MBD2

General Information

Gene Name       : MBD2
Gene ID             : ENSG00000134046.11
Essential Gene : No

Functions

Localization

Domains (AlphaFold: MBD2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MBD2ENSG00000134046.1161.3958.5159.95ENCSR000AEF
HepG2MBD2ENSG00000134046.1119.9917.6618.82ENCSR985KAT
K562MBD2ENSG00000134046.1111.7014.5913.14ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MBD2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • MBD2 RNA is bound by 23 proteins.  







eCLIP assay for MBD2 is not avaliable on ENCORE database.





23 proteins are bound to MBD2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr185168121951681280-3'-UTR,intron-Distal4.0035114.02202K562PUM2
chr185169097751691073-3'-UTR,CDS,intron-Distal,intron-Proximal4.602516.73025HepG2GRWD1
chr185168154851681623-3'-UTR,intron-Distal,intron-Proximal3.665304.46864HepG2BCLAF1
chr185169089451690959-3'-UTR,CDS,intron-Distal3.053363.73997K562ZNF622
chr185169098251691071-3'-UTR,CDS,intron-Distal,intron-Proximal4.073754.32914K562YBX3
chr185168613451686223-3'-UTR,CDS,intron-Distal,intron-Proximal3.102544.51709HepG2BCLAF1
chr185168158551681681-3'-UTR,intron-Distal,intron-Proximal3.359803.80299HepG2GRWD1
chr185169244751692528-3'-UTR,CDS,intron-Distal3.287864.85828HepG2BCLAF1
chr185175078051750972-5'-UTR,CDS,intron-Distal3.380338.39715HepG2PRPF4
chr185175091451750946-5'-UTR,CDS,intron-Distal4.045383.24157K562GEMIN5
chr185175085751750954-5'-UTR,CDS,intron-Distal3.649045.55220K562CSTF2T
chr185175038751750461-CDS,intron-Distal3.239354.92880K562ZNF622
chr185175078851750838-CDS,intron-Distal3.799463.97432K562GEMIN5
chr185175060851750663-CDS,intron-Distal3.356523.76880HepG2DDX3X
chr185175068451750759-CDS,intron-Distal4.323823.98581K562PUM1
chr185175078151750867-CDS,intron-Distal3.681824.50290K562GTF2F1
chr185173138551731461-CDS,intron-Distal,intron-Proximal3.554104.09885HepG2BCLAF1
chr185175062051750756-CDS,intron-Distal5.145609.91068HepG2PRPF4
chr185175068451750803-CDS,intron-Distal4.3908814.52214HepG2GRSF1
chr185175080351750879-CDS,intron-Distal5.5265011.88632HepG2GRSF1
chr185175078151750876-CDS,intron-Distal4.424375.05409HepG2NCBP2
chr185175086351750916-CDS,intron-Distal5.633447.28656K562DROSHA
chr185175048351750559-CDS,intron-Distal4.178165.25366HepG2GRSF1
chr185175038751750442-CDS,intron-Distal4.220393.02457HepG2BCLAF1
chr185171526551715331-CDS,intron-Distal4.119858.55824K562IGF2BP1
chr185175055951750684-CDS,intron-Distal4.955389.11523HepG2GRSF1
chr185175062851750746-CDS,intron-Distal3.444907.05394K562DROSHA
chr185173146751731522-CDS,intron-Distal,intron-Proximal3.152333.02345K562ZNF622
chr185170975051709825-intron-Distal4.4675810.55454HepG2PTBP1
chr185174871751748732-intron-Distal4.12595400.00000HepG2DKC1
chr185174868751748690-intron-Distal3.88830400.00000HepG2DKC1
chr185174870051748711-intron-Distal3.94394400.00000HepG2DKC1
chr185173326351733308-intron-Distal5.091988.04096K562EXOSC5
chr185174873951748742-intron-Distal4.52970400.00000HepG2DKC1
chr185174865451748661-intron-Distal6.8110536.42906HepG2NOLC1
chr185174866151748709-intron-Distal3.56284400.00000HepG2NOLC1
chr185174865151748655-intron-Distal4.94974400.00000HepG2DKC1
chr185173336051733437-intron-Distal5.083027.38793K562EXOSC5
chr185170952151709618-intron-Distal4.794806.23638HepG2QKI
chr185174871151748717-intron-Distal4.18610400.00000HepG2DKC1
chr185174874251748777-intron-Distal4.38705400.00000HepG2DKC1
chr185170577151705873-intron-Distal5.178598.94695K562KHSRP
chr185174877751748782-intron-Distal4.08522400.00000HepG2DKC1
chr185174873551748739-intron-Distal4.32904400.00000HepG2DKC1
chr185174687451746958-intron-Distal5.6148010.79727HepG2QKI
chr185170977251709852-intron-Distal4.554057.96448K562PTBP1
chr185174871151748713-intron-Distal3.42741400.00000HepG2NOLC1
chr185174873251748735-intron-Distal4.02613400.00000HepG2DKC1
chr185174869751748698-intron-Distal3.89359400.00000HepG2DKC1
chr185174871351748737-intron-Distal3.28668400.00000HepG2NOLC1
chr185170451251704606-intron-Distal3.992463.66668K562KHSRP
chr185174869051748694-intron-Distal3.98143400.00000HepG2DKC1
chr185170975351709838-intron-Distal4.471335.51760K562MATR3
chr185168712051687184-intron-Distal4.524603.92866K562PTBP1
chr185170926051709304-intron-Distal4.025973.86809HepG2SUGP2
chr185174865951748687-intron-Distal4.39237400.00000HepG2DKC1
chr185173352251733573-intron-Distal3.536473.43875K562EXOSC5
chr185174819751748279-intron-Distal4.097303.01456K562EXOSC5
chr185175018951750269-intron-Distal4.232964.35952HepG2PRPF4
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MBD2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MBD2 is not available on ENCORE database.

