SUCLG1

General Information

Gene Name : SUCLG1
Gene ID : ENSG00000163541.11
Essential Gene : Yes

Functions

Novel RBP

Localization(RBPImage: SUCLG1)

Nuclei
Nucleoplasm
Mutually Exclusive from Nucleolus
Cytoplasm
Compartment/Organelle
Mitochondria

Domains (AlphaFold: SUCLG1)

No checked domain (RRM, ZNF, KH, Helicase, Nuclease, dRBM or PUM_HD)

Antibody Validation

View validation images for all SUCLG1 antibodies

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	SUCLG1	ENSG00000163541.11	54.54	57.27	55.91	ENCSR000AEF
HepG2	SUCLG1	ENSG00000163541.11	74.47	93.76	84.12	ENCSR985KAT
K562	SUCLG1	ENSG00000163541.11	78.03	76.97	77.50	ENCSR000AEO

Assays

3 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Controls	Method	Note
knockdown followed by RNA-seq	SUCLG1-BGKLV25-K562	ENCSR101OPF	SUCLG1	K562	Released	ENCSR620PUP	shRNA	KD% = 59.1,61.5
knockdown followed by RNA-seq	SUCLG1-BGHLV23-HepG2	ENCSR810JYX	SUCLG1	HepG2	Released	ENCSR042QTH	shRNA	KD% = 76.6,68.2
RNA Bind-n-Seq	RBNS: SUCLG1	ENCSR474NYR	SUCLG1	cell-free sample	Released	ENCSR989YKV

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
SUCLG1	ENCAB020DGN	GTX109215	40023			Released, ENCODE3	BGHLV23-47, Released, ENCODE3	BGKLV25-57, Released, ENCODE3
SUCLG1		8071S	1			Submitted, ENCORE2	BGHLV23-47, Released, ENCODE3	BGKLV25-57, Submitted, ENCORE2

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project	Note
SUCLG1	K562	shRNA	ENCSR101OPF	ENCSR620PUP	SUCLG1-BGKLV25-57,SUCLG1-BGKLV25-58	NT_BGKLV25-1,NT_BGKLV25-2	59.1,61.5	Released	ENCODE3
SUCLG1	HepG2	shRNA	ENCSR810JYX	ENCSR042QTH	SUCLG1-BGHLV23-47,SUCLG1-BGHLV23-48	non-target-BGHLV23-1,non-target-BGHLV23-2	76.6,68.2	Released	ENCODE3

RNA Bind-n-Seqn

GeneName	gene_aliases	Status	Project	Note
SUCLG1	SUCLG1		Released	ENCODE4

Localization Image in HepG2

SUCLG1: Click to RBP Image Database

Nuclei

Nucleoplasm

Mutually Exclusive from Nucleolus

Cytoplasm

Compartment/Organelle

Mitochondria

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
SUCLG1	Product_ID: GTX109215 Lot_ID: 40023 Source: GeneTex Target Name: SUCLG1-human
SUCLG1	Product_ID: 8071S Lot_ID: 1 Source: Cell Signaling Technology Target Name: SUCLG1-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for SUCLG1 is not avaliable on ENCORE database.

The binding motifs of SUCLG1

Proteins bound to RNA

SUCLG1 RNA is bound by 18 proteins.

CanvasJS.com

eCLIP assay for SUCLG1 is not avaliable on ENCORE database.

18 proteins are bound to SUCLG1 RNA:

Show entries

Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr2	84686309	84686390	-	CDS,intron-Distal,intron-Proximal	4.34421	14.94351	K562	DDX3X
chr2	84676802	84676878	-	CDS,intron-Distal,intron-Proximal	3.32215	14.69203	K562	DDX3X
chr2	84660274	84660323	-	intron-Distal,intron-Proximal	4.60494	10.69368	K562	KHSRP
chr2	84668369	84668494	-	3'-UTR,CDS,intron-Distal,intron-Proximal	4.50434	10.54430	HepG2	G3BP1
chr2	84686295	84686309	-	CDS,intron-Distal	3.86120	10.05151	K562	DDX3X
chr2	84660323	84660340	-	intron-Distal,intron-Proximal	5.21788	8.49499	K562	KHSRP
chr2	84650740	84650862	-	3'-UTR,intron-Distal	3.06008	8.30744	HepG2	BCLAF1
chr2	84657953	84658061	-	intron-Distal	3.21948	7.90347	HepG2	SUGP2
chr2	84650732	84650795	-	3'-UTR,intron-Distal	5.48554	7.71888	HepG2	SUB1
chr2	84650720	84650867	-	3'-UTR,intron-Distal	3.98757	7.43667	HepG2	LARP4
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 39 entries

eCLIP assay for SUCLG1 is not avaliable on ENCORE database.

