MNAT1

General Information

Gene Name       : MNAT1
Gene ID             : ENSG00000020426.10
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: MNAT1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MNAT1ENSG00000020426.1032.4932.2632.38ENCSR000AEF
HepG2MNAT1ENSG00000020426.1032.4857.8045.14ENCSR985KAT
K562MNAT1ENSG00000020426.1037.9140.6039.25ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
MNAT1Ribo-STAMP-293TshRNAMNAT1-BGRSLV02-29,MNAT1-BGRSLV02-30NT-BGRSLV02-1,NT-BGRSLV02-2,SubmittedENCORE2


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MNAT1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • MNAT1 RNA is bound by 20 proteins.  







eCLIP assay for MNAT1 is not avaliable on ENCORE database.





20 proteins are bound to MNAT1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr146120151361201603+5'-UTR,CDS3.067543.23234HepG2EIF3D
chr146120149361201632+5'-UTR,CDS3.256047.98234K562DDX3X
chr146120150961201673+5'-UTR,CDS,intron-Proximal3.069434.85577K562ZNF622
chr146127504261275128+CDS,intron-Proximal3.650825.10069HepG2GRWD1
chr146126296461263019+CDS,intron-Distal3.776504.93978HepG2BCLAF1
chr146128543861285564+CDS,intron-Distal,intron-Proximal3.867778.94272HepG2GRWD1
chr146127872261278824+CDS5.2043011.13876HepG2BCLAF1
chr146128543761285536+CDS,intron-Distal,intron-Proximal3.7624211.53232HepG2BCLAF1
chr146127870061278830+CDS,intron-Proximal3.041123.62355K562HLTF
chr146126293461263018+CDS,intron-Distal,intron-Proximal4.452014.45558HepG2GRWD1
chr146127882761278855+CDS,intron-Proximal3.998598.94445HepG2BCLAF1
chr146127872161278801+CDS4.105256.14226K562ZNF622
chr146143494061435009+CDS,intron-Distal,intron-Proximal3.936385.99890HepG2U2AF2
chr146128548261285553+CDS,intron-Distal3.160224.03389K562ZNF622
chr146134643061346567+CDS,intron-Proximal3.650827.44807HepG2GRWD1
chr146128543861285482+CDS,intron-Distal,intron-Proximal3.022404.14618K562ZNF622
chr146126304061263085+CDS,intron-Distal3.533783.57857HepG2BCLAF1
chr146127880161278847+CDS,intron-Proximal3.568364.49887K562ZNF622
chr146127980361279920+intron-Distal5.283838.04247HepG2LSM11
chr146138124361381286+intron-Distal3.118183.35050HepG2SUGP2
chr146129475261294868+intron-Distal3.931033.24603K562KHSRP
chr146137767961377726+intron-Distal4.507023.01445K562EXOSC5
chr146142722361427323+intron-Distal3.256893.54383HepG2HNRNPL
chr146120168161201815+intron-Distal,intron-Proximal3.656963.15816HepG2PRPF4
chr146135264661352701+intron-Distal3.875504.91094K562EXOSC5
chr146142750461427573+intron-Distal3.101684.63615HepG2HNRNPL
chr146138238761382464+intron-Distal4.482415.02084HepG2HNRNPM
chr146130036561300447+intron-Distal4.6117510.29529K562EXOSC5
chr146123090861230981+intron-Distal4.561216.58261K562KHSRP