  • 72 RBPs can affect the levels of MBD2.  








The Knockdown/knockout RNA-Seq assay for MBD2 is not available on ENCORE database.





72 RBPs can affect the gene expression of MBD2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MBD2ENSG00000134046.7780.12540574.199700.442103.843203.14820HepG2ACO1
MBD2ENSG00000134046.71167.72550609.207300.9386010.003309.05840HepG2AKAP1
MBD2ENSG00000134046.7811.18200504.065300.686306.043104.90510HepG2ASCC1
MBD2ENSG00000134046.7984.36380776.528800.342102.756201.52520HepG2BUD13
MBD2ENSG00000134046.7808.61690478.897500.755607.318506.10700HepG2CIRBP
MBD2ENSG00000134046.7691.13480903.26530-0.386204.830003.89100HepG2DAZAP1
MBD2ENSG00000134046.7649.56520531.103600.290402.035401.31050HepG2DDX19B
MBD2ENSG00000134046.7363.07170583.56890-0.684605.059104.23500HepG2DDX3X
MBD2ENSG00000134046.7901.42380620.917200.537704.875603.18660HepG2DDX47
MBD2ENSG00000134046.7363.24000524.48910-0.530003.069302.26160HepG2DDX55
MBD2ENSG00000134046.7275.90370501.31080-0.861506.348305.44180HepG2DDX6
MBD2ENSG00000134046.7707.55800549.382300.364903.090402.38030HepG2DKC1
MBD2ENSG00000134046.7348.10170498.38530-0.517802.726701.62980HepG2AGO1
MBD2ENSG00000134046.71021.31410786.221900.377303.323402.03310HepG2EIF2S2
MBD2ENSG00000134046.7719.27000504.853200.510603.763902.71980HepG2EIF3D
MBD2ENSG00000134046.71286.17690891.085200.529403.075202.20130HepG2EIF4G1
MBD2ENSG00000134046.71207.94770928.173100.380004.930604.16910HepG2ETF1
MBD2ENSG00000134046.7253.96620451.18060-0.829108.278506.23000HepG2FAM120A
MBD2ENSG00000134046.71609.529401046.394200.621105.586704.53040HepG2FIP1L1
MBD2ENSG00000134046.7588.352901167.43310-0.988604.916103.56910HepG2FTO
MBD2ENSG00000134046.7621.74270449.511500.467902.727401.83590HepG2GEMIN5
MBD2ENSG00000134046.7899.761301321.16200-0.554203.699102.96790HepG2GPKOW
MBD2ENSG00000134046.7637.33550830.10350-0.381203.731602.67070HepG2HNRNPA2B1
MBD2ENSG00000134046.7777.19060917.07540-0.238801.918801.31410HepG2HNRNPF
MBD2ENSG00000134046.7558.64920822.82010-0.558608.200307.09540HepG2HNRNPL
MBD2ENSG00000134046.7566.33260722.07740-0.350502.188201.34210HepG2HNRNPM
MBD2ENSG00000134046.7856.35210506.671000.757107.448906.39730HepG2IGF2BP2
MBD2ENSG00000134046.71042.35600847.058200.299202.273801.53830HepG2MSI2
MBD2ENSG00000134046.7252.23060553.27330-1.1332011.2538010.01890HepG2NCBP2
MBD2ENSG00000134046.7802.37200536.794200.579807.734206.80040HepG2PCBP1
MBD2ENSG00000134046.71073.57850693.583500.630203.928502.48920HepG2PRPF6
MBD2ENSG00000134046.7737.20110546.230700.432404.286903.63810HepG2PTBP1
MBD2ENSG00000134046.7538.75160854.98530-0.666307.341506.42990HepG2PUF60
MBD2ENSG00000134046.7514.28960906.93580-0.8184011.9928010.65310HepG2PUM2
MBD2ENSG00000134046.7843.18010584.876000.527607.186806.27240HepG2PUS1
MBD2ENSG00000134046.7396.85910591.53350-0.575805.040604.23540HepG2QKI
MBD2ENSG00000134046.7346.48350636.73490-0.877904.996804.06390HepG2RAVER1
MBD2ENSG00000134046.7565.92160775.78600-0.455104.240003.63370HepG2RBM22
MBD2ENSG00000134046.7757.79960536.872700.497104.384103.55200HepG2RBM25
