DHX38

General Information

Gene Name : DHX38
Gene ID : ENSG00000140829.11
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: DHX38)

Not Available

Antibody Validation

Thermo Fisher: A300-858A

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	DHX38	ENSG00000140829.11	24.64	27.41	26.02	ENCSR000AEF
HepG2	DHX38	ENSG00000140829.11	96.64	51.49	74.06	ENCSR985KAT
K562	DHX38	ENSG00000140829.11	32.76	27.44	30.10	ENCSR000AEO

Assays

1 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Linked Antibody	Controls	Method	Note
eCLIP	eCLIP: 4202	ENCSR678OKJ	DHX38	HepG2	Released	ENCAB630HFE	ENCSR038SNS

eCLIP

RBP	Exp_UID	Cell_Line	ENCODE_ACCESSION	Control_ENCODE_ACCESSION	ENCODE_Antibody_ID	Antibody	Lot_num	Status	Project
DHX38	4202	HepG2	ENCSR678OKJ	ENCSR038SNS	ENCAB630HFE	A300-858A	1	Released	ENCODE4

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
PRP16	ENCAB630HFE	A300-858A	1			Released, ENCODE4

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project	Note
DHX38	K562	CRISPR			BGKcLV21-19,BGKcLV21-20	BGKcLV21-1,BGKcLV21-2		NotSatisfied	ENCODE4

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
PRP16	Product_ID: A300-858A Lot_ID: 1 Source: Thermo Fisher Target Name: PRP16-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for DHX38 is not avaliable on ENCORE database.

Proteins bound to RNA

DHX38 RNA is bound by 27 proteins.

CanvasJS.com

eCLIP assay for DHX38 is not avaliable on ENCORE database.

27 proteins are bound to DHX38 RNA:

Show entries

Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr16	72137500	72137566	+	CDS,intron-Distal,intron-Proximal	4.24200	17.27651	HepG2	GRWD1
chr16	72127859	72127928	+	5'-UTR,intron-Distal,intron-Proximal	4.10979	16.57604	HepG2	GRWD1
chr16	72137500	72137575	+	CDS,intron-Distal,intron-Proximal	3.91097	16.44414	K562	UCHL5
chr16	72137043	72137111	+	CDS,intron-Distal,intron-Proximal	4.40374	16.42772	K562	UCHL5
chr16	72144900	72144973	+	3'-UTR,CDS,intron-Distal,intron-Proximal	3.67689	15.00826	HepG2	PPIG
chr16	72131686	72131754	+	intron-Distal,intron-Proximal	5.26169	14.81877	K562	AQR
chr16	72139130	72139188	+	CDS,intron-Distal,intron-Proximal	3.24227	13.74429	HepG2	PPIG
chr16	72138024	72138089	+	CDS,intron-Distal,intron-Proximal	3.74003	13.56463	HepG2	PRPF8
chr16	72138054	72138160	+	intron-Distal,intron-Proximal	4.73807	13.15564	K562	HNRNPM
chr16	72130803	72130913	+	CDS,intron-Distal,intron-Proximal	3.28668	12.56573	K562	ZNF622
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 152 entries

eCLIP assay for DHX38 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for DHX38 is not available on ENCORE database.
62 RBPs can affect the levels of DHX38.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for DHX38 is not available on ENCORE database.

62 RBPs can affect the gene expression of DHX38 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
DHX38	ENSG00000140829.7	2022.40800	3770.08740	-0.89850	29.95240	28.61190	HepG2	RBM22
DHX38	ENSG00000140829.7	2418.95690	1140.22200	1.08500	21.66660	19.09950	K562	SF3B4
DHX38	ENSG00000140829.7	3324.56710	1680.23610	0.98440	18.75390	16.12720	K562	EFTUD2
DHX38	ENSG00000140829.7	4296.38960	2639.74980	0.70260	11.75930	10.68740	K562	PUS1
DHX38	ENSG00000140829.7	3678.26490	2572.27390	0.51590	10.67310	9.53390	K562	RBM15
DHX38	ENSG00000140829.7	1662.68890	2701.21290	-0.70010	10.35550	9.10960	HepG2	CPSF6
DHX38	ENSG00000140829.7	2717.86560	1635.07270	0.73300	10.54670	9.07500	K562	PRPF8
DHX38	ENSG00000140829.7	3510.92180	2558.29410	0.45660	9.67700	8.69770	K562	AGGF1
DHX38	ENSG00000140829.7	2294.78270	1442.94450	0.66920	10.21840	8.28670	K562	PCBP2
DHX38	ENSG00000140829.7	1063.30650	1977.22800	-0.89490	10.17480	8.17480	HepG2	AGO1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 68 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for DHX38 is not available on ENCORE database.

8 RBPs can affect the splicing of DHX38 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
A3SS	DHX38	ENSG00000140829.7	chr16	+	72131512	72131680	72131575	72131680	72130825	72130908	0.11800	0.00000	0.00001	longer	K562	U2AF2
A3SS	DHX38	ENSG00000140829.7	chr16	+	72139882	72140003	72139903	72140003	72139344	72139523	0.12200	0.00000	0.00000	longer	K562	AQR
RI	DHX38	ENSG00000140829.7	chr16	+	72132825	72133179	72132825	72132944	72133102	72133179	0.09400	0.00000	0.00003	included	HepG2	U2AF2
RI	DHX38	ENSG00000140829.7	chr16	+	72132825	72133179	72132825	72132944	72133102	72133179	0.07100	0.00000	0.00000	included	K562	AQR
SE	DHX38	ENSG00000140829.7	chr16	+	72131575	72131680	72130720	72130908	72132543	72132691	-0.06100	0.00001	0.00262	excluded	HepG2	SRSF7
RI	DHX38	ENSG00000140829.7	chr16	+	72132825	72133179	72132825	72132944	72133102	72133179	0.06900	0.00001	0.00012	included	HepG2	U2AF1
A5SS	DHX38	ENSG00000140829.7	chr16	+	72139903	72140016	72139903	72140003	72141238	72141447	-0.16800	0.00007	0.00725	shorter	HepG2	HNRNPK
A3SS	DHX38	ENSG00000140829.7	chr16	+	72131512	72131680	72131575	72131680	72130825	72130908	0.07000	0.00008	0.00529	longer	K562	U2AF1
SE	DHX38	ENSG00000140829.7	chr16	+	72131575	72131680	72130743	72130908	72132543	72132691	-0.05700	0.00019	0.00496	excluded	HepG2	U2AF1
SE	DHX38	ENSG00000140829.7	chr16	+	72131575	72131680	72130825	72130908	72132543	72132691	-0.08000	0.00023	0.01194	excluded	K562	TARDBP

Showing 1 to 10 of 13 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

DHX38

General Information

Functions

Localization

Domains (AlphaFold: DHX38)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for DHX38 is not avaliable on ENCORE database.

27 proteins are bound to DHX38 RNA:

eCLIP assay for DHX38 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for DHX38 is not available on ENCORE database.

62 RBPs can affect the gene expression of DHX38 :

The Knockdown/knockout RNA-Seq assay for DHX38 is not available on ENCORE database.

8 RBPs can affect the splicing of DHX38 :

The Knockdown/knockout RNA-Seq assay for DHX38 is not avaliable on ENCORE database.