PRKACA

General Information

Gene Name       : PRKACA
Gene ID             : ENSG00000072062.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PRKACA)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PRKACAENSG00000072062.1327.9638.6533.30ENCSR000AEF
HepG2PRKACAENSG00000072062.1341.3038.8740.08ENCSR985KAT
K562PRKACAENSG00000072062.1336.5539.9838.27ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PRKACA is not avaliable on ENCORE database.



Proteins bound to RNA
  • PRKACA RNA is bound by 20 proteins.  







eCLIP assay for PRKACA is not avaliable on ENCORE database.





20 proteins are bound to PRKACA RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr191420380814203869-3'-UTR,intron-Distal,intron-Proximal3.4135510.57049K562TIA1
chr191420363714203705-3'-UTR,CDS,intron-Distal3.472228.05942HepG2UPF1
chr191420362714203727-3'-UTR,CDS,intron-Distal4.941377.25683HepG2PCBP1
chr191420284314202902-3'-UTR,intron-Distal,intron-Proximal3.224948.84790K562FAM120A
chr191420379014203812-3'-UTR,intron-Distal,intron-Proximal4.8740632.20136K562FAM120A
chr191420266214202725-3'-UTR,intron-Distal4.0367315.28416K562UPF1
chr191420291814202993-3'-UTR,intron-Distal3.680687.34603K562HNRNPK
chr191420320114203270-3'-UTR,intron-Distal3.8278214.48199K562UPF1
chr191420323214203276-3'-UTR,intron-Distal3.5754819.92705K562FAM120A
chr191420358514203631-3'-UTR,CDS,intron-Distal4.098873.08342HepG2AKAP1
chr191420363014203705-3'-UTR,CDS,intron-Distal5.0797325.67434HepG2DDX59
chr191420378014203808-3'-UTR,intron-Distal,intron-Proximal3.522777.70712K562TIA1
chr191420290214202974-3'-UTR,intron-Distal3.8420535.61762K562FAM120A
chr191420360114203621-3'-UTR,CDS,intron-Distal5.089166.42388HepG2DDX59
chr191420356514203630-3'-UTR,CDS,intron-Distal3.246947.81904K562ILF3
chr191420362914203693-3'-UTR,CDS,intron-Distal4.6202518.35369K562UPF1
chr191420256714202662-3'-UTR,intron-Distal6.3045337.35228K562UPF1
chr191420262414202684-3'-UTR,intron-Distal4.809247.31085HepG2PCBP2
chr191420363214203688-3'-UTR,CDS,intron-Distal3.132015.88353HepG2CSTF2T
chr191420378714203811-3'-UTR,intron-Distal,intron-Proximal5.101318.53428HepG2FAM120A
chr191420355914203624-3'-UTR,CDS,intron-Distal4.0762529.63639K562FAM120A
chr191420364114203685-3'-UTR,CDS,intron-Distal4.773075.48383HepG2LARP4
chr191420381214203857-3'-UTR,intron-Distal,intron-Proximal4.6436130.57897K562FAM120A
chr191420292314202982-3'-UTR,intron-Distal6.002278.60492HepG2PCBP2
chr191420328614203349-3'-UTR,intron-Distal6.2348939.58299HepG2PCBP2
chr191420328914203357-3'-UTR,intron-Distal4.160296.94777HepG2FAM120A
chr191420260014202715-3'-UTR,intron-Distal5.9218512.58146HepG2UPF1
chr191420362414203688-3'-UTR,CDS,intron-Distal3.326579.96039K562FAM120A
chr191420257514202663-3'-UTR,intron-Distal3.098943.99400K562DDX6
chr191420298214203014-3'-UTR,intron-Distal4.455226.92189HepG2PCBP2
chr191420378314203879-3'-UTR,intron-Distal,intron-Proximal5.123226.42882HepG2TIAL1
chr191420364414203688-3'-UTR,CDS,intron-Distal3.094934.26844K562DDX55
chr191420291214202975-3'-UTR,intron-Distal3.252345.75977HepG2UPF1
chr191420376914203807-3'-UTR,intron-Distal,intron-Proximal4.9464927.39129K562UPF1
chr191420380714203857-3'-UTR,intron-Distal,intron-Proximal4.4073242.67280K562UPF1
chr191420317714203232-3'-UTR,intron-Distal4.5139823.91865K562FAM120A