chr146133952561339584+intron-Distal4.038135.03298HepG2HNRNPL
chr146122859861228681+intron-Distal3.230683.81210HepG2KHSRP
chr146135299461353026+intron-Distal3.728783.16028HepG2SUGP2
chr146136069861360756+intron-Distal3.068415.43131HepG2SUGP2
chr146136070561360748+intron-Distal3.878413.27946HepG2HNRNPM
chr146134128761341342+intron-Distal4.573034.67693K562PTBP1
chr146140481861404864+intron-Distal4.177543.01445K562EXOSC5
chr146135250761352567+intron-Distal4.666026.32237HepG2SUGP2
chr146130788261307984+intron-Distal3.328503.10961HepG2MATR3
chr146130614661306265+intron-Distal4.483255.83017HepG2LSM11
chr146141326961413346+intron-Distal4.465013.96879HepG2MATR3
chr146130037261300456+intron-Distal4.265933.07980HepG2HNRNPM
chr146141482561414893+intron-Distal3.058033.00129HepG2SUGP2
chr146120194261202165+intron-Distal5.022738.24653K562KHSRP
chr146134982761349853+intron-Distal3.270423.94919HepG2HNRNPM
chr146136033361360387+intron-Distal3.457214.35402HepG2SUGP2
chr146133966361339753+intron-Distal4.787956.64534HepG2HNRNPL
chr146120706161207114+intron-Distal3.775524.19039HepG2PTBP1
chr146121143761211513+intron-Distal3.472513.59523HepG2SUGP2
chr146135100561351082+intron-Distal3.222475.12506HepG2SUGP2
chr146121128561211341+intron-Distal3.118183.35050HepG2SUGP2
chr146138233361382425+intron-Distal3.368816.55984HepG2SUGP2
chr146135078761350941+intron-Distal3.907276.18699HepG2MATR3
chr146136457561364710+intron-Distal4.3221717.81764HepG2QKI
chr146127638361276444+intron-Distal3.749743.24603K562KHSRP
chr146133959161339638+intron-Distal4.003723.27714HepG2HNRNPL
chr146121188161211955+intron-Distal3.012314.24063HepG2SUGP2
chr146131617961316279+intron-Distal3.714913.06150K562KHSRP
chr146122599861226060+intron-Distal3.616373.95921HepG2U2AF2
chr146131282061312914+intron-Distal4.1122011.72005HepG2PTBP1
chr146121992161219990+intron-Distal3.805693.24590HepG2ILF3
chr146141253761412637+intron-Distal3.274005.38424HepG2HNRNPL
chr146138236461382442+intron-Distal3.738755.28137HepG2MATR3
chr146140199161402090+intron-Distal4.5899013.53114HepG2PCBP2
chr146135941761359508+intron-Distal4.068534.54401K562KHSRP
chr146135245961352547+intron-Distal4.823866.43853HepG2MATR3
chr146122848561228580+intron-Distal3.957293.55754HepG2U2AF2
chr146129937561299504+intron-Distal5.119078.69493K562EXOSC5
chr146134126561341287+intron-Distal3.644333.76275K562PTBP1
chr146131300161313073+intron-Distal3.054283.33633HepG2MATR3
chr146136059561360665+intron-Distal4.6749613.65884HepG2SUGP2
chr146135222461352275+intron-Distal3.159983.10961HepG2MATR3
chr146135246861352490+intron-Distal4.014993.30687K562EXOSC5
chr146131281961312935+intron-Distal4.123255.38389HepG2PCBP2
chr146130620061306324+intron-Distal3.807944.93068K562LSM11
