG2CELF1
NR1H3ENSG00000025434.14752.51280534.604200.493106.334905.28000HepG2DAZAP1
NR1H3ENSG00000025434.14412.36550291.739100.499102.998202.29490HepG2DDX21
NR1H3ENSG00000025434.14443.44750285.737500.634004.720903.45390HepG2DHX30
NR1H3ENSG00000025434.14478.46290296.258000.691506.794705.73150HepG2DNAJC21
NR1H3ENSG00000025434.14367.92720293.628500.325301.937901.37450HepG2DNAJC2
NR1H3ENSG00000025434.14477.89570658.62420-0.462802.214701.59600HepG2EIF4B
NR1H3ENSG00000025434.14572.67590857.23720-0.582007.652806.73720HepG2ETF1
NR1H3ENSG00000025434.14307.88030473.42140-0.620804.940803.82710HepG2EWSR1
NR1H3ENSG00000025434.14415.02420568.65940-0.454402.237601.54140HepG2FIP1L1
NR1H3ENSG00000025434.14613.48830466.446800.395202.535101.78130HepG2FUBP3
NR1H3ENSG00000025434.14436.09660332.684600.390401.927901.33730HepG2HNRNPC
NR1H3ENSG00000025434.14390.31490486.97610-0.319202.092901.49590HepG2HNRNPL
NR1H3ENSG00000025434.14492.84990375.102500.393801.944201.40800HepG2HNRNPLL
NR1H3ENSG00000025434.14499.79710375.093500.414002.472301.78670HepG2IGF2BP1
NR1H3ENSG00000025434.14433.95350643.45700-0.568304.000403.20230HepG2IGF2BP2
NR1H3ENSG00000025434.14293.16300604.06380-1.043003.646702.51650HepG2IGF2BP3
NR1H3ENSG00000025434.14386.63690583.16630-0.592903.429002.50300HepG2LARP4
NR1H3ENSG00000025434.14329.61520686.62700-1.0587010.531509.35980HepG2MATR3
NR1H3ENSG00000025434.14438.71600702.76450-0.679805.427304.55430HepG2NCBP2
NR1H3ENSG00000025434.14185.32920272.64000-0.556902.470901.70580HepG2PRPF8
NR1H3ENSG00000025434.14543.25450664.39970-0.290402.248701.74570HepG2PTBP1
NR1H3ENSG00000025434.14715.20050493.542600.535106.538305.66260HepG2PUS1
NR1H3ENSG00000025434.14175.10350314.81800-0.846303.575202.77620HepG2RAVER1
NR1H3ENSG00000025434.14700.88380527.909500.408803.313702.38450HepG2RBM15
NR1H3ENSG00000025434.14396.84320716.47990-0.8524011.7228010.81030HepG2RBM22
NR1H3ENSG00000025434.14412.63270653.05460-0.662306.470605.48010HepG2RBM25
NR1H3ENSG00000025434.14478.20610739.41780-0.628807.652906.83340HepG2NELFE
NR1H3ENSG00000025434.14456.93580688.65860-0.591806.740005.83880HepG2RECQL
NR1H3ENSG00000025434.14165.74220269.69220-0.702403.329302.47690HepG2RRP9
NR1H3ENSG00000025434.14418.05270294.314500.506203.095002.42080HepG2SAFB2
NR1H3ENSG00000025434.14284.52790487.39690-0.776505.204804.26200HepG2SF3A3
NR1H3ENSG00000025434.14232.33790371.26440-0.676204.301003.43900HepG2SF3B1
NR1H3ENSG00000025434.14484.66540691.73610-0.513203.659202.99260HepG2SF3B4
NR1H3ENSG00000025434.14586.14660485.236000.272501.981701.37010HepG2SLBP
NR1H3ENSG00000025434.14345.15670809.21710-1.2293027.8531026.69540HepG2SRFBP1
NR1H3ENSG00000025434.14320.61660722.01860-1.1712021.3819020.32940HepG2SRSF1
NR1H3ENSG00000025434.14257.50270399.51870-0.633703.119802.04730HepG2SRSF3
NR1H3ENSG00000025434.14471.43530587.39690-0.317302.417901.89490HepG2SRSF9
NR1H3ENSG00000025434.14474.60960692.37360-0.544803.851502.35740HepG2SSRP1
NR1H3ENSG00000025434.14490.18850700.80950-0.515702.982501.60440HepG2SUGP2
NR1H3ENSG00000025434.14371.33450648.96680-0.8054010.355009.38080HepG2TAF15
NR1H3ENSG00000025434.14482.30610321.145000.586604.906104.27910HepG2TIAL1
NR1H3ENSG00000025434.14529.75510323.997900.709208.543407.63860HepG2TRIM56
NR1H3ENSG00000025434.14328.30210486.43210-0.567203.549902.84310HepG2U2AF1
NR1H3ENSG00000025434.14478.59410322.177100.570802.332601.41730HepG2UPF2
NR1H3ENSG00000025434.14568.93780355.134100.679804.357402.97340HepG2XPO5
NR1H3ENSG00000025434.14259.82050439.42100-0.758108.276407.21910HepG2ZC3H8
NR1H3ENSG00000025434.1486.37440149.58730-0.792303.199902.59720K562AGGF1
NR1H3ENSG00000025434.1499.89470155.65000-0.639802.070301.50290K562AKAP8L