chr191420292114202984-3'-UTR,intron-Distal4.554323.87385HepG2AKAP1
chr191420286014202951-3'-UTR,intron-Distal3.7366132.55298K562UPF1
chr191420256814202677-3'-UTR,intron-Distal3.9046832.74408K562FAM120A
chr191420295114202987-3'-UTR,intron-Distal3.8454824.81907K562UPF1
chr191420307714203112-3'-UTR,intron-Distal4.6186512.82485K562FAM120A
chr191420381114203854-3'-UTR,intron-Distal,intron-Proximal3.725184.56358HepG2FAM120A
chr191420362914203689-3'-UTR,CDS,intron-Distal3.496685.41342HepG2FAM120A
chr191420268614202704-3'-UTR,intron-Distal4.076543.94601K562PCBP1
chr191420377014203790-3'-UTR,intron-Distal,intron-Proximal4.8435633.74323K562FAM120A
chr191420357914203626-3'-UTR,CDS,intron-Distal3.636015.64093HepG2UPF1
chr191420375914203854-3'-UTR,intron-Distal,intron-Proximal3.5708612.50254K562PABPC4
chr191420363614203713-3'-UTR,CDS,intron-Distal3.719358.53153K562HNRNPK
chr191420291214202976-3'-UTR,intron-Distal3.008097.03937K562CSTF2T
chr191420378014203812-3'-UTR,intron-Distal,intron-Proximal3.359443.25356HepG2DDX59
chr191420260514202667-3'-UTR,intron-Distal4.210073.08342HepG2AKAP1
chr191421815714218214-3'-UTR,CDS,intron-Distal,intron-Proximal3.957764.04622HepG2GRWD1
chr191420365814203691-3'-UTR,intron-Distal3.084615.24441K562ILF3
chr191420357314203629-3'-UTR,CDS,intron-Distal4.1112817.07639K562UPF1
chr191420258414202664-3'-UTR,intron-Distal4.043174.10564HepG2CSTF2T
chr191420377114203802-3'-UTR,intron-Distal,intron-Proximal4.390105.31599HepG2AKAP1
chr191420377414203862-3'-UTR,intron-Distal,intron-Proximal3.710094.53578K562AKAP8L
chr191420377314203858-3'-UTR,intron-Distal,intron-Proximal3.6121310.01098HepG2LARP4
chr191420328614203337-3'-UTR,intron-Distal3.026403.29363HepG2HNRNPK
chr191420376714203859-3'-UTR,intron-Distal,intron-Proximal3.495726.36921K562DDX6
chr191420377214203802-3'-UTR,intron-Distal,intron-Proximal4.346596.58258HepG2PCBP2
chr191420376214203857-3'-UTR,intron-Distal,intron-Proximal5.9902417.82175HepG2UPF1
chr191420330314203352-3'-UTR,intron-Distal3.077875.20034K562PCBP1
chr191420319614203258-3'-UTR,intron-Distal4.776495.14974HepG2UPF1
chr191420363914203733-3'-UTR,CDS,intron-Distal4.4114620.46838K562PCBP1
chr191420380214203857-3'-UTR,intron-Distal,intron-Proximal4.090376.42285HepG2AKAP1
chr191420363014203658-3'-UTR,CDS,intron-Distal3.578827.41257K562ILF3
chr191420258714202659-3'-UTR,intron-Distal3.540593.85040HepG2IGF2BP1
chr191420362814203732-3'-UTR,CDS,intron-Distal4.9457314.05385HepG2HNRNPK
chr191420376614203787-3'-UTR,intron-Distal,intron-Proximal5.677677.83501HepG2FAM120A
chr191420362614203721-3'-UTR,CDS,intron-Distal5.7361652.95117HepG2PCBP2
chr191420378214203862-3'-UTR,intron-Distal,intron-Proximal3.554056.88236K562DDX55
chr191422839414228547-5'-UTR,intron-Distal,intron-Proximal4.0518110.68796HepG2DDX3X
chr191422833014228388-5'-UTR,CDS,intron-Distal3.923984.17587HepG2DDX3X
chr191421158214211717-CDS,intron-Distal,intron-Proximal4.881829.43475HepG2PRPF8
chr191422789714227997-intron-Distal3.089164.52901HepG2DDX59
chr191422773414227823-intron-Distal3.803036.33671HepG2HNRNPK
chr191422807814228125-intron-Distal4.477963.97933HepG2DDX59
chr191422774114227800-intron-Distal3.999505.10672HepG2DDX59
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PRKACA is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PRKACA is not available on ENCORE database.

