APEH

General Information

Gene Name : APEH
Gene ID : ENSG00000164062.12
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: APEH)

Not Available

Antibody Validation

Bethyl Labs: A304-808A

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	APEH	ENSG00000164062.12	78.70	88.81	83.75	ENCSR000AEF
HepG2	APEH	ENSG00000164062.12	96.33	90.45	93.39	ENCSR985KAT
K562	APEH	ENSG00000164062.12	86.55	87.75	87.15	ENCSR000AEO

Assays

2 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Linked Antibody	Controls	Method	Note
knockdown followed by RNA-seq	APEH-BGKcLV26-K562	ENCSR785JUR	APEH	K562	Released		ENCSR900GQL	CRISPR	KD% = 82.4,88.3686745
knockdown followed by RNA-seq	APEH-BGHcLV27-HepG2	ENCSR828XJV	APEH	HepG2	Released		ENCSR650TTU	CRISPR	KD% = 85.9,87.2

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
APEH	ENCAB652JMJ	A304-808A	1			Released, ENCODE4	BGHcLV27-9, Released, ENCODE4	BGKcLV26-25, Released, ENCODE4

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project	Note
APEH	K562	CRISPR	ENCSR785JUR	ENCSR900GQL	APEH-BGKcLV26-25,APEH-BGKcLV26-26	NT-BGKcLV26-1,NT-BGKcLV26-2	82.4,88.3686745	Released	ENCODE4
APEH	HepG2	CRISPR	ENCSR828XJV	ENCSR650TTU	APEH-BGHcLV27-9,APEH-BGHcLV27-10	NT-BGHcLV27-1,NT-BGHcLV27-2	85.9,87.2	Released	ENCODE4

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
APEH	Product_ID: A304-808A Lot_ID: 1 Source: Bethyl Labs Target Name: APEH-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for APEH is not avaliable on ENCORE database.

Proteins bound to RNA

APEH RNA is bound by 22 proteins.

CanvasJS.com

eCLIP assay for APEH is not avaliable on ENCORE database.

22 proteins are bound to APEH RNA:

Show entries

Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr3	49713628	49713755	+	5'-UTR,CDS,intron-Distal,intron-Proximal	4.34999	15.46573	HepG2	PRPF8
chr3	49719110	49719194	+	3'-UTR,CDS,intron-Proximal	4.12919	15.09067	HepG2	SF3A3
chr3	49720678	49720808	+	3'-UTR,CDS	4.35965	13.47326	K562	PABPC4
chr3	49717032	49717077	+	3'-UTR,CDS,intron-Proximal	3.95316	12.96553	HepG2	PPIG
chr3	49716314	49716387	+	3'-UTR,CDS,intron-Proximal	3.52365	12.90417	HepG2	PPIG
chr3	49713487	49713535	+	5'-UTR,CDS,intron-Distal,intron-Proximal	3.59012	12.05994	HepG2	PPIG
chr3	49713346	49713399	+	5'-UTR,CDS	3.94243	11.83519	HepG2	PPIG
chr3	49714116	49714176	+	5'-UTR,CDS,intron-Proximal	4.68371	11.58765	HepG2	PRPF8
chr3	49715022	49715066	+	3'-UTR,CDS	4.67126	11.47295	HepG2	PPIG
chr3	49715052	49715111	+	3'-UTR,CDS,intron-Proximal	5.59032	11.30299	HepG2	PRPF8
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 69 entries

eCLIP assay for APEH is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for APEH is not available on ENCORE database.
109 RBPs can affect the levels of APEH.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for APEH is not available on ENCORE database.

109 RBPs can affect the gene expression of APEH :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
APEH	ENSG00000164062.8	1278.53120	3304.08040	-1.36980	83.93620	82.16640	HepG2	SRFBP1
APEH	ENSG00000164062.8	434.70490	1843.39380	-2.08430	74.54210	71.64230	K562	HNRNPC
APEH	ENSG00000164062.8	951.09650	3317.37540	-1.80240	57.70660	55.37140	K562	AQR
APEH	ENSG00000164062.8	1606.96230	3679.10440	-1.19500	44.23720	40.42790	K562	SUCLG1
APEH	ENSG00000164062.8	304.57710	894.39930	-1.55410	36.12290	33.35330	K562	U2AF2
APEH	ENSG00000164062.8	1434.71800	2623.47950	-0.87070	31.54770	29.83870	HepG2	SUCLG1
APEH	ENSG00000164062.8	2977.10470	1793.49350	0.73100	30.99110	29.66720	HepG2	ZNF622
APEH	ENSG00000164062.8	1526.25670	2531.98980	-0.73030	22.88190	20.88630	K562	MTPAP
APEH	ENSG00000164062.8	1897.66910	2844.08410	-0.58370	18.32040	16.22210	K562	SRPK2
APEH	ENSG00000164062.8	262.22980	893.76000	-1.76910	16.28820	14.21790	K562	G3BP2
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 131 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for APEH is not available on ENCORE database.

42 RBPs can affect the splicing of APEH :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	FDR	is_included	Cell Line	Affected by RBP
SE	APEH	ENSG00000164062.8	chr3	+	49713488	49713652	49713323	49713399	49713810	49713948	-0.09500	0.00000	excluded	HepG2	U2AF2
SE	APEH	ENSG00000164062.8	chr3	+	49713488	49713652	49713323	49713399	49713810	49713948	-0.07300	0.00003	excluded	K562	AQR
SE	APEH	ENSG00000164062.8	chr3	+	49713488	49713652	49713323	49713399	49713810	49713948	-0.25200	0.00000	excluded	K562	SF3B1
SE	APEH	ENSG00000164062.8	chr3	+	49717025	49717077	49716284	49716382	49717973	49718062	-0.11400	0.00000	excluded	K562	HNRNPC
SE	APEH	ENSG00000164062.8	chr3	+	49713488	49713652	49713323	49713399	49713810	49713948	-0.25500	0.00000	excluded	K562	HNRNPC
A3SS	APEH	ENSG00000164062.8	chr3	+	49713488	49713948	49713810	49713948	49713313	49713399	-0.28600	0.00000	shorter	HepG2	U2AF2
A3SS	APEH	ENSG00000164062.8	chr3	+	49713488	49713948	49713810	49713948	49713323	49713399	-0.49500	0.00000	shorter	K562	SF3B1
A3SS	APEH	ENSG00000164062.8	chr3	+	49713488	49713948	49713810	49713948	49713323	49713399	-0.52900	0.00000	shorter	K562	HNRNPC
RI	APEH	ENSG00000164062.8	chr3	+	49713488	49713948	49713488	49713652	49713810	49713948	0.06900	0.00014	included	HepG2	UCHL5
RI	APEH	ENSG00000164062.8	chr3	+	49713488	49713948	49713488	49713652	49713810	49713948	0.06700	0.00002	included	HepG2	PRPF8

Showing 1 to 10 of 88 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

APEH

General Information

Functions

Localization

Domains (AlphaFold: APEH)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for APEH is not avaliable on ENCORE database.

22 proteins are bound to APEH RNA:

eCLIP assay for APEH is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for APEH is not available on ENCORE database.

109 RBPs can affect the gene expression of APEH :

The Knockdown/knockout RNA-Seq assay for APEH is not available on ENCORE database.

42 RBPs can affect the splicing of APEH :

The Knockdown/knockout RNA-Seq assay for APEH is not avaliable on ENCORE database.