FRS2

General Information

Gene Name       : FRS2
Gene ID             : ENSG00000166225.8
Essential Gene : No

Functions

Localization

Domains (AlphaFold: FRS2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878FRS2ENSG00000166225.85.244.324.78ENCSR000AEF
HepG2FRS2ENSG00000166225.87.589.658.62ENCSR985KAT
K562FRS2ENSG00000166225.83.834.063.94ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for FRS2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • FRS2 RNA is bound by 18 proteins.  







eCLIP assay for FRS2 is not avaliable on ENCORE database.





18 proteins are bound to FRS2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr126993156969931728+3'-UTR,intron-Distal,intron-Proximal3.824258.96569HepG2U2AF2
chr126995603569956089+3'-UTR,5'-UTR,intron-Proximal4.994285.01842HepG2PRPF8
chr126997222969972307+3'-UTR4.164493.51820HepG2PCBP2
chr126988530169885351+5'-UTR,intron-Distal,intron-Proximal3.171693.42293HepG2HNRNPC
chr126986415869864310+5'-UTR3.313784.71346HepG2NCBP2
chr126990925169909375+intron-Distal3.336483.23253K562SMNDC1
chr126988011369880206+intron-Distal,intron-Proximal3.724583.45805K562KHSRP
chr126991465769914705+intron-Distal5.091988.03988K562EXOSC5
chr126990925969909275+intron-Distal5.6851430.09728HepG2DKC1
chr126986910869869208+intron-Distal4.274893.60235HepG2HNRNPM
chr126990311369903186+intron-Distal3.809023.39864HepG2SUGP2
chr126988591769885936+intron-Distal4.252835.19823K562KHSRP
chr126993233569932417+intron-Distal4.214913.90026K562KHSRP
chr126986456069864683+intron-Distal4.877937.35452K562NONO
chr126991492469914965+intron-Distal4.752596.41216K562EXOSC5
chr126986436869864544+intron-Distal,intron-Proximal4.999898.01982HepG2EFTUD2
chr126992913669929226+intron-Distal3.021325.01170K562KHSRP
chr126993088169930949+intron-Distal3.120155.42536K562KHSRP
chr126991570569915771+intron-Distal4.873096.73640K562EXOSC5
chr126995724769957307+intron-Distal4.591594.51299HepG2SUGP2
chr126996325769963347+intron-Distal4.755696.64929HepG2QKI
chr126987054169870594+intron-Distal4.380633.19125K562GTF2F1
chr126991630269916363+intron-Distal4.167986.41051K562EXOSC5
chr126988221469882328+intron-Distal3.813544.06464HepG2CSTF2
chr126995048069950604+intron-Distal3.723513.25538K562KHSRP
chr126990385569903911+intron-Distal3.088733.35050HepG2SUGP2
chr126991472669914778+intron-Distal3.041793.37654K562EXOSC5
chr126990921869909259+intron-Distal5.5877524.61249HepG2DKC1
chr126988593669885987+intron-Distal3.296306.59733K562KHSRP
chr126993082569930881+intron-Distal3.374794.30679K562KHSRP
chr126987891169878959+intron-Distal4.289953.79905K562AGGF1
chr126993082469930956+intron-Distal3.682275.31346HepG2QKI
chr126987643669876528+intron-Distal4.439005.02888K562KHSRP
chr126992871469928861+intron-Distal5.5373113.09544K562KHSRP
chr126992899469929102+intron-Distal4.613524.05848HepG2QKI
chr126990927569909349+intron-Distal6.3660237.36740HepG2DKC1
chr126987417069874252+intron-Distal,intron-Proximal3.751803.42844K562KHSRP
chr126996295369963024+intron-Distal,intron-Proximal4.017055.75812K562PTBP1
chr126991719669917281+intron-Distal4.677545.44433K562EXOSC5
chr126991455869914615+intron-Distal4.651775.76685K562EXOSC5
chr126995805369958160+intron-Distal3.457986.96174HepG2SUGP2
chr126991436469914409+intron-Distal4.428794.80399K562EXOSC5
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for FRS2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for FRS2 is not available on ENCORE database.

  • 79 RBPs can affect the levels of FRS2.  








The Knockdown/knockout RNA-Seq assay for FRS2 is not available on ENCORE database.