chr146130073361300815+intron-Distal4.606975.37222HepG2MATR3
chr146123840561238481+intron-Distal3.518663.89405HepG2PTBP1
chr146135232961352361+intron-Distal3.118213.14999K562EXOSC5
chr146136070061360743+intron-Distal4.145233.27829HepG2MATR3
chr146140706761407094+intron-Distal3.566604.02190K562EXOSC5
chr146141266961412743+intron-Distal4.714105.39754HepG2HNRNPL
chr146134126961341286+intron-Distal4.953847.45191HepG2PTBP1
chr146129938061299510+intron-Distal3.339723.97110HepG2MATR3
chr146140597161406020+intron-Distal3.903793.01445K562EXOSC5
chr146142690761426995+intron-Distal3.309495.83578HepG2SUGP2
chr146140709461407145+intron-Distal3.391365.02053K562EXOSC5
chr146140595261406052+intron-Distal4.208003.62238HepG2MATR3
chr146121132761211402+intron-Distal3.270423.39857HepG2HNRNPM
chr146126488661264999+intron-Distal,intron-Proximal4.234654.21433K562PRPF8
chr146137723261377320+intron-Distal4.007023.01456K562EXOSC5
chr146136456161364657+intron-Distal4.622368.98522K562QKI
chr146135212861352175+intron-Distal4.265554.51299HepG2SUGP2
chr146134128661341352+intron-Distal5.6500012.63599HepG2PTBP1
chr146136076861360814+intron-Distal4.207254.53347HepG2SUGP2
chr146120209061202166+intron-Distal4.556725.10338HepG2KHSRP
chr146134892261349019+intron-Distal4.2190015.40627HepG2PCBP2
chr146136043461360511+intron-Distal3.435285.42643HepG2MATR3
chr146130784661307976+intron-Distal4.9271512.24240HepG2PTBP1
chr146138219161382262+intron-Distal3.372255.12506HepG2SUGP2
chr146136140961361462+intron-Distal3.497304.08528HepG2SUGP2
chr146135263361352710+intron-Distal3.297005.20425HepG2MATR3
chr146135694461357017+intron-Distal3.212054.02525HepG2HLTF
chr146130138461301428+intron-Distal4.182983.78432HepG2MATR3
chr146129875361298807+intron-Distal4.167983.89080K562EXOSC5
chr146134123861341269+intron-Distal3.909343.09122HepG2PTBP1
chr146120975761209894+intron-Distal5.100668.59433HepG2MATR3
chr146136675261366829+intron-Distal3.705094.19039HepG2PTBP1
chr146130036361300439+intron-Distal4.151734.53347HepG2SUGP2
chr146127979861279946+intron-Distal5.360878.27592K562LSM11
chr146130266461302702+intron-Distal3.381963.39827HepG2MATR3
chr146121135561211437+intron-Distal4.042188.18586HepG2SUGP2
chr146136057661360646+intron-Distal3.657067.24444HepG2MATR3
chr146134891861349027+intron-Distal4.5136918.76892HepG2QKI
chr146142322161423304+intron-Distal3.100095.10681HepG2SUGP2
chr146141268161412804+intron-Distal3.300133.51714HepG2QKI
chr146136066561360698+intron-Distal3.053544.61989HepG2SUGP2
chr146143373261433791+intron-Distal5.312538.61026HepG2U2AF2
chr146130786161308007+intron-Distal5.568337.91717K562PTBP1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MNAT1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MNAT1 is not available on ENCORE database.

