JAK1

General Information

Gene Name : JAK1
Gene ID : ENSG00000162434.11
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: JAK1)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	JAK1	ENSG00000162434.11	35.91	29.76	32.84	ENCSR000AEF
HepG2	JAK1	ENSG00000162434.11	25.59	32.60	29.09	ENCSR985KAT
K562	JAK1	ENSG00000162434.11	26.98	29.63	28.30	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for JAK1 is not avaliable on ENCORE database.

Proteins bound to RNA

JAK1 RNA is bound by 21 proteins.

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eCLIP assay for JAK1 is not avaliable on ENCORE database.

21 proteins are bound to JAK1 RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr1	65316432	65316544	-	CDS,intron-Distal,intron-Proximal	4.27721	11.57027	HepG2	PRPF8
chr1	65432079	65432152	-	5'-UTR,intron-Distal	4.11357	9.88902	HepG2	DDX3X
chr1	65348959	65349044	-	CDS,intron-Distal,intron-Proximal	5.50128	9.52979	K562	FXR2
chr1	65332706	65332797	-	CDS,intron-Distal	4.95766	9.07433	K562	YBX3
chr1	65335086	65335197	-	CDS,intron-Distal,intron-Proximal	3.77587	9.05957	K562	BUD13
chr1	65432024	65432079	-	5'-UTR,intron-Distal	4.72500	8.90399	HepG2	DDX3X
chr1	65299385	65299444	-	3'-UTR,intron-Distal	3.76807	6.56922	K562	IGF2BP1
chr1	65411055	65411225	-	intron-Distal	4.43103	5.91698	K562	KHSRP
chr1	65335008	65335084	-	CDS,intron-Distal	3.69162	5.80880	HepG2	GRWD1
chr1	65332691	65332780	-	CDS,intron-Distal	3.09887	5.66840	K562	ZNF622
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 45 entries

eCLIP assay for JAK1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for JAK1 is not available on ENCORE database.
108 RBPs can affect the levels of JAK1.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for JAK1 is not available on ENCORE database.

108 RBPs can affect the gene expression of JAK1 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
JAK1	ENSG00000162434.7	1609.59450	3087.61360	-0.93980	22.03420	19.78900	K562	GRSF1
JAK1	ENSG00000162434.7	863.18850	2564.47320	-1.57090	21.51440	19.42490	HepG2	CNOT7
JAK1	ENSG00000162434.7	3796.95220	2475.88200	0.61680	20.20700	19.17650	HepG2	SRSF1
JAK1	ENSG00000162434.7	4100.53710	2603.07620	0.65550	17.88440	16.80000	HepG2	RBM22
JAK1	ENSG00000162434.7	5277.89910	1892.47590	1.47960	17.97140	16.32910	HepG2	RAVER1
JAK1	ENSG00000162434.7	3005.63030	2014.29850	0.57730	16.70360	15.55250	HepG2	SRSF9
JAK1	ENSG00000162434.7	3066.38040	1693.02270	0.85680	16.89530	15.39330	HepG2	DDX21
JAK1	ENSG00000162434.7	3210.57330	1719.19460	0.90100	13.50560	12.19680	HepG2	SUPV3L1
JAK1	ENSG00000162434.7	2849.98240	1778.39230	0.68030	13.83580	12.02310	K562	U2AF2
JAK1	ENSG00000162434.7	3247.96380	1868.20520	0.79780	12.92560	11.53390	HepG2	U2AF1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 124 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for JAK1 is not available on ENCORE database.

1 RBPs can affect the splicing of JAK1 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
A3SS	JAK1	ENSG00000162434.7	chr1	-	65307133	65307333	65307133	65307284	65309746	65309917	0.09800	0.00000	0.00000	longer	K562	AQR
A3SS	JAK1	ENSG00000162434.7	chr1	-	65305285	65305499	65305285	65305478	65306927	65307022	0.14400	0.00000	0.00000	longer	K562	AQR
A3SS	JAK1	ENSG00000162434.7	chr1	-	65309778	65309963	65309778	65309898	65310436	65310572	0.09100	0.00000	0.00000	longer	K562	AQR
A3SS	JAK1	ENSG00000162434.7	chr1	-	65301078	65301320	65301078	65301189	65301780	65301931	0.05200	0.00069	0.00501	longer	K562	AQR
A3SS	JAK1	ENSG00000162434.7	chr1	-	65301780	65301931	65301780	65301898	65303614	65303787	0.09200	0.00208	0.01334	longer	K562	AQR

Showing 1 to 5 of 5 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

JAK1

General Information

Functions

Localization

Domains (AlphaFold: JAK1)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for JAK1 is not avaliable on ENCORE database.

21 proteins are bound to JAK1 RNA:

eCLIP assay for JAK1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for JAK1 is not available on ENCORE database.

108 RBPs can affect the gene expression of JAK1 :

The Knockdown/knockout RNA-Seq assay for JAK1 is not available on ENCORE database.

1 RBPs can affect the splicing of JAK1 :

The Knockdown/knockout RNA-Seq assay for JAK1 is not avaliable on ENCORE database.