  • 81 RBPs can affect the levels of PRKACA.  








The Knockdown/knockout RNA-Seq assay for PRKACA is not available on ENCORE database.





81 RBPs can affect the gene expression of PRKACA :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PRKACAENSG00000072062.91434.877501890.01960-0.397502.673002.15000HepG2AKAP1
PRKACAENSG00000072062.91232.732001563.74800-0.343102.382301.64980HepG2ASCC1
PRKACAENSG00000072062.92337.853301846.947200.339903.058102.43220HepG2BOP1
PRKACAENSG00000072062.91201.816601485.69560-0.305902.031301.36240HepG2CIRBP
PRKACAENSG00000072062.9562.852801810.31440-1.6854037.9766035.94370HepG2DDX3X
PRKACAENSG00000072062.91701.452801225.486400.473307.721906.70390HepG2DNAJC2
PRKACAENSG00000072062.91018.422901494.93960-0.553805.113504.32220HepG2EIF2S1
PRKACAENSG00000072062.9785.38380983.62050-0.324702.438901.42490HepG2EIF3G
PRKACAENSG00000072062.9911.614601608.72750-0.819407.387006.29390HepG2EIF4B
PRKACAENSG00000072062.91054.978701906.62150-0.8538023.8598022.39290HepG2ETF1
PRKACAENSG00000072062.91016.487101285.15780-0.338402.879302.02850HepG2EWSR1
PRKACAENSG00000072062.91704.834202508.52050-0.557205.248004.21580HepG2FIP1L1
PRKACAENSG00000072062.91229.31580982.289700.323502.117601.33860HepG2GEMIN5
PRKACAENSG00000072062.91473.407901255.606000.230702.331601.42910HepG2HDGF
PRKACAENSG00000072062.91897.749501388.409500.450804.720003.83080HepG2HNRNPC
PRKACAENSG00000072062.92263.922901977.402300.195101.904401.30200HepG2HNRNPF
PRKACAENSG00000072062.9909.455501566.56790-0.7845010.829709.52880HepG2HNRNPK
PRKACAENSG00000072062.91314.574601510.20400-0.200102.223401.60940HepG2HNRNPL
PRKACAENSG00000072062.91359.096101730.46260-0.348503.600902.52690HepG2HNRNPM
PRKACAENSG00000072062.91601.732501379.229000.215702.189801.64370HepG2HNRNPU
PRKACAENSG00000072062.92342.028701947.168900.266302.323401.65830HepG2IGF2BP1
PRKACAENSG00000072062.91197.040501581.07970-0.401402.341101.43080HepG2KHSRP
PRKACAENSG00000072062.93398.952302264.963600.585505.022403.89050HepG2LARP4
PRKACAENSG00000072062.9792.651901667.88220-1.0733015.1047013.62770HepG2MAGOH
PRKACAENSG00000072062.91383.923301716.53950-0.310701.973401.43390HepG2NCBP2
PRKACAENSG00000072062.91307.265401643.90240-0.330603.680602.79930HepG2NOL12
PRKACAENSG00000072062.9887.925501700.13670-0.9371027.8538026.26890HepG2PCBP1
PRKACAENSG00000072062.9896.637101259.20770-0.489902.752101.71430HepG2PCBP2
PRKACAENSG00000072062.91398.807101729.94470-0.306503.980803.35100HepG2PTBP1
PRKACAENSG00000072062.9842.521901664.55510-0.9824022.5978020.80110HepG2PUM2
PRKACAENSG00000072062.9729.980001214.89910-0.734904.328503.45660HepG2RAVER1
PRKACAENSG00000072062.91008.819301593.59010-0.6596011.8949010.97550HepG2RBM22
PRKACAENSG00000072062.9997.962001700.39680-0.7688013.1352011.72920HepG2RBM25
PRKACAENSG00000072062.9946.763501239.64720-0.388902.923801.90240HepG2RBM27
PRKACAENSG00000072062.91306.531601925.26900-0.5593011.2235010.27320HepG2NELFE
PRKACAENSG00000072062.91290.577401793.11440-0.474508.393607.40740HepG2RECQL
PRKACAENSG00000072062.91794.532201193.886000.587803.859102.74490HepG2RPS10
PRKACAENSG00000072062.91815.747801073.628500.7580010.315709.21820HepG2RPS19
PRKACAENSG00000072062.9598.11090910.84210-0.606804.867103.85740HepG2RRP9
PRKACAENSG00000072062.9841.006301228.25530-0.546409.819408.72260HepG2SAFB2
PRKACAENSG00000072062.91597.342501077.396500.568005.899704.54210HepG2SERBP1
PRKACAENSG00000072062.91408.671501815.64790-0.366103.068002.32570HepG2SF3B1
PRKACAENSG00000072062.91141.746201801.11010-0.6576014.7554013.55480HepG2SF3B4
PRKACAENSG00000072062.91147.570701432.33770-0.319804.678103.87830HepG2SMN1
PRKACAENSG00000072062.91516.058902020.21930-0.414202.154601.46850HepG2SNRNP70
PRKACAENSG00000072062.91316.745001799.91420-0.451008.268007.52920HepG2SRFBP1
PRKACAENSG00000072062.91920.071501549.317200.309404.032903.30290HepG2SRSF5
