ZXDC

General Information

Gene Name       : ZXDC
Gene ID             : ENSG00000070476.14
Essential Gene : No

Functions

Localization

Domains (AlphaFold: ZXDC)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878ZXDCENSG00000070476.143.636.034.83ENCSR000AEF
HepG2ZXDCENSG00000070476.1414.6312.5813.61ENCSR985KAT
K562ZXDCENSG00000070476.146.225.025.62ENCSR000AEO

Assays

1 Released experiments are available on ENCORE database.

Assay TypeExp_NameENCODE IDTarget labelBiosampleStatusLinked AntibodyControlsMethodNote
knockdown followed by RNA-seq ZXDC-BGRSLV08-RS293ZXDCRibo-STAMP-293TReleased   shRNAKD% = ,






  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
ZXDCRibo-STAMP-293TshRNABGRSLV08-59,BGRSLV08-60BGRSLV08-1,BGRSLV08-2NotSatisfiedENCORE2
ZXDCRibo-STAMP-293TshRNAZXDC-BGRSLV08-61,ZXDC-BGRSLV08-62NT-BGRSLV08-1,NT-BGRSLV08-2,ReleasedENCORE2


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for ZXDC is not avaliable on ENCORE database.



Proteins bound to RNA
  • ZXDC RNA is bound by 24 proteins.  







eCLIP assay for ZXDC is not avaliable on ENCORE database.





24 proteins are bound to ZXDC RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr3126180335126180410-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.156809.70941HepG2PRPF8
chr3126157286126157379-3'-UTR,CDS,intron-Distal3.650463.59805HepG2SF3B4
chr3126157248126157305-3'-UTR,CDS,intron-Distal3.584687.61685HepG2PPIG
chr3126158472126158519-3'-UTR,CDS,intron-Distal,intron-Proximal3.488706.46638HepG2PPIG
chr3126160559126160640-3'-UTR,CDS,intron-Distal,intron-Proximal3.6001511.43193HepG2PRPF8
chr3126158532126158583-3'-UTR,CDS,intron-Distal,intron-Proximal4.332857.64877HepG2U2AF2
chr3126160602126160708-3'-UTR,CDS,intron-Distal,intron-Proximal3.251743.95327HepG2PPIG
chr3126189735126189789-CDS,intron-Distal,intron-Proximal4.104444.96634HepG2PPIG
chr3126180982126181057-CDS,intron-Distal3.470994.71371HepG2GRWD1
chr3126180450126180519-CDS,intron-Distal3.120674.96088HepG2GRWD1
chr3126193747126193811-CDS,intron-Distal3.170226.60804HepG2PRPF8
chr3126178437126178525-CDS,intron-Distal,intron-Proximal4.3427827.92654HepG2PRPF8
chr3126184951126185017-CDS,intron-Distal,intron-Proximal3.378235.34140HepG2PRPF8
chr3126190818126190881-CDS,intron-Distal3.139043.41665HepG2GRWD1
chr3126178442126178507-CDS,intron-Distal,intron-Proximal3.206114.56058HepG2BCLAF1
chr3126190818126190875-CDS,intron-Distal3.584686.81103HepG2PPIG
