MBD2

General Information

Gene Name : MBD2
Gene ID : ENSG00000134046.11
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: MBD2)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	MBD2	ENSG00000134046.11	61.39	58.51	59.95	ENCSR000AEF
HepG2	MBD2	ENSG00000134046.11	19.99	17.66	18.82	ENCSR985KAT
K562	MBD2	ENSG00000134046.11	11.70	14.59	13.14	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for MBD2 is not avaliable on ENCORE database.

Proteins bound to RNA

MBD2 RNA is bound by 23 proteins.

CanvasJS.com

eCLIP assay for MBD2 is not avaliable on ENCORE database.

23 proteins are bound to MBD2 RNA:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr18	51681219	51681280	-	3'-UTR,intron-Distal	4.00351	14.02202	K562	PUM2
chr18	51690977	51691073	-	3'-UTR,CDS,intron-Distal,intron-Proximal	4.60251	6.73025	HepG2	GRWD1
chr18	51681548	51681623	-	3'-UTR,intron-Distal,intron-Proximal	3.66530	4.46864	HepG2	BCLAF1
chr18	51690894	51690959	-	3'-UTR,CDS,intron-Distal	3.05336	3.73997	K562	ZNF622
chr18	51690982	51691071	-	3'-UTR,CDS,intron-Distal,intron-Proximal	4.07375	4.32914	K562	YBX3
chr18	51686134	51686223	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.10254	4.51709	HepG2	BCLAF1
chr18	51681585	51681681	-	3'-UTR,intron-Distal,intron-Proximal	3.35980	3.80299	HepG2	GRWD1
chr18	51692447	51692528	-	3'-UTR,CDS,intron-Distal	3.28786	4.85828	HepG2	BCLAF1
chr18	51750780	51750972	-	5'-UTR,CDS,intron-Distal	3.38033	8.39715	HepG2	PRPF4
chr18	51750914	51750946	-	5'-UTR,CDS,intron-Distal	4.04538	3.24157	K562	GEMIN5
chr18	51750857	51750954	-	5'-UTR,CDS,intron-Distal	3.64904	5.55220	K562	CSTF2T
chr18	51750387	51750461	-	CDS,intron-Distal	3.23935	4.92880	K562	ZNF622
chr18	51750788	51750838	-	CDS,intron-Distal	3.79946	3.97432	K562	GEMIN5
chr18	51750608	51750663	-	CDS,intron-Distal	3.35652	3.76880	HepG2	DDX3X
chr18	51750684	51750759	-	CDS,intron-Distal	4.32382	3.98581	K562	PUM1
chr18	51750781	51750867	-	CDS,intron-Distal	3.68182	4.50290	K562	GTF2F1
chr18	51731385	51731461	-	CDS,intron-Distal,intron-Proximal	3.55410	4.09885	HepG2	BCLAF1
chr18	51750620	51750756	-	CDS,intron-Distal	5.14560	9.91068	HepG2	PRPF4
chr18	51750684	51750803	-	CDS,intron-Distal	4.39088	14.52214	HepG2	GRSF1
chr18	51750803	51750879	-	CDS,intron-Distal	5.52650	11.88632	HepG2	GRSF1
chr18	51750781	51750876	-	CDS,intron-Distal	4.42437	5.05409	HepG2	NCBP2
chr18	51750863	51750916	-	CDS,intron-Distal	5.63344	7.28656	K562	DROSHA
chr18	51750483	51750559	-	CDS,intron-Distal	4.17816	5.25366	HepG2	GRSF1
