COPS5

General Information

Gene Name       : COPS5
Gene ID             : ENSG00000121022.13
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: COPS5)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878COPS5ENSG00000121022.1331.9135.5533.73ENCSR000AEF
HepG2COPS5ENSG00000121022.1340.2650.8145.53ENCSR985KAT
K562COPS5ENSG00000121022.1376.6665.0970.88ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for COPS5 is not avaliable on ENCORE database.



Proteins bound to RNA
  • COPS5 RNA is bound by 14 proteins.  







eCLIP assay for COPS5 is not avaliable on ENCORE database.





14 proteins are bound to COPS5 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr86796347467963577-3'-UTR,CDS,intron-Distal,intron-Proximal4.114743.74511K562IGF2BP1
chr86797149367971656-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.2156610.90260HepG2BCLAF1
chr86796351567963577-3'-UTR,CDS,intron-Distal,intron-Proximal3.528995.32768K562YBX3
chr86795542467955460-3'-UTR,intron-Distal4.910348.66641K562YBX3
chr86796345667963580-3'-UTR,CDS,intron-Distal,intron-Proximal3.286055.29017HepG2BCLAF1
chr86795547967955552-3'-UTR,CDS,intron-Distal4.5310813.27358K562YBX3
chr86797155867971674-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.523387.03584HepG2GRWD1
chr86795546067955479-3'-UTR,CDS,intron-Distal4.846897.41523K562YBX3
chr86796345267963571-3'-UTR,CDS,intron-Distal,intron-Proximal4.241284.94878HepG2GRWD1
chr86797147767971558-5'-UTR,CDS,intron-Distal,intron-Proximal3.607955.10069HepG2GRWD1
chr86797427667974339-5'-UTR,intron-Distal,intron-Proximal3.728479.88402K562DDX3X
chr86797040967970447-5'-UTR,CDS,intron-Distal,intron-Proximal3.872824.09885HepG2BCLAF1
chr86797420767974284-5'-UTR,CDS,intron-Distal,intron-Proximal4.193853.81597K562RBM15
chr86796879367968840-5'-UTR,CDS,intron-Distal,intron-Proximal4.893455.17531K562DDX55
chr86796961467969662-5'-UTR,CDS,intron-Distal,intron-Proximal4.606954.59553K562DDX55
chr86797144567971493-5'-UTR,CDS,intron-Distal,intron-Proximal4.511108.41475HepG2BCLAF1
chr86797408567974266-5'-UTR,CDS,intron-Distal,intron-Proximal3.074973.94389K562ZNF800
chr86797410167974292-5'-UTR,CDS,intron-Distal,intron-Proximal3.630563.07278HepG2UCHL5
chr86797403367974093-CDS,intron-Distal,intron-Proximal3.521533.09957HepG2AQR
chr86797407967974165-CDS,intron-Distal,intron-Proximal3.194754.24005HepG2BCLAF1
chr86797062867970720-intron-Distal4.305263.66668K562KHSRP
chr86796273067962781-intron-Distal5.7291112.92204K562AGGF1
chr86796971667969819-intron-Distal,intron-Proximal3.173743.28806K562KHSRP
chr86796272767962849-intron-Distal4.3779513.41935HepG2HNRNPL
chr86796278167962863-intron-Distal3.6086611.14072K562AGGF1
chr86796277167962872-intron-Distal5.388329.55090K562HNRNPL
chr86796270567962861-intron-Distal3.685663.77708K562GTF2F1
chr86797389067974030-intron-Distal,intron-Proximal3.556064.50290K562GTF2F1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for COPS5 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for COPS5 is not available on ENCORE database.

  • 60 RBPs can affect the levels of COPS5.  








The Knockdown/knockout RNA-Seq assay for COPS5 is not available on ENCORE database.





