FAM189B

General Information

Gene Name : FAM189B
Gene ID : ENSG00000160767.20
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: FAM189B)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	FAM189B	ENSG00000160767.20	2.03	4.36	3.20	ENCSR000AEF
HepG2	FAM189B	ENSG00000160767.20	15.75	6.96	11.36	ENCSR985KAT
K562	FAM189B	ENSG00000160767.20	15.80	7.94	11.87	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for FAM189B is not avaliable on ENCORE database.

Proteins bound to RNA

FAM189B RNA is bound by 9 proteins.

CanvasJS.com

eCLIP assay for FAM189B is not avaliable on ENCORE database.

9 proteins are bound to FAM189B RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr1	155225134	155225196	-	5'-UTR,intron-Distal,intron-Proximal	5.73553	15.44971	HepG2	DDX3X
chr1	155224884	155224983	-	5'-UTR,intron-Distal,intron-Proximal	3.72208	10.20469	HepG2	DDX3X
chr1	155220272	155220391	-	CDS,intron-Distal,intron-Proximal	5.28200	10.10883	K562	PCBP1
chr1	155220070	155220174	-	CDS,intron-Distal	4.83570	7.84681	K562	IGF2BP2
chr1	155225196	155225243	-	intron-Distal,intron-Proximal	4.11645	6.96497	HepG2	DDX3X
chr1	155224912	155225059	-	5'-UTR,intron-Distal,intron-Proximal	3.24600	6.40768	K562	GEMIN5
chr1	155221641	155221697	-	CDS,intron-Distal,intron-Proximal	3.27320	6.09506	K562	IGF2BP2
chr1	155217071	155217157	-	3'-UTR,intron-Distal,intron-Proximal	4.61707	6.09204	K562	YBX3
chr1	155221528	155221610	-	CDS,intron-Distal,intron-Proximal	3.86793	5.47443	HepG2	PCBP2
chr1	155220310	155220379	-	CDS,intron-Distal,intron-Proximal	4.38423	5.01757	K562	IGF2BP2
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 20 entries

eCLIP assay for FAM189B is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for FAM189B is not available on ENCORE database.
92 RBPs can affect the levels of FAM189B.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for FAM189B is not available on ENCORE database.

92 RBPs can affect the gene expression of FAM189B :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
FAM189B	ENSG00000160767.16	334.01280	1099.52880	-1.71890	55.18080	53.66870	HepG2	SRSF1
FAM189B	ENSG00000160767.16	1695.38970	576.54300	1.55600	38.23740	35.68140	HepG2	EIF4G2
FAM189B	ENSG00000160767.16	361.83330	894.56000	-1.30590	33.41770	31.91130	HepG2	SRSF9
FAM189B	ENSG00000160767.16	829.37920	390.63750	1.08610	23.64090	22.19060	HepG2	TRIM56
FAM189B	ENSG00000160767.16	601.19590	1126.04680	-0.90540	18.31270	17.15930	HepG2	NELFE
FAM189B	ENSG00000160767.16	1360.06740	691.50900	0.97580	18.96610	16.15920	K562	DDX3X
FAM189B	ENSG00000160767.16	620.14740	1095.74170	-0.82120	13.39210	12.16730	HepG2	QKI
FAM189B	ENSG00000160767.16	797.24370	1310.48120	-0.71700	13.57220	11.87450	K562	SF3A3
FAM189B	ENSG00000160767.16	320.93030	601.86430	-0.90720	12.61170	11.08220	HepG2	EIF4G1
FAM189B	ENSG00000160767.16	1520.00000	956.98700	0.66740	12.01060	10.77670	K562	RBM15
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 104 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for FAM189B is not available on ENCORE database.

16 RBPs can affect the splicing of FAM189B :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	FAM189B	ENSG00000160767.16	chr1	-	155223649	155223769			155223415	155223523	155224443	155225178	-0.38100	0.00000	0.00012	excluded	HepG2	U2AF2
SE	FAM189B	ENSG00000160767.16	chr1	-	155220066	155220612			155218195	155218264	155220885	155220955	-0.53700	0.00000	0.00000	excluded	HepG2	SRSF9
MXE	FAM189B	ENSG00000160767.16	chr1	-	155223649	155223769	155224190	155224326	155223415	155223523	155224443	155225178	-0.11600	0.00000	0.00011	2included	HepG2	RBM15
SE	FAM189B	ENSG00000160767.16	chr1	-	155224190	155224247			155223415	155223523	155224443	155224755	-0.35100	0.00001	0.00042	excluded	K562	U2AF1
SE	FAM189B	ENSG00000160767.16	chr1	-	155223649	155223769			155223415	155223523	155224443	155225178	-0.27000	0.00002	0.00273	excluded	HepG2	SRSF9
MXE	FAM189B	ENSG00000160767.16	chr1	-	155223649	155223769	155224190	155224326	155223415	155223523	155224443	155225178	-0.15100	0.00003	0.00161	2included	HepG2	HNRNPK
A3SS	FAM189B	ENSG00000160767.16	chr1	-	155220885	155221022			155220885	155220955	155221292	155221392	0.10300	0.00006	0.00057	longer	K562	AQR
SE	FAM189B	ENSG00000160767.16	chr1	-	155223649	155223769			155223415	155223523	155224443	155225178	0.22500	0.00007	0.01893	included	HepG2	RBM15
SE	FAM189B	ENSG00000160767.16	chr1	-	155224190	155224326			155223415	155223523	155224443	155224699	-0.18100	0.00010	0.00703	excluded	HepG2	MATR3
SE	FAM189B	ENSG00000160767.16	chr1	-	155224190	155224247			155223415	155223523	155224443	155224755	-0.29100	0.00010	0.07649	excluded	HepG2	YBX3

Showing 1 to 10 of 25 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

FAM189B

General Information

Functions

Localization

Domains (AlphaFold: FAM189B)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for FAM189B is not avaliable on ENCORE database.

9 proteins are bound to FAM189B RNA:

eCLIP assay for FAM189B is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for FAM189B is not available on ENCORE database.

92 RBPs can affect the gene expression of FAM189B :

The Knockdown/knockout RNA-Seq assay for FAM189B is not available on ENCORE database.

16 RBPs can affect the splicing of FAM189B :

The Knockdown/knockout RNA-Seq assay for FAM189B is not avaliable on ENCORE database.