MEST

General Information

Gene Name       : MEST
Gene ID             : ENSG00000106484.15
Essential Gene : No

Functions

Localization

Domains (AlphaFold: MEST)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MESTENSG00000106484.158.216.937.57ENCSR000AEF
HepG2MESTENSG00000106484.1536.9339.7838.36ENCSR985KAT
K562MESTENSG00000106484.150.060.230.15ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MEST is not avaliable on ENCORE database.



Proteins bound to RNA
  • MEST RNA is bound by 2 proteins.  







eCLIP assay for MEST is not avaliable on ENCORE database.





2 proteins are bound to MEST RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr7130135213130135273+CDS5.082377.46114HepG2DDX3X
chr7130135987130136011+intron-Distal5.9361411.43966HepG2DGCR8
chr7130136074130136113+intron-Distal4.374333.88813HepG2DGCR8
chr7130136014130136024+intron-Distal5.8303010.59668HepG2DGCR8
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MEST is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MEST is not available on ENCORE database.

  • 86 RBPs can affect the levels of MEST.  








The Knockdown/knockout RNA-Seq assay for MEST is not available on ENCORE database.





86 RBPs can affect the gene expression of MEST :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MESTENSG00000106484.10642.24150966.86010-0.590209.651308.65580HepG2ACO1
MESTENSG00000106484.101528.887802024.35150-0.405002.736502.20720HepG2AKAP1
MESTENSG00000106484.10740.39540977.77740-0.401202.433201.45280HepG2AKAP8
MESTENSG00000106484.10607.34830971.32920-0.6774011.350509.93210HepG2AKAP8L
MESTENSG00000106484.10514.59810700.84410-0.445602.660701.77790HepG2BCLAF1
MESTENSG00000106484.10613.05430827.37530-0.432503.686002.27350HepG2BUD13
MESTENSG00000106484.101181.55120938.929200.331502.741301.97280HepG2CALR
MESTENSG00000106484.10430.522601591.35330-1.8861046.0756043.60390HepG2CIRBP
MESTENSG00000106484.10977.63540602.022500.699407.328706.25190HepG2CPSF6
MESTENSG00000106484.10707.39780909.40210-0.362402.858901.73540HepG2CPSF7
MESTENSG00000106484.10986.325201273.58510-0.368804.500303.71550HepG2CELF1
MESTENSG00000106484.101081.833001369.56390-0.340205.146804.18210HepG2DAZAP1
MESTENSG00000106484.101112.03210888.593700.323502.562901.68640HepG2DDX24
MESTENSG00000106484.101301.859201939.19650-0.574905.680304.81380HepG2DDX3X
MESTENSG00000106484.10154.30250793.06040-2.3617043.5229041.08200HepG2DDX55
MESTENSG00000106484.101124.187601665.76060-0.567304.771603.98020HepG2DDX6
MESTENSG00000106484.10486.13500823.90760-0.7611014.4718013.09660HepG2DNAJC2
MESTENSG00000106484.10570.04840741.50710-0.379402.347401.32890HepG2EFTUD2
MESTENSG00000106484.10772.233001601.38500-1.0522015.9741014.62570HepG2EIF2S1
MESTENSG00000106484.10581.83190837.72440-0.525905.253103.67010HepG2EIF2S2
MESTENSG00000106484.10395.19980722.06730-0.869608.422006.92750HepG2EIF3D
MESTENSG00000106484.101236.906001769.74240-0.516804.180503.39960HepG2EIF4A3
MESTENSG00000106484.10782.336701723.04740-1.1391013.3450011.89700HepG2EIF4B
MESTENSG00000106484.10864.046801351.03200-0.6449012.5008010.97670HepG2EIF4G1
MESTENSG00000106484.101178.403701745.56800-0.5669010.997709.92880HepG2ETF1
MESTENSG00000106484.10712.086501115.24460-0.647205.220704.19190HepG2FIP1L1
MESTENSG00000106484.101016.031401785.52420-0.8134010.587209.31850HepG2FXR1
MESTENSG00000106484.10805.745101656.37320-1.0396015.0122013.52410HepG2G3BP1
MESTENSG00000106484.10563.77020941.56620-0.740007.146405.49790HepG2GNB2L1
MESTENSG00000106484.10587.283201258.59740-1.0997029.0134026.62820HepG2HNRNPA2B1
MESTENSG00000106484.10402.45820933.48990-1.2138019.5180017.83740HepG2HNRNPC
MESTENSG00000106484.10647.722801247.61260-0.9457027.3597025.50220HepG2HNRNPL
MESTENSG00000106484.10618.04510927.31890-0.585408.759207.72670HepG2HNRNPU
MESTENSG00000106484.10847.455801683.68060-0.9904014.8541013.42940HepG2IGF2BP2
MESTENSG00000106484.10653.82340947.22720-0.534808.496207.28020HepG2ILF2
MESTENSG00000106484.10569.99590911.53310-0.677304.567402.85020HepG2ILF3
MESTENSG00000106484.101094.413201693.46990-0.629805.048503.65790HepG2KHSRP
MESTENSG00000106484.101497.529101153.261100.376802.148801.42470HepG2LARP4
MESTENSG00000106484.101016.888201786.14730-0.8127010.159308.92630HepG2MAGOH
MESTENSG00000106484.10553.57950781.14470-0.496803.597501.76650HepG2MARK2
MESTENSG00000106484.10911.796001796.15580-0.9781012.9313011.64110HepG2MATR3
