SYPL1

General Information

Gene Name       : SYPL1
Gene ID             : ENSG00000008282.8
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SYPL1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SYPL1ENSG00000008282.865.4953.3359.41ENCSR000AEF
HepG2SYPL1ENSG00000008282.825.3546.1835.77ENCSR985KAT
K562SYPL1ENSG00000008282.851.9754.7953.38ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SYPL1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • SYPL1 RNA is bound by 15 proteins.  







eCLIP assay for SYPL1 is not avaliable on ENCORE database.





15 proteins are bound to SYPL1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr7105731078105731105-3'-UTR,intron-Distal4.067566.89197K562PUM2
chr7105731829105731874-3'-UTR,intron-Distal,intron-Proximal4.636975.03175K562IGF2BP1
chr7105732214105732238-3'-UTR,intron-Distal4.974069.14311K562PUM2
chr7105732266105732360-3'-UTR,CDS,intron-Distal5.6227010.62670HepG2SND1
chr7105731829105731858-3'-UTR,intron-Distal,intron-Proximal3.4094210.94245K562PUM2
chr7105731430105731497-3'-UTR,intron-Distal4.398444.00100K562TIA1
chr7105732015105732055-3'-UTR,intron-Distal,intron-Proximal5.3105249.15172K562PUM2
chr7105732206105732309-3'-UTR,CDS,intron-Distal4.349575.99081K562IGF2BP1
chr7105732176105732243-3'-UTR,intron-Distal5.5195323.68384K562PABPC4
chr7105731436105731487-3'-UTR,intron-Distal3.754234.69728HepG2DDX55
chr7105732277105732316-3'-UTR,CDS,intron-Distal3.121145.74118K562YBX3
chr7105732255105732309-3'-UTR,CDS,intron-Distal6.1249014.23783K562SND1
chr7105732018105732058-3'-UTR,intron-Distal,intron-Proximal4.758804.37192HepG2FUBP3
chr7105731019105731075-3'-UTR,intron-Distal4.5717915.39740K562PUM2
chr7105731425105731483-3'-UTR,intron-Distal4.073828.36483HepG2FUBP3
chr7105731438105731506-3'-UTR,intron-Distal4.359034.49293HepG2TIAL1
chr7105732310105732370-3'-UTR,CDS,intron-Distal4.095208.16865K562LIN28B
chr7105732309105732384-3'-UTR,CDS,intron-Distal4.5234515.03214K562SND1
chr7105731874105731945-3'-UTR,intron-Distal,intron-Proximal4.927796.56044K562IGF2BP1
chr7105732055105732114-3'-UTR,intron-Distal,intron-Proximal4.7073336.06866K562PUM2
chr7105752612105752739-5'-UTR,CDS,intron-Distal,intron-Proximal3.624186.15884HepG2PCBP2
chr7105752636105752755-5'-UTR,CDS,intron-Distal,intron-Proximal3.422829.00262K562PCBP1
chr7105752606105752702-5'-UTR,CDS,intron-Distal,intron-Proximal3.057445.19025K562DROSHA
chr7105738149105738217-CDS,intron-Distal3.818265.23222HepG2SND1
chr7105733392105733457-CDS,intron-Distal,intron-Proximal5.012697.33420HepG2SND1
chr7105733393105733449-CDS,intron-Distal,intron-Proximal4.202829.96581K562SND1
chr7105733449105733492-CDS,intron-Distal4.7563412.27219K562SND1
chr7105738309105738343-CDS,intron-Distal,intron-Proximal3.329028.88089K562YBX3
chr7105733501105733560-CDS,intron-Distal4.172949.49432HepG2SND1
chr7105733492105733582-CDS,intron-Distal4.3334223.03419K562SND1
chr7105739603105739615-CDS,intron-Distal,intron-Proximal3.498653.34065K562IGF2BP1
chr7105738135105738187-CDS,intron-Distal,intron-Proximal5.4751518.76333K562SND1
chr7105738187105738292-CDS,intron-Distal4.8086521.09734K562SND1
chr7105739603105739619-CDS,intron-Distal,intron-Proximal3.977517.28749K562YBX3
chr7105738175105738229-CDS,intron-Distal3.986883.45860K562TIA1
chr7105738299105738344-CDS,intron-Distal,intron-Proximal3.174846.16271K562SND1
chr7105739452105739568-intron-Distal,intron-Proximal3.288113.47285K562PRPF8
chr7105752570105752586-intron-Distal,intron-Proximal4.116076.01372K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SYPL1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SYPL1 is not available on ENCORE database.