  • 72 RBPs can affect the levels of MNAT1.  








The Knockdown/knockout RNA-Seq assay for MNAT1 is not available on ENCORE database.





72 RBPs can affect the gene expression of MNAT1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MNAT1ENSG00000020426.6400.23070492.65860-0.299801.985501.45440HepG2ACO1
MNAT1ENSG00000020426.6390.94410494.96040-0.340402.312801.60450HepG2AKAP8L
MNAT1ENSG00000020426.6534.34170841.78830-0.655703.758302.60890HepG2CCAR1
MNAT1ENSG00000020426.6587.94510778.63880-0.405302.523201.78010HepG2CIRBP
MNAT1ENSG00000020426.6344.44510492.53610-0.516004.903204.06480HepG2CKAP4
MNAT1ENSG00000020426.6159.06520455.63150-1.5182028.8633026.88640HepG2DDX19B
MNAT1ENSG00000020426.6130.86550439.98140-1.749409.584408.40200HepG2DDX21
MNAT1ENSG00000020426.6647.23530948.84480-0.551904.288503.52430HepG2DDX3X
MNAT1ENSG00000020426.6343.20220460.66810-0.424703.487102.76930HepG2DNAJC2
MNAT1ENSG00000020426.6390.47820533.93050-0.451402.380101.52220HepG2EEF2
MNAT1ENSG00000020426.6461.22820783.55530-0.764607.089106.17170HepG2EIF2S1
MNAT1ENSG00000020426.6502.64400865.94720-0.784707.121906.09700HepG2EIF4A3
MNAT1ENSG00000020426.6462.76250843.07050-0.865406.733105.69320HepG2EIF4B
MNAT1ENSG00000020426.6607.48890861.95500-0.504806.376905.52640HepG2ETF1
MNAT1ENSG00000020426.6380.79140556.53600-0.547504.035303.09450HepG2FUBP3
MNAT1ENSG00000020426.6564.29290873.62420-0.630605.410204.46420HepG2FXR1
MNAT1ENSG00000020426.6474.55440810.45680-0.772207.065906.02490HepG2G3BP1
MNAT1ENSG00000020426.6540.39810860.34860-0.670906.064404.73660HepG2G3BP2
MNAT1ENSG00000020426.6271.62290385.95080-0.506802.621901.75220HepG2GEMIN5
MNAT1ENSG00000020426.6326.36230469.18550-0.523703.340002.63840HepG2HNRNPA1
MNAT1ENSG00000020426.6406.40650521.89510-0.360801.896401.31080HepG2HNRNPC
MNAT1ENSG00000020426.6505.53510820.56240-0.698806.689005.63790HepG2HNRNPK
MNAT1ENSG00000020426.6256.25660494.05920-0.947108.160907.14260HepG2HNRNPLL
MNAT1ENSG00000020426.6381.57830518.44370-0.442203.739903.04570HepG2HNRNPU
MNAT1ENSG00000020426.6454.85280823.82660-0.856908.839807.70890HepG2IGF2BP2
MNAT1ENSG00000020426.6461.00810773.06530-0.745802.752001.77250HepG2IGF2BP3
MNAT1ENSG00000020426.6496.38800828.60070-0.739205.503904.04260HepG2KHSRP
MNAT1ENSG00000020426.6517.64140888.34640-0.779205.096803.95570HepG2LARP4
MNAT1ENSG00000020426.6462.20020873.92890-0.9190010.037808.81100HepG2MAGOH
MNAT1ENSG00000020426.6477.63430878.83320-0.879708.457907.40520HepG2MATR3
MNAT1ENSG00000020426.6268.88690523.17080-0.9603010.172508.71960HepG2MSI2
MNAT1ENSG00000020426.6370.68880899.54520-1.2790017.5063016.00270HepG2NCBP2
MNAT1ENSG00000020426.6628.45780767.13060-0.287702.235801.55010HepG2NOL12
MNAT1ENSG00000020426.6423.66510801.15240-0.919209.840408.49810HepG2PABPC4
MNAT1ENSG00000020426.6568.83740765.57280-0.428504.360903.62840HepG2PCBP1
MNAT1ENSG00000020426.6482.61710779.00610-0.690809.706008.80390HepG2PTBP1
MNAT1ENSG00000020426.6513.29280732.25710-0.512604.577903.83360HepG2PUF60
MNAT1ENSG00000020426.6537.52670777.28080-0.532106.299005.48010HepG2PUM1
MNAT1ENSG00000020426.6597.65520776.73940-0.378103.201302.47960HepG2PUM2
MNAT1ENSG00000020426.6398.63210501.80250-0.332102.349701.77070HepG2PUS1
MNAT1ENSG00000020426.6859.22330627.898000.452404.204603.17380HepG2RBM15
MNAT1ENSG00000020426.6419.46570720.42710-0.7803010.479609.61430HepG2RBM22
MNAT1ENSG00000020426.6455.43670866.95310-0.9287016.1847015.08380HepG2NELFE
MNAT1ENSG00000020426.6514.38660807.45970-0.650508.774207.76910HepG2RECQL
