TOB2

General Information

Gene Name       : TOB2
Gene ID             : ENSG00000183864.4
Essential Gene : No

Functions

Localization

Domains (AlphaFold: TOB2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TOB2ENSG00000183864.46.9511.999.47ENCSR000AEF
HepG2TOB2ENSG00000183864.417.3314.8416.09ENCSR985KAT
K562TOB2ENSG00000183864.48.497.828.16ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
TOB2Ribo-STAMP-293TshRNABGRSLV05-15,BGRSLV05-16BGRSLV05-1,BGRSLV05-2NotSatisfiedENCORE2
TOB2293TshRNATOB2-BG293LV03-19,TOB2-BG293LV03-20NT-BG293LV03-1,NT-BG293LV03-2,SubmittingENCORE2
TOB2293TshRNABG293LV03-21,BG293LV03-22BG293LV03-1,BG293LV03-2NotSatisfiedENCORE2
TOB2293TshRNATOB2-BG293LV06-117B,TOB2-BG293LV06-118BNT-BG293LV06-1B,NT-BG293LV06-2B,SequencedENCORE2


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TOB2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • TOB2 RNA is bound by 15 proteins.  







eCLIP assay for TOB2 is not avaliable on ENCORE database.





15 proteins are bound to TOB2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr224182965041829677-3'-UTR,intron-Distal4.121373.31330K562UPF1
chr224183101541831051-3'-UTR,intron-Distal4.680705.63383K562UPF1
chr224182969341829743-3'-UTR,intron-Distal3.786454.87320K562UPF1
chr224183187541831937-3'-UTR,intron-Distal3.913923.35877HepG2UPF1
chr224183128641831376-3'-UTR,intron-Distal3.906957.13548K562UPF1
chr224183197941832020-3'-UTR,intron-Distal4.240364.48843K562TIA1
chr224183151741831565-3'-UTR,intron-Distal5.134226.29945HepG2XPO5
chr224183167141831744-3'-UTR,intron-Distal3.992093.51789K562IGF2BP2
chr224183216541832209-3'-UTR,intron-Distal4.085026.29084HepG2RBM15
chr224183042241830471-3'-UTR,intron-Distal3.247506.13685K562UPF1
chr224183168741831786-3'-UTR,intron-Distal3.243344.69164HepG2IGF2BP1
chr224183166741831801-3'-UTR,intron-Distal3.458074.39411HepG2IGF2BP3
chr224184259041842665-5'-UTR,intron-Distal3.621788.58457HepG2DDX3X
chr224184267241842796-5'-UTR,intron-Distal,intron-Proximal5.7548713.97750HepG2DDX3X
chr224184238641842451-5'-UTR,intron-Distal3.122163.99819HepG2SRSF1
chr224184271941842801-5'-UTR,intron-Distal,intron-Proximal4.981216.68186HepG2NCBP2
chr224184233141842387-5'-UTR,intron-Distal3.453587.35853HepG2PRPF8
chr224183318041833232-CDS,intron-Distal4.652173.27329HepG2RBM15
chr224183247641832509-CDS,intron-Distal5.173605.42508HepG2RBM15
chr224183272941832758-CDS,intron-Distal4.086343.51664K562RBM15
chr224183324241833298-CDS,intron-Distal4.638115.85529K562RBM15
chr224183249341832535-CDS,intron-Distal4.849626.89039K562RBM15
chr224183236441832437-CDS,intron-Distal3.878493.25175K562YBX3
chr224183312541833177-CDS,intron-Distal3.523583.34231K562RBM15
chr224183239241832438-CDS,intron-Distal4.958047.93248K562RBM15
chr224183245441832507-CDS,intron-Distal3.991304.55582HepG2SLTM
chr224183239141832448-CDS,intron-Distal3.470895.12765HepG2RBM15
chr224183245041832493-CDS,intron-Distal5.4666410.73550K562RBM15
chr224184206841842135-intron-Distal3.483705.44142HepG2PCBP2
chr224184214841842258-intron-Distal3.284428.38251HepG2PCBP2
chr224184219841842240-intron-Distal4.444413.92947HepG2DDX59
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TOB2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TOB2 is not available on ENCORE database.

  • 89 RBPs can affect the levels of TOB2.  








The Knockdown/knockout RNA-Seq assay for TOB2 is not available on ENCORE database.





