DAZAP1

General Information

Gene Name : DAZAP1
Gene ID : ENSG00000071626.16
Essential Gene : No

Functions

Splicing regulation
Translation regulation

Localization(RBPImage: DAZAP1)

Nuclei
Nucleoplasm
Mutually Exclusive from Nucleolus
Cytoplasm
Cytosolic
Mitotic-Apparatus (Spindle; Centrosomes)

Domains (AlphaFold: DAZAP1)

RRM

Antibody Validation

View validation images for all DAZAP1 antibodies

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	DAZAP1	ENSG00000071626.16	43.53	62.08	52.80	ENCSR000AEF
HepG2	DAZAP1	ENSG00000071626.16	83.78	60.20	71.99	ENCSR985KAT
K562	DAZAP1	ENSG00000071626.16	112.38	95.72	104.05	ENCSR000AEO

Assays

4 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Controls	Method	Note
knockdown followed by RNA-seq	DAZAP1-BGKLV13-K562	ENCSR907UTB	DAZAP1	K562	Released	ENCSR815CVQ	shRNA	KD% = 80.6,82.1
knockdown followed by RNA-seq	DAZAP1-BGHLV14-HepG2	ENCSR840QFR	DAZAP1	HepG2	Released	ENCSR003EKR	shRNA	KD% = 64.7,63.7
knockdown followed by RNA-seq	DAZAP1-BGHLV23-HepG2	ENCSR220TBR	DAZAP1	HepG2	Released	ENCSR042QTH	shRNA	KD% = 80.0,80.6
RNA Bind-n-Seq	RBNS: DAZAP1	ENCSR005ZRL	DAZAP1	cell-free sample	Released

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
DAZAP1	ENCAB490FGZ	A303-983A	1	Released, ENCODE3	Released, ENCODE3	BGHLV23-11, Released, ENCODE3	BGKLV13-37, Released, ENCODE3
DAZAP1	ENCAB657IXN	A303-984A	1	Released, ENCODE3	Released, ENCODE4	BGHLV23-11, Released, ENCODE3	BGKLV13-37, Released, ENCODE4
DAZAP1	ENCAB554PCA	A303-985A	1	Released, ENCODE3	Released, ENCODE4	BGHLV23-11, Released, ENCODE3	BGKLV13-37, Released, ENCODE4

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project
DAZAP1	K562	shRNA	ENCSR907UTB	ENCSR815CVQ	DAZAP1_BGKLV13_37,DAZAP1_BGKLV13_38	NT_BGKLV13_1,NT_BGKLV13_2	80.6,82.1	Released	ENCODE3
DAZAP1	K562	shRNA			BGKLV25-11,BGKLV25-12	BGKLV25-1,BGKLV25-2	see lv13,see lv13	NotSatisfied	ENCODE3
DAZAP1	HepG2	shRNA	ENCSR840QFR	ENCSR003EKR	DAZAP1_BGHLV14-7,DAZAP1_BGHLV14-8	NT_BGHLV14-1_1,NT_BGHLV14-2_1	64.7,63.7	Released	ENCODE3
DAZAP1	HepG2	shRNA	ENCSR220TBR	ENCSR042QTH	DAZAP1-BGHLV23-11,DAZAP1-BGHLV23-12	non-target-BGHLV23-1,non-target-BGHLV23-2	80.0,80.6	Released	ENCODE3

RNA Bind-n-Seqn

GeneName	gene_aliases	Status	Project	Note
DAZAP1	DAZAP1		Released	ENCODE3

Localization Image in HepG2

DAZAP1: Click to RBP Image Database

Nuclei

Nucleoplasm

Mutually Exclusive from Nucleolus

Cytoplasm

Cytosolic

Mitotic-Apparatus (Spindle; Centrosomes)

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
DAZAP1	Product_ID: A303-983A Lot_ID: 1 Source: Bethyl Labs Target Name: DAZAP1-human
DAZAP1	Product_ID: A303-984A Lot_ID: 1 Source: Bethyl Labs Target Name: DAZAP1-human
DAZAP1	Product_ID: A303-985A Lot_ID: 1 Source: Bethyl Labs Target Name: DAZAP1-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for DAZAP1 is not avaliable on ENCORE database.