79 RBPs can affect the gene expression of FRS2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
FRS2ENSG00000166225.4732.57040483.276300.600004.397903.23060HepG2ABCF1
FRS2ENSG00000166225.4583.01870394.121200.564806.245305.40690HepG2ACO1
FRS2ENSG00000166225.4593.07210395.967900.582703.925203.02340HepG2AKAP8L
FRS2ENSG00000166225.4880.26660504.389000.803309.596408.56670HepG2BOP1
FRS2ENSG00000166225.4531.26780394.029600.431003.834003.07540HepG2CKAP4
FRS2ENSG00000166225.4707.24040478.587900.563302.820902.04850HepG2CNOT7
FRS2ENSG00000166225.4712.93300463.066400.622405.408504.47720HepG2CPSF6
FRS2ENSG00000166225.4625.44270357.806800.805608.169807.06870HepG2DDX21
FRS2ENSG00000166225.4510.92070350.153400.545004.037602.92070HepG2DDX24
FRS2ENSG00000166225.4803.27490613.837700.387902.311101.73420HepG2DDX3X
FRS2ENSG00000166225.4261.55330451.34320-0.787103.665102.78860HepG2DDX55
FRS2ENSG00000166225.4689.39460377.065700.8704012.9841011.73790HepG2DKC1
FRS2ENSG00000166225.4247.62740393.02190-0.666406.469205.53070HepG2DNAJC2
FRS2ENSG00000166225.4538.86020385.102400.484602.775501.85410HepG2EEF2
FRS2ENSG00000166225.4851.66640560.266900.604104.644203.81840HepG2EIF4A3
FRS2ENSG00000166225.4942.24090545.362000.788806.014805.02930HepG2EIF4B
FRS2ENSG00000166225.4664.78250506.815900.391302.849602.00260HepG2EIF4G1
FRS2ENSG00000166225.4648.59670418.712400.631305.401503.92350HepG2ESF1
FRS2ENSG00000166225.4872.73690747.018700.224301.922301.40180HepG2ETF1
FRS2ENSG00000166225.4409.80580295.437200.472002.765801.98020HepG2FUBP3
FRS2ENSG00000166225.4700.97080524.298600.418902.478201.84650HepG2G3BP1
FRS2ENSG00000166225.4539.09130278.360000.953509.021707.45000HepG2GEMIN5
FRS2ENSG00000166225.4780.29490524.948900.571704.135503.36500HepG2GPKOW
FRS2ENSG00000166225.4726.24810400.325300.859203.630902.90460HepG2HNRNPA1
FRS2ENSG00000166225.4599.63930445.286800.429302.641201.96240HepG2HNRNPC
FRS2ENSG00000166225.4461.32630336.775300.453903.021602.02950HepG2HNRNPM
FRS2ENSG00000166225.4764.52710532.978600.520403.762602.98530HepG2IGF2BP2
FRS2ENSG00000166225.4872.82430500.014400.803602.169101.30730HepG2IGF2BP3
FRS2ENSG00000166225.4580.10240403.622500.523203.524902.14870HepG2LIN28B
FRS2ENSG00000166225.4758.95200565.265900.425002.659402.01630HepG2MAGOH
FRS2ENSG00000166225.4524.65040395.071700.409102.711701.91020HepG2MSI2
FRS2ENSG00000166225.4844.34500512.833800.7192011.2294010.14000HepG2PCBP1
FRS2ENSG00000166225.4722.34770520.141200.473702.333301.37670HepG2PCBP2
FRS2ENSG00000166225.4553.93830348.363200.669005.418404.32770HepG2PRPF8
FRS2ENSG00000166225.4702.87050521.819800.429603.981403.35160HepG2PTBP1
FRS2ENSG00000166225.4682.65160401.437200.7659011.5771010.46600HepG2PUS1
FRS2ENSG00000166225.41041.73640501.990201.053207.895606.74070HepG2RAVER1
FRS2ENSG00000166225.41083.61900624.378400.7953013.6559012.67960HepG2RBM22
FRS2ENSG00000166225.4664.00260512.913000.372402.465101.82460HepG2RBM25
FRS2ENSG00000166225.4610.46880463.269800.398002.479501.54570HepG2RBM27
FRS2ENSG00000166225.4423.08540304.191600.475902.820502.20050HepG2RPS19
FRS2ENSG00000166225.4545.67050427.302200.352702.080401.38000HepG2RPS2
FRS2ENSG00000166225.4446.16670344.621900.372501.978201.30270HepG2RRP9
FRS2ENSG00000166225.41518.03990591.196101.3604015.2630013.60470HepG2SF3A3
FRS2ENSG00000166225.4822.88700495.873000.730607.742006.61440HepG2SF3B1
FRS2ENSG00000166225.4719.72720543.295700.405603.516602.86130HepG2SF3B4
