GEMIN8

General Information

Gene Name       : GEMIN8
Gene ID             : ENSG00000046647.13
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: GEMIN8)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878GEMIN8ENSG00000046647.1316.0217.6116.81ENCSR000AEF
HepG2GEMIN8ENSG00000046647.1312.4811.5312.00ENCSR985KAT
K562GEMIN8ENSG00000046647.1314.6911.9313.31ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for GEMIN8 is not avaliable on ENCORE database.



Proteins bound to RNA
  • GEMIN8 RNA is bound by 6 proteins.  







eCLIP assay for GEMIN8 is not avaliable on ENCORE database.





6 proteins are bound to GEMIN8 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chrX1402692714027029-3'-UTR,intron-Distal5.5905310.92669K562PUM2
chrX1403820014038305-CDS,intron-Distal4.587264.72838K562UCHL5
chrX1403820614038274-CDS,intron-Distal4.241303.89826HepG2BCLAF1
chrX1403819614038394-CDS,intron-Distal,intron-Proximal3.314704.06531HepG2GRWD1
chrX1404778614047868-intron-Distal,intron-Proximal3.693836.38533K562RBM22
chrX1404781614047876-intron-Distal,intron-Proximal5.697158.75564HepG2RBM22
chrX1404392714044088-intron-Distal,intron-Proximal4.688105.58765HepG2QKI
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for GEMIN8 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for GEMIN8 is not available on ENCORE database.

  • 22 RBPs can affect the levels of GEMIN8.  








The Knockdown/knockout RNA-Seq assay for GEMIN8 is not available on ENCORE database.





22 RBPs can affect the gene expression of GEMIN8 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
GEMIN8ENSG00000046647.961.66030100.03870-0.698101.920201.34280HepG2DDX21
GEMIN8ENSG00000046647.9103.60120179.61400-0.793903.153102.47170HepG2EIF4A3
GEMIN8ENSG00000046647.9151.67090238.03220-0.650203.844303.15560HepG2ETF1
GEMIN8ENSG00000046647.966.73940128.03860-0.940002.873302.08860HepG2FIP1L1
GEMIN8ENSG00000046647.9112.55860182.28910-0.695602.446701.85080HepG2MATR3
GEMIN8ENSG00000046647.961.83600103.61220-0.744702.063701.35990HepG2MSI2
GEMIN8ENSG00000046647.9101.13780186.58480-0.883503.811303.07370HepG2NCBP2
GEMIN8ENSG00000046647.9116.19380178.50640-0.619402.371901.85890HepG2PTBP1
GEMIN8ENSG00000046647.9118.89400193.34540-0.701503.223802.55680HepG2QKI
GEMIN8ENSG00000046647.9117.05300175.46630-0.584002.275401.65880HepG2RBM25
GEMIN8ENSG00000046647.935.2661086.81800-1.299704.218703.47470HepG2RPS19
GEMIN8ENSG00000046647.9104.33950185.86380-0.833004.173803.47120HepG2SF3B4
GEMIN8ENSG00000046647.9115.87950193.99520-0.743403.576303.05550HepG2SRSF1
GEMIN8ENSG00000046647.9118.94020195.07330-0.713803.845403.26300HepG2SSB
GEMIN8ENSG00000046647.9111.34420174.35280-0.647002.803202.23970HepG2TAF15
GEMIN8ENSG00000046647.988.17570171.40370-0.958904.329803.20630HepG2TUFM
GEMIN8ENSG00000046647.9155.34070233.89670-0.590402.826302.16570K562AKAP8L
GEMIN8ENSG00000046647.9210.32320301.38130-0.519002.065901.54430K562AQR
GEMIN8ENSG00000046647.972.57810135.59380-0.901703.349602.70110K562HNRNPC
GEMIN8ENSG00000046647.9149.10890231.99710-0.637702.524502.00050K562PUS1
GEMIN8ENSG00000046647.9159.60800226.01660-0.501902.250901.70690K562RBM15
GEMIN8ENSG00000046647.9305.68250211.311600.532602.771101.67760K562NELFE
GEMIN8ENSG00000046647.9126.07480205.31410-0.703603.361602.58740K562SRSF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for GEMIN8 is not available on ENCORE database.





2 RBPs can affect the splicing of GEMIN8 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEGEMIN8ENSG00000046647.9chrX-1404417014044340140395821403963014047895140480110.561000.000050.00242includedHepG2HNRNPK
SEGEMIN8ENSG00000046647.9chrX-1404417014044340140395821403963014047895140480110.394000.001480.07632includedHepG2AKAP1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for GEMIN8 is not avaliable on ENCORE database.