60 RBPs can affect the gene expression of COPS5 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
COPS5ENSG00000121022.9777.40380957.46490-0.300603.036902.40490HepG2ACO1
COPS5ENSG00000121022.9629.23170483.558700.379802.345101.78850HepG2BOP1
COPS5ENSG00000121022.92048.882801485.845100.463504.037903.29350HepG2DDX3X
COPS5ENSG00000121022.9525.58110678.24090-0.367903.610202.88350HepG2DNAJC2
COPS5ENSG00000121022.91845.171201591.011800.213702.245001.69410HepG2ETF1
COPS5ENSG00000121022.91080.825201360.35640-0.331903.675202.62240HepG2HNRNPA2B1
COPS5ENSG00000121022.9966.951701284.72240-0.409903.245602.48990HepG2HNRNPK
COPS5ENSG00000121022.91025.894101348.30760-0.394303.766402.98710HepG2HNRNPL
COPS5ENSG00000121022.9629.46640779.70930-0.308803.320402.52340HepG2ILF2
COPS5ENSG00000121022.9962.783901297.50580-0.430502.474601.53540HepG2KHSRP
COPS5ENSG00000121022.9706.374601376.12060-0.9621011.6164010.38820HepG2MATR3
COPS5ENSG00000121022.91000.203001467.74360-0.553308.028406.75010HepG2NOL12
COPS5ENSG00000121022.91138.140201339.08380-0.234601.827301.31700HepG2PCBP1
COPS5ENSG00000121022.9837.32930646.171100.373802.204101.48080HepG2PRPF8
COPS5ENSG00000121022.91097.412201362.61140-0.312303.163002.58580HepG2PTBP1
COPS5ENSG00000121022.91130.409401487.35910-0.395906.727905.88730HepG2PUM1
COPS5ENSG00000121022.91133.501401486.25950-0.390904.122403.31110HepG2PUM2
COPS5ENSG00000121022.91168.257701475.64890-0.337003.357302.67820HepG2QKI
COPS5ENSG00000121022.9406.13150795.43620-0.969806.263805.22620HepG2RAVER1
COPS5ENSG00000121022.91129.496501516.41950-0.425005.936605.19290HepG2NELFE
COPS5ENSG00000121022.91110.884801412.40440-0.346404.158903.42390HepG2RECQL
COPS5ENSG00000121022.9374.05670506.36080-0.436902.827402.20690HepG2RPS19
COPS5ENSG00000121022.9853.39510639.194900.416902.429701.68870HepG2RRP9
COPS5ENSG00000121022.9562.12010679.76840-0.274202.114501.53820HepG2SAFB2
COPS5ENSG00000121022.91075.53940794.420300.437002.583401.93110HepG2SF3A3
COPS5ENSG00000121022.9605.51430475.374900.349001.908201.31490HepG2SF3B1
COPS5ENSG00000121022.91172.576701418.57620-0.274802.782402.18900HepG2SF3B4
COPS5ENSG00000121022.9644.66670792.71450-0.298202.789302.14370HepG2SMN1
COPS5ENSG00000121022.91927.485801501.974300.359806.213705.54570HepG2SRFBP1
COPS5ENSG00000121022.91003.938801383.41540-0.462606.974506.04420HepG2SRSF5
COPS5ENSG00000121022.91634.011801304.094700.325304.530303.90600HepG2SSB
COPS5ENSG00000121022.91336.128901573.30260-0.235702.577201.97240HepG2SUCLG1
COPS5ENSG00000121022.91096.181401331.01600-0.280002.587602.04390HepG2TAF15