PRKACAENSG00000072062.91016.090001529.44510-0.5900012.4778011.45430HepG2SRSF9
PRKACAENSG00000072062.91046.159202317.04760-1.1472018.4586015.64460HepG2SSRP1
PRKACAENSG00000072062.92249.267701787.812700.331202.771602.04660HepG2TARDBP
PRKACAENSG00000072062.9437.02520796.53010-0.866008.982507.39540HepG2TFIP11
PRKACAENSG00000072062.91267.392401552.68370-0.292902.574901.76600HepG2TIA1
PRKACAENSG00000072062.91964.443101340.120200.551703.273102.73620HepG2TIAL1
PRKACAENSG00000072062.91279.049102145.59680-0.7463010.923709.65340HepG2U2AF1
PRKACAENSG00000072062.9465.14040702.00570-0.593804.901503.88420HepG2UCHL5
PRKACAENSG00000072062.92515.197001884.391900.416508.631807.51210HepG2UPF1
PRKACAENSG00000072062.91031.257301819.30100-0.8190022.7886021.31650HepG2UTP3
PRKACAENSG00000072062.93284.279901889.236200.797707.213706.21340HepG2ZC3H8
PRKACAENSG00000072062.92549.925502072.465500.299005.795305.07970HepG2ZNF622
PRKACAENSG00000072062.92192.163702640.22680-0.268302.251301.37650K562AKAP8
PRKACAENSG00000072062.91408.178801738.55310-0.304102.229801.69390K562AQR
PRKACAENSG00000072062.92181.043902623.29290-0.266403.164602.18370K562ATP5C1
PRKACAENSG00000072062.92057.284702374.12420-0.206702.358401.34290K562CPEB4
PRKACAENSG00000072062.9765.05360935.30480-0.289902.647801.35730K562DDX27
PRKACAENSG00000072062.92115.848802456.73940-0.215502.616401.98030K562DDX47
PRKACAENSG00000072062.91948.240402690.70660-0.465808.726307.00540K562DKC1
PRKACAENSG00000072062.9854.972201151.31500-0.429303.081301.87870K562FKBP4
PRKACAENSG00000072062.9402.20810734.81810-0.869404.654403.68480K562G3BP2
PRKACAENSG00000072062.91980.047201610.597100.297802.452801.70320K562GPKOW
PRKACAENSG00000072062.91779.339701326.705600.423404.692603.93570K562HNRNPC
PRKACAENSG00000072062.91582.583501184.605500.417804.317502.85370K562HNRNPF
PRKACAENSG00000072062.9668.174901104.05860-0.724507.732405.59040K562HNRNPK
PRKACAENSG00000072062.91626.030001284.313900.340302.973001.52600K562LARP7
PRKACAENSG00000072062.91795.471701345.274800.416403.492901.79720K562LIN28B
PRKACAENSG00000072062.9698.229801161.91460-0.7347010.233408.55460K562MAGOH
PRKACAENSG00000072062.92443.117402972.61180-0.283003.070602.10380K562MBNL1
PRKACAENSG00000072062.91187.74050959.725200.307402.631501.43140K562NCBP2
PRKACAENSG00000072062.92365.200501491.525200.665103.011401.96940K562PABPN1
PRKACAENSG00000072062.9638.390401033.72250-0.695308.131206.41980K562PCBP2
PRKACAENSG00000072062.92404.262401959.901300.294702.283001.53830K562PPIG
PRKACAENSG00000072062.9702.82500946.81930-0.429902.956502.18300K562PRPF8
PRKACAENSG00000072062.91578.561601189.490400.408203.755602.67950K562PSIP1
PRKACAENSG00000072062.91571.835001085.062500.534607.075505.48680K562RCC2
PRKACAENSG00000072062.91665.168101187.567600.487604.468203.15820K562RPS3
PRKACAENSG00000072062.91571.416701028.630300.611207.590305.64480K562SRFBP1
PRKACAENSG00000072062.91487.863501146.325100.376103.448802.25540K562SRSF4
PRKACAENSG00000072062.91774.356302264.96700-0.352202.931301.52730K562SSRP1
PRKACAENSG00000072062.91713.410601144.114300.582505.951404.52630K562TIAL1
PRKACAENSG00000072062.91782.917401215.257700.552904.815103.48430K562TRIM56
PRKACAENSG00000072062.9482.85150711.48030-0.559202.372401.37120K562U2AF1
PRKACAENSG00000072062.9416.54420735.06510-0.819404.559403.53380K562U2AF2
PRKACAENSG00000072062.92321.155102976.17010-0.358602.963201.71630K562UTP3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PRKACA is not available on ENCORE database.





1 RBPs can affect the splicing of PRKACA :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPRKACAENSG00000072062.9chr19-142044391420460414203861142040491420817214208295-0.102000.000270.04488excludedK562HNRNPM

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PRKACA is not avaliable on ENCORE database.