  • 86 RBPs can affect the levels of SYPL1.  








The Knockdown/knockout RNA-Seq assay for SYPL1 is not available on ENCORE database.





86 RBPs can affect the gene expression of SYPL1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SYPL1ENSG00000008282.3702.109101153.22820-0.715907.454105.92200HepG2ADAR
SYPL1ENSG00000008282.32316.250401988.417100.220102.002601.40160HepG2AUH
SYPL1ENSG00000008282.31441.541201158.243500.315602.109601.32080HepG2BCLAF1
SYPL1ENSG00000008282.31694.094101157.685800.549205.358104.32890HepG2CALR
SYPL1ENSG00000008282.32631.658201969.684500.417903.776002.88240HepG2CIRBP
SYPL1ENSG00000008282.31532.672501343.193600.190301.989301.41360HepG2CKAP4
SYPL1ENSG00000008282.31276.478401008.912400.339302.384701.73990HepG2CPSF6
SYPL1ENSG00000008282.32122.139801808.983400.230202.382801.77800HepG2CELF1
SYPL1ENSG00000008282.33198.836102400.220200.414302.635702.02340HepG2DDX3X
SYPL1ENSG00000008282.31602.903701145.688600.484402.229901.35540HepG2DDX59
SYPL1ENSG00000008282.3813.871001163.26970-0.515304.784103.47680HepG2DDX5
SYPL1ENSG00000008282.31447.060202061.79400-0.510804.196403.44760HepG2DDX6
SYPL1ENSG00000008282.3948.559601150.90220-0.279002.756402.10630HepG2DNAJC2
SYPL1ENSG00000008282.31382.133401013.845100.447002.814401.69930HepG2AGO1
SYPL1ENSG00000008282.3996.68020754.520400.401502.630701.74650HepG2EIF3D
SYPL1ENSG00000008282.31405.308502190.47170-0.640406.252305.29740HepG2EIF4A3
SYPL1ENSG00000008282.3680.782302132.69060-1.6474026.9618024.98660HepG2EIF4B
SYPL1ENSG00000008282.31383.607801098.234300.333102.673101.59890HepG2ESF1
SYPL1ENSG00000008282.32879.662602282.932200.334905.452704.65650HepG2ETF1
SYPL1ENSG00000008282.3598.564401090.81220-0.865809.065207.01590HepG2FKBP4
SYPL1ENSG00000008282.31632.383102210.02910-0.437103.855603.04850HepG2FXR1
SYPL1ENSG00000008282.31576.627902050.16030-0.378902.691602.03480HepG2G3BP1
SYPL1ENSG00000008282.3474.566401143.72690-1.2691017.4423015.97250HepG2GPKOW
SYPL1ENSG00000008282.3789.554901216.59940-0.623704.189702.82280HepG2GRSF1
SYPL1ENSG00000008282.3634.064001172.43730-0.8868013.2557012.01270HepG2HNRNPA1
SYPL1ENSG00000008282.31560.185902075.89320-0.412003.802802.99480HepG2HNRNPK
SYPL1ENSG00000008282.31460.541201771.94640-0.278804.167803.35350HepG2HNRNPL
SYPL1ENSG00000008282.31526.705101091.475500.484004.434003.65380HepG2HNRNPLL
SYPL1ENSG00000008282.31072.659301295.45000-0.272302.309201.75060HepG2HNRNPU
SYPL1ENSG00000008282.31341.51960964.666700.475703.232101.89850HepG2HSPD1
SYPL1ENSG00000008282.3902.230301106.91140-0.295002.233201.57850HepG2IGF2BP1
SYPL1ENSG00000008282.3730.834001323.26810-0.8565013.2013011.73300HepG2ILF2
SYPL1ENSG00000008282.31477.688102096.08020-0.504403.558902.40340HepG2KHSRP
SYPL1ENSG00000008282.31048.454701228.09400-0.228202.419601.46570HepG2KIF1C
SYPL1ENSG00000008282.31623.448202210.80040-0.445503.826203.05530HepG2MAGOH
SYPL1ENSG00000008282.31624.129502223.18450-0.453003.528302.82400HepG2MATR3