Diffrential Expression

8,170 differentially expressed genes after Knockdown/Knockout SUCLG1 protein.

CanvasJS.com

98 RBPs can affect the levels of SUCLG1.

CanvasJS.com

8,170 differentially expressed genes after Knockdown/Knockout SUCLG1 protein :

Only display 100 entries as example. Please click "View All" button to see all 8,170 entries.

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
SLC7A2	ENSG00000003989.12	1538.27240	6839.81140	-2.15260	268.69800	265.08330	HepG2	SUCLG1
ITGA3	ENSG00000005884.13	746.15070	138.72660	2.42710	75.64890	73.28540	HepG2	SUCLG1
CX3CL1	ENSG00000006210.6	4108.41920	2122.86040	0.95250	51.76820	49.68710	HepG2	SUCLG1
TMEM132A	ENSG00000006118.10	1661.62460	711.60030	1.22340	48.32130	46.29770	HepG2	SUCLG1
ADIPOR2	ENSG00000006831.9	2615.61620	4693.67870	-0.84360	44.24280	42.28930	HepG2	SUCLG1
ASB4	ENSG00000005981.8	1032.19000	192.90350	2.41970	40.09260	38.21430	HepG2	SUCLG1
PKD1	ENSG00000008710.13	1145.16500	449.84090	1.34800	36.69420	34.87650	HepG2	SUCLG1
CRLF1	ENSG00000006016.6	8223.69400	5190.26200	0.66390	34.98840	33.20510	HepG2	SUCLG1
CYP51A1	ENSG00000001630.11	3414.44480	5504.33570	-0.68890	32.78150	31.05050	HepG2	SUCLG1
TNFRSF12A	ENSG00000006327.9	1643.87980	740.17230	1.15110	31.65450	29.94470	HepG2	SUCLG1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 100 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

98 RBPs can affect the gene expression of SUCLG1 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
SUCLG1	ENSG00000163541.7	417.86670	4089.34870	-3.29080	246.17780	241.76640	K562	SUCLG1
SUCLG1	ENSG00000163541.7	230.95430	1761.00650	-2.93070	190.58690	187.34020	HepG2	SUCLG1
SUCLG1	ENSG00000163541.7	832.74320	1682.94500	-1.01500	33.97720	32.45880	HepG2	SRSF9
SUCLG1	ENSG00000163541.7	165.68220	609.04840	-1.87810	29.84560	27.91180	HepG2	CPSF6
SUCLG1	ENSG00000163541.7	1828.03220	993.57840	0.87950	28.47670	26.88520	HepG2	PUS1
SUCLG1	ENSG00000163541.7	3883.25130	1760.51630	1.14120	24.49460	22.50190	HepG2	CIRBP
SUCLG1	ENSG00000163541.7	890.94600	1548.48190	-0.79740	19.16960	17.72780	HepG2	SRSF5
SUCLG1	ENSG00000163541.7	1174.71800	2061.69400	-0.81150	18.54970	17.13240	HepG2	QKI
SUCLG1	ENSG00000163541.7	1091.26590	1859.30940	-0.76880	17.79230	16.54850	HepG2	TAF15
SUCLG1	ENSG00000163541.7	1312.71200	2118.51180	-0.69050	17.31880	16.18760	HepG2	NELFE
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 115 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

SUCLG1

General Information

Functions

Localization(RBPImage: SUCLG1)

Domains (AlphaFold: SUCLG1)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for SUCLG1 is not avaliable on ENCORE database.

18 proteins are bound to SUCLG1 RNA:

eCLIP assay for SUCLG1 is not avaliable on ENCORE database.

Diffrential Expression

8,170 differentially expressed genes after Knockdown/Knockout SUCLG1 protein :

98 RBPs can affect the gene expression of SUCLG1 :

The Knockdown/knockout RNA-Seq assay for SUCLG1 is not available on ENCORE database.

No RBPs affect the alternative splcing events of SUCLG1 on ENCORE database.

The Knockdown/knockout RNA-Seq assay for SUCLG1 is not avaliable on ENCORE database.