CISD2

General Information

Gene Name       : CISD2
Gene ID             : ENSG00000145354.11
Essential Gene : No

Functions

Localization

Domains (AlphaFold: CISD2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878CISD2ENSG00000145354.1122.8721.3722.12ENCSR000AEF
HepG2CISD2ENSG00000145354.1122.0938.8830.48ENCSR985KAT
K562CISD2ENSG00000145354.1134.0435.9835.01ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
CISD2Ribo-STAMP-293TshRNACISD2-BGRSLV03-13,CISD2-BGRSLV03-14NT-BGRSLV03-1,NT-BGRSLV03-2,SubmittedENCORE2
CISD2Ribo-STAMP-293TshRNABGRSDLV02-81,BGRSDLV02-82BGRSDLV02-1,BGRSDLV02-2SubmittedENCORE2
CISD2Ribo-STAMP-293TshRNACISD2-BGRSDLV02-83dox,CISD2-BGRSDLV02-84doxCISD2-BGRSDLV02-81,CISD2-BGRSDLV02-82,SubmittedENCORE2


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for CISD2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • CISD2 RNA is bound by 10 proteins.  







eCLIP assay for CISD2 is not avaliable on ENCORE database.





10 proteins are bound to CISD2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr4103808944103809013+3'-UTR4.584844.80693HepG2FUBP3
chr4103809220103809285+3'-UTR4.6770611.00366K562TARDBP
chr4103809473103809541+3'-UTR3.315043.99870K562IGF2BP1
chr4103809225103809277+3'-UTR4.759964.77410HepG2SUB1
chr4103809199103809287+3'-UTR3.144704.68114K562DDX55
chr4103806394103806478+3'-UTR,CDS4.159494.24698K562IGF2BP1
chr4103790187103790345+5'-UTR,CDS,intron-Proximal3.5042811.54817K562FTO
chr4103790154103790220+5'-UTR3.759196.96130K562IGF2BP2
chr4103790152103790282+5'-UTR,CDS5.0779944.38010HepG2DDX3X
chr4103790220103790264+5'-UTR,CDS3.397725.23690K562IGF2BP2
chr4103790155103790283+5'-UTR,CDS4.8303440.26579K562DDX3X
chr4103790184103790336+5'-UTR,CDS3.977804.85687K562DROSHA
chr4103790282103790326+CDS3.531497.30480HepG2DDX3X
chr4103790283103790348+CDS,intron-Proximal4.1285923.42383K562DDX3X
chr4103796001103796122+intron-Distal3.235783.18966K562MATR3
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for CISD2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for CISD2 is not available on ENCORE database.

  • 88 RBPs can affect the levels of CISD2.  








The Knockdown/knockout RNA-Seq assay for CISD2 is not available on ENCORE database.





