SHF

General Information

Gene Name       : SHF
Gene ID             : ENSG00000138606.19
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SHF)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SHFENSG00000138606.190.110.700.40ENCSR000AEF
HepG2SHFENSG00000138606.1920.9515.5418.24ENCSR985KAT
K562SHFENSG00000138606.190.900.640.77ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SHF is not avaliable on ENCORE database.



Proteins bound to RNA
  • SHF RNA is bound by 17 proteins.  







eCLIP assay for SHF is not avaliable on ENCORE database.





17 proteins are bound to SHF RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr154545990145459998-3'-UTR,intron-Distal,intron-Proximal4.514574.96498HepG2GRSF1
chr154545948445459545-3'-UTR,intron-Distal4.636016.45671HepG2UPF1
chr154545982645459915-3'-UTR,intron-Distal,intron-Proximal3.724044.59929HepG2RBM15
chr154545971345459756-3'-UTR,intron-Distal,intron-Proximal4.089453.64119HepG2UPF1
chr154546007345460143-3'-UTR,intron-Distal3.641405.40760HepG2UPF1
chr154545994145460002-3'-UTR,intron-Distal,intron-Proximal4.242545.75355HepG2LIN28B
chr154545954545459675-3'-UTR,intron-Distal6.0721816.32102HepG2UPF1
chr154546371345463837-3'-UTR,intron-Distal,intron-Proximal5.110947.94700HepG2QKI
chr154545955145459640-3'-UTR,intron-Distal5.007377.76785HepG2AKAP1
chr154546006945460138-3'-UTR,intron-Distal4.324484.78280HepG2AKAP1
chr154545978545459933-3'-UTR,intron-Distal,intron-Proximal4.1062116.19422HepG2UPF1
chr154545970345459769-3'-UTR,intron-Distal,intron-Proximal4.197074.51674HepG2AKAP1
chr154547996645480146-CDS,intron-Distal4.320048.44905HepG2UPF1
chr154547031045470371-CDS,intron-Distal,intron-Proximal5.302239.27403HepG2PRPF8
chr154546738445467568-CDS,intron-Distal,intron-Proximal3.455788.34074HepG2PPIG
chr154546737145467470-CDS,intron-Distal,intron-Proximal3.2844310.34449HepG2PRPF8
chr154549260545492649-intron-Distal3.382438.91671K562XRCC6
chr154549264245492646-intron-Distal3.1757513.86353K562LIN28B
chr154549264245492646-intron-Distal3.8113325.10949K562DGCR8
chr154549078045490845-intron-Distal3.322154.40115K562SSB
chr154549077445490791-intron-Distal4.4371980.59149K562ZRANB2
chr154549260545492616-intron-Distal3.4195224.02293K562DGCR8
chr154549264145492646-intron-Distal4.5841227.78835HepG2SND1
chr154549079145490822-intron-Distal3.8822873.77263K562ZRANB2
chr154549259845492654-intron-Distal4.170154.01859K562SSB
chr154549262945492647-intron-Distal3.493037.85449K562SBDS
chr154549087645490892-intron-Distal,intron-Proximal3.931819.73133K562ZRANB2
chr154549261245492642-intron-Distal3.0141815.20861K562LIN28B
chr154549076445490774-intron-Distal7.0079368.48211K562ZRANB2
chr154549260845492645-intron-Distal3.491845.40820K562WRN
chr154549086045490876-intron-Distal,intron-Proximal3.926449.73133K562ZRANB2
chr154549260845492616-intron-Distal4.3624227.44475HepG2SND1
chr154549257045492594-intron-Distal3.705209.31972K562NSUN2
chr154549263845492646-intron-Distal3.082124.08383K562NONO
chr154549262945492641-intron-Distal4.6131528.58281HepG2SND1
chr154549261645492642-intron-Distal3.6423726.19065K562DGCR8
chr154549259445492634-intron-Distal3.1142513.56666K562NSUN2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SHF is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SHF is not available on ENCORE database.

  • 83 RBPs can affect the levels of SHF.  








The Knockdown/knockout RNA-Seq assay for SHF is not available on ENCORE database.





