ORC2

General Information

Gene Name : ORC2
Gene ID : ENSG00000115942.8
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: ORC2)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	ORC2	ENSG00000115942.8	16.42	14.23	15.33	ENCSR000AEF
HepG2	ORC2	ENSG00000115942.8	30.57	56.15	43.36	ENCSR985KAT
K562	ORC2	ENSG00000115942.8	17.47	17.34	17.41	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for ORC2 is not avaliable on ENCORE database.

Proteins bound to RNA

ORC2 RNA is bound by 30 proteins.

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eCLIP assay for ORC2 is not avaliable on ENCORE database.

30 proteins are bound to ORC2 RNA:

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Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr2	201778064	201778119	-	CDS,intron-Distal	4.53813	48.09493	HepG2	U2AF2
chr2	201814309	201814362	-	CDS,intron-Distal	4.48306	36.52793	HepG2	BCLAF1
chr2	201798624	201798653	-	CDS,intron-Distal	5.33033	33.03786	HepG2	BCLAF1
chr2	201822122	201822173	-	CDS,intron-Distal,intron-Proximal	4.65221	31.70779	HepG2	BCLAF1
chr2	201778119	201778152	-	CDS,intron-Distal,intron-Proximal	4.83137	30.63629	HepG2	U2AF2
chr2	201798597	201798624	-	CDS,intron-Distal,intron-Proximal	4.56898	23.78468	HepG2	BCLAF1
chr2	201800426	201800507	-	CDS,intron-Distal	4.59601	22.28560	HepG2	BCLAF1
chr2	201822211	201822267	-	CDS,intron-Distal	3.85086	19.30627	HepG2	BCLAF1
chr2	201814338	201814368	-	CDS,intron-Distal,intron-Proximal	4.37434	18.07905	HepG2	PPIG
chr2	201813551	201813597	-	intron-Distal	4.99805	18.07576	HepG2	ILF3
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 91 entries

eCLIP assay for ORC2 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for ORC2 is not available on ENCORE database.
97 RBPs can affect the levels of ORC2.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for ORC2 is not available on ENCORE database.

97 RBPs can affect the gene expression of ORC2 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
ORC2	ENSG00000115942.4	1397.99910	2166.06710	-0.63170	20.02240	18.88350	HepG2	ZNF622
ORC2	ENSG00000115942.4	802.80670	1363.81060	-0.76450	15.52190	14.02730	K562	EIF2S2
ORC2	ENSG00000115942.4	1520.40400	2628.70870	-0.78990	15.14850	13.90440	HepG2	PUF60
ORC2	ENSG00000115942.4	1766.68980	2520.46670	-0.51260	13.93960	12.57460	HepG2	SLBP
ORC2	ENSG00000115942.4	1709.48200	2582.70660	-0.59530	13.54100	12.32920	HepG2	CELF1
ORC2	ENSG00000115942.4	1795.54570	2595.43470	-0.53160	12.46690	11.26810	HepG2	SRSF5
ORC2	ENSG00000115942.4	1121.61740	1670.36640	-0.57460	11.98340	10.79540	HepG2	HNRNPU
ORC2	ENSG00000115942.4	1230.24250	1734.67660	-0.49570	11.50960	10.33890	HepG2	SMN1
ORC2	ENSG00000115942.4	583.30040	1090.15040	-0.90220	9.75850	8.69240	K562	HNRNPC
ORC2	ENSG00000115942.4	742.99000	1211.33870	-0.70520	9.66970	8.60520	HepG2	RPS19
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 118 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for ORC2 is not available on ENCORE database.

18 RBPs can affect the splicing of ORC2 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
A3SS	ORC2	ENSG00000115942.4	chr2	-	201807407	201807563			201807407	201807500	201814276	201814366	0.11200	0.00000	0.00003	longer	K562	AQR
A5SS	ORC2	ENSG00000115942.4	chr2	-	201778550	201778715			201778653	201778715	201778017	201778136	0.08200	0.00000	0.00015	longer	K562	AQR
RI	ORC2	ENSG00000115942.4	chr2	-	201778017	201778715			201778017	201778136	201778653	201778715	0.11100	0.00000	0.00131	included	HepG2	DDX59
RI	ORC2	ENSG00000115942.4	chr2	-	201778017	201778715			201778017	201778136	201778653	201778715	0.20900	0.00000	0.00047	included	HepG2	PRPF4
RI	ORC2	ENSG00000115942.4	chr2	-	201778017	201778715			201778017	201778136	201778653	201778715	0.28200	0.00000	0.00000	included	HepG2	QKI
RI	ORC2	ENSG00000115942.4	chr2	-	201778017	201778715			201778017	201778136	201778653	201778715	0.21800	0.00000	0.00004	included	HepG2	TAF15
RI	ORC2	ENSG00000115942.4	chr2	-	201778017	201778715			201778017	201778136	201778653	201778715	-0.17500	0.00000	0.00015	excluded	K562	PTBP1
MXE	ORC2	ENSG00000115942.4	chr2	-	201805970	201806002	201807407	201807526	201802628	201802689	201814276	201814366	0.11800	0.00000	0.00001	1included	K562	AQR
SE	ORC2	ENSG00000115942.4	chr2	-	201791490	201791623			201785715	201785862	201796061	201796171	-0.30700	0.00001	0.00024	excluded	K562	AQR
RI	ORC2	ENSG00000115942.4	chr2	-	201778017	201778715			201778017	201778136	201778550	201778715	-0.16400	0.00001	0.00012	excluded	HepG2	U2AF2

Showing 1 to 10 of 37 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

ORC2

General Information

Functions

Localization

Domains (AlphaFold: ORC2)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for ORC2 is not avaliable on ENCORE database.

30 proteins are bound to ORC2 RNA:

eCLIP assay for ORC2 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for ORC2 is not available on ENCORE database.

97 RBPs can affect the gene expression of ORC2 :

The Knockdown/knockout RNA-Seq assay for ORC2 is not available on ENCORE database.

18 RBPs can affect the splicing of ORC2 :

The Knockdown/knockout RNA-Seq assay for ORC2 is not avaliable on ENCORE database.