COPS5ENSG00000121022.9585.65540748.34560-0.353703.280202.67790HepG2TRIM56
COPS5ENSG00000121022.91028.949901368.85780-0.411803.990402.91770HepG2TUFM
COPS5ENSG00000121022.9890.93600607.128000.553204.553203.75810HepG2U2AF1
COPS5ENSG00000121022.9642.07330522.657600.296802.349901.72430HepG2ZC3H8
COPS5ENSG00000121022.92196.234603223.58070-0.553607.192106.31680K562AQR
COPS5ENSG00000121022.91477.835801860.11190-0.331904.802603.51760K562BCLAF1
COPS5ENSG00000121022.9415.06470662.75880-0.675106.300104.53950K562CCAR1
COPS5ENSG00000121022.91103.559001411.17210-0.354703.897802.61470K562CSTF2
COPS5ENSG00000121022.92545.915301957.401900.379105.454604.58490K562DDX47
COPS5ENSG00000121022.9537.37690741.90160-0.465303.389201.90340K562DHX30
COPS5ENSG00000121022.91773.348401474.061600.266602.489901.73420K562EIF3G
COPS5ENSG00000121022.91087.318801401.69600-0.366403.239601.97070K562EIF4B
COPS5ENSG00000121022.9879.247801185.24070-0.430803.364401.95010K562EXOSC5
COPS5ENSG00000121022.91877.490201618.663900.213902.080901.54210K562FXR1
COPS5ENSG00000121022.91595.721101986.02750-0.315703.083301.94870K562HNRNPA1
COPS5ENSG00000121022.91535.701601121.835000.452903.450802.40110K562HNRNPM
COPS5ENSG00000121022.92327.190801848.794900.331902.876902.06610K562HSPD1
COPS5ENSG00000121022.91704.231102068.99560-0.279802.450401.58690K562MATR3
COPS5ENSG00000121022.91027.409201460.17200-0.507108.561707.21350K562MTPAP
COPS5ENSG00000121022.91250.268101622.29300-0.375806.861105.75870K562NSUN2
COPS5ENSG00000121022.91116.705801507.62750-0.433003.052602.17940K562PCBP3
COPS5ENSG00000121022.9893.632201156.46340-0.372002.205701.49110K562POLR2G
COPS5ENSG00000121022.92213.656301474.935500.585707.235406.02520K562PRPF8
COPS5ENSG00000121022.93172.566903937.21160-0.311504.068802.89890K562PUM2
COPS5ENSG00000121022.92734.540101892.130900.531205.964005.20460K562PUS1
COPS5ENSG00000121022.9714.55280921.53090-0.367002.797001.80110K562RCC2
COPS5ENSG00000121022.91959.524101502.557600.383002.878102.04370K562RPS19
COPS5ENSG00000121022.9733.531901032.10310-0.492704.011202.82800K562TRIM56
COPS5ENSG00000121022.91190.210501511.59120-0.344902.298801.37870K562UCHL5
COPS5ENSG00000121022.91288.440901720.15870-0.416906.766805.69840K562UPF1
COPS5ENSG00000121022.91891.487501530.657400.305304.481903.42310K562WDR43
COPS5ENSG00000121022.91085.941201538.98280-0.503004.488402.81180K562XRN2
COPS5ENSG00000121022.92763.453903631.60060-0.394104.421503.29010K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for COPS5 is not available on ENCORE database.