chr18	51750387	51750442	-	CDS,intron-Distal	4.22039	3.02457	HepG2	BCLAF1
chr18	51715265	51715331	-	CDS,intron-Distal	4.11985	8.55824	K562	IGF2BP1
chr18	51750559	51750684	-	CDS,intron-Distal	4.95538	9.11523	HepG2	GRSF1
chr18	51750628	51750746	-	CDS,intron-Distal	3.44490	7.05394	K562	DROSHA
chr18	51731467	51731522	-	CDS,intron-Distal,intron-Proximal	3.15233	3.02345	K562	ZNF622
chr18	51709750	51709825	-	intron-Distal	4.46758	10.55454	HepG2	PTBP1
chr18	51748717	51748732	-	intron-Distal	4.12595	400.00000	HepG2	DKC1
chr18	51748687	51748690	-	intron-Distal	3.88830	400.00000	HepG2	DKC1
chr18	51748700	51748711	-	intron-Distal	3.94394	400.00000	HepG2	DKC1
chr18	51733263	51733308	-	intron-Distal	5.09198	8.04096	K562	EXOSC5
chr18	51748739	51748742	-	intron-Distal	4.52970	400.00000	HepG2	DKC1
chr18	51748654	51748661	-	intron-Distal	6.81105	36.42906	HepG2	NOLC1
chr18	51748661	51748709	-	intron-Distal	3.56284	400.00000	HepG2	NOLC1
chr18	51748651	51748655	-	intron-Distal	4.94974	400.00000	HepG2	DKC1
chr18	51733360	51733437	-	intron-Distal	5.08302	7.38793	K562	EXOSC5
chr18	51709521	51709618	-	intron-Distal	4.79480	6.23638	HepG2	QKI
chr18	51748711	51748717	-	intron-Distal	4.18610	400.00000	HepG2	DKC1
chr18	51748742	51748777	-	intron-Distal	4.38705	400.00000	HepG2	DKC1
chr18	51705771	51705873	-	intron-Distal	5.17859	8.94695	K562	KHSRP
chr18	51748777	51748782	-	intron-Distal	4.08522	400.00000	HepG2	DKC1
chr18	51748735	51748739	-	intron-Distal	4.32904	400.00000	HepG2	DKC1
chr18	51746874	51746958	-	intron-Distal	5.61480	10.79727	HepG2	QKI
chr18	51709772	51709852	-	intron-Distal	4.55405	7.96448	K562	PTBP1
chr18	51748711	51748713	-	intron-Distal	3.42741	400.00000	HepG2	NOLC1
chr18	51748732	51748735	-	intron-Distal	4.02613	400.00000	HepG2	DKC1
chr18	51748697	51748698	-	intron-Distal	3.89359	400.00000	HepG2	DKC1
chr18	51748713	51748737	-	intron-Distal	3.28668	400.00000	HepG2	NOLC1
chr18	51704512	51704606	-	intron-Distal	3.99246	3.66668	K562	KHSRP
chr18	51748690	51748694	-	intron-Distal	3.98143	400.00000	HepG2	DKC1
chr18	51709753	51709838	-	intron-Distal	4.47133	5.51760	K562	MATR3
chr18	51687120	51687184	-	intron-Distal	4.52460	3.92866	K562	PTBP1
chr18	51709260	51709304	-	intron-Distal	4.02597	3.86809	HepG2	SUGP2
chr18	51748659	51748687	-	intron-Distal	4.39237	400.00000	HepG2	DKC1
chr18	51733522	51733573	-	intron-Distal	3.53647	3.43875	K562	EXOSC5
chr18	51748197	51748279	-	intron-Distal	4.09730	3.01456	K562	EXOSC5
chr18	51750189	51750269	-	intron-Distal	4.23296	4.35952	HepG2	PRPF4
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

