LAMTOR2

General Information

Gene Name       : LAMTOR2
Gene ID             : ENSG00000116586.11
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: LAMTOR2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878LAMTOR2ENSG00000116586.1122.0348.9335.48ENCSR000AEF
HepG2LAMTOR2ENSG00000116586.1169.0446.2457.64ENCSR985KAT
K562LAMTOR2ENSG00000116586.1158.9643.0250.99ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for LAMTOR2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • LAMTOR2 RNA is bound by 6 proteins.  







eCLIP assay for LAMTOR2 is not avaliable on ENCORE database.





6 proteins are bound to LAMTOR2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1156028197156028257+3'-UTR3.652774.08867HepG2LARP4
chr1156028104156028169+3'-UTR,CDS,intron-Proximal3.875185.75263HepG2LARP4
chr1156024636156024710+5'-UTR,CDS4.745415.00258K562FTO
chr1156024666156024740+5'-UTR,CDS5.0731011.81272K562DDX3X
chr1156024606156024746+5'-UTR,CDS3.113518.45630K562YBX3
chr1156025059156025170+CDS3.5617011.71300K562YBX3
chr1156025190156025223+CDS,intron-Proximal3.117363.12941K562UCHL5
chr1156025060156025108+CDS3.767714.84938K562DDX3X
chr1156027766156027813+CDS,intron-Distal,intron-Proximal3.366973.73423K562UCHL5
chr1156025168156025247+CDS,intron-Proximal3.950083.12746HepG2GRWD1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for LAMTOR2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for LAMTOR2 is not available on ENCORE database.

  • 69 RBPs can affect the levels of LAMTOR2.  








The Knockdown/knockout RNA-Seq assay for LAMTOR2 is not available on ENCORE database.