FRS2ENSG00000166225.4921.38320551.740000.739704.921703.86690HepG2SNRNP70
FRS2ENSG00000166225.41056.51520705.228200.583109.360308.58860HepG2SRFBP1
FRS2ENSG00000166225.41047.25240567.077400.8849017.7072016.72870HepG2SRSF1
FRS2ENSG00000166225.4564.41620461.342800.290801.966701.48660HepG2SRSF9
FRS2ENSG00000166225.41051.77580612.332600.7803015.9893014.96510HepG2SSB
FRS2ENSG00000166225.4406.43110546.09480-0.426103.342602.67180HepG2SUCLG1
FRS2ENSG00000166225.4427.53570329.620500.375102.270701.41400HepG2SUPT6H
FRS2ENSG00000166225.4698.73340449.359900.636804.698803.85320HepG2SUPV3L1
FRS2ENSG00000166225.4656.83440509.695500.365802.643302.09400HepG2TAF15
FRS2ENSG00000166225.4872.17310488.215000.837009.870308.62540HepG2TARDBP
FRS2ENSG00000166225.4533.43750429.822700.311501.893901.46290HepG2TIAL1
FRS2ENSG00000166225.4267.74280433.66080-0.695707.170906.33620HepG2TRIM56
FRS2ENSG00000166225.4696.90530475.058800.552804.485803.34190HepG2TUFM
FRS2ENSG00000166225.4836.26810506.192200.7242011.2394010.16390HepG2UTP3
FRS2ENSG00000166225.4759.64030552.015800.460502.325201.35480HepG2XRCC6
FRS2ENSG00000166225.4731.22750382.900000.9333017.1848015.75760HepG2ZC3H8
FRS2ENSG00000166225.4698.65050576.630600.276802.335001.82030HepG2ZNF622
FRS2ENSG00000166225.4254.39300365.47880-0.522703.327002.71590K562AGGF1
FRS2ENSG00000166225.4261.52950380.29740-0.540203.178102.47730K562AKAP8L
FRS2ENSG00000166225.42480.63970409.074002.60020102.9054099.91700K562AQR
FRS2ENSG00000166225.4869.71680655.761500.407302.920701.92050K562CELF1
FRS2ENSG00000166225.4573.65650451.510900.345302.565501.93500K562DDX47
FRS2ENSG00000166225.4204.94260124.111100.723502.329001.41390K562EIF3A
FRS2ENSG00000166225.4418.13820208.024001.007109.706708.15930K562EIF4A3
FRS2ENSG00000166225.4670.26690533.544500.329002.158101.32290K562EIF4G2
FRS2ENSG00000166225.4287.89030405.53940-0.494302.896402.02790K562FIP1L1
FRS2ENSG00000166225.4422.65290216.335100.9661010.297609.21520K562FXR1
FRS2ENSG00000166225.4418.23980231.895800.850805.629204.54010K562G3BP2
FRS2ENSG00000166225.4312.30200214.735600.540302.819302.21690K562HNRNPC
FRS2ENSG00000166225.4332.32910248.545700.419002.182201.47080K562POLR2G
FRS2ENSG00000166225.4296.82260460.38760-0.633204.600603.50470K562PPIG
FRS2ENSG00000166225.4486.14440215.281601.1751011.7676010.20970K562PRPF8
FRS2ENSG00000166225.41125.71010582.172900.951209.916508.35140K562PUF60
FRS2ENSG00000166225.4228.67270377.14980-0.721903.296902.71200K562PUS1
FRS2ENSG00000166225.4390.05690297.892600.388802.030901.31580K562RBM22
FRS2ENSG00000166225.4424.44810325.566600.382502.248801.50810K562SF3A3
FRS2ENSG00000166225.4456.75360333.732700.452602.181701.32910K562SF3B1
FRS2ENSG00000166225.4481.72710333.545400.530204.531403.36780K562SRPK2
FRS2ENSG00000166225.4433.50020304.558100.509203.336002.56430K562SRSF1
FRS2ENSG00000166225.4306.55190208.490700.556002.681101.68050K562SUPV3L1
FRS2ENSG00000166225.4348.86700224.832000.633703.508202.24350K562U2AF1
FRS2ENSG00000166225.4368.14030232.186300.664905.030103.94990K562U2AF2
FRS2ENSG00000166225.4423.40600311.308900.443603.262402.35060K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for FRS2 is not available on ENCORE database.





1 RBPs can affect the splicing of FRS2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEFRS2ENSG00000166225.4chr12+698853176988543169864199698643106992464469924740-0.089000.002380.02536excludedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for FRS2 is not avaliable on ENCORE database.