eCLIP assay for MBD2 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for MBD2 is not available on ENCORE database.
72 RBPs can affect the levels of MBD2.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for MBD2 is not available on ENCORE database.

72 RBPs can affect the gene expression of MBD2 :

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
MBD2	ENSG00000134046.7	780.12540	574.19970	0.44210	3.84320	3.14820	HepG2	ACO1
MBD2	ENSG00000134046.7	1167.72550	609.20730	0.93860	10.00330	9.05840	HepG2	AKAP1
MBD2	ENSG00000134046.7	811.18200	504.06530	0.68630	6.04310	4.90510	HepG2	ASCC1
MBD2	ENSG00000134046.7	984.36380	776.52880	0.34210	2.75620	1.52520	HepG2	BUD13
MBD2	ENSG00000134046.7	808.61690	478.89750	0.75560	7.31850	6.10700	HepG2	CIRBP
MBD2	ENSG00000134046.7	691.13480	903.26530	-0.38620	4.83000	3.89100	HepG2	DAZAP1
MBD2	ENSG00000134046.7	649.56520	531.10360	0.29040	2.03540	1.31050	HepG2	DDX19B
MBD2	ENSG00000134046.7	363.07170	583.56890	-0.68460	5.05910	4.23500	HepG2	DDX3X
MBD2	ENSG00000134046.7	901.42380	620.91720	0.53770	4.87560	3.18660	HepG2	DDX47
MBD2	ENSG00000134046.7	363.24000	524.48910	-0.53000	3.06930	2.26160	HepG2	DDX55
MBD2	ENSG00000134046.7	275.90370	501.31080	-0.86150	6.34830	5.44180	HepG2	DDX6
MBD2	ENSG00000134046.7	707.55800	549.38230	0.36490	3.09040	2.38030	HepG2	DKC1
MBD2	ENSG00000134046.7	348.10170	498.38530	-0.51780	2.72670	1.62980	HepG2	AGO1
MBD2	ENSG00000134046.7	1021.31410	786.22190	0.37730	3.32340	2.03310	HepG2	EIF2S2
MBD2	ENSG00000134046.7	719.27000	504.85320	0.51060	3.76390	2.71980	HepG2	EIF3D
MBD2	ENSG00000134046.7	1286.17690	891.08520	0.52940	3.07520	2.20130	HepG2	EIF4G1
MBD2	ENSG00000134046.7	1207.94770	928.17310	0.38000	4.93060	4.16910	HepG2	ETF1
MBD2	ENSG00000134046.7	253.96620	451.18060	-0.82910	8.27850	6.23000	HepG2	FAM120A
MBD2	ENSG00000134046.7	1609.52940	1046.39420	0.62110	5.58670	4.53040	HepG2	FIP1L1
MBD2	ENSG00000134046.7	588.35290	1167.43310	-0.98860	4.91610	3.56910	HepG2	FTO
MBD2	ENSG00000134046.7	621.74270	449.51150	0.46790	2.72740	1.83590	HepG2	GEMIN5
MBD2	ENSG00000134046.7	899.76130	1321.16200	-0.55420	3.69910	2.96790	HepG2	GPKOW
MBD2	ENSG00000134046.7	637.33550	830.10350	-0.38120	3.73160	2.67070	HepG2	HNRNPA2B1
MBD2	ENSG00000134046.7	777.19060	917.07540	-0.23880	1.91880	1.31410	HepG2	HNRNPF
MBD2	ENSG00000134046.7	558.64920	822.82010	-0.55860	8.20030	7.09540	HepG2	HNRNPL
MBD2	ENSG00000134046.7	566.33260	722.07740	-0.35050	2.18820	1.34210	HepG2	HNRNPM
MBD2	ENSG00000134046.7	856.35210	506.67100	0.75710	7.44890	6.39730	HepG2	IGF2BP2
MBD2	ENSG00000134046.7	1042.35600	847.05820	0.29920	2.27380	1.53830	HepG2	MSI2
MBD2	ENSG00000134046.7	252.23060	553.27330	-1.13320	11.25380	10.01890	HepG2	NCBP2
MBD2	ENSG00000134046.7	802.37200	536.79420	0.57980	7.73420	6.80040	HepG2	PCBP1
MBD2	ENSG00000134046.7	1073.57850	693.58350	0.63020	3.92850	2.48920	HepG2	PRPF6
MBD2	ENSG00000134046.7	737.20110	546.23070	0.43240	4.28690	3.63810	HepG2	PTBP1
MBD2	ENSG00000134046.7	538.75160	854.98530	-0.66630	7.34150	6.42990	HepG2	PUF60
MBD2	ENSG00000134046.7	514.28960	906.93580	-0.81840	11.99280	10.65310	HepG2	PUM2
MBD2	ENSG00000134046.7	843.18010	584.87600	0.52760	7.18680	6.27240	HepG2	PUS1
MBD2	ENSG00000134046.7	396.85910	591.53350	-0.57580	5.04060	4.23540	HepG2	QKI
MBD2	ENSG00000134046.7	346.48350	636.73490	-0.87790	4.99680	4.06390	HepG2	RAVER1
MBD2	ENSG00000134046.7	565.92160	775.78600	-0.45510	4.24000	3.63370	HepG2	RBM22