The binding motifs of DAZAP1

Proteins bound to RNA

DAZAP1 RNA is bound by 88 proteins.

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eCLIP assay for DAZAP1 is not avaliable on ENCORE database.

88 proteins are bound to DAZAP1 RNA:

Show entries

Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr19	1435102	1435128	+	3'-UTR	5.33768	400.00000	K562	PABPC4
chr19	1420497	1420579	+	intron-Distal	6.27303	400.00000	K562	AGGF1
chr19	1435088	1435102	+	3'-UTR	5.84481	83.29618	K562	PABPC4
chr19	1420366	1420430	+	intron-Distal	5.80874	76.46380	K562	AGGF1
chr19	1419795	1419871	+	intron-Distal	4.05686	71.03513	K562	AGGF1
chr19	1424419	1424476	+	intron-Distal	5.52497	70.35349	HepG2	PCBP2
chr19	1410398	1410505	+	intron-Distal	6.36836	70.06162	K562	EWSR1
chr19	1419430	1419491	+	intron-Distal	4.59750	64.19257	K562	AGGF1
chr19	1424039	1424139	+	intron-Distal	6.01395	62.56166	HepG2	PCBP2
chr19	1410077	1410189	+	intron-Distal,intron-Proximal	6.10113	56.77969	K562	EWSR1
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 1,230 entries

eCLIP assay for DAZAP1 is not avaliable on ENCORE database.

Diffrential Expression

5,776 differentially expressed genes after Knockdown/Knockout DAZAP1 protein.

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103 RBPs can affect the levels of DAZAP1.

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5,776 differentially expressed genes after Knockdown/Knockout DAZAP1 protein :

Only display 100 entries as example. Please click "View All" button to see all 5,776 entries.

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
CYP51A1	ENSG00000001630.11	9646.43030	5178.82050	0.89730	63.89420	61.33480	HepG2	DAZAP1
CSDE1	ENSG00000009307.11	7796.27570	13369.93590	-0.77810	53.93250	51.53380	HepG2	DAZAP1
SLC7A2	ENSG00000003989.12	10477.47910	6435.22800	0.70310	41.36070	39.16550	HepG2	DAZAP1
CX3CL1	ENSG00000006210.6	3532.20930	1997.22560	0.82250	39.12460	36.99680	HepG2	DAZAP1
CLCN6	ENSG00000011021.17	3106.85350	1774.13880	0.80820	36.43170	34.34940	HepG2	DAZAP1
TSPAN9	ENSG00000011105.7	2180.40060	1216.62630	0.84160	32.38910	30.39270	HepG2	DAZAP1
TSPAN6	ENSG00000000003.10	1840.76570	3061.99830	-0.73420	29.59400	27.66490	HepG2	DAZAP1
TFPI	ENSG00000003436.10	19227.87150	10862.64630	0.82370	28.93460	27.02910	HepG2	DAZAP1
ANLN	ENSG00000011426.6	2304.57500	3664.97820	-0.66930	25.88600	24.05440	HepG2	DAZAP1
ADIPOR2	ENSG00000006831.9	6593.25380	4415.96620	0.57820	25.81710	23.98790	HepG2	DAZAP1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 100 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

