POLE4

General Information

Gene Name       : POLE4
Gene ID             : ENSG00000115350.11
Essential Gene : No

Functions

Localization

Domains (AlphaFold: POLE4)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878POLE4ENSG00000115350.1127.6926.1926.94ENCSR000AEF
HepG2POLE4ENSG00000115350.1180.8763.6372.25ENCSR985KAT
K562POLE4ENSG00000115350.1122.3517.9320.14ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for POLE4 is not avaliable on ENCORE database.



Proteins bound to RNA
  • POLE4 RNA is bound by 15 proteins.  







eCLIP assay for POLE4 is not avaliable on ENCORE database.





15 proteins are bound to POLE4 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr27519653875196621+3'-UTR,CDS3.406558.01683HepG2LARP4
chr27519674975196786+3'-UTR3.906783.46958K562YBX3
chr27519673675196793+3'-UTR3.405534.22050HepG2LARP4
chr27519685775196940+3'-UTR,polyA_site4.497335.45333HepG2CSTF2
chr27519665375196743+3'-UTR4.423194.08466HepG2IGF2BP1
chr27519672475196795+3'-UTR3.408243.99870K562IGF2BP1
chr27519669975196736+3'-UTR4.271963.15159HepG2LARP4
chr27519653575196609+3'-UTR,CDS,intron-Proximal3.448103.68457K562LIN28B
chr27518578975185855+5'-UTR,CDS4.060496.67587HepG2DDX3X
chr27518589675185959+CDS4.054216.48236HepG2DDX3X
chr27518596675186020+CDS,intron-Proximal3.952013.56019HepG2GRWD1
chr27518646775186524+CDS,intron-Proximal4.152894.31428K562YBX3
chr27518654275186602+CDS,intron-Proximal4.458763.93614HepG2AQR
chr27518585575185896+CDS4.766236.83552HepG2DDX3X
chr27518646575186554+CDS,intron-Proximal3.337605.54854HepG2GRWD1
chr27518653775186608+CDS,intron-Proximal3.791219.70941HepG2PRPF8
chr27518723675187269+CDS3.177223.01032HepG2LARP4
chr27518589475185964+CDS3.326434.32211K562DDX3X
chr27519578275195843+intron-Distal3.937056.21102HepG2MATR3
chr27519555175195678+intron-Distal5.104976.95924HepG2HNRNPM
chr27519470475194737+intron-Distal3.059523.23296HepG2SUGP2
chr27518668075186771+intron-Distal,intron-Proximal3.757093.05559HepG2DGCR8
chr27519120375191318+intron-Distal3.446833.84025HepG2SUGP2
chr27519629475196377+intron-Distal3.278595.31346HepG2QKI
chr27518767575187744+intron-Distal4.069723.48768HepG2KHSRP
chr27519555675195611+intron-Distal5.412958.67089HepG2SUGP2
chr27519577275195855+intron-Distal3.7519811.69397HepG2SUGP2
chr27519126375191349+intron-Distal3.139244.23155HepG2MATR3
chr27519612575196160+intron-Distal3.648213.34056HepG2MATR3
chr27519305575193142+intron-Distal3.921353.26999K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for POLE4 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for POLE4 is not available on ENCORE database.

  • 72 RBPs can affect the levels of POLE4.  








The Knockdown/knockout RNA-Seq assay for POLE4 is not available on ENCORE database.