MBD2	ENSG00000134046.7	757.79960	536.87270	0.49710	4.38410	3.55200	HepG2	RBM25
MBD2	ENSG00000134046.7	845.00620	607.88360	0.47510	5.16310	4.46170	HepG2	NELFE
MBD2	ENSG00000134046.7	703.84470	493.04850	0.51340	3.90860	2.79200	HepG2	SERBP1
MBD2	ENSG00000134046.7	1386.36760	933.71170	0.57020	3.98220	3.16650	HepG2	SF3A3
MBD2	ENSG00000134046.7	634.45120	819.76540	-0.36970	3.98750	3.16820	HepG2	SLBP
MBD2	ENSG00000134046.7	1275.11280	876.23070	0.54110	9.30650	8.53680	HepG2	SRFBP1
MBD2	ENSG00000134046.7	975.01850	1342.77070	-0.46170	2.99830	1.94870	HepG2	SRSF3
MBD2	ENSG00000134046.7	729.97840	900.99690	-0.30370	2.80550	2.10470	HepG2	SRSF7
MBD2	ENSG00000134046.7	608.88270	482.91540	0.33430	2.72090	2.17290	HepG2	SRSF9
MBD2	ENSG00000134046.7	970.09990	760.79140	0.35050	3.85810	3.27510	HepG2	SSB
MBD2	ENSG00000134046.7	390.26170	533.56990	-0.45120	3.42070	2.80780	HepG2	TAF15
MBD2	ENSG00000134046.7	990.65750	1228.82490	-0.31080	2.11730	1.47100	HepG2	TARDBP
MBD2	ENSG00000134046.7	1159.45300	895.22200	0.37300	2.70450	2.08190	HepG2	U2AF1
MBD2	ENSG00000134046.7	629.32620	851.14110	-0.43560	4.65690	3.33640	HepG2	UTP18
MBD2	ENSG00000134046.7	1140.63630	799.45990	0.51260	7.70670	6.78780	HepG2	UTP3
MBD2	ENSG00000134046.7	998.81740	773.16810	0.36930	4.52540	3.70030	HepG2	ZC3H8
MBD2	ENSG00000134046.7	1261.99320	910.70750	0.47050	8.46020	7.63830	HepG2	ZNF622
MBD2	ENSG00000134046.7	769.95360	555.17560	0.47170	3.72270	2.33320	K562	AARS
MBD2	ENSG00000134046.7	1075.05660	845.63390	0.34620	3.62800	2.99390	K562	AGGF1
MBD2	ENSG00000134046.7	1282.06400	992.15960	0.36970	2.86300	1.37470	K562	DDX19B
MBD2	ENSG00000134046.7	1619.50230	1371.79810	0.23940	2.51900	1.89280	K562	DDX47
MBD2	ENSG00000134046.7	1337.02810	946.88400	0.49770	4.08950	2.99470	K562	DKC1
MBD2	ENSG00000134046.7	610.92410	470.82000	0.37570	2.88400	2.07320	K562	EIF3G
MBD2	ENSG00000134046.7	717.94210	527.34410	0.44500	2.85050	1.70390	K562	FKBP4
MBD2	ENSG00000134046.7	1054.91700	1507.09650	-0.51460	5.27010	4.08320	K562	FMR1
MBD2	ENSG00000134046.7	938.05390	1277.37470	-0.44540	3.06600	2.09810	K562	FTO
MBD2	ENSG00000134046.7	726.59330	450.15820	0.69060	8.84620	7.83790	K562	FXR1
MBD2	ENSG00000134046.7	739.92700	483.19410	0.61470	3.99360	3.10580	K562	G3BP2
MBD2	ENSG00000134046.7	1082.96670	1414.27100	-0.38510	2.61780	1.84330	K562	GPKOW
MBD2	ENSG00000134046.7	938.21020	1239.71990	-0.40200	3.72990	2.47750	K562	HNRNPL
MBD2	ENSG00000134046.7	375.59770	558.08830	-0.57130	4.93290	3.65930	K562	MATR3
MBD2	ENSG00000134046.7	1135.28810	733.25330	0.63060	4.64530	3.40770	K562	NAA15
MBD2	ENSG00000134046.7	621.01780	414.35520	0.58370	4.15600	3.23680	K562	PRPF8
MBD2	ENSG00000134046.7	2105.45640	1522.24290	0.46780	6.96230	5.21110	K562	PUM1
MBD2	ENSG00000134046.7	1460.24390	872.67120	0.74260	3.53690	2.93480	K562	PUS1
MBD2	ENSG00000134046.7	1110.91260	850.25620	0.38570	3.87500	3.18990	K562	RBM15
MBD2	ENSG00000134046.7	880.95450	621.67310	0.50280	4.54360	3.14840	K562	SAFB
MBD2	ENSG00000134046.7	872.38330	642.67510	0.44080	3.26720	1.68490	K562	SDAD1
MBD2	ENSG00000134046.7	742.90210	990.56600	-0.41510	4.05100	2.93870	K562	SRPK2
MBD2	ENSG00000134046.7	1044.92060	699.72090	0.57840	4.66940	3.59520	K562	SYNCRIP
MBD2	ENSG00000134046.7	730.83710	468.14570	0.64250	4.94460	3.39650	K562	U2AF1
MBD2	ENSG00000134046.7	677.06310	483.56670	0.48550	4.26530	3.27240	K562	U2AF2
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for MBD2 is not available on ENCORE database.