83 RBPs can affect the gene expression of SHF :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SHFENSG00000138606.15124.87480260.19280-1.059107.124905.49280HepG2AATF
SHFENSG00000138606.15180.36490359.27320-0.9942010.937209.89600HepG2ACO1
SHFENSG00000138606.15169.47160887.15220-2.3881032.3076030.74660HepG2AKAP1
SHFENSG00000138606.15465.77600733.99370-0.656105.449904.36490HepG2ASCC1
SHFENSG00000138606.15165.16240259.77410-0.653402.414801.69120HepG2CALR
SHFENSG00000138606.15900.08300697.360800.368102.268101.56320HepG2CIRBP
SHFENSG00000138606.15114.44180240.83590-1.073405.229804.17370HepG2CNOT7
SHFENSG00000138606.15255.35630161.474100.661102.903202.20130HepG2CPSF6
SHFENSG00000138606.15162.85020266.41170-0.710103.234101.72520HepG2CSTF2T
SHFENSG00000138606.15416.01070849.71680-1.0304011.5138010.31710HepG2DDX3X
SHFENSG00000138606.15258.20300730.17850-1.4997017.5099016.13460HepG2DDX6
SHFENSG00000138606.15353.66480251.997600.488902.723601.74550HepG2DHX30
SHFENSG00000138606.15510.74120343.728200.571205.191504.31630HepG2DKC1
SHFENSG00000138606.15408.20850261.272200.643703.841603.02410HepG2DNAJC21
SHFENSG00000138606.15209.68540355.03760-0.759704.557803.39890HepG2EEF2
SHFENSG00000138606.15314.72170701.68600-1.1567013.2213011.99280HepG2EIF2S1
SHFENSG00000138606.15150.61260288.20170-0.936206.323104.99490HepG2EIF3D
SHFENSG00000138606.15340.41590755.11920-1.1494010.559809.25900HepG2EIF4B
SHFENSG00000138606.15464.16730626.55300-0.432803.822403.13600HepG2ETF1
SHFENSG00000138606.15178.56630426.70720-1.2568010.164208.81350HepG2FIP1L1
SHFENSG00000138606.1576.29110161.76760-1.084302.883701.84600HepG2FTO
SHFENSG00000138606.15429.13370576.01540-0.424702.870002.06920HepG2FUBP3
SHFENSG00000138606.15211.23570324.26140-0.618302.550501.47760HepG2FUS
SHFENSG00000138606.15525.46900782.63820-0.574704.495603.62820HepG2FXR1
SHFENSG00000138606.15296.85610725.81740-1.2898015.6160014.09580HepG2G3BP1
SHFENSG00000138606.15438.99730236.121300.894609.957108.70280HepG2HNRNPF
SHFENSG00000138606.15350.93210735.40940-1.067409.815408.56790HepG2HNRNPK
SHFENSG00000138606.15173.13680294.38790-0.765805.048203.80390HepG2HNRNPM
SHFENSG00000138606.15570.27190232.509901.2943015.9356014.35440HepG2IGF2BP1
SHFENSG00000138606.15567.76460737.70840-0.377802.208001.59640HepG2IGF2BP2
SHFENSG00000138606.15233.32050692.58590-1.569708.147406.53410HepG2IGF2BP3
SHFENSG00000138606.15498.73260742.13790-0.573403.505702.35960HepG2KHSRP
SHFENSG00000138606.15505.23400328.423400.621306.928805.36390HepG2KIF1C
SHFENSG00000138606.15331.61090490.01150-0.563302.930002.07470HepG2LARP4
SHFENSG00000138606.15191.73770286.02870-0.577003.153101.94160HepG2LARP7
SHFENSG00000138606.15487.95200782.91310-0.682103.699102.94070HepG2MAGOH
SHFENSG00000138606.15314.39130787.23490-1.3242014.5858013.21950HepG2MATR3
SHFENSG00000138606.15182.71120301.62220-0.723202.515201.50910HepG2METAP2
SHFENSG00000138606.15173.04930345.31430-0.996708.050706.73720HepG2MSI2
SHFENSG00000138606.15278.06600178.181400.642002.478801.56490HepG2MTPAP
SHFENSG00000138606.15269.35040805.72980-1.5808019.4590017.87840HepG2NCBP2
SHFENSG00000138606.15344.13800457.83530-0.411802.474901.75620HepG2NOL12
SHFENSG00000138606.15255.62570154.887900.722703.431102.59750HepG2NSUN2
SHFENSG00000138606.15272.29220717.33060-1.3975015.9010014.22790HepG2PABPC4
SHFENSG00000138606.15198.66740288.49650-0.538203.186802.28450HepG2PARN
SHFENSG00000138606.15412.74630742.09510-0.8463013.9021012.70830HepG2PCBP1
SHFENSG00000138606.15408.41080259.961100.651605.617604.60000HepG2PPIL4
SHFENSG00000138606.15115.36950200.83490-0.799703.777902.85200HepG2PRPF8
SHFENSG00000138606.15263.25370755.07800-1.5202034.0554032.57040HepG2PTBP1
SHFENSG00000138606.15672.26230437.066100.621106.032205.19650HepG2PUF60
SHFENSG00000138606.15240.12920463.99100-0.9503012.2432011.18290HepG2PUM1
SHFENSG00000138606.15350.78160817.83520-1.2212022.7965021.25610HepG2QKI
SHFENSG00000138606.1565.68860296.06200-2.1722013.5069012.06070HepG2RAVER1
SHFENSG00000138606.15421.03670523.67900-0.314701.930901.47760HepG2RBM22
SHFENSG00000138606.15349.07900742.21270-1.0883016.2738014.71750HepG2RBM25
SHFENSG00000138606.15559.11340840.35550-0.587907.592006.77470HepG2NELFE
SHFENSG00000138606.15585.60350782.62940-0.418404.238103.49660HepG2RECQL
SHFENSG00000138606.15401.63280254.392600.658704.208903.39350HepG2RPLP0
SHFENSG00000138606.15168.51650280.44360-0.734804.490803.72790HepG2RPS19
SHFENSG00000138606.15199.76560318.08690-0.671103.937402.99040HepG2RPS2
SHFENSG00000138606.15219.85210324.71180-0.562603.093101.95230HepG2RPS5
SHFENSG00000138606.1595.40880198.65680-1.058105.421104.35470HepG2RRP9
SHFENSG00000138606.15161.20900281.45210-0.804004.907703.66650HepG2SERBP1
SHFENSG00000138606.15315.53310786.19010-1.3171028.1395026.59220HepG2SF3B4
SHFENSG00000138606.15510.05650419.131700.283202.011301.39580HepG2SLBP
SHFENSG00000138606.15200.87270302.68920-0.591604.140503.38100HepG2SMN1
SHFENSG00000138606.15135.73100302.52870-1.156304.859303.55590HepG2SMNDC1
SHFENSG00000138606.15108.47570192.35150-0.826402.971502.16020HepG2SNRNP70
SHFENSG00000138606.15362.99950591.47010-0.704308.637307.88680HepG2SRFBP1
SHFENSG00000138606.15347.85980820.58920-1.2382026.3703025.23540HepG2SRSF1
SHFENSG00000138606.15413.65500231.988800.834308.512707.40640HepG2SRSF7
SHFENSG00000138606.15357.97650667.57320-0.8991014.8994013.80130HepG2SRSF9
SHFENSG00000138606.15618.07240513.525500.267201.810901.37440HepG2SSB
SHFENSG00000138606.15383.32380490.78760-0.356502.277701.70300HepG2SUCLG1
SHFENSG00000138606.15167.02900259.27540-0.634402.845002.15960HepG2SUPV3L1
SHFENSG00000138606.15293.55170737.51360-1.3291026.0525024.56480HepG2TAF15
SHFENSG00000138606.15394.74790677.74240-0.779809.513007.98020HepG2TIA1
SHFENSG00000138606.15231.09590365.00060-0.659403.972403.22580HepG2U2AF1
SHFENSG00000138606.15311.46430452.04050-0.537402.385801.61230HepG2UBE2L3
SHFENSG00000138606.1572.51310153.14090-1.078505.436304.36500HepG2UCHL5
SHFENSG00000138606.15151.70600291.34590-0.941504.407702.80890HepG2XRCC5
SHFENSG00000138606.15461.16050255.229100.853405.400304.39770HepG2XRN2
SHFENSG00000138606.1528.186508.439001.739802.215501.50100K562HSPD1
SHFENSG00000138606.1531.961709.944801.684202.225901.49750K562RPS19
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SHF is not available on ENCORE database.