89 RBPs can affect the gene expression of TOB2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TOB2ENSG00000183864.41367.070501080.676700.339104.559703.81620HepG2ACO1
TOB2ENSG00000183864.41198.08430919.085500.382402.851401.84090HepG2ADAR
TOB2ENSG00000183864.4650.671201085.63800-0.7385014.0600012.51400HepG2AKAP8L
TOB2ENSG00000183864.41454.680001088.946100.417703.191702.34740HepG2ASCC1
TOB2ENSG00000183864.41237.434501583.64210-0.355902.964701.51100HepG2ATP5C1
TOB2ENSG00000183864.41028.120701580.29790-0.6202012.6489011.36870HepG2AUH
TOB2ENSG00000183864.4651.43770897.17720-0.461803.415202.42020HepG2BCLAF1
TOB2ENSG00000183864.4880.845801175.80700-0.416703.980403.07900HepG2CALR
TOB2ENSG00000183864.41909.120001034.576300.8838013.1099011.56350HepG2CIRBP
TOB2ENSG00000183864.4980.350101314.12680-0.422703.382902.63090HepG2CPSF6
TOB2ENSG00000183864.41719.510901241.485900.469807.089406.14970HepG2CELF1
TOB2ENSG00000183864.41287.64110999.407000.365504.533803.50110HepG2DDX19B
TOB2ENSG00000183864.41054.73850809.139400.382303.016102.31020HepG2DDX21
TOB2ENSG00000183864.4323.51950768.97110-1.2491017.9466015.15890HepG2DDX28
TOB2ENSG00000183864.41005.421601260.69780-0.326401.985701.44700HepG2DDX3X
TOB2ENSG00000183864.41441.038501033.878700.478907.466406.45510HepG2DKC1
TOB2ENSG00000183864.41124.42040917.293700.293603.502802.78370HepG2DNAJC2
TOB2ENSG00000183864.4598.096701041.07970-0.799608.367807.37470HepG2EIF2S1
TOB2ENSG00000183864.4948.93710708.199400.422102.769101.86560HepG2EIF3D
TOB2ENSG00000183864.4947.41650764.324900.309702.322901.33150HepG2EIF3G
TOB2ENSG00000183864.41478.807501160.860200.349102.396301.75060HepG2FXR1
TOB2ENSG00000183864.41489.193001143.240900.381302.853501.94710HepG2G3BP2
TOB2ENSG00000183864.4410.53500785.36270-0.935906.844505.10120HepG2GRSF1
TOB2ENSG00000183864.41151.28440934.347400.301102.078201.50910HepG2HNRNPA1
TOB2ENSG00000183864.41037.373601226.90100-0.242102.365701.49300HepG2HNRNPA2B1
TOB2ENSG00000183864.4604.268201039.28370-0.782309.654508.42540HepG2HNRNPC
TOB2ENSG00000183864.41010.814801216.23760-0.266902.842702.16150HepG2HNRNPL
TOB2ENSG00000183864.4966.403101421.60110-0.556805.409804.55920HepG2HNRNPLL
TOB2ENSG00000183864.4626.217901032.41290-0.7213013.8576012.58900HepG2HNRNPU
TOB2ENSG00000183864.41752.615801094.571400.679007.886606.80750HepG2IGF2BP2
TOB2ENSG00000183864.4879.334401054.57650-0.262203.044602.27850HepG2ILF2
TOB2ENSG00000183864.4509.50110717.66390-0.494204.140302.15050HepG2CCAR2
TOB2ENSG00000183864.41814.267401161.265700.643606.929505.90560HepG2MAGOH
TOB2ENSG00000183864.4873.306501449.88320-0.731405.341103.96900HepG2MTPAP
TOB2ENSG00000183864.4881.967201204.30670-0.449404.205202.70750HepG2NAA15
TOB2ENSG00000183864.4981.469901323.87460-0.431805.430104.36840HepG2NOL12
TOB2ENSG00000183864.41618.905201154.216800.488008.716307.73780HepG2PCBP1
TOB2ENSG00000183864.4524.97870782.96240-0.576704.852403.81550HepG2PRPF8
TOB2ENSG00000183864.41390.798001174.497000.243802.430901.91240HepG2PTBP1
TOB2ENSG00000183864.41658.234301341.406400.305803.463002.81440HepG2PUM1
TOB2ENSG00000183864.41271.738601100.718900.208301.951201.41470HepG2PUS1
TOB2ENSG00000183864.4844.151101271.92780-0.591408.248907.25790HepG2QKI
TOB2ENSG00000183864.42039.845501516.500800.427606.382705.67390HepG2RBM22
TOB2ENSG00000183864.41083.31990777.936300.477603.058801.94340HepG2RCC2
TOB2ENSG00000183864.41849.785901307.070600.500908.652707.79340HepG2NELFE
TOB2ENSG00000183864.41501.701101217.416300.302703.608202.91720HepG2RECQL
TOB2ENSG00000183864.4831.766201151.87180-0.469704.353603.52620HepG2RPLP0
TOB2ENSG00000183864.41191.71590883.502400.431603.216102.35240HepG2RPS2
TOB2ENSG00000183864.4601.76770774.48170-0.364002.169201.46410HepG2RRP9
TOB2ENSG00000183864.4742.16930919.41240-0.309003.123402.44730HepG2SAFB2
TOB2ENSG00000183864.41479.31070587.776101.331505.088403.12650HepG2SF1
TOB2ENSG00000183864.41927.199401407.095000.453704.584703.69340HepG2SF3B1