chr3126190993126191042-CDS,intron-Distal,intron-Proximal3.083203.17233HepG2BCLAF1
chr3126189736126189848-CDS,intron-Distal,intron-Proximal3.142034.43324HepG2BCLAF1
chr3126178558126178635-CDS,intron-Distal,intron-Proximal4.725153.56713HepG2SF3B4
chr3126191003126191065-CDS,intron-Distal4.695875.86613HepG2PPIG
chr3126165450126165582-intron-Distal6.0544658.56456HepG2QKI
chr3126168795126168855-intron-Distal3.596359.07592HepG2HNRNPM
chr3126167784126167868-intron-Distal3.764244.31768HepG2KHSRP
chr3126175761126175841-intron-Distal3.336266.05036HepG2FKBP4
chr3126164817126164892-intron-Distal3.082493.31157HepG2KHSRP
chr3126160984126161060-intron-Distal4.473573.72398HepG2SFPQ
chr3126187346126187400-intron-Distal4.593615.16513HepG2HNRNPM
chr3126170425126170586-intron-Distal4.090763.41051HepG2SRSF1
chr3126167117126167176-intron-Distal4.656644.57471HepG2SFPQ
chr3126167188126167233-intron-Distal4.105584.03101HepG2FUS
chr3126176828126176876-intron-Distal3.960568.65817HepG2HNRNPM
chr3126170471126170597-intron-Distal3.065134.89942HepG2GRWD1
chr3126168351126168394-intron-Distal3.919643.27946HepG2HNRNPM
chr3126167762126167876-intron-Distal3.839986.34658K562NONO
chr3126160344126160444-intron-Distal3.171513.23948HepG2HNRNPK
chr3126176787126176812-intron-Distal3.350893.68481HepG2HNRNPM
chr3126188482126188539-intron-Distal4.684904.64592HepG2HNRNPM
chr3126170947126171045-intron-Distal3.330103.40562HepG2SRSF9
chr3126178685126178729-intron-Distal4.012664.61500HepG2HNRNPM
chr3126171290126171371-intron-Distal3.072583.92782HepG2KHSRP
chr3126167626126167669-intron-Distal3.166083.69530HepG2CSTF2T
chr3126187034126187099-intron-Distal4.425094.38558HepG2HNRNPM
chr3126176625126176694-intron-Distal3.359255.79450HepG2XPO5
chr3126166797126166881-intron-Distal3.756533.15220HepG2HNRNPU
chr3126159576126159643-intron-Distal4.088674.88931HepG2FAM120A
chr3126170993126171016-intron-Distal4.221013.82973HepG2HLTF
chr3126159573126159670-intron-Distal4.977557.45950HepG2PRPF4
chr3126167569126167609-intron-Distal3.780314.09469HepG2XPO5
chr3126171289126171357-intron-Distal3.211383.24890K562SAFB2
chr3126168753126168816-intron-Distal4.115763.97974HepG2RBFOX2
chr3126169063126169088-intron-Distal4.334684.64592HepG2HNRNPM
chr3126168552126168603-intron-Distal3.876133.53896K562NONO
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for ZXDC is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for ZXDC is not available on ENCORE database.