8 RBPs can affect the splicing of SHF :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESHFENSG00000138606.15chr15-454640804546420045459910454603314546741645467623-0.321000.000010.00095excludedHepG2RBM22
SESHFENSG00000138606.15chr15-4546408045464200454599104546033145467416454676230.260000.004820.09314includedHepG2HNRNPK
SESHFENSG00000138606.15chr15-4546577345465914454643444546451645467416454676230.149000.007360.07179includedHepG2U2AF2
SESHFENSG00000138606.15chr15-4546577345465914454643444546451645467416454676230.162000.000000.00024includedHepG2PTBP1
SESHFENSG00000138606.15chr15-454643444546451645464080454642004546741645467623-0.215000.001820.06534excludedHepG2MATR3
SESHFENSG00000138606.15chr15-454643444546451645464080454642004546741645467623-0.440000.000000.00000excludedHepG2SRSF1
SESHFENSG00000138606.15chr15-454640804546420045459411454603314546741645467623-0.274000.000150.02462excludedHepG2SSB
SESHFENSG00000138606.15chr15-454643444546451645464080454642004546741645467623-0.306000.000400.01892excludedHepG2HNRNPC
A3SSSHFENSG00000138606.15chr15-4546408045464246454640804546420045464344454645160.314000.000120.01495longerHepG2RBM22
A5SSSHFENSG00000138606.15chr15-4546434445464516454643464546451645464080454642000.341000.000440.07915longerHepG2PTBP1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SHF is not avaliable on ENCORE database.