88 RBPs can affect the gene expression of CISD2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
CISD2ENSG00000145354.51449.490301092.639400.407602.602902.08610HepG2AKAP1
CISD2ENSG00000145354.5884.78040602.538900.554205.923604.85170HepG2CALR
CISD2ENSG00000145354.5392.53960539.34850-0.458404.323503.52740HepG2CKAP4
CISD2ENSG00000145354.5683.33920891.07990-0.383004.547403.63310HepG2DAZAP1
CISD2ENSG00000145354.5607.33810471.551700.365002.272001.45370HepG2DDX24
CISD2ENSG00000145354.5374.47620589.07530-0.653604.178703.24970HepG2DDX55
CISD2ENSG00000145354.5584.96410899.06840-0.620104.623103.84240HepG2DDX6
CISD2ENSG00000145354.5357.47640475.77700-0.412403.437502.72440HepG2DNAJC2
CISD2ENSG00000145354.5539.78600864.35760-0.679206.004805.14930HepG2EIF2S1
CISD2ENSG00000145354.5637.95890955.24640-0.582404.470603.66050HepG2EIF4A3
CISD2ENSG00000145354.5668.51880527.149500.342702.244901.49310HepG2EWSR1
CISD2ENSG00000145354.5580.79560963.71380-0.730607.287406.20120HepG2FXR1
CISD2ENSG00000145354.5642.98030894.03310-0.475603.211302.49780HepG2G3BP1
CISD2ENSG00000145354.5722.28990949.06900-0.393902.581901.72380HepG2G3BP2
CISD2ENSG00000145354.5379.40320539.03210-0.506603.276402.52780HepG2HNRNPC
CISD2ENSG00000145354.5384.34960566.79200-0.560405.261204.31190HepG2HNRNPF
CISD2ENSG00000145354.5622.02840905.17930-0.541204.537003.66210HepG2HNRNPK
CISD2ENSG00000145354.5622.96710811.70930-0.381804.287803.46220HepG2HNRNPL
CISD2ENSG00000145354.5610.20510444.185100.458002.474501.31640HepG2HSPD1
CISD2ENSG00000145354.5685.86480908.78190-0.406002.548101.89780HepG2IGF2BP2
CISD2ENSG00000145354.5605.12780914.04790-0.595003.907202.69830HepG2KHSRP
CISD2ENSG00000145354.5662.06740964.04990-0.542104.166403.36400HepG2MAGOH
CISD2ENSG00000145354.5397.35740992.30820-1.3204019.1639017.59290HepG2NCBP2
CISD2ENSG00000145354.5726.29480883.59230-0.282802.124801.45460HepG2NOL12
CISD2ENSG00000145354.5661.70700883.76970-0.417502.677701.96690HepG2PABPC4
CISD2ENSG00000145354.5302.38990530.01530-0.809609.878908.44490HepG2PARN
CISD2ENSG00000145354.5601.55700847.40880-0.494405.794604.96740HepG2PCBP1
CISD2ENSG00000145354.5529.20150862.26000-0.7043010.333709.40740HepG2PTBP1
CISD2ENSG00000145354.5764.68680895.36880-0.227602.044801.51950HepG2PUM1
CISD2ENSG00000145354.5678.06840933.87050-0.461804.716103.93220HepG2QKI
CISD2ENSG00000145354.5860.51430559.964100.619803.064502.32430HepG2RAVER1
CISD2ENSG00000145354.5998.01900782.072900.351703.118802.57730HepG2RBM22
CISD2ENSG00000145354.5688.01400959.62100-0.480005.781805.04520HepG2NELFE
CISD2ENSG00000145354.5522.48420893.74130-0.7745012.8034011.62340HepG2RECQL
CISD2ENSG00000145354.5424.88400610.47900-0.522903.567802.80870HepG2RPLP0
CISD2ENSG00000145354.5209.39350376.52870-0.846506.124005.25050HepG2RPS19
CISD2ENSG00000145354.5611.60930476.854900.359003.059402.38820HepG2SAFB2
CISD2ENSG00000145354.5603.96670897.74220-0.571807.649206.74490HepG2SF3B4
CISD2ENSG00000145354.5601.87990808.74090-0.426204.919904.02580HepG2SLBP
CISD2ENSG00000145354.5446.25170556.08850-0.317502.520201.90190HepG2SMN1
CISD2ENSG00000145354.5948.22410655.051700.533502.790602.00680HepG2SNRNP70
CISD2ENSG00000145354.5446.82390556.83250-0.317501.957301.36110HepG2SRSF7
CISD2ENSG00000145354.5551.22200762.32640-0.467804.119203.47060HepG2SRSF9
CISD2ENSG00000145354.5774.61460947.11780-0.290102.870402.23950HepG2SUCLG1
CISD2ENSG00000145354.5297.95750579.76850-0.960409.890008.64420HepG2TARDBP
CISD2ENSG00000145354.5569.58830773.91500-0.442303.764502.79640HepG2TIA1
CISD2ENSG00000145354.5231.86610520.28840-1.1660015.9172014.89520HepG2TIAL1
CISD2ENSG00000145354.5351.83430524.95950-0.577305.938705.16840HepG2TRIM56
CISD2ENSG00000145354.5655.79640824.02070-0.329402.272201.48560HepG2TUFM
CISD2ENSG00000145354.5505.34370872.20860-0.787406.913705.56180HepG2UBE2L3
CISD2ENSG00000145354.5372.23960285.831900.381002.327801.70450HepG2ZC3H8
