SPOP

General Information

Gene Name : SPOP
Gene ID : ENSG00000121067.17
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: SPOP)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	SPOP	ENSG00000121067.17	28.67	28.33	28.50	ENCSR000AEF
HepG2	SPOP	ENSG00000121067.17	34.84	41.00	37.92	ENCSR985KAT
K562	SPOP	ENSG00000121067.17	35.88	36.79	36.34	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for SPOP is not avaliable on ENCORE database.

Proteins bound to RNA

SPOP RNA is bound by 18 proteins.

CanvasJS.com

eCLIP assay for SPOP is not avaliable on ENCORE database.

18 proteins are bound to SPOP RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr17	47755333	47755440	-	5'-UTR,intron-Distal,intron-Proximal	4.21419	12.49859	K562	TARDBP
chr17	47700094	47700221	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.66432	9.47757	K562	YBX3
chr17	47677215	47677283	-	3'-UTR,intron-Distal,intron-Proximal	4.61879	9.20161	K562	UPF1
chr17	47677152	47677215	-	3'-UTR,intron-Distal	4.01616	9.04309	K562	UPF1
chr17	47691714	47691863	-	intron-Distal	4.91850	8.72817	K562	KHSRP
chr17	47676739	47676829	-	3'-UTR,intron-Distal	3.27728	8.47743	K562	UPF1
chr17	47677490	47677567	-	3'-UTR,intron-Distal,intron-Proximal	5.43167	7.60978	K562	UPF1
chr17	47687149	47687292	-	intron-Distal	4.89417	7.55950	K562	MATR3
chr17	47687042	47687126	-	intron-Distal	5.14433	6.95895	K562	PTBP1
chr17	47687117	47687238	-	intron-Distal	5.27057	6.76922	HepG2	PTBP1
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 40 entries

eCLIP assay for SPOP is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for SPOP is not available on ENCORE database.
46 RBPs can affect the levels of SPOP.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for SPOP is not available on ENCORE database.

46 RBPs can affect the gene expression of SPOP :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
SPOP	ENSG00000121067.13	578.35330	913.93480	-0.66010	12.08990	10.89190	HepG2	SMN1
SPOP	ENSG00000121067.13	1248.42410	827.27600	0.59360	10.04620	8.70780	HepG2	PRPF4
SPOP	ENSG00000121067.13	692.45220	1177.90490	-0.76640	9.45330	8.02960	K562	TARDBP
SPOP	ENSG00000121067.13	946.59090	1541.23130	-0.70330	10.38500	7.93990	K562	APOBEC3C
SPOP	ENSG00000121067.13	723.87810	1094.20780	-0.59610	8.64760	7.26310	K562	SF3A3
SPOP	ENSG00000121067.13	846.03110	1285.71990	-0.60380	8.30700	7.17160	HepG2	PUM2
SPOP	ENSG00000121067.13	1801.59540	1345.70130	0.42080	7.48750	6.72380	HepG2	SSB
SPOP	ENSG00000121067.13	717.01220	991.69470	-0.46790	7.11740	6.34490	HepG2	ZNF622
SPOP	ENSG00000121067.13	698.21060	1120.28680	-0.68210	6.65120	5.75580	HepG2	EIF2S1
SPOP	ENSG00000121067.13	1491.11040	979.03880	0.60680	6.63050	5.67190	HepG2	U2AF1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 51 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for SPOP is not available on ENCORE database.

22 RBPs can affect the splicing of SPOP :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	SPOP	ENSG00000121067.13	chr17	-	47745388	47745440			47700094	47700238	47755294	47755387	0.15900	0.00000	0.00027	included	HepG2	G3BP1
SE	SPOP	ENSG00000121067.13	chr17	-	47714120	47714171			47700094	47700238	47755294	47755367	-0.20700	0.00000	0.00045	excluded	K562	PRPF8
SE	SPOP	ENSG00000121067.13	chr17	-	47745388	47745440			47700094	47700238	47755294	47755387	0.16300	0.00000	0.00006	included	HepG2	HNRNPK
SE	SPOP	ENSG00000121067.13	chr17	-	47745388	47745440			47700094	47700238	47755294	47755387	0.25200	0.00000	0.00000	included	HepG2	MATR3
A3SS	SPOP	ENSG00000121067.13	chr17	-	47679226	47679445			47679226	47679369	47684611	47684748	0.08900	0.00000	0.00000	longer	K562	AQR
SE	SPOP	ENSG00000121067.13	chr17	-	47714120	47714171			47700094	47700238	47755294	47755367	0.19100	0.00001	0.00720	included	HepG2	BCLAF1
SE	SPOP	ENSG00000121067.13	chr17	-	47745388	47745440			47700094	47700238	47755294	47755387	0.15700	0.00001	0.00337	included	HepG2	KHSRP
MXE	SPOP	ENSG00000121067.13	chr17	-	47745388	47745440	47753256	47753378	47700094	47700238	47755294	47755472	-0.46000	0.00001	0.00080	2included	HepG2	MATR3
MXE	SPOP	ENSG00000121067.13	chr17	-	47745388	47745440	47753256	47753378	47700094	47700238	47755294	47755472	-0.50600	0.00001	0.00067	2included	HepG2	HNRNPK
SE	SPOP	ENSG00000121067.13	chr17	-	47697982	47698032			47696669	47696747	47699307	47699429	0.12000	0.00002	0.01669	included	HepG2	FAM120A

Showing 1 to 10 of 39 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

SPOP

General Information

Functions

Localization

Domains (AlphaFold: SPOP)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for SPOP is not avaliable on ENCORE database.

18 proteins are bound to SPOP RNA:

eCLIP assay for SPOP is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for SPOP is not available on ENCORE database.

46 RBPs can affect the gene expression of SPOP :

The Knockdown/knockout RNA-Seq assay for SPOP is not available on ENCORE database.

22 RBPs can affect the splicing of SPOP :

The Knockdown/knockout RNA-Seq assay for SPOP is not avaliable on ENCORE database.