SYPL1ENSG00000008282.31415.393601036.206500.449804.933203.87410HepG2MSI2
SYPL1ENSG00000008282.31656.103201961.95790-0.244502.780702.17320HepG2PCBP1
SYPL1ENSG00000008282.3943.149001155.44690-0.292902.524401.81710HepG2PPIL4
SYPL1ENSG00000008282.31369.491701996.41730-0.5438010.186509.26490HepG2PTBP1
SYPL1ENSG00000008282.32276.780901954.511200.220103.070302.45330HepG2PUM1
SYPL1ENSG00000008282.3932.339001368.36690-0.5535010.746309.66830HepG2PUS1
SYPL1ENSG00000008282.3720.325202162.05890-1.5857060.7280058.54190HepG2QKI
SYPL1ENSG00000008282.31410.972502221.77780-0.6550015.5877014.50020HepG2NELFE
SYPL1ENSG00000008282.31579.682402069.36210-0.389606.244905.37100HepG2RECQL
SYPL1ENSG00000008282.31748.479801314.962900.411002.184901.58460HepG2SF3A3
SYPL1ENSG00000008282.31384.644801080.371700.357902.782402.07390HepG2SF3B1
SYPL1ENSG00000008282.31443.335201765.38690-0.290604.322103.47380HepG2SLBP
SYPL1ENSG00000008282.31082.007901345.44450-0.314402.928202.26860HepG2SMN1
SYPL1ENSG00000008282.31749.748301202.093500.541502.732701.95660HepG2SNRNP70
SYPL1ENSG00000008282.31274.697601765.01560-0.469508.848207.96060HepG2SRSF9
SYPL1ENSG00000008282.3488.52830855.18890-0.807806.680104.86790HepG2STAU1
SYPL1ENSG00000008282.31505.847702067.48900-0.457309.815308.76510HepG2SUCLG1
SYPL1ENSG00000008282.32303.534101950.113300.240202.482201.94780HepG2TAF15
SYPL1ENSG00000008282.3870.175701258.96640-0.532902.964302.44910HepG2TIAL1
SYPL1ENSG00000008282.3934.639001270.01160-0.442405.435004.69580HepG2TRIM56
SYPL1ENSG00000008282.31594.980401095.117500.542404.900204.07720HepG2U2AF1
SYPL1ENSG00000008282.31354.618301125.892400.266702.779602.18170HepG2UTP3
SYPL1ENSG00000008282.3853.335201284.24070-0.589705.023304.05470HepG2XRN2
SYPL1ENSG00000008282.31072.05440790.230000.439906.327705.38000HepG2ZC3H8
SYPL1ENSG00000008282.31106.785801282.56500-0.212702.250901.74260HepG2ZNF622
SYPL1ENSG00000008282.33199.137301901.509300.7504025.3121023.70690K562AGGF1
SYPL1ENSG00000008282.32644.986102089.483700.340003.247502.16200K562AKAP8
SYPL1ENSG00000008282.32675.092101978.609700.435004.987604.09940K562AKAP8L
SYPL1ENSG00000008282.34300.187203400.919900.338403.109502.49430K562AQR
SYPL1ENSG00000008282.3511.72590685.63950-0.422102.755401.70490K562CCAR1
SYPL1ENSG00000008282.35129.654204234.699500.276503.349802.27570K562CELF1
SYPL1ENSG00000008282.32738.061402129.106500.362805.513504.22380K562DKC1
SYPL1ENSG00000008282.33023.621802122.888900.510106.472305.43970K562EIF2S2
SYPL1ENSG00000008282.3469.59890697.43030-0.570602.736501.73980K562EIF3A
SYPL1ENSG00000008282.31481.430601895.61850-0.355704.463803.46380K562EIF3G
SYPL1ENSG00000008282.31215.184601905.30580-0.648809.005007.52070K562EIF4A3
SYPL1ENSG00000008282.31030.538201715.87050-0.7355010.267207.91990K562EIF4B
SYPL1ENSG00000008282.32661.908101926.777200.466203.278902.49680K562G3BP2
SYPL1ENSG00000008282.31049.815101388.10180-0.403002.076801.38490K562GPKOW