72 RBPs can affect the gene expression of POLE4 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
POLE4ENSG00000115350.7560.68020421.908100.410103.567502.89270HepG2ACO1
POLE4ENSG00000115350.71121.99920699.393500.681805.700704.96920HepG2AKAP1
POLE4ENSG00000115350.7574.47380423.862400.438503.853002.96120HepG2AKAP8L
POLE4ENSG00000115350.7816.30680578.690100.496203.522202.63780HepG2ASCC1
POLE4ENSG00000115350.7183.82800262.04760-0.511502.264201.71720HepG2BOP1
POLE4ENSG00000115350.7613.70960326.852400.908805.934104.81170HepG2CNOT7
POLE4ENSG00000115350.7180.99950330.27380-0.867706.420205.03510HepG2DDX24
POLE4ENSG00000115350.7262.10410412.99460-0.656003.021601.67700HepG2DDX27
POLE4ENSG00000115350.7202.25700334.38850-0.725304.223202.51750HepG2DDX28
POLE4ENSG00000115350.7999.78430669.967700.577404.757403.95460HepG2DDX3X
POLE4ENSG00000115350.7297.58890441.36860-0.568702.772601.99880HepG2DDX55
POLE4ENSG00000115350.7887.48410575.512300.624804.724503.93690HepG2DDX6
POLE4ENSG00000115350.7253.38480403.64300-0.671805.673804.76770HepG2DKC1
POLE4ENSG00000115350.7393.92870257.304100.614403.020302.29090HepG2DNAJC21
POLE4ENSG00000115350.7387.07560611.41660-0.659504.629003.80420HepG2EIF4A3
POLE4ENSG00000115350.7674.48950809.15460-0.262602.105801.56650HepG2ETF1
POLE4ENSG00000115350.7298.66680191.109800.644003.973902.54610HepG2FAM120A
POLE4ENSG00000115350.7437.77920607.52060-0.472702.865101.95490HepG2G3BP2
POLE4ENSG00000115350.7125.68610190.30910-0.598502.108501.33110HepG2GEMIN5
POLE4ENSG00000115350.7122.03450272.69570-1.160007.349306.33600HepG2GPKOW
POLE4ENSG00000115350.7518.80760402.781100.365102.762401.78750HepG2HDGF
POLE4ENSG00000115350.7150.68130260.23940-0.788304.051003.30410HepG2HNRNPLL
POLE4ENSG00000115350.7214.75060344.37920-0.681304.846703.91410HepG2IGF2BP1
POLE4ENSG00000115350.7337.15750617.10360-0.872107.844106.75290HepG2MAGOH
POLE4ENSG00000115350.71108.61590620.558300.837008.518507.46190HepG2MATR3
POLE4ENSG00000115350.7135.07340230.75900-0.772603.450302.61400HepG2NSUN2
POLE4ENSG00000115350.7323.22880531.31050-0.717008.326707.36690HepG2PCBP1
POLE4ENSG00000115350.7171.64840305.77590-0.833004.392503.10230HepG2PCBP2
POLE4ENSG00000115350.7412.09440589.65890-0.516903.691403.01410HepG2PUF60
POLE4ENSG00000115350.7456.05660295.029700.628302.608001.92320HepG2RAVER1
POLE4ENSG00000115350.71116.36450676.307400.7230012.1775011.24920HepG2RBM22
POLE4ENSG00000115350.7371.35290601.65910-0.696207.941607.10920HepG2NELFE
POLE4ENSG00000115350.7349.77400560.31960-0.679805.216104.40420HepG2RECQL
POLE4ENSG00000115350.7145.18620208.02520-0.518902.144001.59630HepG2RPS19
POLE4ENSG00000115350.7195.74850328.16730-0.745403.924302.97270HepG2RPS3A
POLE4ENSG00000115350.7199.30700503.12680-1.335904.476702.66010HepG2SF1
POLE4ENSG00000115350.7424.77610562.88580-0.406103.277802.64050HepG2SF3B4
POLE4ENSG00000115350.7234.67590449.35890-0.937202.718301.42320HepG2SNRNP200
POLE4ENSG00000115350.7461.99550286.604900.688703.347302.48290HepG2SNRNP70
POLE4ENSG00000115350.7984.84760763.871200.366504.004103.43390HepG2SRFBP1
POLE4ENSG00000115350.7254.69480343.59990-0.432002.656801.97490HepG2SRSF7
POLE4ENSG00000115350.7351.88700477.95180-0.441803.178902.59580HepG2SRSF9
POLE4ENSG00000115350.7423.88770663.23310-0.645808.094407.30490HepG2SSB
POLE4ENSG00000115350.7318.00820528.01710-0.731503.872603.22780HepG2TAF15
POLE4ENSG00000115350.7180.54410253.67840-0.490602.016901.38630HepG2TARDBP
POLE4ENSG00000115350.7461.77720309.608700.576705.413004.48730HepG2UPF1
POLE4ENSG00000115350.7608.87860298.913701.0263010.811309.75270HepG2UTP3
POLE4ENSG00000115350.7183.70970290.20680-0.659702.568301.35930HepG2XRCC5
POLE4ENSG00000115350.7157.84630242.48770-0.619402.973702.28170HepG2ZC3H8
POLE4ENSG00000115350.7490.16150340.509100.525505.136304.44880HepG2ZNF622
POLE4ENSG00000115350.7312.84240150.707001.053609.565608.59120K562AGGF1
POLE4ENSG00000115350.7253.96400165.607300.616802.514001.58570K562AKAP8
POLE4ENSG00000115350.7355.99100156.818201.1826010.448009.07150K562AKAP8L
POLE4ENSG00000115350.7498.17500371.052200.424902.497601.32420K562APOBEC3C
POLE4ENSG00000115350.7227.80180164.541500.469202.198201.39210K562ATP5C1
POLE4ENSG00000115350.763.04290120.12370-0.930103.117302.18950K562BOP1
POLE4ENSG00000115350.7275.10110191.566300.522002.449901.65320K562FIP1L1
POLE4ENSG00000115350.774.84850129.95770-0.796002.673101.83360K562FMR1
POLE4ENSG00000115350.7292.09230203.478100.521502.945402.32380K562FXR1
POLE4ENSG00000115350.7834.76090422.775700.981406.644205.46730K562GRSF1
POLE4ENSG00000115350.7162.98110279.98640-0.780703.279401.54390K562HNRNPAB
POLE4ENSG00000115350.7247.90630157.554900.653802.927301.96650K562HNRNPM
POLE4ENSG00000115350.7250.44980166.420600.589602.744601.92220K562KIF1C
POLE4ENSG00000115350.7239.69740159.307700.589302.473401.47570K562MAK16
POLE4ENSG00000115350.7278.25620194.379900.517402.571001.68400K562MATR3
POLE4ENSG00000115350.7115.78810287.48050-1.312007.549605.52520K562PABPC1
POLE4ENSG00000115350.7360.18750217.449700.728004.876003.74040K562PPIG
POLE4ENSG00000115350.7359.52090187.904400.936003.330602.50540K562PRPF8
POLE4ENSG00000115350.7108.03090166.30870-0.622402.106701.32780K562PSIP1
POLE4ENSG00000115350.7270.84140189.252800.517002.775102.10950K562PTBP1
POLE4ENSG00000115350.7328.62350155.515101.079307.953007.07940K562PUS1
POLE4ENSG00000115350.7269.31340151.530600.829605.633104.81210K562RBM15
POLE4ENSG00000115350.7172.77560252.44210-0.547103.060902.20390K562SF3A3
POLE4ENSG00000115350.792.36400149.37220-0.693502.941602.05820K562SF3B4
POLE4ENSG00000115350.7308.48570185.539200.733404.669003.75490K562SRSF1
POLE4ENSG00000115350.793.04080159.94970-0.781703.011102.03110K562TIAL1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for POLE4 is not available on ENCORE database.






No RBPs affect the alternative splcing events of POLE4 on ENCORE database.





The Knockdown/knockout RNA-Seq assay for POLE4 is not avaliable on ENCORE database.