USP10

General Information

Gene Name : USP10
Gene ID : ENSG00000103194.15
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: USP10)

Not Available

Antibody Validation

View validation images for all USP10 antibodies

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	USP10	ENSG00000103194.15	125.06	90.37	107.72	ENCSR000AEF
HepG2	USP10	ENSG00000103194.15	103.52	92.50	98.01	ENCSR985KAT
K562	USP10	ENSG00000103194.15	116.44	132.70	124.57	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Product_ID	Lot_ID	K562 Primary Validation	K562 Secondary Validation
USP10	8501	3		BGKcLV37-55, Submitted, ENCORE2
USP10	A300-900A	2		BGKcLV37-55, Submitted, ENCORE2
USP10	A300-901A	2		BGKcLV37-55, Submitted, ENCORE2
USP10	8501S	3	Submitted, ENCORE2

KD RNA-Seq

GeneName	Cell_Line	Method	Sample_reps	Control_reps	KD%	Status	Project
USP10	K562	CRISPR	USP10-BGKcLV37-55,USP10-BGKcLV37-56	NT-BGKcLV37-1,NT-BGKcLV37-2	84.1,84.0	Submitting	ENCORE2
USP10	HepG2	CRISPR	BGHcLV36-53,BGHcLV36-54	BGHcLV36-1,BGHcLV36-2	NO CLEAR BAND ON THE POSITION,	NotSatisfied	ENCORE2
USP10	HepG2	CRISPR	BGHcLV47-85,BGHcLV47-86	BGHcLV47-1,BGHcLV47-2	90.7,83.5	Sequenced	ENCORE2
USP10	HepG2	CRISPR	BGHcLV47-87,BGHcLV47-88	BGHcLV47-1,BGHcLV47-2		NotSatisfied	ENCORE2

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
USP10	Product_ID: 8501S Lot_ID: 3 Source: Cell Signaling Technology Target Name: USP10-human
USP10	Product_ID: 8501 Lot_ID: 3 Source: Cell Signaling Technology Target Name: USP10-human
USP10	Product_ID: A300-900A Lot_ID: 2 Source: Bethyl Labs Target Name: USP10-human
USP10	Product_ID: A300-901A Lot_ID: Source: Bethyl Labs Target Name: USP10-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for USP10 is not avaliable on ENCORE database.

Proteins bound to RNA

USP10 RNA is bound by 52 proteins.

CanvasJS.com

eCLIP assay for USP10 is not avaliable on ENCORE database.

52 proteins are bound to USP10 RNA:

Show entries

Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr16	84813263	84813331	+	3'-UTR	4.98266	63.17108	K562	PABPC4
chr16	84789462	84789547	+	intron-Distal	6.05134	52.14400	HepG2	QKI
chr16	84789454	84789551	+	intron-Distal	6.22853	51.68791	K562	QKI
chr16	84746002	84746095	+	intron-Distal	5.53551	20.53635	HepG2	HNRNPM
chr16	84809441	84809538	+	intron-Distal	6.47302	19.26307	K562	PTBP1
chr16	84745996	84746067	+	intron-Distal	5.16643	18.89264	K562	HNRNPM
chr16	84797696	84797713	+	3'-UTR,CDS	5.28249	18.71148	K562	YBX3
chr16	84803448	84803537	+	intron-Distal	5.23819	18.42282	K562	EXOSC5
chr16	84753815	84753911	+	intron-Distal	5.23056	16.86383	HepG2	HNRNPM
chr16	84797713	84797753	+	3'-UTR,CDS	4.30503	15.72912	K562	YBX3
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 217 entries

eCLIP assay for USP10 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for USP10 is not available on ENCORE database.
83 RBPs can affect the levels of USP10.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for USP10 is not available on ENCORE database.

83 RBPs can affect the gene expression of USP10 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
USP10	ENSG00000103194.11	1785.74650	3339.91310	-0.90330	26.97060	24.78580	HepG2	NOL12
USP10	ENSG00000103194.11	2064.07000	3145.38380	-0.60770	18.68270	17.18040	HepG2	UPF1
USP10	ENSG00000103194.11	1877.93630	3463.42360	-0.88310	17.23170	15.63400	HepG2	SF3B1
USP10	ENSG00000103194.11	4349.09670	3036.73640	0.51810	15.22370	13.98820	HepG2	UTP3
USP10	ENSG00000103194.11	1608.98610	2537.76350	-0.65740	12.76270	11.82430	HepG2	TIAL1
USP10	ENSG00000103194.11	1999.10410	3188.15240	-0.67340	12.08800	10.96050	HepG2	PUF60
USP10	ENSG00000103194.11	4082.30340	2851.88100	0.51740	12.04120	10.87060	K562	FXR1
USP10	ENSG00000103194.11	1607.81790	2629.14620	-0.70950	11.55650	10.22360	HepG2	HNRNPC
USP10	ENSG00000103194.11	2100.26400	3499.11740	-0.73640	11.05200	9.89730	HepG2	HNRNPLL
USP10	ENSG00000103194.11	1867.64390	2611.76290	-0.48380	10.93660	9.79810	HepG2	HNRNPU
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 98 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for USP10 is not available on ENCORE database.

31 RBPs can affect the splicing of USP10 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	FDR	is_included	Cell Line	Affected by RBP
SE	USP10	ENSG00000103194.11	chr16	+	84806146	84806291	84801798	84801964	84808765	84808831	-0.07900	0.00003	excluded	HepG2	U2AF1
SE	USP10	ENSG00000103194.11	chr16	+	84773914	84773975	84766743	84767109	84778238	84778472	-0.14100	0.00000	excluded	K562	AKAP8L
SE	USP10	ENSG00000103194.11	chr16	+	84808765	84808831	84806146	84806291	84812500	84813187	-0.18100	0.00000	excluded	K562	AKAP8L
SE	USP10	ENSG00000103194.11	chr16	+	84766658	84766711	84733609	84733717	84767040	84767109	0.10000	0.00001	included	K562	XRCC6
SE	USP10	ENSG00000103194.11	chr16	+	84766658	84766711	84733609	84733717	84767040	84767109	0.07300	0.00000	included	K562	AQR
SE	USP10	ENSG00000103194.11	chr16	+	84808765	84808831	84806146	84806291	84812500	84813528	0.13700	0.00001	included	K562	FXR1
SE	USP10	ENSG00000103194.11	chr16	+	84773914	84773975	84766743	84767109	84778238	84778386	-0.33300	0.00000	excluded	K562	PUS1
SE	USP10	ENSG00000103194.11	chr16	+	84808765	84808831	84806146	84806291	84812500	84813187	-0.23300	0.00000	excluded	K562	PUS1
SE	USP10	ENSG00000103194.11	chr16	+	84766658	84766711	84733609	84733717	84767040	84767109	0.09400	0.00832	included	K562	SSB
SE	USP10	ENSG00000103194.11	chr16	+	84773914	84773975	84766743	84767109	84792321	84792413	-0.19000	0.00036	excluded	HepG2	SF3A3

Showing 1 to 10 of 102 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

USP10

General Information

Functions

Localization

Domains (AlphaFold: USP10)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for USP10 is not avaliable on ENCORE database.

52 proteins are bound to USP10 RNA:

eCLIP assay for USP10 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for USP10 is not available on ENCORE database.

83 RBPs can affect the gene expression of USP10 :

The Knockdown/knockout RNA-Seq assay for USP10 is not available on ENCORE database.

31 RBPs can affect the splicing of USP10 :

The Knockdown/knockout RNA-Seq assay for USP10 is not avaliable on ENCORE database.