FDPS

General Information

Gene Name : FDPS
Gene ID : ENSG00000160752.14
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: FDPS)

Not Available

Antibody Validation

Bethyl Labs: A305-045A

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	FDPS	ENSG00000160752.14	346.55	317.73	332.14	ENCSR000AEF
HepG2	FDPS	ENSG00000160752.14	255.52	298.93	277.23	ENCSR985KAT
K562	FDPS	ENSG00000160752.14	226.41	220.69	223.55	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
FDPS		A305-045A	1				BGHcLV41-69, Submitted, ENCORE2	BGKcLV40-49, Submitted, ENCORE2

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project	Note
FDPS	K562	CRISPR			FDPS-BGKcLV40-49,FDPS-BGKcLV40-50	NT-BGKcLV40-1,NT-BGKcLV40-2	59.8,60.9	Submitting	ENCORE2
FDPS	HepG2	CRISPR			FDPS-BGHcLV41-69,FDPS-BGHcLV41-70	NT-BGHcLV41-1,NT-BGHcLV41-2	70.8,77.0	Submitting	ENCORE2

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
FDPS	Product_ID: A305-045A Lot_ID: 1 Source: Bethyl Labs Target Name: FDPS-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for FDPS is not avaliable on ENCORE database.

Proteins bound to RNA

FDPS RNA is bound by 46 proteins.

CanvasJS.com

eCLIP assay for FDPS is not avaliable on ENCORE database.

46 proteins are bound to FDPS RNA:

Show entries

Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr1	155279754	155279858	+	5'-UTR,CDS,intron-Distal,intron-Proximal	4.23890	37.53551	HepG2	EFTUD2
chr1	155281958	155282073	+	CDS,intron-Proximal	3.42970	34.67129	K562	SF3B4
chr1	155288077	155288136	+	CDS,intron-Proximal	4.32621	33.23169	HepG2	PRPF8
chr1	155289419	155289444	+	CDS	4.59490	32.32840	K562	LIN28B
chr1	155278744	155278848	+	5'-UTR,intron-Proximal	3.80789	32.07235	HepG2	EFTUD2
chr1	155289444	155289468	+	CDS	4.82084	30.98986	K562	LIN28B
chr1	155287902	155287959	+	intron-Proximal	6.18039	29.90936	K562	SF3B4
chr1	155282225	155282332	+	intron-Distal,intron-Proximal	4.62282	28.91994	K562	FUS
chr1	155288400	155288455	+	intron-Proximal	4.25715	25.60064	HepG2	SF3A3
chr1	155289723	155289761	+	intron-Proximal	5.09731	24.37808	K562	AQR
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 165 entries

eCLIP assay for FDPS is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for FDPS is not available on ENCORE database.
182 RBPs can affect the levels of FDPS.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for FDPS is not available on ENCORE database.

182 RBPs can affect the gene expression of FDPS :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
FDPS	ENSG00000160752.10	4056.07810	15910.81110	-1.97190	152.42200	150.03920	HepG2	NELFE
FDPS	ENSG00000160752.10	4727.90450	14818.17680	-1.64810	148.72360	145.76530	HepG2	RECQL
FDPS	ENSG00000160752.10	4534.64090	15536.49910	-1.77660	132.98310	130.96390	HepG2	SRSF1
FDPS	ENSG00000160752.10	4479.10650	14296.37300	-1.67440	125.45820	123.18730	HepG2	PTBP1
FDPS	ENSG00000160752.10	4906.19110	14885.06140	-1.60120	95.64270	93.12520	HepG2	SF3B4
FDPS	ENSG00000160752.10	3053.22420	16757.71400	-2.45640	88.34580	86.07410	HepG2	AKAP1
FDPS	ENSG00000160752.10	4722.30520	12639.52640	-1.42040	85.78370	83.60990	HepG2	SRSF9
FDPS	ENSG00000160752.10	3216.38560	9504.61180	-1.56320	67.23020	65.13340	HepG2	PUM1
FDPS	ENSG00000160752.10	3991.97910	7950.13590	-0.99390	61.73240	59.49570	HepG2	UTP3
FDPS	ENSG00000160752.10	13800.71010	6685.39330	1.04560	59.42870	57.81690	HepG2	SSB
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 237 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for FDPS is not available on ENCORE database.

62 RBPs can affect the splicing of FDPS :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	FDR	is_included	Cell Line	Affected by RBP
SE	FDPS	ENSG00000160752.10	chr1	+	155289584	155289719	155289405	155289479	155290199	155290456	-0.06600	0.00000	excluded	K562	SRSF1
SE	FDPS	ENSG00000160752.10	chr1	+	155289584	155289719	155289401	155289479	155290199	155290456	-0.05100	0.00000	excluded	K562	FTO
SE	FDPS	ENSG00000160752.10	chr1	+	155279833	155279996	155278608	155278756	155282045	155282195	-0.05200	0.00015	excluded	K562	PRPF8
SE	FDPS	ENSG00000160752.10	chr1	+	155289584	155289719	155289405	155289479	155290199	155290457	-0.16300	0.00000	excluded	K562	PRPF8
SE	FDPS	ENSG00000160752.10	chr1	+	155289539	155289719	155289401	155289479	155290199	155290457	-0.14400	0.00000	excluded	K562	FMR1
SE	FDPS	ENSG00000160752.10	chr1	+	155279579	155279756	155278642	155278756	155279833	155279996	0.24800	0.00000	included	HepG2	HNRNPK
SE	FDPS	ENSG00000160752.10	chr1	+	155279579	155279756	155278642	155278756	155279833	155279996	0.11000	0.00018	included	HepG2	TRA2A
SE	FDPS	ENSG00000160752.10	chr1	+	155279579	155279756	155278642	155278756	155279833	155279975	0.13000	0.00050	included	HepG2	DDX59
SE	FDPS	ENSG00000160752.10	chr1	+	155279579	155279756	155278642	155278756	155279833	155279996	0.20700	0.00010	included	HepG2	U2AF2
SE	FDPS	ENSG00000160752.10	chr1	+	155289584	155289719	155289401	155289479	155290199	155290456	-0.05800	0.00000	excluded	K562	METAP2

Showing 1 to 10 of 123 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

FDPS

General Information

Functions

Localization

Domains (AlphaFold: FDPS)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for FDPS is not avaliable on ENCORE database.

46 proteins are bound to FDPS RNA:

eCLIP assay for FDPS is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for FDPS is not available on ENCORE database.

182 RBPs can affect the gene expression of FDPS :

The Knockdown/knockout RNA-Seq assay for FDPS is not available on ENCORE database.

62 RBPs can affect the splicing of FDPS :

The Knockdown/knockout RNA-Seq assay for FDPS is not avaliable on ENCORE database.