MCL1

General Information

Gene Name : MCL1
Gene ID : ENSG00000143384.12
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: MCL1)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	MCL1	ENSG00000143384.12	84.01	74.27	79.14	ENCSR000AEF
HepG2	MCL1	ENSG00000143384.12	51.78	79.07	65.42	ENCSR985KAT
K562	MCL1	ENSG00000143384.12	106.34	106.17	106.25	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for MCL1 is not avaliable on ENCORE database.

Proteins bound to RNA

MCL1 RNA is bound by 31 proteins.

CanvasJS.com

eCLIP assay for MCL1 is not avaliable on ENCORE database.

31 proteins are bound to MCL1 RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr1	150549148	150549195	-	3'-UTR,intron-Distal	5.85869	400.00000	K562	PUM2
chr1	150549103	150549148	-	3'-UTR,intron-Distal	5.83423	78.29263	K562	PUM2
chr1	150547318	150547386	-	3'-UTR,intron-Distal	5.35593	62.34260	K562	UPF1
chr1	150551791	150551819	-	CDS,intron-Distal	4.82158	53.73123	HepG2	XPO5
chr1	150551819	150551841	-	CDS,intron-Distal	4.90380	43.49054	HepG2	XPO5
chr1	150551902	150551948	-	CDS,intron-Distal	5.31010	38.70459	K562	RBM15
chr1	150547200	150547255	-	3'-UTR,intron-Distal	4.11165	37.44154	K562	UPF1
chr1	150551859	150551892	-	CDS,intron-Distal	5.39615	34.94843	K562	RBM15
chr1	150551756	150551791	-	CDS,intron-Distal	4.80414	34.93727	HepG2	XPO5
chr1	150551993	150552064	-	5'-UTR,CDS,intron-Distal,intron-Proximal	3.56766	33.85319	K562	DDX3X
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 111 entries

eCLIP assay for MCL1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for MCL1 is not available on ENCORE database.
144 RBPs can affect the levels of MCL1.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for MCL1 is not available on ENCORE database.

144 RBPs can affect the gene expression of MCL1 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
MCL1	ENSG00000143384.8	17408.73230	6099.49470	1.51290	170.30410	167.96910	HepG2	SRFBP1
MCL1	ENSG00000143384.8	10857.61670	3668.16610	1.56550	153.59380	150.86750	HepG2	SRSF9
MCL1	ENSG00000143384.8	9330.87220	3934.25320	1.24580	130.37160	128.18460	HepG2	ZNF622
MCL1	ENSG00000143384.8	9330.31160	3453.66110	1.43370	126.78650	123.74300	HepG2	UTP3
MCL1	ENSG00000143384.8	9660.96770	4080.77700	1.24320	102.65400	100.36960	HepG2	ACO1
MCL1	ENSG00000143384.8	11137.15750	4958.64300	1.16730	67.51660	65.23630	HepG2	CELF1
MCL1	ENSG00000143384.8	7494.52880	4149.09110	0.85290	40.53790	38.95710	HepG2	PTBP1
MCL1	ENSG00000143384.8	10136.90520	5400.33880	0.90840	39.60410	38.09000	HepG2	RBM22
MCL1	ENSG00000143384.8	7719.38300	4501.55500	0.77800	33.86280	31.94880	K562	AGGF1
MCL1	ENSG00000143384.8	11290.96130	5627.55600	1.00450	33.74930	31.82490	HepG2	AUH
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 177 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for MCL1 is not available on ENCORE database.

7 RBPs can affect the splicing of MCL1 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	MCL1	ENSG00000143384.8	chr1	-	150550719	150550967	150547031	150549967	150551318	150552066	-0.16700	0.00000	0.00000	excluded	K562	AQR
SE	MCL1	ENSG00000143384.8	chr1	-	150550719	150550818	150549402	150549967	150551318	150552006	-0.06700	0.00003	0.00259	excluded	K562	TARDBP
SE	MCL1	ENSG00000143384.8	chr1	-	150550719	150550818	150549402	150549967	150551318	150552006	-0.09000	0.00011	0.00223	excluded	HepG2	U2AF2
SE	MCL1	ENSG00000143384.8	chr1	-	150550719	150550967	150547031	150549967	150551318	150552066	-0.05100	0.00020	0.00714	excluded	HepG2	HNRNPK
SE	MCL1	ENSG00000143384.8	chr1	-	150550719	150550818	150549402	150549967	150551318	150552006	-0.07100	0.00095	0.02013	excluded	K562	SF3B4
SE	MCL1	ENSG00000143384.8	chr1	-	150550719	150550818	150549402	150549967	150551318	150552006	-0.06600	0.00243	0.07144	excluded	K562	PRPF8
SE	MCL1	ENSG00000143384.8	chr1	-	150550719	150550818	150549402	150549967	150551318	150552006	-0.08000	0.00267	0.04587	excluded	HepG2	U2AF1

Showing 1 to 7 of 7 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

MCL1

General Information

Functions

Localization

Domains (AlphaFold: MCL1)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for MCL1 is not avaliable on ENCORE database.

31 proteins are bound to MCL1 RNA:

eCLIP assay for MCL1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for MCL1 is not available on ENCORE database.

144 RBPs can affect the gene expression of MCL1 :

The Knockdown/knockout RNA-Seq assay for MCL1 is not available on ENCORE database.

7 RBPs can affect the splicing of MCL1 :

The Knockdown/knockout RNA-Seq assay for MCL1 is not avaliable on ENCORE database.