23 RBPs can affect the splicing of COPS5 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECOPS5ENSG00000121022.9chr8-6795991967960094679580466795819567963464679635760.090000.000000.00016includedHepG2HNRNPK
SECOPS5ENSG00000121022.9chr8-6795991967960094679580466795819567963464679635760.072000.000010.00208includedHepG2QKI
SECOPS5ENSG00000121022.9chr8-679599196796009467958046679581956796346467963576-0.069000.008600.08075excludedHepG2U2AF2
SECOPS5ENSG00000121022.9chr8-679740806797425967971445679716806797434067974415-0.374000.000000.00000excludedK562AQR
SECOPS5ENSG00000121022.9chr8-6795991967960094679580466795819567963464679635760.261000.000090.01040includedHepG2FTO
SECOPS5ENSG00000121022.9chr8-6795991967960094679580466795819567963464679635760.059000.001350.05264includedHepG2MATR3
SECOPS5ENSG00000121022.9chr8-679599196796009467958046679581956796346467963576-0.052000.000050.01208excludedK562HNRNPM
SECOPS5ENSG00000121022.9chr8-679740806797425967971445679716806797434067974388-0.364000.000650.01799excludedHepG2SRSF1
SECOPS5ENSG00000121022.9chr8-6795991967960094679580466795819567963464679635760.057000.000060.04827includedK562TBRG4
SECOPS5ENSG00000121022.9chr8-6795991967960094679580466795819567963464679635760.070000.000010.00145includedHepG2SF3B4
SECOPS5ENSG00000121022.9chr8-679740806797425967971445679716806797434067974415-0.354000.001670.06932excludedHepG2SF3B4
SECOPS5ENSG00000121022.9chr8-6795991967960094679580466795819567963464679635760.051000.000760.07321includedHepG2TAF15
SECOPS5ENSG00000121022.9chr8-6795991967960094679580466795819567963464679635760.091000.000040.01301includedHepG2DDX55
SECOPS5ENSG00000121022.9chr8-6795991967960094679580466795819567963464679635760.108000.000010.00537includedHepG2FUBP3
SECOPS5ENSG00000121022.9chr8-6797352667973657679714456797168067974088679742640.068000.000000.00002includedK562HNRNPC
A3SSCOPS5ENSG00000121022.9chr8-6795804467958220679580446795819567963464679635760.059000.000000.00000longerK562AQR
RICOPS5ENSG00000121022.9chr8-6797144567974259679714456797168067974080679742590.446000.001390.01181includedHepG2U2AF2
RICOPS5ENSG00000121022.9chr8-6795531667958195679553166795555267958046679581950.062000.000030.00198includedHepG2TIA1
RICOPS5ENSG00000121022.9chr8-6795531667958195679553166795555267958046679581950.104000.002380.02818includedK562AGGF1
RICOPS5ENSG00000121022.9chr8-6797144567974259679714456797168067974080679742590.598000.005730.08516includedHepG2IGF2BP3
RICOPS5ENSG00000121022.9chr8-6795531667958195679553166795555267958046679581950.067000.000140.00530includedHepG2IGF2BP3
RICOPS5ENSG00000121022.9chr8-6795531667958195679553166795555267958046679581950.068000.000010.00033includedHepG2PCBP1
RICOPS5ENSG00000121022.9chr8-6795531667958195679553166795555267958046679581950.130000.000000.00000includedHepG2QKI
RICOPS5ENSG00000121022.9chr8-6795531667958195679553166795555267958046679581950.092000.000000.00001includedHepG2TAF15
RICOPS5ENSG00000121022.9chr8-6795531667958195679553166795555267958046679581950.060000.000350.00900includedHepG2G3BP1
RICOPS5ENSG00000121022.9chr8-679553166795819567955316679555526795804667958195-0.051000.000010.00158excludedK562EIF3G
RICOPS5ENSG00000121022.9chr8-6795531667958195679553166795555267958046679581950.065000.000610.01684includedHepG2KHSRP
RICOPS5ENSG00000121022.9chr8-6795531667958195679553166795555267958046679581950.242000.000020.00376includedK562SBDS
RICOPS5ENSG00000121022.9chr8-6795531667958195679553166795555267958046679581950.102000.000000.00000includedHepG2SF3B4
RICOPS5ENSG00000121022.9chr8-6795531667958195679553166795555267958046679581950.111000.000000.00001includedHepG2HNRNPK
RICOPS5ENSG00000121022.9chr8-6795531667958195679553166795555267958046679581950.076000.000000.00007includedHepG2PTBP1
RICOPS5ENSG00000121022.9chr8-6797144567974259679714456797168067974080679742590.288000.004390.02555includedK562AQR
RICOPS5ENSG00000121022.9chr8-6795531667958195679553166795555267958046679581950.109000.000000.00000includedK562AQR
RICOPS5ENSG00000121022.9chr8-679553166795819567955316679555526795804667958195-0.066000.000000.00000excludedK562PTBP1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for COPS5 is not avaliable on ENCORE database.