CISD2ENSG00000145354.5509.47820668.71190-0.392404.009003.38340HepG2ZNF622
CISD2ENSG00000145354.51254.147001637.24000-0.384603.135801.82140K562ABCF1
CISD2ENSG00000145354.51448.545701181.150000.294303.290902.68200K562AGGF1
CISD2ENSG00000145354.51002.586001545.93110-0.624808.098305.89000K562APOBEC3C
CISD2ENSG00000145354.51166.695301741.45030-0.577905.481604.70480K562AQR
CISD2ENSG00000145354.5662.95020877.13050-0.403904.378303.15280K562BCLAF1
CISD2ENSG00000145354.5825.031001140.33680-0.466903.547001.90180K562BUD13
CISD2ENSG00000145354.5594.76960955.69180-0.684206.046203.81610K562CKAP4
CISD2ENSG00000145354.5931.941801606.92210-0.786005.577904.00930K562CNOT7
CISD2ENSG00000145354.51099.060501416.40330-0.366004.266102.87040K562CPEB4
CISD2ENSG00000145354.5718.020301080.07480-0.589006.967105.71420K562CPSF6
CISD2ENSG00000145354.5562.97130786.15250-0.481704.213102.88660K562DDX3X
CISD2ENSG00000145354.51849.498101465.458600.335704.762103.94080K562DDX47
CISD2ENSG00000145354.51636.081401322.570900.306803.344902.37070K562DKC1
CISD2ENSG00000145354.5920.883801207.12420-0.390502.552301.85630K562EIF2S2
CISD2ENSG00000145354.5611.89770821.35910-0.424703.228302.34430K562EIF4A3
CISD2ENSG00000145354.5422.76420613.64780-0.537603.075301.73670K562EXOSC5
CISD2ENSG00000145354.5777.463001098.90430-0.499204.359003.28460K562FMR1
CISD2ENSG00000145354.5663.62880931.40050-0.489003.317202.30940K562FTO
CISD2ENSG00000145354.51107.08690769.162700.525303.476502.66550K562G3BP2
CISD2ENSG00000145354.5745.122401031.22470-0.468803.863802.93300K562GPKOW
CISD2ENSG00000145354.5551.14730902.04020-0.710808.387807.39970K562HNRNPC
CISD2ENSG00000145354.5378.80210805.64820-1.0887016.2825013.50830K562HNRNPF
CISD2ENSG00000145354.51292.95280967.869500.417702.871901.92110K562HNRNPM
CISD2ENSG00000145354.51668.161801304.335500.354802.926302.07530K562KIF1C
CISD2ENSG00000145354.5492.09660880.48730-0.839406.936505.38790K562KRR1
CISD2ENSG00000145354.5672.931901006.58230-0.580906.165404.83250K562METAP2
CISD2ENSG00000145354.5605.04870999.84270-0.7246012.9978011.40520K562MTPAP
CISD2ENSG00000145354.5628.74820820.14390-0.383403.014801.73370K562NCBP2
CISD2ENSG00000145354.5804.435201110.85960-0.465607.578906.42840K562NSUN2
CISD2ENSG00000145354.51064.433201543.77900-0.536402.782701.54420K562PABPC1
CISD2ENSG00000145354.5240.32160417.37460-0.796403.994001.47840K562PARN
CISD2ENSG00000145354.5952.13630670.922300.504904.175703.25470K562PRPF8
CISD2ENSG00000145354.5538.97470808.80830-0.585605.297403.99220K562PSIP1
CISD2ENSG00000145354.52322.360001911.558700.280702.183701.46040K562PUF60
CISD2ENSG00000145354.51772.108401218.913000.539803.188202.61220K562PUS1
CISD2ENSG00000145354.51481.503801187.606200.318903.206202.57510K562RBM15
CISD2ENSG00000145354.51038.95640686.061100.598604.209702.56550K562RRP9
CISD2ENSG00000145354.5860.335601096.21740-0.349603.520402.60720K562SF3A3
CISD2ENSG00000145354.5498.92460699.68220-0.487903.654202.42850K562SRFBP1
CISD2ENSG00000145354.5849.635101071.63040-0.334902.013101.39890K562SRSF1
CISD2ENSG00000145354.5347.45140477.00240-0.457202.752101.70500K562SRSF4
CISD2ENSG00000145354.5436.46680777.91800-0.833708.396206.69360K562TIAL1
CISD2ENSG00000145354.5442.93910826.62440-0.9001011.442209.23190K562TRIM56
CISD2ENSG00000145354.5847.694201177.87230-0.474606.673605.61130K562UPF1
CISD2ENSG00000145354.5522.34170700.06100-0.422502.586201.43290K562XRN2
CISD2ENSG00000145354.51184.661501961.99950-0.727805.609604.30910K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for CISD2 is not available on ENCORE database.





1 RBPs can affect the splicing of CISD2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECISD2ENSG00000145354.5chr4+1038039271038040301037902101037903441038063721038065870.072000.000580.01208includedK562HNRNPC

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for CISD2 is not avaliable on ENCORE database.