MBD2ENSG00000134046.7845.00620607.883600.475105.163104.46170HepG2NELFE
MBD2ENSG00000134046.7703.84470493.048500.513403.908602.79200HepG2SERBP1
MBD2ENSG00000134046.71386.36760933.711700.570203.982203.16650HepG2SF3A3
MBD2ENSG00000134046.7634.45120819.76540-0.369703.987503.16820HepG2SLBP
MBD2ENSG00000134046.71275.11280876.230700.541109.306508.53680HepG2SRFBP1
MBD2ENSG00000134046.7975.018501342.77070-0.461702.998301.94870HepG2SRSF3
MBD2ENSG00000134046.7729.97840900.99690-0.303702.805502.10470HepG2SRSF7
MBD2ENSG00000134046.7608.88270482.915400.334302.720902.17290HepG2SRSF9
MBD2ENSG00000134046.7970.09990760.791400.350503.858103.27510HepG2SSB
MBD2ENSG00000134046.7390.26170533.56990-0.451203.420702.80780HepG2TAF15
MBD2ENSG00000134046.7990.657501228.82490-0.310802.117301.47100HepG2TARDBP
MBD2ENSG00000134046.71159.45300895.222000.373002.704502.08190HepG2U2AF1
MBD2ENSG00000134046.7629.32620851.14110-0.435604.656903.33640HepG2UTP18
MBD2ENSG00000134046.71140.63630799.459900.512607.706706.78780HepG2UTP3
MBD2ENSG00000134046.7998.81740773.168100.369304.525403.70030HepG2ZC3H8
MBD2ENSG00000134046.71261.99320910.707500.470508.460207.63830HepG2ZNF622
MBD2ENSG00000134046.7769.95360555.175600.471703.722702.33320K562AARS
MBD2ENSG00000134046.71075.05660845.633900.346203.628002.99390K562AGGF1
MBD2ENSG00000134046.71282.06400992.159600.369702.863001.37470K562DDX19B
MBD2ENSG00000134046.71619.502301371.798100.239402.519001.89280K562DDX47
MBD2ENSG00000134046.71337.02810946.884000.497704.089502.99470K562DKC1
MBD2ENSG00000134046.7610.92410470.820000.375702.884002.07320K562EIF3G
MBD2ENSG00000134046.7717.94210527.344100.445002.850501.70390K562FKBP4
MBD2ENSG00000134046.71054.917001507.09650-0.514605.270104.08320K562FMR1
MBD2ENSG00000134046.7938.053901277.37470-0.445403.066002.09810K562FTO
MBD2ENSG00000134046.7726.59330450.158200.690608.846207.83790K562FXR1
MBD2ENSG00000134046.7739.92700483.194100.614703.993603.10580K562G3BP2
MBD2ENSG00000134046.71082.966701414.27100-0.385102.617801.84330K562GPKOW
MBD2ENSG00000134046.7938.210201239.71990-0.402003.729902.47750K562HNRNPL
MBD2ENSG00000134046.7375.59770558.08830-0.571304.932903.65930K562MATR3
MBD2ENSG00000134046.71135.28810733.253300.630604.645303.40770K562NAA15
MBD2ENSG00000134046.7621.01780414.355200.583704.156003.23680K562PRPF8
MBD2ENSG00000134046.72105.456401522.242900.467806.962305.21110K562PUM1
MBD2ENSG00000134046.71460.24390872.671200.742603.536902.93480K562PUS1
MBD2ENSG00000134046.71110.91260850.256200.385703.875003.18990K562RBM15
MBD2ENSG00000134046.7880.95450621.673100.502804.543603.14840K562SAFB
MBD2ENSG00000134046.7872.38330642.675100.440803.267201.68490K562SDAD1
MBD2ENSG00000134046.7742.90210990.56600-0.415104.051002.93870K562SRPK2
MBD2ENSG00000134046.71044.92060699.720900.578404.669403.59520K562SYNCRIP
MBD2ENSG00000134046.7730.83710468.145700.642504.944603.39650K562U2AF1
MBD2ENSG00000134046.7677.06310483.566700.485504.265303.27240K562U2AF2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MBD2 is not available on ENCORE database.