SYPL1ENSG00000008282.31562.297102829.03400-0.8566017.7256015.75350K562GRSF1
SYPL1ENSG00000008282.31606.674402159.78310-0.426805.241703.77770K562HNRNPA1
SYPL1ENSG00000008282.3939.830601479.43940-0.654605.309304.50780K562HNRNPC
SYPL1ENSG00000008282.31032.208901320.87400-0.355802.429501.37330K562HNRNPF
SYPL1ENSG00000008282.33254.394202503.043300.378603.617402.71210K562HSPD1
SYPL1ENSG00000008282.31940.544902511.18810-0.371903.669502.25640K562IGF2BP3
SYPL1ENSG00000008282.32998.879602099.788700.514106.902405.45970K562KIF1C
SYPL1ENSG00000008282.31074.000401499.92010-0.481903.787502.01310K562LIN28B
SYPL1ENSG00000008282.32173.056802589.97070-0.253202.176101.36760K562MATR3
SYPL1ENSG00000008282.33328.504302352.295200.500707.135005.54720K562MBNL1
SYPL1ENSG00000008282.3692.319001712.69360-1.3068048.2661045.67220K562MTPAP
SYPL1ENSG00000008282.32811.198701648.789500.769704.336503.15670K562NAA15
SYPL1ENSG00000008282.34667.927203767.258100.309202.879701.35950K562NOL12
SYPL1ENSG00000008282.31623.325602521.27110-0.6352011.035109.77080K562PTBP1
SYPL1ENSG00000008282.34839.869103757.828300.365003.987903.01250K562PUF60
SYPL1ENSG00000008282.35693.863903996.926000.510409.664807.59840K562PUM1
SYPL1ENSG00000008282.34496.901703916.312500.199302.384001.49160K562PUM2
SYPL1ENSG00000008282.33360.493401962.216100.7761012.7601011.64050K562PUS1
SYPL1ENSG00000008282.31731.194902156.49300-0.316903.461801.43280K562QKI
SYPL1ENSG00000008282.33142.173801911.902000.7167017.8337016.30500K562RBM15
SYPL1ENSG00000008282.31068.044701532.33090-0.520804.699203.34740K562RPS3
SYPL1ENSG00000008282.31688.991701319.957500.355602.352901.46130K562SF3B1
SYPL1ENSG00000008282.31903.503002471.60430-0.376804.313603.43470K562SRSF1
SYPL1ENSG00000008282.31057.065301479.46220-0.485005.338303.78920K562SRSF4
SYPL1ENSG00000008282.31625.325302215.52810-0.446904.070802.49770K562STAU1
SYPL1ENSG00000008282.33031.754901874.015800.693903.029501.51760K562SUPT6H
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SYPL1 is not available on ENCORE database.





6 RBPs can affect the splicing of SYPL1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESYPL1ENSG00000008282.3chr7-1057329931057331151057318521057323851057333941057335830.097000.000000.00036includedK562XRCC6
SESYPL1ENSG00000008282.3chr7-1057330091057331151057319021057323851057333941057335830.061000.000040.01444includedK562PCBP1
SESYPL1ENSG00000008282.3chr7-1057330091057331151057319021057323851057333941057335830.053000.000290.01956includedHepG2PTBP1
SESYPL1ENSG00000008282.3chr7-1057329931057331151057318521057323851057333941057335830.062000.000260.03426includedHepG2TAF15
SESYPL1ENSG00000008282.3chr7-1057329931057331151057318521057323851057333941057335830.082000.000000.00003includedK562HNRNPC
A3SSSYPL1ENSG00000008282.3chr7-1057396031057398161057396031057397281057525851057527770.051000.000000.00000longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SYPL1 is not avaliable on ENCORE database.