103 RBPs can affect the gene expression of DAZAP1 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
DAZAP1	ENSG00000071626.12	956.31140	2268.78580	-1.24640	64.88330	62.30400	HepG2	DAZAP1
DAZAP1	ENSG00000071626.12	1625.80990	4689.44340	-1.52830	55.85680	53.36030	K562	HNRNPC
DAZAP1	ENSG00000071626.12	1231.61940	2271.55360	-0.88310	34.57970	32.72370	HepG2	ZC3H8
DAZAP1	ENSG00000071626.12	5579.03300	8068.84110	-0.53230	31.56510	29.50340	K562	NSUN2
DAZAP1	ENSG00000071626.12	4092.06240	7887.45890	-0.94670	26.29500	23.21190	K562	HNRNPL
DAZAP1	ENSG00000071626.12	1184.94560	2562.47770	-1.11270	24.61280	23.00030	HepG2	RPLP0
DAZAP1	ENSG00000071626.12	1409.01410	2282.10620	-0.69570	21.34850	19.93360	HepG2	PUS1
DAZAP1	ENSG00000071626.12	2420.89130	4756.30040	-0.97430	20.67790	18.51840	K562	CPSF6
DAZAP1	ENSG00000071626.12	4962.77650	7262.15970	-0.54930	19.73590	17.86700	K562	MTPAP
DAZAP1	ENSG00000071626.12	5184.80580	7961.99180	-0.61880	19.23610	17.24580	K562	SF3A3
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 128 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for DAZAP1 is not available on ENCORE database.

34 RBPs can affect the splicing of DAZAP1 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	FDR	is_included	Cell Line	Affected by RBP
SE	DAZAP1	ENSG00000071626.12	chr19	+	1422346	1422395	1421149	1421257	1428840	1428902	-0.09500	0.00000	excluded	K562	SF3B4
SE	DAZAP1	ENSG00000071626.12	chr19	+	1421146	1421257	1418664	1418730	1428840	1428994	-0.09200	0.00000	excluded	K562	AKAP8L
SE	DAZAP1	ENSG00000071626.12	chr19	+	1425876	1425959	1422276	1422395	1428840	1428994	-0.08300	0.00000	excluded	K562	AQR
SE	DAZAP1	ENSG00000071626.12	chr19	+	1421146	1421257	1418664	1418730	1428840	1428994	0.07700	0.00000	included	K562	FXR1
SE	DAZAP1	ENSG00000071626.12	chr19	+	1425876	1425959	1422346	1422395	1428840	1428994	-0.05700	0.00001	excluded	K562	SUPV3L1
SE	DAZAP1	ENSG00000071626.12	chr19	+	1421146	1421257	1418664	1418730	1428840	1428994	-0.10900	0.00000	excluded	K562	PUS1
SE	DAZAP1	ENSG00000071626.12	chr19	+	1425876	1425959	1422346	1422395	1428840	1428994	-0.12100	0.00000	excluded	HepG2	TIAL1
SE	DAZAP1	ENSG00000071626.12	chr19	+	1421146	1421257	1418664	1418730	1428840	1428994	-0.06600	0.00000	excluded	K562	UTP18
SE	DAZAP1	ENSG00000071626.12	chr19	+	1425876	1425959	1421146	1421257	1428840	1428994	-0.07700	0.00015	excluded	K562	HNRNPU
SE	DAZAP1	ENSG00000071626.12	chr19	+	1422346	1422584	1421149	1421257	1428840	1428994	-0.07200	0.00000	excluded	K562	RBM15

Showing 1 to 10 of 64 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

DAZAP1

General Information

Functions

Localization(RBPImage: DAZAP1)

Domains (AlphaFold: DAZAP1)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for DAZAP1 is not avaliable on ENCORE database.

88 proteins are bound to DAZAP1 RNA:

eCLIP assay for DAZAP1 is not avaliable on ENCORE database.

Diffrential Expression

5,776 differentially expressed genes after Knockdown/Knockout DAZAP1 protein :

103 RBPs can affect the gene expression of DAZAP1 :

The Knockdown/knockout RNA-Seq assay for DAZAP1 is not available on ENCORE database.

34 RBPs can affect the splicing of DAZAP1 :

The Knockdown/knockout RNA-Seq assay for DAZAP1 is not avaliable on ENCORE database.