SIRT2

General Information

Gene Name : SIRT2
Gene ID : ENSG00000068903.19
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: SIRT2)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	SIRT2	ENSG00000068903.19	10.26	17.27	13.77	ENCSR000AEF
HepG2	SIRT2	ENSG00000068903.19	15.67	11.60	13.63	ENCSR985KAT
K562	SIRT2	ENSG00000068903.19	23.55	23.67	23.61	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for SIRT2 is not avaliable on ENCORE database.

Proteins bound to RNA

SIRT2 RNA is bound by 11 proteins.

CanvasJS.com

eCLIP assay for SIRT2 is not avaliable on ENCORE database.

11 proteins are bound to SIRT2 RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr19	39369372	39369599	-	3'-UTR,intron-Distal	5.52013	26.20392	K562	UPF1
chr19	39369233	39369303	-	3'-UTR,intron-Distal	5.45637	10.00893	K562	UPF1
chr19	39369431	39369519	-	3'-UTR,intron-Distal	3.47463	8.70859	K562	QKI
chr19	39369400	39369488	-	3'-UTR,intron-Distal	3.98605	7.88838	K562	IGF2BP2
chr19	39384287	39384383	-	intron-Distal,intron-Proximal	4.19556	6.40042	K562	EFTUD2
chr19	39389913	39390064	-	intron-Distal	3.10932	6.26922	K562	CSTF2T
chr19	39372011	39372079	-	3'-UTR,CDS,intron-Distal,intron-Proximal	4.93262	6.04760	K562	AQR
chr19	39371274	39371327	-	CDS,intron-Distal,intron-Proximal	4.93262	6.04760	K562	AQR
chr19	39384053	39384126	-	5'-UTR,CDS,intron-Distal,intron-Proximal	4.26718	4.38106	HepG2	PPIG
chr19	39389870	39390030	-	intron-Distal	4.22926	4.33692	K562	NONO
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 14 entries

eCLIP assay for SIRT2 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for SIRT2 is not available on ENCORE database.
113 RBPs can affect the levels of SIRT2.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for SIRT2 is not available on ENCORE database.

113 RBPs can affect the gene expression of SIRT2 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
SIRT2	ENSG00000068903.15	1134.61330	320.94240	1.82170	53.67330	51.99960	HepG2	TIAL1
SIRT2	ENSG00000068903.15	1122.27740	642.38520	0.80480	19.83500	18.70090	HepG2	ZNF622
SIRT2	ENSG00000068903.15	733.07470	302.68500	1.27600	18.95760	17.59900	HepG2	BOP1
SIRT2	ENSG00000068903.15	935.69820	471.79890	0.98780	13.82500	12.51460	HepG2	RPLP0
SIRT2	ENSG00000068903.15	764.64410	427.63630	0.83830	13.12420	11.87270	HepG2	DKC1
SIRT2	ENSG00000068903.15	405.06990	705.17510	-0.79980	12.50660	11.48220	HepG2	SRSF9
SIRT2	ENSG00000068903.15	1219.59230	670.69050	0.86260	10.81360	9.37760	HepG2	CIRBP
SIRT2	ENSG00000068903.15	605.68230	300.59130	1.01070	10.31800	9.19290	HepG2	HNRNPLL
SIRT2	ENSG00000068903.15	306.89020	532.94040	-0.79630	9.65250	8.80810	HepG2	SSB
SIRT2	ENSG00000068903.15	925.18080	493.99710	0.90510	10.35060	8.44070	K562	TIAL1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 130 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for SIRT2 is not available on ENCORE database.

16 RBPs can affect the splicing of SIRT2 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	SIRT2	ENSG00000068903.15	chr19	-	39389018	39389065	39384458	39384507	39390145	39390463	0.23800	0.00000	0.00005	included	K562	FXR1
SE	SIRT2	ENSG00000068903.15	chr19	-	39389018	39389065	39384458	39384507	39390145	39390463	0.14000	0.00006	0.01934	included	K562	APOBEC3C
SE	SIRT2	ENSG00000068903.15	chr19	-	39389018	39389065	39384458	39384611	39390145	39390463	0.44500	0.00008	0.06623	included	HepG2	PPIG
SE	SIRT2	ENSG00000068903.15	chr19	-	39389018	39389065	39384458	39384611	39390145	39390463	0.43900	0.00011	0.03690	included	K562	PUM1
SE	SIRT2	ENSG00000068903.15	chr19	-	39389018	39389065	39384458	39384507	39390145	39390463	-0.19500	0.00012	0.02716	excluded	K562	NSUN2
SE	SIRT2	ENSG00000068903.15	chr19	-	39389018	39389065	39384458	39384507	39390145	39390463	0.11500	0.00012	0.07516	included	K562	PUM2
SE	SIRT2	ENSG00000068903.15	chr19	-	39389018	39389065	39384458	39384507	39390145	39390463	0.25700	0.00020	0.02859	included	HepG2	LARP4
SE	SIRT2	ENSG00000068903.15	chr19	-	39381204	39381302	39380742	39380784	39384053	39384167	0.11800	0.00025	0.00596	included	K562	HNRNPC
A3SS	SIRT2	ENSG00000068903.15	chr19	-	39370271	39370443	39370271	39370342	39371324	39371489	0.15500	0.00027	0.02577	longer	HepG2	SF3A3
RI	SIRT2	ENSG00000068903.15	chr19	-	39371324	39371489	39371324	39371376	39371460	39371489	0.06900	0.00034	0.00253	included	K562	AQR

Showing 1 to 10 of 19 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

SIRT2

General Information

Functions

Localization

Domains (AlphaFold: SIRT2)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for SIRT2 is not avaliable on ENCORE database.

11 proteins are bound to SIRT2 RNA:

eCLIP assay for SIRT2 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for SIRT2 is not available on ENCORE database.

113 RBPs can affect the gene expression of SIRT2 :

The Knockdown/knockout RNA-Seq assay for SIRT2 is not available on ENCORE database.

16 RBPs can affect the splicing of SIRT2 :

The Knockdown/knockout RNA-Seq assay for SIRT2 is not avaliable on ENCORE database.