NR1H3ENSG00000025434.14281.52040178.772500.655003.837202.41820K562CCDC124
NR1H3ENSG00000025434.14259.13550351.41540-0.439502.580901.63900K562CELF1
NR1H3ENSG00000025434.14158.28360223.53360-0.498002.344101.73650K562DDX47
NR1H3ENSG00000025434.14364.57540101.787501.8406022.7313020.12350K562EIF4A3
NR1H3ENSG00000025434.14211.57010285.71690-0.433502.533301.62950K562EIF4G2
NR1H3ENSG00000025434.14366.12880235.703700.635303.856902.97050K562GRSF1
NR1H3ENSG00000025434.1489.51430197.64820-1.142703.523302.09190K562HNRNPA2B1
NR1H3ENSG00000025434.14185.43150113.725300.705202.819201.87920K562HNRNPM
NR1H3ENSG00000025434.14147.05800216.65110-0.559002.634901.76310K562HNRNPU
NR1H3ENSG00000025434.14299.52430187.425800.676303.754802.83300K562HSPD1
NR1H3ENSG00000025434.14185.06000120.656100.617002.755501.91730K562MAGOH
NR1H3ENSG00000025434.14173.70470117.285900.566502.067501.30950K562METAP2
NR1H3ENSG00000025434.1474.84780129.70960-0.793302.261801.48400K562NAA15
NR1H3ENSG00000025434.1458.57580107.33680-0.873802.708201.73950K562PCBP2
NR1H3ENSG00000025434.14132.31500229.84560-0.796703.797802.82350K562PCBP3
NR1H3ENSG00000025434.1494.37410176.29560-0.901504.546903.51690K562POLR2G
NR1H3ENSG00000025434.14201.95130311.72500-0.626303.285402.39730K562PUF60
NR1H3ENSG00000025434.14221.19510331.66620-0.584404.009802.70390K562PUM1
NR1H3ENSG00000025434.1486.09110154.37870-0.842503.527102.92560K562PUS1
NR1H3ENSG00000025434.1492.95130181.67010-0.966802.668101.47030K562SNRNP200
NR1H3ENSG00000025434.14107.97760217.37480-1.009503.088901.55470K562SUPT6H
NR1H3ENSG00000025434.14224.62380116.300900.949504.714903.78380K562TARDBP
NR1H3ENSG00000025434.14165.27680112.191400.558802.028801.33480K562TIA1
NR1H3ENSG00000025434.14292.23740211.091800.469202.715302.00270K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for NR1H3 is not available on ENCORE database.





12 RBPs can affect the splicing of NR1H3 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SENR1H3ENSG00000025434.14chr11+472807304728081047279548472796804728134147281530-0.583000.001110.02246excludedHepG2U2AF1
SENR1H3ENSG00000025434.14chr11+4728091147281157472807304728081047281341472813740.254000.002350.05341includedHepG2HNRNPK
SENR1H3ENSG00000025434.14chr11+4728091147281157472807304728081047281341472813740.205000.001050.03195includedHepG2SF3A3
A5SSNR1H3ENSG00000025434.14chr11+4727046647270654472704664727055047281341472815300.192000.001750.09539longerHepG2HNRNPK
RINR1H3ENSG00000025434.14chr11+4728309747283569472830974728327747283469472835690.211000.000000.00022includedHepG2PCBP2
RINR1H3ENSG00000025434.14chr11+4728309747283569472830974728327747283469472835690.077000.000010.00010includedHepG2U2AF2
RINR1H3ENSG00000025434.14chr11+4728309747283569472830974728327747283469472835690.155000.000100.06564includedHepG2YBX3
RINR1H3ENSG00000025434.14chr11+4728309747283569472830974728327747283469472835690.098000.011370.09424includedHepG2QKI
RINR1H3ENSG00000025434.14chr11+4728309747283569472830974728327747283469472835690.412000.000210.00703includedK562RBM22
RINR1H3ENSG00000025434.14chr11+4728309747283569472830974728327747283469472835690.147000.000710.00902includedHepG2TAF15
RINR1H3ENSG00000025434.14chr11+4728309747283569472830974728327747283469472835690.218000.000000.00008includedHepG2SF3B4
RINR1H3ENSG00000025434.14chr11+4728309747283569472830974728327747283469472835690.337000.000000.00000includedHepG2RBM22
RINR1H3ENSG00000025434.14chr11+4728309747283569472830974728327747283469472835690.151000.000730.01433includedHepG2SRSF9
RINR1H3ENSG00000025434.14chr11+472830974728356947283097472832774728346947283569-0.135000.000540.04438excludedK562FMR1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for NR1H3 is not avaliable on ENCORE database.