APAF1

General Information

Gene Name : APAF1
Gene ID : ENSG00000120868.13
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: APAF1)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	APAF1	ENSG00000120868.13	16.90	11.09	13.99	ENCSR000AEF
HepG2	APAF1	ENSG00000120868.13	4.89	8.09	6.49	ENCSR985KAT
K562	APAF1	ENSG00000120868.13	5.90	6.65	6.28	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for APAF1 is not avaliable on ENCORE database.

Proteins bound to RNA

APAF1 RNA is bound by 18 proteins.

CanvasJS.com

eCLIP assay for APAF1 is not avaliable on ENCORE database.

18 proteins are bound to APAF1 RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr12	99080644	99080648	+	CDS,intron-Distal	8.45984	83.48876	K562	NSUN2
chr12	99080648	99080651	+	CDS,intron-Distal	8.45984	83.48876	K562	NSUN2
chr12	99080633	99080644	+	CDS,intron-Distal	7.45984	81.64177	K562	NSUN2
chr12	99093185	99093190	+	CDS,intron-Distal,intron-Proximal	8.41553	80.91672	K562	NSUN2
chr12	99071273	99071323	+	CDS,intron-Distal	5.91214	16.18483	K562	LIN28B
chr12	99073228	99073312	+	intron-Distal	6.63968	14.52138	K562	LSM11
chr12	99128313	99128400	+	3'-UTR	5.84166	13.40947	K562	UPF1
chr12	99127968	99128053	+	3'-UTR	4.10420	11.97167	K562	PTBP1
chr12	99063623	99063746	+	intron-Distal	5.38560	9.42242	HepG2	PCBP2
chr12	99129086	99129157	+	3'-UTR	3.75167	7.06274	K562	PUM2
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 36 entries

eCLIP assay for APAF1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for APAF1 is not available on ENCORE database.
115 RBPs can affect the levels of APAF1.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for APAF1 is not available on ENCORE database.

115 RBPs can affect the gene expression of APAF1 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
APAF1	ENSG00000120868.9	317.72280	941.00920	-1.56640	47.27410	45.02780	HepG2	HNRNPU
APAF1	ENSG00000120868.9	661.04070	1788.84460	-1.43620	32.88670	29.78400	K562	TARDBP
APAF1	ENSG00000120868.9	668.69780	1446.31860	-1.11300	30.47130	28.60450	K562	FXR1
APAF1	ENSG00000120868.9	329.09980	810.46990	-1.30020	29.25820	27.62740	HepG2	UTP3
APAF1	ENSG00000120868.9	619.15270	1083.43750	-0.80720	18.29610	16.70660	HepG2	HNRNPL
APAF1	ENSG00000120868.9	504.85370	922.54360	-0.86980	17.24490	15.99620	HepG2	TRIM56
APAF1	ENSG00000120868.9	512.79490	1019.92830	-0.99200	15.79950	13.95830	K562	GRSF1
APAF1	ENSG00000120868.9	160.17270	451.86490	-1.49630	14.79250	13.07030	HepG2	UCHL5
APAF1	ENSG00000120868.9	496.27640	836.12340	-0.75260	14.25840	12.89330	HepG2	DNAJC2
APAF1	ENSG00000120868.9	1529.88450	950.71310	0.68620	12.64570	11.70000	HepG2	RBM22
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 137 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for APAF1 is not available on ENCORE database.

9 RBPs can affect the splicing of APAF1 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	APAF1	ENSG00000120868.9	chr12	+	99097148	99097277	99093185	99093347	99100262	99100388	0.46400	0.00000	0.00000	included	K562	SRSF1
SE	APAF1	ENSG00000120868.9	chr12	+	99097148	99097277	99093185	99093347	99100262	99100476	-0.24700	0.00000	0.00000	excluded	K562	AKAP8L
SE	APAF1	ENSG00000120868.9	chr12	+	99097148	99097277	99093185	99093347	99100262	99100388	-0.26400	0.00000	0.00000	excluded	K562	PUS1
SE	APAF1	ENSG00000120868.9	chr12	+	99097148	99097277	99093185	99093347	99100262	99100388	-0.24200	0.00000	0.00000	excluded	K562	RBM15
SE	APAF1	ENSG00000120868.9	chr12	+	99097148	99097277	99093185	99093347	99100262	99100388	-0.26300	0.00000	0.00000	excluded	K562	AGGF1
SE	APAF1	ENSG00000120868.9	chr12	+	99097148	99097277	99093185	99093347	99100262	99100388	0.20300	0.00017	0.00986	included	K562	PTBP1
SE	APAF1	ENSG00000120868.9	chr12	+	99097148	99097277	99093185	99093347	99100262	99100388	-0.15100	0.00165	0.04948	excluded	K562	UTP18
SE	APAF1	ENSG00000120868.9	chr12	+	99097148	99097277	99093185	99093347	99100262	99100388	-0.17200	0.00214	0.03690	excluded	K562	U2AF2
SE	APAF1	ENSG00000120868.9	chr12	+	99097148	99097277	99093273	99093347	99100262	99100388	0.27200	0.00234	0.04970	included	HepG2	SRSF1
SE	APAF1	ENSG00000120868.9	chr12	+	99097148	99097277	99093185	99093347	99100262	99100388	-0.14700	0.00425	0.07172	excluded	K562	U2AF1

Showing 1 to 10 of 10 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

APAF1

General Information

Functions

Localization

Domains (AlphaFold: APAF1)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for APAF1 is not avaliable on ENCORE database.

18 proteins are bound to APAF1 RNA:

eCLIP assay for APAF1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for APAF1 is not available on ENCORE database.

115 RBPs can affect the gene expression of APAF1 :

The Knockdown/knockout RNA-Seq assay for APAF1 is not available on ENCORE database.

9 RBPs can affect the splicing of APAF1 :

The Knockdown/knockout RNA-Seq assay for APAF1 is not avaliable on ENCORE database.