5 RBPs can affect the splicing of MBD2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEMBD2ENSG00000134046.7chr18-516924455169253651690892516910705171524351715441-0.067000.000000.00004excludedK562AQR
SEMBD2ENSG00000134046.7chr18-5171408351714224516924455169253651715243517153810.054000.000240.06449includedK562PPIL4
A3SSMBD2ENSG00000134046.7chr18-5168613451686299516861345168627351690892516910700.075000.000000.00000longerK562AQR
MXEMBD2ENSG00000134046.7chr18-51692445516925365171408351714207516908925169107051715243517153810.052000.000550.023461includedHepG2TAF15
MXEMBD2ENSG00000134046.7chr18-51692445516925365171524351715371516908925169107051731367517315270.067000.000000.000071includedK562AQR
MXEMBD2ENSG00000134046.7chr18-51692445516925365171524351715441516908925169107051731367517315270.067000.000000.000071includedK562AQR
MXEMBD2ENSG00000134046.7chr18-51692445516925365171524351715371516908925169107051731367517315270.077000.007510.075591includedK562U2AF2
MXEMBD2ENSG00000134046.7chr18-51692445516925365171524351715381516908925169107051731367517315270.145000.000700.027741includedK562DDX55

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MBD2 is not avaliable on ENCORE database.