TOB2ENSG00000183864.41006.87910525.039200.939302.967001.59950HepG2SNRNP200
TOB2ENSG00000183864.42116.998601712.829700.305504.759904.15380HepG2SRFBP1
TOB2ENSG00000183864.41570.833301247.639900.332204.008203.28000HepG2SRSF5
TOB2ENSG00000183864.4547.424701038.36050-0.9236020.9249019.66610HepG2SRSF9
TOB2ENSG00000183864.42188.073701487.138000.5570013.1664012.21270HepG2SSB
TOB2ENSG00000183864.41837.319801418.977200.372705.784804.94520HepG2SUCLG1
TOB2ENSG00000183864.4937.479101196.57620-0.352103.184202.18120HepG2SUPT6H
TOB2ENSG00000183864.4677.072801010.68710-0.578004.994804.12780HepG2SUPV3L1
TOB2ENSG00000183864.42115.978601381.889100.614602.586901.55140HepG2TBRG4
TOB2ENSG00000183864.4638.865701012.14860-0.6638011.6838010.64130HepG2TRIM56
TOB2ENSG00000183864.42202.913701515.909200.539105.870204.97140HepG2U2AF1
TOB2ENSG00000183864.41450.73460611.087001.247204.580103.29220HepG2U2AF2
TOB2ENSG00000183864.4432.07650596.98330-0.466403.260002.43740HepG2UCHL5
TOB2ENSG00000183864.41880.714901301.752500.5307010.268309.23130HepG2UTP3
TOB2ENSG00000183864.41427.745501177.739100.277603.527002.78280HepG2ZC3H8
TOB2ENSG00000183864.41032.758601482.89610-0.5219011.3261010.40440HepG2ZNF622
TOB2ENSG00000183864.42032.30280784.069601.3740032.1955030.39140K562AQR
TOB2ENSG00000183864.4674.99390505.450300.417202.530101.53110K562CCAR1
TOB2ENSG00000183864.41195.21250769.458700.635303.509102.28910K562CNOT7
TOB2ENSG00000183864.41264.01230992.030700.349503.704202.41340K562CPEB4
TOB2ENSG00000183864.4386.45290507.59590-0.393402.910801.55190K562DDX27
TOB2ENSG00000183864.4875.34410590.675400.567404.000902.72910K562EIF3D
TOB2ENSG00000183864.4436.13440338.582700.365202.441101.69180K562EIF3G
TOB2ENSG00000183864.4713.75180478.703900.576205.149004.02740K562EIF4A3
TOB2ENSG00000183864.4610.23980431.090900.501304.761703.17530K562EIF4B
TOB2ENSG00000183864.41436.494901063.243300.434005.880004.53270K562EIF4G2
TOB2ENSG00000183864.4906.40450703.844700.364802.893801.59410K562EXOSC5
TOB2ENSG00000183864.4329.77990454.12790-0.461602.456101.40420K562FKBP4
TOB2ENSG00000183864.4697.74060497.830500.486904.746003.98230K562FXR1
TOB2ENSG00000183864.4602.001601076.09830-0.838007.580006.31350K562GRSF1
TOB2ENSG00000183864.41214.29790927.835600.388103.510002.30260K562HNRNPL
TOB2ENSG00000183864.4672.56310474.637500.502704.214803.17350K562MAGOH
TOB2ENSG00000183864.41116.96420907.089400.300202.330101.50790K562MBNL1
TOB2ENSG00000183864.4505.33770770.50120-0.608507.803206.50590K562MTPAP
TOB2ENSG00000183864.41052.06550856.076700.297303.504702.67440K562NSUN2
TOB2ENSG00000183864.4856.15130686.666000.318202.158301.45130K562POLR2G
TOB2ENSG00000183864.41625.166101233.909600.397304.635803.22640K562PUM1
TOB2ENSG00000183864.4541.51260756.70400-0.482703.545902.94290K562PUS1
TOB2ENSG00000183864.4669.41260442.140200.598305.321204.11120K562RBM22
TOB2ENSG00000183864.4593.91630427.852000.473003.695902.55050K562RCC2
TOB2ENSG00000183864.4788.18400611.982400.364902.534701.50040K562SAFB
TOB2ENSG00000183864.4403.65250292.876700.462703.006502.11410K562SF3B4
TOB2ENSG00000183864.41188.48380865.475400.457507.063205.64390K562SRPK2
TOB2ENSG00000183864.4698.65940425.800900.714305.779804.15260K562SRSF4
TOB2ENSG00000183864.4655.61030457.521000.518903.430902.63920K562TARDBP
TOB2ENSG00000183864.4559.70770441.335800.342702.125601.41650K562TIA1
TOB2ENSG00000183864.4614.23010451.005300.445502.637301.72620K562TIAL1
TOB2ENSG00000183864.4575.36520433.127600.409602.465701.44710K562TRA2A
TOB2ENSG00000183864.4611.56260479.174600.351802.153601.33530K562TRIM56
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TOB2 is not available on ENCORE database.





1 RBPs can affect the splicing of TOB2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETOB2ENSG00000183864.4chr22-4184129641841425418294954183341141842382418430270.242000.000250.00634includedHepG2U2AF1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TOB2 is not avaliable on ENCORE database.