MESTENSG00000106484.10509.18100902.44070-0.8257011.190709.67670HepG2MSI2
MESTENSG00000106484.10553.313001838.47480-1.7323038.3606036.20920HepG2NCBP2
MESTENSG00000106484.10690.260101008.87890-0.547503.367101.78250HepG2NKRF
MESTENSG00000106484.10255.38550854.54500-1.7425018.6389016.31860HepG2PABPC1
MESTENSG00000106484.10748.469901637.32520-1.1293018.1682016.37360HepG2PABPC4
MESTENSG00000106484.101029.529301708.54310-0.7308018.1235016.78880HepG2PCBP1
MESTENSG00000106484.101350.55410928.911400.539809.107207.81970HepG2PRPF4
MESTENSG00000106484.10844.366701738.49530-1.0419033.0091031.54080HepG2PTBP1
MESTENSG00000106484.101819.846301296.335600.489305.491904.68840HepG2PUF60
MESTENSG00000106484.10920.718801376.06960-0.5797013.1952012.10370HepG2PUM1
MESTENSG00000106484.10724.85870984.79680-0.442105.880805.04360HepG2PUS1
MESTENSG00000106484.101359.648001882.85720-0.469706.743305.83050HepG2QKI
MESTENSG00000106484.10198.847801052.65700-2.4043031.6568029.54960HepG2RAVER1
MESTENSG00000106484.101932.067801458.982700.405105.758005.07890HepG2RBM22
MESTENSG00000106484.101369.378001708.80490-0.319502.894502.20720HepG2RBM25
MESTENSG00000106484.10547.89060903.20110-0.721205.804404.26310HepG2RCC2
MESTENSG00000106484.101114.189401934.78770-0.7962021.0812019.86130HepG2NELFE
MESTENSG00000106484.101267.365901801.97490-0.507709.498108.45860HepG2RECQL
MESTENSG00000106484.10605.25850913.09600-0.593206.096705.13930HepG2RPLP0
MESTENSG00000106484.10706.832301033.83250-0.548603.128902.12750HepG2RPS10
MESTENSG00000106484.10483.75420702.63010-0.538504.810304.02500HepG2RPS19
MESTENSG00000106484.10468.96260705.15640-0.588504.691503.48020HepG2SERBP1
MESTENSG00000106484.10456.04730644.57470-0.499203.608202.81150HepG2SF3B1
MESTENSG00000106484.101148.366001810.01810-0.6564014.9041013.69690HepG2SF3B4
MESTENSG00000106484.10686.94980963.05980-0.487407.378706.40630HepG2SMN1
MESTENSG00000106484.10514.78100717.20940-0.478402.156901.47050HepG2SNRNP70
MESTENSG00000106484.102072.579801647.886600.330705.501104.86110HepG2SRFBP1
MESTENSG00000106484.101533.805901889.25880-0.300704.148903.59880HepG2SRSF1
MESTENSG00000106484.10970.743201279.88520-0.398905.561104.71860HepG2SRSF5
MESTENSG00000106484.101013.451101537.00560-0.6008012.9402011.90340HepG2SRSF9
MESTENSG00000106484.101119.507501430.78950-0.353904.698904.06620HepG2SSB
MESTENSG00000106484.101267.578601455.63120-0.199602.175501.61160HepG2SUCLG1
MESTENSG00000106484.10565.67250752.92470-0.412503.427902.38930HepG2SUPT6H
MESTENSG00000106484.10541.94000789.46160-0.542703.667202.90420HepG2SUPV3L1
MESTENSG00000106484.10598.25880901.09900-0.590907.059706.32830HepG2TIAL1
MESTENSG00000106484.10649.36950909.11620-0.485406.438405.64270HepG2TRIM56
MESTENSG00000106484.101035.582301266.38680-0.290302.346001.54840HepG2TUFM
MESTENSG00000106484.10770.88760953.92510-0.307401.991001.44870HepG2U2AF1
MESTENSG00000106484.10642.401901340.39900-1.0611013.9305012.00840HepG2UBE2L3
MESTENSG00000106484.10355.98770466.34710-0.389602.031201.37980HepG2UCHL5
MESTENSG00000106484.10699.78420933.02180-0.415004.922004.03300HepG2UPF1
MESTENSG00000106484.10677.79790916.70110-0.435605.575704.67340HepG2ZC3H8
MESTENSG00000106484.10788.728001026.14970-0.379605.127004.44000HepG2ZNF622
MESTENSG00000106484.1036.3545010.670701.768403.188502.58670K562AGGF1
MESTENSG00000106484.1033.3259011.103801.585502.138701.56130K562AKAP8L
MESTENSG00000106484.1026.112406.672801.968302.236601.55850K562PRPF8
MESTENSG00000106484.1030.454406.796302.163702.881202.04640K562RPS19
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MEST is not available on ENCORE database.





3 RBPs can affect the splicing of MEST :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEMESTENSG00000106484.10chr7+130140629130140731130140302130140373130142484130142561-0.260000.000000.00000excludedHepG2U2AF1
SEMESTENSG00000106484.10chr7+130140629130140731130140302130140373130142484130142561-0.222000.000330.00557excludedHepG2U2AF2
MXEMESTENSG00000106484.10chr7+1301403021301403731301406291301407311301397151301397561301424841301425610.212000.000010.000281includedHepG2U2AF1
MXEMESTENSG00000106484.10chr7+130140302130140373130140629130140731130139715130139756130142484130142561-0.142000.010530.082372includedHepG2SFPQ

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MEST is not avaliable on ENCORE database.