MNAT1ENSG00000020426.6256.79870421.75060-0.715805.481104.64780HepG2RPS19
MNAT1ENSG00000020426.6296.06040423.33530-0.515902.842701.89010HepG2SERBP1
MNAT1ENSG00000020426.6469.41660641.98520-0.451701.942801.37540HepG2SF3A3
MNAT1ENSG00000020426.6544.16540811.03310-0.575707.093006.21610HepG2SF3B4
MNAT1ENSG00000020426.6410.76870538.39490-0.390303.352102.65530HepG2SMN1
MNAT1ENSG00000020426.6377.77960544.01150-0.526102.825001.85830HepG2SMNDC1
MNAT1ENSG00000020426.6617.83100846.54820-0.454405.063004.47340HepG2SRSF1
MNAT1ENSG00000020426.6474.84370722.94640-0.606407.881906.89600HepG2SRSF5
MNAT1ENSG00000020426.6680.94110822.23270-0.272002.622502.01350HepG2SUCLG1
MNAT1ENSG00000020426.6370.43980481.50930-0.378301.952801.33020HepG2TARDBP
MNAT1ENSG00000020426.6397.44000508.27130-0.354902.641102.08700HepG2TRIM56
MNAT1ENSG00000020426.6770.21250552.955900.478003.289802.60970HepG2U2AF1
MNAT1ENSG00000020426.6364.94870549.67900-0.590905.602704.79910HepG2UTP3
MNAT1ENSG00000020426.6504.97600398.412000.341901.980801.35950HepG2XRN2
MNAT1ENSG00000020426.6463.50380626.16850-0.434004.521503.86650HepG2ZNF622
MNAT1ENSG00000020426.6841.54600663.101900.343703.256602.65040K562AGGF1
MNAT1ENSG00000020426.6579.75180781.01700-0.429902.671302.09210K562AQR
MNAT1ENSG00000020426.6870.30970723.979400.265502.115701.32420K562ATP5C1
MNAT1ENSG00000020426.6622.23000806.07690-0.373503.148901.96280K562CPEB4
MNAT1ENSG00000020426.6963.17810742.447400.375403.866202.80830K562DKC1
MNAT1ENSG00000020426.6458.46030596.15100-0.378902.940902.20300K562EIF2S2
MNAT1ENSG00000020426.6864.758001056.23550-0.288602.655601.73340K562EIF4G2
MNAT1ENSG00000020426.6382.44770492.34740-0.364401.993201.31580K562GPKOW
MNAT1ENSG00000020426.61003.40150732.235800.454402.426801.66010K562KIF1C
MNAT1ENSG00000020426.6395.71690595.36200-0.589302.287001.45510K562MATR3
MNAT1ENSG00000020426.61012.79040820.291800.304002.140001.35610K562MBNL1
MNAT1ENSG00000020426.6533.99010641.34160-0.264301.978801.33460K562NSUN2
MNAT1ENSG00000020426.61074.63220684.244400.651205.591304.85120K562PUS1
MNAT1ENSG00000020426.6918.24200666.725800.461704.949704.17780K562RBM15
MNAT1ENSG00000020426.6442.65660772.23250-0.802803.509001.97990K562SFPQ
MNAT1ENSG00000020426.6316.18330422.43630-0.418002.215901.38260K562TRIM56
MNAT1ENSG00000020426.6522.63260680.02760-0.379803.329002.54510K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MNAT1 is not available on ENCORE database.





4 RBPs can affect the splicing of MNAT1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEMNAT1ENSG00000020426.6chr14+613464316134655361285439612855656143494661435115-0.063000.001000.02094excludedK562SF3B4
SEMNAT1ENSG00000020426.6chr14+613463806134655361285360612855656143494661435396-0.097000.003040.03095excludedK562AQR
SEMNAT1ENSG00000020426.6chr14+612648046126487861263037612630876127504261275146-0.102000.000000.00007excludedK562AQR
SEMNAT1ENSG00000020426.6chr14+612854396128556561278704612788456134643161346553-0.056000.000570.01065excludedK562PUS1
SEMNAT1ENSG00000020426.6chr14+614349466143511561346431613465536143527661435398-0.156000.000960.04469excludedHepG2SF3B4
SEMNAT1ENSG00000020426.6chr14+614349466143511561346431613465536143527661435398-0.250000.000150.01038excludedK562HNRNPK
MXEMNAT1ENSG00000020426.6chr14+6134643161346553614349466143511561285439612855656143527661435398-0.054000.001890.060012includedHepG2SF3B4

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MNAT1 is not avaliable on ENCORE database.