5 RBPs can affect the splicing of MBD2 :

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	MBD2	ENSG00000134046.7	chr18	-	51692445	51692536			51690892	51691070	51715243	51715441	-0.06700	0.00000	0.00004	excluded	K562	AQR
SE	MBD2	ENSG00000134046.7	chr18	-	51714083	51714224			51692445	51692536	51715243	51715381	0.05400	0.00024	0.06449	included	K562	PPIL4
A3SS	MBD2	ENSG00000134046.7	chr18	-	51686134	51686299			51686134	51686273	51690892	51691070	0.07500	0.00000	0.00000	longer	K562	AQR
MXE	MBD2	ENSG00000134046.7	chr18	-	51692445	51692536	51714083	51714207	51690892	51691070	51715243	51715381	0.05200	0.00055	0.02346	1included	HepG2	TAF15
MXE	MBD2	ENSG00000134046.7	chr18	-	51692445	51692536	51715243	51715371	51690892	51691070	51731367	51731527	0.06700	0.00000	0.00007	1included	K562	AQR
MXE	MBD2	ENSG00000134046.7	chr18	-	51692445	51692536	51715243	51715441	51690892	51691070	51731367	51731527	0.06700	0.00000	0.00007	1included	K562	AQR
MXE	MBD2	ENSG00000134046.7	chr18	-	51692445	51692536	51715243	51715371	51690892	51691070	51731367	51731527	0.07700	0.00751	0.07559	1included	K562	U2AF2
MXE	MBD2	ENSG00000134046.7	chr18	-	51692445	51692536	51715243	51715381	51690892	51691070	51731367	51731527	0.14500	0.00070	0.02774	1included	K562	DDX55

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

MBD2

General Information

Functions

Localization

Domains (AlphaFold: MBD2)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for MBD2 is not avaliable on ENCORE database.

23 proteins are bound to MBD2 RNA:

eCLIP assay for MBD2 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for MBD2 is not available on ENCORE database.

72 RBPs can affect the gene expression of MBD2 :

The Knockdown/knockout RNA-Seq assay for MBD2 is not available on ENCORE database.

5 RBPs can affect the splicing of MBD2 :

The Knockdown/knockout RNA-Seq assay for MBD2 is not avaliable on ENCORE database.