  • 45 RBPs can affect the levels of ZXDC.  








The Knockdown/knockout RNA-Seq assay for ZXDC is not available on ENCORE database.





45 RBPs can affect the gene expression of ZXDC :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
ZXDCENSG00000070476.10603.16120736.48350-0.288102.409801.83530HepG2ACO1
ZXDCENSG00000070476.10679.23100465.381500.545404.221303.01800HepG2ADAR
ZXDCENSG00000070476.10501.69890827.19790-0.721405.656104.92720HepG2AKAP1
ZXDCENSG00000070476.10513.94080736.36190-0.518806.669505.71880HepG2CKAP4
ZXDCENSG00000070476.101119.55350864.394200.373102.829901.52240HepG2DDX47
ZXDCENSG00000070476.10578.67990468.592900.304302.022801.41190HepG2DNAJC21
ZXDCENSG00000070476.101010.00710654.311600.626205.554604.73160HepG2EIF2S1
ZXDCENSG00000070476.101342.17770723.035400.8923010.244309.03320HepG2EIF4A3
ZXDCENSG00000070476.101412.603501131.261700.320303.743903.06190HepG2ETF1
ZXDCENSG00000070476.101038.20620718.623700.530704.408603.27330HepG2G3BP2
ZXDCENSG00000070476.10874.94060583.604000.584104.379203.58560HepG2GPKOW
ZXDCENSG00000070476.10934.27600703.154200.409904.778303.52870HepG2HDGF
ZXDCENSG00000070476.10716.52830550.581000.380003.168302.40450HepG2HNRNPF
ZXDCENSG00000070476.10740.16750556.946700.410202.515701.91120HepG2HNRNPLL
ZXDCENSG00000070476.10293.48390522.75470-0.8329010.611009.48700HepG2HNRNPU
ZXDCENSG00000070476.10787.81170542.159800.539005.146204.18980HepG2IGF2BP1
ZXDCENSG00000070476.10967.21370687.918300.491503.679202.90890HepG2IGF2BP2
ZXDCENSG00000070476.101118.83040729.937000.616005.493104.57790HepG2MAGOH
ZXDCENSG00000070476.10982.82390733.994900.421102.562501.95290HepG2MATR3
ZXDCENSG00000070476.10671.74140493.861100.443702.672401.93660HepG2NSUN2
ZXDCENSG00000070476.101024.94000652.081700.652303.573602.55490HepG2PABPC1
ZXDCENSG00000070476.101099.34890906.566700.278102.441601.81210HepG2PUM2
ZXDCENSG00000070476.101051.89470697.376300.592906.858505.83690HepG2RBM25
ZXDCENSG00000070476.10754.63350593.190200.347201.979301.39020HepG2RPLP0
ZXDCENSG00000070476.10234.71390416.42430-0.827204.750503.75210HepG2RRP9
ZXDCENSG00000070476.10695.69810540.946000.362902.923102.21080HepG2SRSF7
ZXDCENSG00000070476.10760.76580627.280900.278202.396201.87500HepG2SRSF9
ZXDCENSG00000070476.101326.95310927.202500.517108.771307.95820HepG2SSB
ZXDCENSG00000070476.10800.21800636.790900.329502.423601.63980HepG2TIA1
ZXDCENSG00000070476.10456.46130321.043100.507602.520401.79620HepG2UCHL5
ZXDCENSG00000070476.101016.44450853.051400.252702.151501.60980HepG2UTP3
ZXDCENSG00000070476.10446.37790646.14920-0.533602.842201.77160HepG2XRCC6
ZXDCENSG00000070476.101151.43550971.756700.244702.645002.10720HepG2ZNF622
ZXDCENSG00000070476.10408.48110659.77900-0.691708.174907.27000K562AGGF1
ZXDCENSG00000070476.10412.97290686.53130-0.733307.315906.20780K562AKAP8L
ZXDCENSG00000070476.10489.31470720.33910-0.557905.878804.48760K562ATP5C1
ZXDCENSG00000070476.10552.73060788.46770-0.512504.929903.31380K562CCDC124
ZXDCENSG00000070476.10567.16460774.10140-0.448803.262201.66650K562DDX19B
ZXDCENSG00000070476.10590.89490438.978900.428703.654002.91830K562DDX47
ZXDCENSG00000070476.10537.46610738.74840-0.458904.422103.27830K562DKC1
ZXDCENSG00000070476.10141.45340205.83880-0.541201.882101.31170K562G3BP2
ZXDCENSG00000070476.10303.24660415.62690-0.454803.073302.13460K562HNRNPU
ZXDCENSG00000070476.10431.82460728.57650-0.754607.524705.99980K562KIF1C
ZXDCENSG00000070476.10517.83550697.43090-0.429602.729001.66220K562MAK16
ZXDCENSG00000070476.10598.92580816.19040-0.446503.421102.39190K562MBNL1
ZXDCENSG00000070476.10335.24890572.09080-0.771005.016903.71170K562NAA15
ZXDCENSG00000070476.10319.60490680.84110-1.0910013.3607012.21190K562PUS1
ZXDCENSG00000070476.10371.59990663.38500-0.8361010.422509.29540K562RBM15
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for ZXDC is not available on ENCORE database.





2 RBPs can affect the splicing of ZXDC :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEZXDCENSG00000070476.10chr3-126184997126185168126180112126181063126189737126189868-0.249000.004620.04990excludedHepG2U2AF2
A3SSZXDCENSG00000070476.10chr3-1261897371261899561261897371261898681261908151261908940.210000.000000.00000longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for ZXDC is not avaliable on ENCORE database.