69 RBPs can affect the gene expression of LAMTOR2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
LAMTOR2ENSG00000116586.7171.78330248.66650-0.533602.360301.36650HepG2AATF
LAMTOR2ENSG00000116586.7867.96270462.737300.907308.427307.55410HepG2AKAP1
LAMTOR2ENSG00000116586.7486.22350363.760100.418502.173601.48320HepG2CIRBP
LAMTOR2ENSG00000116586.7370.74820243.162400.608402.528801.79890HepG2CNOT7
LAMTOR2ENSG00000116586.7205.87260291.12730-0.499902.232001.60620HepG2CPSF6
LAMTOR2ENSG00000116586.7365.44190267.862400.448002.801201.96220HepG2DDX19B
LAMTOR2ENSG00000116586.7411.00760274.421600.582703.730702.95300HepG2DDX21
LAMTOR2ENSG00000116586.7178.32210268.48710-0.590403.066902.10420HepG2DDX24
LAMTOR2ENSG00000116586.7602.66180443.271900.443102.511701.91320HepG2DDX3X
LAMTOR2ENSG00000116586.7513.09480306.073000.745204.407303.45320HepG2DDX55
LAMTOR2ENSG00000116586.7200.17500330.59570-0.723802.894401.89340HepG2DDX59
LAMTOR2ENSG00000116586.7289.52380226.274800.355501.941601.37750HepG2DNAJC2
LAMTOR2ENSG00000116586.7393.92940499.19390-0.341702.428801.85870HepG2ETF1
LAMTOR2ENSG00000116586.7382.97360282.988700.436402.452501.66510HepG2EWSR1
LAMTOR2ENSG00000116586.7346.26050232.459600.574802.610101.52570HepG2FUS
LAMTOR2ENSG00000116586.7393.31360256.337600.617503.759402.96100HepG2HNRNPC
LAMTOR2ENSG00000116586.7248.44180399.85070-0.686603.262102.48840HepG2HNRNPF
LAMTOR2ENSG00000116586.7146.21470383.37060-1.3907013.3138011.89020HepG2HNRNPK
LAMTOR2ENSG00000116586.7295.46440439.11140-0.571602.779802.10480HepG2HNRNPL
LAMTOR2ENSG00000116586.7182.30980314.94520-0.788704.574603.78500HepG2HNRNPLL
LAMTOR2ENSG00000116586.7231.01200384.86460-0.736404.574303.72610HepG2IGF2BP2
LAMTOR2ENSG00000116586.7269.63330387.10260-0.521702.207301.32450HepG2KHSRP
LAMTOR2ENSG00000116586.7604.55360410.575200.558103.371602.68160HepG2MATR3
LAMTOR2ENSG00000116586.7174.78170255.30660-0.546702.617901.43640HepG2NAA15
LAMTOR2ENSG00000116586.7358.25510231.340500.630903.036501.53460HepG2NKRF
LAMTOR2ENSG00000116586.7187.91380279.25470-0.571502.432701.73030HepG2NSUN2
LAMTOR2ENSG00000116586.7344.38540252.038200.450302.748201.90270HepG2PARN
LAMTOR2ENSG00000116586.7458.94100355.610700.367902.471201.94970HepG2PTBP1
LAMTOR2ENSG00000116586.7646.72390484.544100.416403.766903.09800HepG2PUM1
LAMTOR2ENSG00000116586.7344.56540484.15650-0.490701.859801.30440HepG2PUM2
LAMTOR2ENSG00000116586.7591.50980417.225800.503504.156503.55460HepG2RBM22
LAMTOR2ENSG00000116586.7162.99750349.53490-1.100609.946308.72500HepG2RBM25
LAMTOR2ENSG00000116586.7258.05920430.61640-0.738703.685802.91570HepG2RPLP0
LAMTOR2ENSG00000116586.7415.37130204.990301.018709.369208.31750HepG2RPS19
LAMTOR2ENSG00000116586.7479.33570309.678400.630204.052303.09230HepG2RPS2
LAMTOR2ENSG00000116586.7105.53700231.13330-1.131004.225202.31840HepG2RTF1
LAMTOR2ENSG00000116586.7345.20180226.763500.606204.698303.89610HepG2SAFB2
LAMTOR2ENSG00000116586.7341.26240205.665900.730502.561801.65580HepG2SERBP1
LAMTOR2ENSG00000116586.7471.98890264.433500.8357010.529509.40660HepG2SMN1
LAMTOR2ENSG00000116586.7543.78920386.446800.492704.199803.64690HepG2SRSF1
LAMTOR2ENSG00000116586.7621.29040512.508200.277601.826101.30160HepG2SUCLG1
LAMTOR2ENSG00000116586.7476.85310304.670500.646203.359202.62200HepG2SUPV3L1
LAMTOR2ENSG00000116586.7447.82020247.390800.856008.508207.71830HepG2TIAL1
LAMTOR2ENSG00000116586.7334.53890249.646900.422202.548602.00290HepG2TRIM56
LAMTOR2ENSG00000116586.7379.63030267.869600.503003.399302.74690HepG2UTP3
LAMTOR2ENSG00000116586.7413.65780233.492400.825005.094603.68520HepG2XRCC6
LAMTOR2ENSG00000116586.7484.16170299.915300.690804.109803.23420HepG2XRN2
LAMTOR2ENSG00000116586.7435.86920305.144900.514304.521403.86640HepG2ZNF622
LAMTOR2ENSG00000116586.7773.56970508.373300.605507.862606.97500K562AGGF1
LAMTOR2ENSG00000116586.7831.47080558.651200.573605.752504.21110K562AKAP8
LAMTOR2ENSG00000116586.7781.43230528.991800.562805.289504.37150K562AKAP8L
LAMTOR2ENSG00000116586.7718.59420555.051700.372503.258302.26130K562ATP5C1
LAMTOR2ENSG00000116586.7590.70100488.118100.275101.874101.31830K562DDX47
LAMTOR2ENSG00000116586.7590.17760470.831800.325802.341201.67050K562EIF2S2
LAMTOR2ENSG00000116586.7206.10010305.93020-0.569902.757501.63380K562FKBP4
LAMTOR2ENSG00000116586.737.00190194.98070-2.3977017.5410015.36250K562G3BP2
LAMTOR2ENSG00000116586.7791.11810627.483700.334202.245801.56150K562GRSF1
LAMTOR2ENSG00000116586.7266.33620352.47770-0.404301.878401.37480K562HNRNPC
LAMTOR2ENSG00000116586.7203.36970314.73900-0.630103.531502.23140K562HNRNPF
LAMTOR2ENSG00000116586.7156.90200333.50660-1.0879010.453207.29750K562HNRNPH1
LAMTOR2ENSG00000116586.7184.22180334.41350-0.860205.680403.84460K562HNRNPK
LAMTOR2ENSG00000116586.7380.23550211.169200.848403.891302.77540K562HNRNPM
LAMTOR2ENSG00000116586.7363.85570494.21950-0.441803.243802.27990K562HNRNPU
LAMTOR2ENSG00000116586.7540.29050348.010000.634504.924403.87240K562HSPD1
LAMTOR2ENSG00000116586.7811.20450561.370300.531005.237604.02940K562KIF1C
LAMTOR2ENSG00000116586.7450.77270291.447900.629103.746502.76940K562PPIG
LAMTOR2ENSG00000116586.7434.68600316.026500.459802.773901.86890K562PSIP1
LAMTOR2ENSG00000116586.7843.95710524.569400.685906.640505.84120K562PUS1
LAMTOR2ENSG00000116586.7734.99230511.151400.523905.429804.62380K562RBM15
LAMTOR2ENSG00000116586.769.76720191.39660-1.455905.264402.99040K562TAF15
LAMTOR2ENSG00000116586.7472.49870327.202500.530003.783002.80380K562TIA1
LAMTOR2ENSG00000116586.786.30020195.19580-1.177507.743706.39260K562U2AF2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for LAMTOR2 is not available on ENCORE database.





4 RBPs can affect the splicing of LAMTOR2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SELAMTOR2ENSG00000116586.7chr1+1560253611560254661560250531560252161560277681560278580.142000.000680.01486includedHepG2U2AF1
SELAMTOR2ENSG00000116586.7chr1+156027768156027858156025361156025466156028105156028301-0.200000.002930.04962excludedHepG2U2AF1
SELAMTOR2ENSG00000116586.7chr1+156027768156027858156025361156025466156028105156028301-0.079000.000590.00786excludedK562AQR
SELAMTOR2ENSG00000116586.7chr1+1560277681560278581560250531560252161560281051560283010.103000.000950.04395includedHepG2SFPQ
SELAMTOR2ENSG00000116586.7chr1+156027768156027858156025053156025216156028105156028301-0.156000.000090.00311excludedK562U2AF1
SELAMTOR2ENSG00000116586.7chr1+1560277681560278581560250531560252161560281051560283010.103000.000700.07295includedHepG2RBFOX2
A5SSLAMTOR2ENSG00000116586.7chr1+1560246401560248171560246401560247481560250531560252160.057000.000000.00000longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for LAMTOR2 is not avaliable on ENCORE database.